-
1
-
-
33746925579
-
Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1
-
DOI 10.1084/jem.20060336
-
Abraham SM, Lawrence T, Kleiman A, Warden P, Medghalchi M, Tuckermann J, et al,. (2006). Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1. J Exp Med 203: 1883-1889. (Pubitemid 44188463)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.8
, pp. 1883-1889
-
-
Abraham, S.M.1
Lawrence, T.2
Kleiman, A.3
Warden, P.4
Medghalchi, M.5
Tuckermann, J.6
Saklatvala, J.7
Clark, A.R.8
-
2
-
-
49449089908
-
Molecular mechanisms of corticosteroid resistance
-
Adcock IM, Barnes PJ, (2008). Molecular mechanisms of corticosteroid resistance. Chest 134: 394-401.
-
(2008)
Chest
, vol.134
, pp. 394-401
-
-
Adcock, I.M.1
Barnes, P.J.2
-
3
-
-
0028881859
-
Abnormal glucocorticoid receptor/AP-1 interaction in steroid resistant asthma
-
Adcock IM, Lane SJ, Brown CA, Lee TH, Barnes PJ, (1995). Abnormal glucocorticoid receptor/AP-1 interaction in steroid resistant asthma. J Exp Med 182: 1951-1958.
-
(1995)
J Exp Med
, vol.182
, pp. 1951-1958
-
-
Adcock, I.M.1
Lane, S.J.2
Brown, C.A.3
Lee, T.H.4
Barnes, P.J.5
-
5
-
-
33745802580
-
Brief report: Glucocorticoid receptor polymorphism affects transrepression but not transactivation
-
DOI 10.1210/jc.2005-2119
-
van den Akker EL, Russcher H, van Rossum EF, Brinkmann AO, de Jong FH, Hokken A, et al,. (2006). Glucocorticoid receptor polymorphism affects transrepression but not transactivation. J Clin Endocrinol Metab 91: 2800-2803. (Pubitemid 44024655)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.7
, pp. 2800-2803
-
-
Van Den Akker, E.L.T.1
Russcher, H.2
Van Rossum, E.F.C.3
Brinkmann, A.O.4
De Jong, F.H.5
Hokken, A.6
Pols, H.A.P.7
Koper, J.W.8
Lamberts, S.W.J.9
-
6
-
-
38949112833
-
Mechanisms of disease: Macrophage migration inhibitory factor in SLE, RA and atherosclerosis
-
DOI 10.1038/ncprheum0701, PII NCPRHEUM0701
-
Ayoub S, Hickey MJ, Morand EF, (2008). Mechanisms of disease: macrophage migration inhibitory factor in SLE, RA and atherosclerosis. Nat Clin Pract Rheumatol 4: 98-105. (Pubitemid 351217659)
-
(2008)
Nature Clinical Practice Rheumatology
, vol.4
, Issue.2
, pp. 98-105
-
-
Ayoub, S.1
Hickey, M.J.2
Morand, E.F.3
-
7
-
-
0030614484
-
2-adrenergic receptor function in human nasal mucosa
-
2-adrenergic receptor function in human nasal mucosa. Am J Respir Crit Care Med 155: 704-710. (Pubitemid 27085823)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.155
, Issue.2
, pp. 704-710
-
-
Baraniuk, J.N.1
Ali, M.2
Brody, D.3
Maniscalco, J.4
Gaumond, E.5
Fitzgerald, T.6
Wong, G.7
Yuta, A.8
Mak, J.C.W.9
Barnes, P.J.10
Bascom, R.11
Troost, T.12
-
8
-
-
0036153433
-
2-agonists and corticosteroids
-
DOI 10.1183/09031936.02.00283202
-
Barnes PJ, (2002). Scientific rationale for combination inhalers with a long-acting β2-agonists and corticosteroids. Eur Respir J 19: 182-191. (Pubitemid 34105586)
-
(2002)
European Respiratory Journal
, vol.19
, Issue.1
, pp. 182-191
-
-
Barnes, P.J.1
-
9
-
-
28844479963
-
Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment
-
DOI 10.1517/14728222.9.6.1111
-
Barnes PJ, (2005). Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment. Expert Opin Ther Targets 9: 1111-1121. (Pubitemid 41762867)
-
(2005)
Expert Opinion on Therapeutic Targets
, vol.9
, Issue.6
, pp. 1111-1121
-
-
Barnes, P.J.1
-
10
-
-
31944440761
-
Corticosteroid effects on cell signalling
-
DOI 10.1183/09031936.06.00125404
-
Barnes PJ, (2006a). Corticosteroid effects on cell signalling. Eur Respir J 27: 413-426. (Pubitemid 43185854)
-
(2006)
European Respiratory Journal
, vol.27
, Issue.2
, pp. 413-426
-
-
Barnes, P.J.1
-
11
-
-
33744477341
-
How corticosteroids control inflammation
-
Barnes PJ, (2006b). How corticosteroids control inflammation. Br J Pharmacol 148: 245-254.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 245-254
-
-
Barnes, P.J.1
-
12
-
-
33847748281
-
Scientific rationale for using a single inhaler for asthma control
-
DOI 10.1183/09031936.00080306
-
Barnes PJ, (2007). Scientific rationale for using a single inhaler for asthma control. Eur Resp Dis 29: 587-595. (Pubitemid 46372109)
-
(2007)
European Respiratory Journal
, vol.29
, Issue.3
, pp. 587-595
-
-
Barnes, P.J.1
-
13
-
-
55849148482
-
Cytokine networks in asthma and chronic obstructive pulmonary disease
-
Barnes PJ, (2008a). Cytokine networks in asthma and chronic obstructive pulmonary disease. J Clin Invest 118: 3546-3556.
-
(2008)
J Clin Invest
, vol.118
, pp. 3546-3556
-
-
Barnes, P.J.1
-
14
-
-
40049104892
-
Immunology of asthma and chronic obstructive pulmonary disease
-
DOI 10.1038/nri2254, PII NRI2254
-
Barnes PJ, (2008b). Immunology of asthma and chronic obstructive pulmonary disease. Nat Immunol Rev 8: 183-192. (Pubitemid 351323287)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.3
, pp. 183-192
-
-
Barnes, P.J.1
-
15
-
-
70449901337
-
Histone deacetylase-2 and airway disease
-
Barnes PJ, (2009a). Histone deacetylase-2 and airway disease. Ther Adv Respir Dis 3: 235-243.
-
(2009)
Ther Adv Respir Dis
, vol.3
, pp. 235-243
-
-
Barnes, P.J.1
-
16
-
-
59349084488
-
Role of HDAC2 in the pathophysiology of COPD
-
Barnes PJ, (2009b). Role of HDAC2 in the pathophysiology of COPD. Ann Rev Physiol 71: 451-464.
-
(2009)
Ann Rev Physiol
, vol.71
, pp. 451-464
-
-
Barnes, P.J.1
-
17
-
-
77954814658
-
Inhaled corticosteroids in COPD: A controversy
-
Barnes PJ, (2010a). Inhaled corticosteroids in COPD: a controversy. Respiration 80: 89-95.
-
(2010)
Respiration
, vol.80
, pp. 89-95
-
-
Barnes, P.J.1
-
18
-
-
77952951084
-
Mechanisms and resistance in glucocorticoid control of inflammation
-
Barnes PJ, (2010b). Mechanisms and resistance in glucocorticoid control of inflammation. J Steroid Biochem Mol Biol 120: 76-85.
-
(2010)
J Steroid Biochem Mol Biol
, vol.120
, pp. 76-85
-
-
Barnes, P.J.1
-
19
-
-
0141497509
-
How Do Corticosteroids Work in Asthma?
-
Barnes PJ, Adcock IM, (2003). How do corticosteroids work in asthma? Ann Intern Med 139: 359-370. (Pubitemid 38124591)
-
(2003)
Annals of Internal Medicine
, vol.139
, Issue.5
, pp. 359-370
-
-
Barnes, P.J.1
Adcock, I.M.2
-
20
-
-
65849427529
-
Glucocorticoid resistance in inflammatory diseases
-
Barnes PJ, Adcock IM, (2009). Glucocorticoid resistance in inflammatory diseases. Lancet 342: 1905-1917.
-
(2009)
Lancet
, vol.342
, pp. 1905-1917
-
-
Barnes, P.J.1
Adcock, I.M.2
-
22
-
-
1542301591
-
Corticosteroid resistance in chronic obstructive pulmonary disease: Inactivation of histone deacetylase
-
DOI 10.1016/S0140-6736(04)15650-X, PII S014067360415650X
-
Barnes PJ, Ito K, Adcock IM, (2004). A mechanism of corticosteroid resistance in COPD: inactivation of histone deacetylase. Lancet 363: 731-733. (Pubitemid 38296564)
-
(2004)
Lancet
, vol.363
, Issue.9410
, pp. 731-733
-
-
Barnes, P.J.1
Ito, K.2
Adcock, I.M.3
-
23
-
-
14744285888
-
Histone acetylation and deacetylation: Importance in inflammatory lung diseases
-
DOI 10.1183/09031936.05.00117504
-
Barnes PJ, Adcock IM, Ito K, (2005). Histone acetylation and deacetylation: importance in inflammatory lung diseases. Eur Respir J 25: 552-563. (Pubitemid 40331188)
-
(2005)
European Respiratory Journal
, vol.25
, Issue.3
, pp. 552-563
-
-
Barnes, P.J.1
Adcock, I.M.2
Ito, K.3
-
24
-
-
39049170984
-
Global strategy for asthma management and prevention: GINA executive summary
-
Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, Fitzgerald M, et al,. (2008). Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 31: 143-178.
-
(2008)
Eur Respir J
, vol.31
, pp. 143-178
-
-
Bateman, E.D.1
Hurd, S.S.2
Barnes, P.J.3
Bousquet, J.4
Drazen, J.M.5
Fitzgerald, M.6
-
25
-
-
0036561069
-
A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis
-
DOI 10.1038/sj.gene.6363867
-
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, et al,. (2002). A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun 3: 170-176. (Pubitemid 38961128)
-
(2002)
Genes and Immunity
, vol.3
, Issue.3
, pp. 170-176
-
-
Baugh, J.A.1
Chitnis, S.2
Donnelly, S.C.3
Monteiro, J.4
Lin, X.5
Plant, B.J.6
Wolfe, F.7
Gregersen, P.K.8
Bucala, R.9
-
26
-
-
1842556193
-
Glucocorticoid inhibition of GM-CSF from T cells is independent of control by NF-ÎB and CLE0
-
Bergmann MW, Staples KJ, Smith SJ, Barnes PJ, Newton R, (2004). Glucocorticoid inhibition of GM-CSF from T cells is independent of control by NF-ÎB and CLE0. Am J Respir Cell Mol Biol 30: 555-563.
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, pp. 555-563
-
-
Bergmann, M.W.1
Staples, K.J.2
Smith, S.J.3
Barnes, P.J.4
Newton, R.5
-
27
-
-
51249109929
-
Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared to non-severe asthma
-
Bhavsar P, Hew M, Khorasani N, Alfonso T, Barnes PJ, Adcock I, et al,. (2008). Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared to non-severe asthma. Thorax 63: 784-790.
-
(2008)
Thorax
, vol.63
, pp. 784-790
-
-
Bhavsar, P.1
Hew, M.2
Khorasani, N.3
Alfonso, T.4
Barnes, P.J.5
Adcock, I.6
-
28
-
-
36049046128
-
Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: A randomised controlled trial
-
DOI 10.1136/thx.2006.071068
-
Bourbeau J, Christodoulopoulos P, Maltais F, Yamauchi Y, Olivenstein R, Hamid Q, (2007). Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: a randomised controlled trial. Thorax 62: 938-943. (Pubitemid 350084490)
-
(2007)
Thorax
, vol.62
, Issue.11
, pp. 938-943
-
-
Bourbeau, J.1
Christodoulopoulos, P.2
Maltais, F.3
Yamauchi, Y.4
Olivenstein, R.5
Hamid, Q.6
-
29
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
DOI 10.1056/NEJMoa063070
-
Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, et al,. (2007). Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 356: 775-789. (Pubitemid 46294610)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.8
, pp. 775-789
-
-
Calverley, P.M.A.1
Anderson, J.A.2
Celli, B.3
Ferguson, G.T.4
Jenkins, C.5
Jones, P.W.6
Yates, J.C.7
Vestbo, J.8
-
30
-
-
69149103642
-
Roflumilast in symptomatic chronic obstructive pulmonary disease: Two randomised clinical trials
-
Calverley PM, Rabe KF, Goehring UM, Kristiansen S, Fabbri LM, Martinez FJ, (2009). Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 374: 685-694.
-
(2009)
Lancet
, vol.374
, pp. 685-694
-
-
Calverley, P.M.1
Rabe, K.F.2
Goehring, U.M.3
Kristiansen, S.4
Fabbri, L.M.5
Martinez, F.J.6
-
31
-
-
0019412311
-
Corticosteroid resistance in asthma
-
Carmichael J, Paterson IC, Diaz P, Crompton GK, Kay AB, Grant IWB, (1981). Corticosteroid resistance in asthma. Br Med J 282: 1419-1422.
-
(1981)
Br Med J
, vol.282
, pp. 1419-1422
-
-
Carmichael, J.1
Paterson, I.C.2
Diaz, P.3
Crompton, G.K.4
Kay, A.B.5
Grant, I.W.B.6
-
32
-
-
33745742455
-
Effects of smoking cessation on lung function and airway inflammation in smokers with asthma
-
DOI 10.1164/rccm.200510-1589OC
-
Chaudhuri R, Livingston E, McMahon AD, Lafferty J, Fraser I, Spears M, et al,. (2006). Effects of smoking cessation on lung function and airway inflammation in smokers with asthma. Am J Respir Crit Care Med 174: 127-133. (Pubitemid 44015385)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.2
, pp. 127-133
-
-
Chaudhuri, R.1
Livingston, E.2
McMahon, A.D.3
Lafferty, J.4
Fraser, I.5
Spears, M.6
McSharry, C.P.7
Thomson, N.C.8
-
33
-
-
0041669330
-
MAP kinase phosphatase 1: A novel mediator of biological effects of glucocorticoids?
-
DOI 10.1677/joe.0.1780005
-
Clark AR, (2003). MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids? J Endocrinol 178: 5-12. (Pubitemid 36927003)
-
(2003)
Journal of Endocrinology
, vol.178
, Issue.1
, pp. 5-12
-
-
Clark, A.R.1
-
34
-
-
4544379912
-
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages
-
DOI 10.1084/jem.20040416
-
Cosio BG, Tsaprouni L, Ito K, Jazrawi E, Adcock IM, Barnes PJ, (2004). Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J Exp Med 200: 689-695. (Pubitemid 39258317)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.5
, pp. 689-695
-
-
Cosio, B.G.1
Tsaprouni, L.2
Ito, K.3
Jazrawi, E.4
Adcock, I.M.5
Barnes, P.J.6
-
35
-
-
0032696013
-
Effect of high dose inhaled steroid on cells, cytokines and proteases in induced sputum in chronic obstructive pulmonary disease
-
Culpitt SV, Nightingale JA, Barnes PJ, (1999). Effect of high dose inhaled steroid on cells, cytokines and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160: 1635-1639.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1635-1639
-
-
Culpitt, S.V.1
Nightingale, J.A.2
Barnes, P.J.3
-
36
-
-
77952950546
-
Selective Glucocorticoid Receptor modulators
-
De Bosscher K, (2010). Selective Glucocorticoid Receptor modulators. J Steroid Biochem Mol Biol 120: 96-104.
-
(2010)
J Steroid Biochem Mol Biol
, vol.120
, pp. 96-104
-
-
De Bosscher, K.1
-
37
-
-
33846837071
-
Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII
-
DOI 10.1096/fj.06-7236com
-
Donn R, Berry A, Stevens A, Farrow S, Betts J, Stevens R, et al,. (2007). Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII. FASEB J 21: 402-414. (Pubitemid 46213488)
-
(2007)
FASEB Journal
, vol.21
, Issue.2
, pp. 402-414
-
-
Donn, R.1
Berry, A.2
Stevens, A.3
Farrow, S.4
Betts, J.5
Stevens, R.6
Clayton, C.7
Wang, J.8
Warnock, L.9
Worthington, J.10
Scott, L.11
Graham, S.12
Ray, D.13
-
38
-
-
4444289382
-
Negative glucocorticoid receptor response elements and their role in glucocorticoid action
-
DOI 10.2174/1381612043383601
-
Dostert A, Heinzel T, (2004). Negative glucocorticoid receptor response elements and their role in glucocorticoid action. Curr Pharm Des 10: 2807-2816. (Pubitemid 39162399)
-
(2004)
Current Pharmaceutical Design
, vol.10
, Issue.23
, pp. 2807-2816
-
-
Dostert, A.1
Heinzel, T.2
-
39
-
-
33750447625
-
The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs
-
DOI 10.1007/s00228-006-0192-1
-
Drozdzik M, Rudas T, Pawlik A, Kurzawski M, Czerny B, Gornik W, et al,. (2006). The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs. Eur J Clin Pharmacol 62: 933-937. (Pubitemid 44657627)
-
(2006)
European Journal of Clinical Pharmacology
, vol.62
, Issue.11
, pp. 933-937
-
-
Drozdzik, M.1
Rudas, T.2
Pawlik, A.3
Kurzawski, M.4
Czerny, B.5
Gornik, W.6
Herczynska, M.7
-
40
-
-
54249100556
-
Rapid anti-inflammatory effect of inhaled ciclesonide in asthma: A randomised, placebo-controlled study
-
Erin EM, Zacharasiewicz AS, Nicholson GC, Tan AJ, Neighbour H, Engelstatter R, et al,. (2008). Rapid anti-inflammatory effect of inhaled ciclesonide in asthma: a randomised, placebo-controlled study. Chest 134: 740-745.
-
(2008)
Chest
, vol.134
, pp. 740-745
-
-
Erin, E.M.1
Zacharasiewicz, A.S.2
Nicholson, G.C.3
Tan, A.J.4
Neighbour, H.5
Engelstatter, R.6
-
41
-
-
0037501014
-
Cyclosporin as an oral corticosteroid sparing agent in stable asthma (Cochrane Review)
-
Evans DJ, Cullinan P, Geddes DM, (2001). Cyclosporin as an oral corticosteroid sparing agent in stable asthma (Cochrane Review). Cochrane Database Syst Rev 2: CD002993.
-
(2001)
Cochrane Database Syst Rev
, vol.2
-
-
Evans, D.J.1
Cullinan, P.2
Geddes, D.M.3
-
42
-
-
2442466059
-
Microbial Superantigens Induce Glucocorticoid Receptor β and Steroid Resistance in a Nasal Explant Model
-
DOI 10.1097/00005537-200405000-00019
-
Fakhri S, Tulic M, Christodoulopoulos P, Fukakusa M, Frenkiel S, Leung DY, et al,. (2004). Microbial superantigens induce glucocorticoid receptor beta and steroid resistance in a nasal explant model. Laryngoscope 114: 887-892. (Pubitemid 38625543)
-
(2004)
Laryngoscope
, vol.114
, Issue.5
, pp. 887-892
-
-
Fakhri, S.1
Tulic, M.2
Christodoulopoulos, P.3
Fukakusa, M.4
Frenkiel, S.5
Leung, D.Y.M.6
Hamid, Q.A.7
-
43
-
-
0141619279
-
Glucocorticoid resistance in inflammatory bowel disease
-
DOI 10.1677/joe.0.1780339
-
Farrell RJ, Kelleher D, (2003). Glucocorticoid resistance in inflammatory bowel disease. J Endocrinol 178: 339-346. (Pubitemid 37220161)
-
(2003)
Journal of Endocrinology
, vol.178
, Issue.3
, pp. 339-346
-
-
Farrell, R.J.1
Kelleher, D.2
-
44
-
-
0033959944
-
High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy
-
Farrell RJ, Murphy A, Long A, Donnelly S, Cherikuri A, O'Toole D, et al,. (2000). High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy. Gastroenterology 118: 279-288. (Pubitemid 30067501)
-
(2000)
Gastroenterology
, vol.118
, Issue.2
, pp. 279-288
-
-
Farrell, R.J.1
Murphy, A.2
Long, A.3
Donnelly, S.4
Cherikuri, A.5
O'Toole, D.6
Mahmud, N.7
Keeling, P.W.N.8
Weir, D.G.9
Kelleher, D.10
-
45
-
-
34250832623
-
The macrophage migration inhibitory factor-glucocorticoid dyad: Regulation of inflammation and immunity
-
DOI 10.1210/me.2007-0065
-
Flaster H, Bernhagen J, Calandra T, Bucala R, (2007). The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. Mol Endocrinol 21: 1267-1280. (Pubitemid 46984737)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.6
, pp. 1267-1280
-
-
Flaster, H.1
Bernhagen, J.2
Calandra, T.3
Bucala, R.4
-
46
-
-
77953310216
-
Treatment effects of low dose theophylline combined with an inhaled corticosteroid in COPD
-
Ford PA, Durham AL, Russell REK, Gordon F, Adcock IM, Barnes PJ, (2010). Treatment effects of low dose theophylline combined with an inhaled corticosteroid in COPD. Chest 137: 1338-1344.
-
(2010)
Chest
, vol.137
, pp. 1338-1344
-
-
Ford, P.A.1
Durham, A.L.2
Russell, R.E.K.3
Gordon, F.4
Adcock, I.M.5
Barnes, P.J.6
-
47
-
-
44649174528
-
Oral or inhaled corticosteroid combination therapy with low dose theophylline reverses corticosteroid insensitivity in a smoking mouse model
-
Fox JC, Spicer D, Ito K, Barnes PJ, Fitzgerald MF, (2007). Oral or inhaled corticosteroid combination therapy with low dose theophylline reverses corticosteroid insensitivity in a smoking mouse model. Proc Am Thorac Soc 2: A637.
-
(2007)
Proc Am Thorac Soc
, vol.2
-
-
Fox, J.C.1
Spicer, D.2
Ito, K.3
Barnes, P.J.4
Fitzgerald, M.F.5
-
48
-
-
0033930349
-
Glucocorticoid receptor α and β in glucocorticoid dependent asthma
-
Gagliardo R, Chanez P, Vignola AM, Bousquet J, Vachier I, Godard P, et al,. (2000). Glucocorticoid receptor α and β in glucocorticoid dependent asthma. Am J Respir Crit Care Med 162: 7-13.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 7-13
-
-
Gagliardo, R.1
Chanez, P.2
Vignola, A.M.3
Bousquet, J.4
Vachier, I.5
Godard, P.6
-
50
-
-
68049084752
-
The overlap syndrome of asthma and COPD: What are its features and how important is it?
-
Gibson PG, Simpson JL, (2009). The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax 64: 728-735.
-
(2009)
Thorax
, vol.64
, pp. 728-735
-
-
Gibson, P.G.1
Simpson, J.L.2
-
52
-
-
33846787098
-
Differential effects of maintenance long-acting β-agonist and inhaled corticosteroid on asthma control and asthma exacerbations
-
DOI 10.1016/j.jaci.2006.10.043, PII S0091674906030259
-
Gibson PG, Powell H, Ducharme FM, (2007). Differential effects of maintenance long-acting beta-agonist and inhaled corticosteroid on asthma control and asthma exacerbations. J Allergy Clin Immunol 119: 344-350. (Pubitemid 46206143)
-
(2007)
Journal of Allergy and Clinical Immunology
, vol.119
, Issue.2
, pp. 344-350
-
-
Gibson, P.G.1
Powell, H.2
Ducharme, F.M.3
-
53
-
-
40949165358
-
2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids
-
DOI 10.1038/sj.bjp.0707627, PII 0707627
-
Giembycz MA, Kaur M, Leigh R, Newton R, (2008). A Holy Grail of asthma management: toward understanding how long-acting beta(2)-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids. Br J Pharmacol 153: 1090-1104. (Pubitemid 351415494)
-
(2008)
British Journal of Pharmacology
, vol.153
, Issue.6
, pp. 1090-1104
-
-
Giembycz, M.A.1
Kaur, M.2
Leigh, R.3
Newton, R.4
-
54
-
-
4444291705
-
Importin α: A multipurpose nuclear-transport receptor
-
DOI 10.1016/j.tcb.2004.07.016, PII S0962892404001953
-
Goldfarb DS, Corbett AH, Mason DA, Harreman MT, Adam SA, (2004). Importin alpha: a multipurpose nuclear-transport receptor. Trends Cell Biol 14: 505-514. (Pubitemid 39209358)
-
(2004)
Trends in Cell Biology
, vol.14
, Issue.9
, pp. 505-514
-
-
Goldfarb, D.S.1
Corbett, A.H.2
Mason, D.A.3
Harreman, M.T.4
Adam, S.A.5
-
55
-
-
0037111418
-
A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance
-
Goleva E, Kisich KO, Leung DY, (2002). A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance. J Immunol 169: 5934-5940. (Pubitemid 35291700)
-
(2002)
Journal of Immunology
, vol.169
, Issue.10
, pp. 5934-5940
-
-
Goleva, E.1
Kisich, K.O.2
Leung, D.Y.M.3
-
56
-
-
33644834415
-
Increased glucocorticoid receptor β alters steroid response in glucocorticoid-insensitive asthma
-
DOI 10.1164/rccm.200507-1046OC
-
Goleva E, Li LB, Eves PT, Strand MJ, Martin RJ, Leung DY, (2006). Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma. Am J Respir Crit Care Med 173: 607-616. (Pubitemid 43363801)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.6
, pp. 607-616
-
-
Goleva, E.1
Li, L.-B.2
Eves, P.T.3
Strand, M.J.4
Martin, R.J.5
Leung, D.Y.M.6
-
57
-
-
34250212850
-
A polymorphism in the macrophage migration inhibitory factor gene is involved in the genetic predisposition of Crohn's disease and associated with cumulative steroid doses
-
Griga T, Wilkens C, Wirkus N, Epplen J, Schmiegel W, Klein W, (2007). A polymorphism in the macrophage migration inhibitory factor gene is involved in the genetic predisposition of Crohn's disease and associated with cumulative steroid doses. Hepatogastroenterology 54: 784-786. (Pubitemid 46903723)
-
(2007)
Hepato-Gastroenterology
, vol.54
, Issue.75
, pp. 784-786
-
-
Griga, T.1
Wilkens, C.2
Wirkus, N.3
Epplen, J.4
Schmiegel, W.5
Klein, W.6
-
58
-
-
26844520628
-
Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
-
DOI 10.1073/pnas.0409904102
-
Hakonarson H, Bjornsdottir US, Halapi E, Bradfield J, Zink F, Mouy M, et al,. (2005). Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients. Proc Natl Acad Sci U S A 102: 14789-14794. (Pubitemid 41457134)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.41
, pp. 14789-14794
-
-
Hakonarson, H.1
Bjornsdottir, U.S.2
Halapi, E.3
Bradfield, J.4
Zink, F.5
Mouy, M.6
Helgadottir, H.7
Gudmundsdottir, A.S.8
Andrason, H.9
Adalsteinsdottir, A.E.10
Kristjansson, K.11
Birkisson, I.12
Arnason, T.13
Andresdottir, M.14
Gislason, D.15
Gislason, T.16
Gulcher, J.R.17
Stefansson, K.18
-
59
-
-
0032914288
-
Increased glucocorticoid receptor β in airway cells of glucocorticoid- insensitive asthma
-
Hamid QA, Wenzel SE, Hauk PJ, Tsicopoulos A, Wallaert B, Lafitte JJ, et al,. (1999). Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma. Am J Respir Crit Care Med 159: 1600-1604. (Pubitemid 29227876)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.159
, Issue.5
, pp. 1600-1604
-
-
Hamid, Q.A.1
Wenzel, S.E.2
Hauk, P.J.3
Tsicopoulos, A.4
Wallaert, B.5
Lafitte, J.-J.6
Chrousos, G.P.7
Szefler, S.J.8
Leung, D.Y.M.9
-
60
-
-
0037097883
-
The effects of inhaled fluticasone on airway inflammation in Chronic Obstructive Pulmonary Disease: A double-blind, placebo-controlled biopsy study
-
DOI 10.1164/rccm.2105025
-
Hattotuwa KL, Gizycki MJ, Ansari TW, Jeffery PK, Barnes NC, (2002). The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: a double-blind, placebo-controlled biopsy study. Am J Respir Crit Care Med 165: 1592-1596. (Pubitemid 34693937)
-
(2002)
American Journal of Respiratory and Critical Care Medicine
, vol.165
, Issue.12
, pp. 1592-1596
-
-
Hattotuwa, K.L.1
Gizycki, M.J.2
Ansari, T.W.3
Jeffery, P.K.4
Barnes, N.C.5
-
61
-
-
77953105482
-
The preclinical pharmacology of roflumilast - A selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease
-
Hatzelmann A, Morcillo EJ, Lungarella G, Adnot S, Sanjar S, Beume R, et al,. (2010). The preclinical pharmacology of roflumilast-a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease. Pulm Pharmacol Ther 23: 235-256.
-
(2010)
Pulm Pharmacol Ther
, vol.23
, pp. 235-256
-
-
Hatzelmann, A.1
Morcillo, E.J.2
Lungarella, G.3
Adnot, S.4
Sanjar, S.5
Beume, R.6
-
62
-
-
28544433747
-
Regulatory T cells and IL-10 in allergic inflammation
-
DOI 10.1084/jem.20052211
-
Hawrylowicz CM, (2005). Regulatory T cells and IL-10 in allergic inflammation. J Exp Med 202: 1459-1463. (Pubitemid 41746591)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.11
, pp. 1459-1463
-
-
Hawrylowicz, C.M.1
-
63
-
-
33745746529
-
Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma
-
DOI 10.1164/rccm.200512-1930OC
-
Hew M, Bhavsar P, Torrego A, Meah S, Khorasani N, Barnes PJ, et al,. (2006). Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma. Am J Respir Crit Care Med 174: 134-141. (Pubitemid 44015386)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.2
, pp. 134-141
-
-
Hew, M.1
Bhavsar, P.2
Torrego, A.3
Meah, S.4
Khorasani, N.5
Barnes, P.J.6
Adcock, I.7
Kian, F.C.8
-
64
-
-
34648819347
-
Macrophage migration inhibitory factor: A therapeutic target across inflammatory diseases
-
DOI 10.2174/187152807781696455
-
Hoi AY, Iskander MN, Morand EF, (2007). Macrophage migration inhibitory factor: a therapeutic target across inflammatory diseases. Inflamm Allergy Drug Targets 6: 183-190. (Pubitemid 47455787)
-
(2007)
Inflammation and Allergy - Drug Targets
, vol.6
, Issue.3
, pp. 183-190
-
-
Hoi, A.Y.1
Iskander, M.N.2
Morand, E.F.3
-
65
-
-
0036231010
-
P38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
-
DOI 10.1067/mai.2002.122465
-
Irusen E, Matthews JG, Takahashi A, Barnes PJ, Chung KF, Adcock IM, (2002). p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma. J Allergy Clin Immunol 109: 649-657. (Pubitemid 34327193)
-
(2002)
Journal of Allergy and Clinical Immunology
, vol.109
, Issue.4
, pp. 649-657
-
-
Irusen, E.1
Matthews, J.G.2
Takahashi, A.3
Barnes, P.J.4
Chung, K.F.5
Adcock, I.M.6
-
66
-
-
33746785986
-
Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis
-
DOI 10.1016/j.clim.2006.05.010, PII S1521661606007479
-
Ishiguro Y, Ohkawara T, Sakuraba H, Yamagata K, Hiraga H, Yamaguchi S, et al,. (2006). Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis. Clin Immunol 120: 335-341. (Pubitemid 44175900)
-
(2006)
Clinical Immunology
, vol.120
, Issue.3
, pp. 335-341
-
-
Ishiguro, Y.1
Ohkawara, T.2
Sakuraba, H.3
Yamagata, K.4
Hiraga, H.5
Yamaguchi, S.6
Fukuda, S.7
Munakata, A.8
Nakane, A.9
Nishihira, J.10
-
67
-
-
3042788350
-
Modulation of glucocorticoid receptor function via phosphorylation
-
DOI 10.1196/annals.1321.007
-
Ismaili N, Garabedian MJ, (2004). Modulation of glucocorticoid receptor function via phosphorylation. Ann N Y Acad Sci 1024: 86-101. (Pubitemid 38879595)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1024
, pp. 86-101
-
-
Ismaili, N.1
Garabedian, M.J.2
-
68
-
-
0033821409
-
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits IL-1β-induced histone H4 acetylation on lysines 8 and 12
-
Ito K, Barnes PJ, Adcock IM, (2000). Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits IL-1β-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 20: 6891-6903.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6891-6903
-
-
Ito, K.1
Barnes, P.J.2
Adcock, I.M.3
-
69
-
-
0842308109
-
Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: Role of tyrosine nitration
-
DOI 10.1016/j.bbrc.2004.01.046
-
Ito K, Tomita T, Barnes PJ, Adcock IM, (2004). Oxidative stress reduces histone deacetylase (HDAC)2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem Biophys Res Commun 315: 240-245. (Pubitemid 38175212)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.315
, Issue.1
, pp. 240-245
-
-
Ito, K.1
Hanazawa, T.2
Tomita, K.3
Barnes, P.J.4
Adcock, I.M.5
-
70
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
DOI 10.1056/NEJMoa041892
-
Ito K, Ito M, Elliott WM, Cosio B, Caramori G, Kon OM, et al,. (2005). Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 352: 1967-1976. (Pubitemid 40638367)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.19
, pp. 1967-1976
-
-
Ito, K.1
Ito, M.2
Elliott, W.M.3
Cosio, B.4
Caramori, G.5
Onn, M.K.6
Barczyk, A.7
Hayashi, S.8
Adcock, I.M.9
Hogg, J.C.10
Barnes, P.J.11
-
71
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
-
DOI 10.1084/jem.20050466
-
Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, et al,. (2006). Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-ÎB suppression. J Exp Med 203: 7-13. (Pubitemid 43139638)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.1
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
Adcock, I.M.7
-
72
-
-
40649106738
-
Interaction of the Glucocorticoid Receptor with the Chromatin Landscape
-
DOI 10.1016/j.molcel.2008.02.010, PII S1097276508001299
-
John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, et al,. (2008). Interaction of the glucocorticoid receptor with the chromatin landscape. Mol Cell 29: 611-624. (Pubitemid 351374691)
-
(2008)
Molecular Cell
, vol.29
, Issue.5
, pp. 611-624
-
-
John, S.1
Sabo, P.J.2
Johnson, T.A.3
Sung, M.-H.4
Biddie, S.C.5
Lightman, S.L.6
Voss, T.C.7
Davis, S.R.8
Meltzer, P.S.9
Stamatoyannopoulos, J.A.10
Hager, G.L.11
-
73
-
-
0025650904
-
Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics
-
Juniper EF, Kline PA, Yan Zieleshem MA, Ramsdale EH, O'Byrne PM, Hargreave FE, (1990). Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics. Eur Respir J 3: 1122-1127.
-
(1990)
Eur Respir J
, vol.3
, pp. 1122-1127
-
-
Juniper, E.F.1
Kline, P.A.2
Yan Zieleshem, M.A.3
Ramsdale, E.H.4
O'Byrne, P.M.5
Hargreave, F.E.6
-
74
-
-
0031045482
-
Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD
-
Keatings VM, Jatakanon A, Worsdell YM, Barnes PJ, (1997). Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 155: 542-548. (Pubitemid 27085799)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.155
, Issue.2
, pp. 542-548
-
-
Keatings, V.M.1
Jatakanon, A.2
Worsdell, Y.M.3
Barnes, P.J.4
-
75
-
-
0036793972
-
Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5′-monophosphate in mild asthma
-
DOI 10.1067/mai.2002.128486
-
Ketchell RI, Jensen MW, Lumley P, Wright AM, Allenby MI, O'Connor BJ, (2002). Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5'-monophosphate in mild asthma. J Allergy Clin Immunol 110: 603-606. (Pubitemid 35178796)
-
(2002)
Journal of Allergy and Clinical Immunology
, vol.110
, Issue.4
, pp. 603-606
-
-
Ketchell, R.I.1
Jensen, M.W.2
Lumley, P.3
Wright, A.M.4
Allenby, M.I.5
O'Connor, B.J.6
-
76
-
-
34247161833
-
Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis
-
DOI 10.1097/BOR.0b013e328099af80, PII 0000228120070500000003
-
Kitahara K, Kawai S, (2007). Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis. Curr Opin Rheumatol 19: 238-245. (Pubitemid 46597460)
-
(2007)
Current Opinion in Rheumatology
, vol.19
, Issue.3
, pp. 238-245
-
-
Kitahara, K.1
Kawai, S.2
-
77
-
-
34547872354
-
Glucocorticoid receptor action in beneficial and side effects of steroid therapy: Lessons from conditional knockout mice
-
DOI 10.1016/j.mce.2007.05.009, PII S0303720707001931
-
Kleiman A, Tuckermann JP, (2007). Glucocorticoid receptor action in beneficial and side effects of steroid therapy: lessons from conditional knockout mice. Mol Cell Endocrinol 275: 98-108. (Pubitemid 47259279)
-
(2007)
Molecular and Cellular Endocrinology
, vol.275
, Issue.1-2
, pp. 98-108
-
-
Kleiman, A.1
Tuckermann, J.P.2
-
78
-
-
21144444486
-
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
-
DOI 10.1016/j.molcel.2005.04.021, PII S1097276505012840
-
Kovacs JJ, Murphy PJ, Gaillard S, Zhao X, Wu JT, Nicchitta CV, et al,. (2005). HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Mol Cell 18: 601-607. (Pubitemid 40726236)
-
(2005)
Molecular Cell
, vol.18
, Issue.5
, pp. 601-607
-
-
Kovacs, J.J.1
Murphy, P.J.M.2
Gaillard, S.3
Zhao, X.4
Wu, J.-T.5
Nicchitta, C.V.6
Yoshida, M.7
Toft, D.O.8
Pratt, W.B.9
Yao, T.-P.10
-
79
-
-
34047123776
-
The differential expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis
-
DOI 10.1093/rheumatology/kel276
-
Kozaci DL, Chernajovsky Y, Chikanza IC, (2007). The differential expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis. Rheumatology (Oxford) 46: 579-585. (Pubitemid 46523299)
-
(2007)
Rheumatology
, vol.46
, Issue.4
, pp. 579-585
-
-
Kozaci, D.L.1
Chernajovsky, Y.2
Chikanza, I.C.3
-
80
-
-
0035321723
-
Hereditary glucocorticoid resistance
-
Lamberts SW, (2001). Hereditary glucocorticoid resistance. Ann Endocrinol (Paris) 62: 164-167.
-
(2001)
Ann Endocrinol (Paris)
, vol.62
, pp. 164-167
-
-
Lamberts, S.W.1
-
81
-
-
0028472787
-
Chemical mutational analysis of the human glucocortiocoid receptor cDNA in glucocorticoid-resistant bronchial asthma
-
Lane SJ, Arm JP, Staynov DZ, Lee TH, (1994). Chemical mutational analysis of the human glucocortiocoid receptor cDNA in glucocorticoid-resistant bronchial asthma. Am J Respir Cell Mol Biol 11: 42-48.
-
(1994)
Am J Respir Cell Mol Biol
, vol.11
, pp. 42-48
-
-
Lane, S.J.1
Arm, J.P.2
Staynov, D.Z.3
Lee, T.H.4
-
82
-
-
0032535369
-
Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
-
Lane SJ, Adcock IM, Richards D, Hawrylowicz C, Barnes PJ, Lee TH, (1998). Corticosteroid-resistant bronchial asthma is associated with increased c-Fos expression in monocytes and T-lymphocytes. J Clin Invest 102: 2156-2164. (Pubitemid 29018822)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.12
, pp. 2156-2164
-
-
Lane, S.J.1
Adcock, I.M.2
Richards, D.3
Hawrylowicz, C.4
Barnes, P.J.5
Tak, H.L.6
-
83
-
-
0028944915
-
Dysregulation of interleukin 4, interleukin 5, and interferon y gene expression in steroid-resistant asthma
-
Leung DYM, Martin RJ, Szefler SJ, Sher ER, Ying S, Kay AB, et al,. (1995). Dysregulation of interleukin 4, interleukin 5, and interferon y gene expression in steroid-resistant asthma. J Exp Med 181: 33-40.
-
(1995)
J Exp Med
, vol.181
, pp. 33-40
-
-
Leung, D.Y.M.1
Martin, R.J.2
Szefler, S.J.3
Sher, E.R.4
Ying, S.5
Kay, A.B.6
-
84
-
-
33745625334
-
The physiology of human glucocorticoid receptor β (hGRβ) and glucocorticoid resistance
-
DOI 10.1196/annals.1351.001
-
Lewis-Tuffin LJ, Cidlowski JA, (2006). The physiology of human glucocorticoid receptor beta (hGRbeta) and glucocorticoid resistance. Ann N Y Acad Sci 1069: 1-9. (Pubitemid 43989846)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1069
, pp. 1-9
-
-
Lewis-Tuffin, L.J.1
Cidlowski, J.A.2
-
85
-
-
33947247588
-
Human glucocorticoid receptor β binds RU-486 and is transcriptionally active
-
DOI 10.1128/MCB.01439-06
-
Lewis-Tuffin LJ, Jewell CM, Bienstock RJ, Collins JB, Cidlowski JA, (2007). Human glucocorticoid receptor beta binds RU-486 and is transcriptionally active. Mol Cell Biol 27: 2266-2282. (Pubitemid 46418481)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.6
, pp. 2266-2282
-
-
Lewis-Tuffin, L.J.1
Jewell, C.M.2
Bienstock, R.J.3
Collins, J.B.4
Cidlowski, J.A.5
-
86
-
-
7944220552
-
Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway
-
DOI 10.1016/j.jaci.2004.08.005, PII S0091674904021943
-
Li LB, Goleva E, Hall CF, Ou LS, Leung DY, (2004). Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway. J Allergy Clin Immunol 114: 1059-1069. (Pubitemid 39469145)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.114
, Issue.5
, pp. 1059-1069
-
-
Li, L.-B.1
Goleva, E.2
Hall, C.F.3
Ou, L.-S.4
Leung, D.Y.M.5
-
87
-
-
33746674992
-
Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid- resistant asthmatic patients
-
DOI 10.1016/j.jaci.2006.04.055, PII S0091674906010566
-
Loke TK, Mallett KH, Ratoff J, O'Connor BJ, Ying S, Meng Q, et al,. (2006). Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients. J Allergy Clin Immunol 118: 368-375. (Pubitemid 44160720)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.118
, Issue.2
, pp. 368-375
-
-
Loke, T.-K.1
Mallett, K.H.2
Ratoff, J.3
O'Connor, B.J.4
Ying, S.5
Meng, Q.6
Soh, C.7
Lee, T.H.8
Corrigan, C.J.9
-
88
-
-
0034942614
-
In patients with chronic bronchitis a four week trial with inhaled steroids does not attenuate airway inflammation
-
DOI 10.1053/rmed.2000.0960
-
Loppow D, Schleiss MB, Kanniess F, Taube C, Jorres RA, Magnussen H, (2001). In patients with chronic bronchitis a four week trial with inhaled steroids does not attenuate airway inflammation. Respir Med 95: 115-121. (Pubitemid 32624442)
-
(2001)
Respiratory Medicine
, vol.95
, Issue.2
, pp. 115-121
-
-
Loppow, D.1
Schleiss, M.B.2
Kanniess, F.3
Taube, C.4
Jorres, R.A.5
Magnussen, H.6
-
89
-
-
3042831099
-
The origin and functions of multiple human glucocorticoid receptor isoforms
-
DOI 10.1196/annals.1321.008
-
Lu NZ, Cidlowski JA, (2004). The origin and functions of multiple human glucocorticoid receptor isoforms. Ann N Y Acad Sci 1024: 102-123. (Pubitemid 38879596)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1024
, pp. 102-123
-
-
Nick, Z.L.U.1
Cidlowski, J.A.2
-
90
-
-
0037006417
-
Increased expression of G protein-coupled receptor kinases in cystic fibrosis lung
-
DOI 10.1016/S0014-2999(01)01625-9, PII S0014299901016259
-
Mak JC, Chuang TT, Harris CA, Barnes PJ, (2002). Increased expression of G protein-coupled receptor kinases in cystic fibrosis lung. Eur J Pharmacol 436: 165-172. (Pubitemid 34164696)
-
(2002)
European Journal of Pharmacology
, vol.436
, Issue.3
, pp. 165-172
-
-
Mak, J.C.W.1
Chuang, T.-T.2
Harris, C.A.3
Barnes, P.J.4
-
93
-
-
33846935457
-
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
-
Maneechotesuwan K, Xin Y, Ito K, Jazrawi E, Lee KY, Usmani OS, et al,. (2007). Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. J Immunol 178: 2491-2498. (Pubitemid 46233450)
-
(2007)
Journal of Immunology
, vol.178
, Issue.4
, pp. 2491-2498
-
-
Maneechotesuwan, K.1
Xin, Y.2
Ito, K.3
Jazrawi, E.4
Lee, K.-Y.5
Usmani, O.S.6
Barnes, P.J.7
Adcock, I.M.8
-
94
-
-
38149085198
-
Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids
-
Maneechotesuwan K, Supawita S, Kasetsinsombat K, Wongkajornsilp A, Barnes PJ, (2008). Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids. J Allergy Clin Immunol 121: 43-50.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 43-50
-
-
Maneechotesuwan, K.1
Supawita, S.2
Kasetsinsombat, K.3
Wongkajornsilp, A.4
Barnes, P.J.5
-
95
-
-
66349134442
-
Suppression of GATA-3 nuclear import and phosphorylation: A novel mechanism of corticosteroid action in allergic disease
-
Maneechotesuwan K, Yao X, Ito K, Jazrawi E, Usmani OS, Adcock IM, et al,. (2009). Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease. PLoS Med 6: e1000076.
-
(2009)
PLoS Med
, vol.6
-
-
Maneechotesuwan, K.1
Yao, X.2
Ito, K.3
Jazrawi, E.4
Usmani, O.S.5
Adcock, I.M.6
-
96
-
-
77957788255
-
Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase
-
Maneechotesuwan K, Ekjiratrakul W, Kasetsinsombat K, Wongkajornsilp A, Barnes PJ, (2010). Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase. J Allergy Clin Immunol 126: 754-762.
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 754-762
-
-
Maneechotesuwan, K.1
Ekjiratrakul, W.2
Kasetsinsombat, K.3
Wongkajornsilp, A.4
Barnes, P.J.5
-
97
-
-
65249151877
-
Inhibition of PI3KÎ restores glucocorticoid function in smoking-induced airway inflammation in mice
-
Marwick JA, Caramori G, Stevenson CC, Casolari P, Jazrawi E, Barnes PJ, et al,. (2009). Inhibition of PI3KÎ restores glucocorticoid function in smoking-induced airway inflammation in mice. Am J Respir Crit Care Med 179: 542-548.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 542-548
-
-
Marwick, J.A.1
Caramori, G.2
Stevenson, C.C.3
Casolari, P.4
Jazrawi, E.5
Barnes, P.J.6
-
98
-
-
77951667667
-
A role for phosphoinositol 3-kinase delta in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease
-
Marwick JA, Caramori G, Casolari P, Mazzoni F, Kirkham PA, Adcock IM, et al,. (2010). A role for phosphoinositol 3-kinase delta in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol 125: 1146-1153.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1146-1153
-
-
Marwick, J.A.1
Caramori, G.2
Casolari, P.3
Mazzoni, F.4
Kirkham, P.A.5
Adcock, I.M.6
-
99
-
-
2342567291
-
Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients
-
DOI 10.1016/j.jaci.2004.03.018, PII S0091674904011509
-
Matthews JG, Ito K, Barnes PJ, Adcock IM, (2004). Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients. J Allergy Clin Immunol 113: 1100-1108. (Pubitemid 38857992)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.113
, Issue.6
, pp. 1100-1108
-
-
Matthews, J.G.1
Ito, K.2
Barnes, P.J.3
Adcock, I.M.4
-
100
-
-
40849119969
-
P38α-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation
-
DOI 10.1124/jpet.107.127092
-
Medicherla S, Fitzgerald M, Spicer D, Woodman P, Ma JY, Kapoun AM, et al,. (2007). p38α selective MAP kinase inhibitor, SD-282, reduces inflammation in a sub-chronic model of tobacco smoke-induced airway inflammation. J Pharmacol Exp Ther 324: 921-929. (Pubitemid 351397845)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.3
, pp. 921-929
-
-
Medicherla, S.1
Fitzgerald, M.F.2
Spicer, D.3
Woodman, P.4
Ma, J.Y.5
Kapoun, A.M.6
Chakravarty, S.7
Dugar, S.8
Protter, A.A.9
Higgins, L.S.10
-
101
-
-
22344458207
-
P38 mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: Correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211
-
DOI 10.1210/me.2004-0528
-
Miller AL, Webb MS, Copik AJ, Wang Y, Johnson BH, Kumar R, et al,. (2005). p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211. Mol Endocrinol 19: 1569-1583. (Pubitemid 41002986)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.6
, pp. 1569-1583
-
-
Miller, A.L.1
Webb, M.S.2
Copik, A.J.3
Wang, Y.4
Johnson, B.H.5
Kumar, R.6
Thompson, E.B.7
-
102
-
-
28844439445
-
Reduction is histone deacetylase expression and activity in smoking asthmatics: A mechanism of steroid resistance
-
Murahidy A, Ito M, Adcock IM, Barnes PJ, Ito K, (2005). Reduction is histone deacetylase expression and activity in smoking asthmatics: a mechanism of steroid resistance. Proc Am Thorac Soc 2: A889.
-
(2005)
Proc Am Thorac Soc
, vol.2
-
-
Murahidy, A.1
Ito, M.2
Adcock, I.M.3
Barnes, P.J.4
Ito, K.5
-
103
-
-
77349101801
-
Pharmacological strategies for improving the efficacy and therapeutic ratio of glucocorticoids in inflammatory lung diseases
-
Newton R, Leigh R, Giembycz MA, (2010). Pharmacological strategies for improving the efficacy and therapeutic ratio of glucocorticoids in inflammatory lung diseases. Pharmacol Ther 125: 286-327.
-
(2010)
Pharmacol Ther
, vol.125
, pp. 286-327
-
-
Newton, R.1
Leigh, R.2
Giembycz, M.A.3
-
104
-
-
71849112377
-
The human glucocorticoid receptor: Molecular basis of biologic function
-
Nicolaides NC, Galata Z, Kino T, Chrousos GP, Charmandari E, (2010). The human glucocorticoid receptor: molecular basis of biologic function. Steroids 75: 1-12.
-
(2010)
Steroids
, vol.75
, pp. 1-12
-
-
Nicolaides, N.C.1
Galata, Z.2
Kino, T.3
Chrousos, G.P.4
Charmandari, E.5
-
105
-
-
33745746815
-
Pharmacological strategies for overcoming multidrug resistance
-
Nobili S, Landini I, Giglioni B, Mini E, (2006). Pharmacological strategies for overcoming multidrug resistance. Curr Drug Targets 7: 861-879.
-
(2006)
Curr Drug Targets
, vol.7
, pp. 861-879
-
-
Nobili, S.1
Landini, I.2
Giglioni, B.3
Mini, E.4
-
106
-
-
33745153759
-
Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma
-
DOI 10.1378/chest.129.6.1478
-
O'Byrne PM, Pedersen S, Busse WW, Tan WC, Chen YZ, Ohlsson SV, et al,. (2006). Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma. Chest 129: 1478-1485. (Pubitemid 43894975)
-
(2006)
Chest
, vol.129
, Issue.6
, pp. 1478-1485
-
-
O'Byrne, P.M.1
Pedersen, S.2
Busse, W.W.3
Tan, W.C.4
Chen, Y.-Z.5
Ohlsson, S.V.6
Ullman, A.7
Lamm, C.J.8
Pauwels, R.A.9
-
107
-
-
0036392066
-
Quantitative analysis for human glucocorticoid receptor alpha/beta mRNA in IBD
-
Orii F, Ashida T, Nomura M, Maemoto A, Fujiki T, Ayabe T, et al,. (2002). Quantitative analysis for human glucocorticoid receptor alpha/beta mRNA in IBD. Biochem Biophys Res Commun 296: 1286-1294.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1286-1294
-
-
Orii, F.1
Ashida, T.2
Nomura, M.3
Maemoto, A.4
Fujiki, T.5
Ayabe, T.6
-
108
-
-
65649112534
-
Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2
-
Osoata G, Yamamura S, Ito M, Vuppusetty C, Adcock IM, Barnes PJ, et al,. (2009). Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2. Biochem Biophys Res Commun 384: 366-371.
-
(2009)
Biochem Biophys Res Commun
, vol.384
, pp. 366-371
-
-
Osoata, G.1
Yamamura, S.2
Ito, M.3
Vuppusetty, C.4
Adcock, I.M.5
Barnes, P.J.6
-
109
-
-
8844229534
-
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
-
DOI 10.1038/sj.gene.6364123
-
Potocnik U, Ferkolj I, Glavac D, Dean M, (2004). Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis. Genes Immun 5: 530-539. (Pubitemid 39529969)
-
(2004)
Genes and Immunity
, vol.5
, Issue.7
, pp. 530-539
-
-
Potocnik, U.1
Ferkolj, I.2
Glavac, D.3
Dean, M.4
-
110
-
-
34248575033
-
Alpha and beta glucocorticoid receptors: Relevance in airway diseases
-
DOI 10.1007/s11882-007-0005-3
-
Pujols L, Mullol J, Picado C, (2007). Alpha and beta glucocorticoid receptors: relevance in airway diseases. Curr Allergy Asthma Rep 7: 93-99. (Pubitemid 46744744)
-
(2007)
Current Allergy and Asthma Reports
, vol.7
, Issue.2
, pp. 93-99
-
-
Pujols, L.1
Mullol, J.2
Picado, C.3
-
111
-
-
34548660457
-
Global strategy for the diagnosis, management, and prevention of COPD - 2006 Update
-
Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, et al,. (2007). Global strategy for the diagnosis, management, and prevention of COPD-2006 Update. Am J Respir Crit Care Med 176: 532-555.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 532-555
-
-
Rabe, K.F.1
Hurd, S.2
Anzueto, A.3
Barnes, P.J.4
Buist, S.A.5
Calverley, P.6
-
112
-
-
26844433194
-
Antiinflammatory action of glucocorticoids - New mechanisms for old drugs
-
Rhen T, Cidlowski JA, (2005). Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 353: 1711-1723.
-
(2005)
N Engl J Med
, vol.353
, pp. 1711-1723
-
-
Rhen, T.1
Cidlowski, J.A.2
-
113
-
-
29744463898
-
Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1
-
DOI 10.1002/eji.200535413
-
Roger T, Chanson AL, Knaup-Reymond M, Calandra T, (2005). Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1. Eur J Immunol 35: 3405-3413. (Pubitemid 43025521)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.12
, pp. 3405-3413
-
-
Roger, T.1
Chanson, A.-L.2
Knaup-Reymond, M.3
Calandra, T.4
-
114
-
-
0032525889
-
Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF): Potential role in asthma
-
Rossi AG, Haslett C, Hirani N, Greening AP, Rahman I, Metz CN, et al,. (1998). Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma. J Clin Invest 101: 2869-2874. (Pubitemid 28294596)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.12
, pp. 2869-2874
-
-
Rossi, A.G.1
Haslett, C.2
Hirani, N.3
Greening, A.P.4
Rahman, I.5
Metz, C.N.6
Bucala, R.7
Donnelly, S.C.8
-
115
-
-
0037180086
-
2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
-
DOI 10.1016/S0140-6736(02)11319-5
-
Roth M, Johnson PR, Rudiger JJ, King GG, Ge Q, Burgess JK, et al,. (2002). Interaction between glucocorticoids and β2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet 360: 1293-1299. (Pubitemid 35284621)
-
(2002)
Lancet
, vol.360
, Issue.9342
, pp. 1293-1299
-
-
Roth, M.1
Johnson, P.R.A.2
Rudiger, J.J.3
King, G.G.4
Ge, Q.5
Burgess, J.K.6
Anderson, G.7
Tamm, M.8
Black, J.L.9
-
116
-
-
34547887674
-
Selective glucocorticoid receptor agonists (SEGRAs): Novel ligands with an improved therapeutic index
-
DOI 10.1016/j.mce.2007.05.014, PII S0303720707002134
-
Schacke H, Berger M, Rehwinkel H, Asadullah K, (2007). Selective glucocorticoid receptor agonists (SEGRAs): novel ligands with an improved therapeutic index. Mol Cell Endocrinol 275: 109-117. (Pubitemid 47259282)
-
(2007)
Molecular and Cellular Endocrinology
, vol.275
, Issue.1-2
, pp. 109-117
-
-
Schacke, H.1
Berger, M.2
Rehwinkel, H.3
Asadullah, K.4
-
117
-
-
0028079557
-
Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy
-
Sher ER, Leung YM, Surs W, Kam JC, Zieg G, Kamada AK, et al,. (1994). Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest 93: 33-39.
-
(1994)
J Clin Invest
, vol.93
, pp. 33-39
-
-
Sher, E.R.1
Leung, Y.M.2
Surs, W.3
Kam, J.C.4
Zieg, G.5
Kamada, A.K.6
-
118
-
-
33845218654
-
Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling
-
DOI 10.1128/MCB.00679-06
-
Smoak K, Cidlowski JA, (2006). Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling. Mol Cell Biol 26: 9126-9135. (Pubitemid 44851967)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.23
, pp. 9126-9135
-
-
Smoak, K.1
Cidlowski, J.A.2
-
119
-
-
0004815929
-
Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor β-isoform
-
Sousa AR, Lane SJ, Cidlowski JA, Staynov DZ, Lee TH, (2000). Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor beta-isoform. J Allergy Clin Immunol 105: 943-950. (Pubitemid 30324403)
-
(2000)
Journal of Allergy and Clinical Immunology
, vol.105
, Issue.5
, pp. 943-950
-
-
Sousa, A.R.1
Lane, S.J.2
Cidlowski, J.A.3
Staynov, D.Z.4
Lee, T.H.5
-
120
-
-
0030587138
-
A Novel Action of IL-13: Induction of Diminished Monocyte Glucocorticoid Receptor-Binding Affinity
-
Spahn JD, Szefler SJ, Surs W, Doherty DE, Nimmagadda SR, Leung DY, (1996). A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity. J Immunol 157: 2654-2659. (Pubitemid 126450482)
-
(1996)
Journal of Immunology
, vol.157
, Issue.6
, pp. 2654-2659
-
-
Spahn, J.D.1
Szefler, S.J.2
Surs, W.3
Doherty, D.E.4
Nimmagadda, S.R.5
Leung, D.Y.M.6
-
121
-
-
66749146095
-
Effect of theophylline plus beclometasone on lung function in smokers with asthma-A pilot study
-
Spears M, Donnelly I, Jolly L, Brannigan M, Ito K, McSharry C, et al,. (2009). Effect of theophylline plus beclometasone on lung function in smokers with asthma-a pilot study. Eur Respir J 33: 1010-1017.
-
(2009)
Eur Respir J
, vol.33
, pp. 1010-1017
-
-
Spears, M.1
Donnelly, I.2
Jolly, L.3
Brannigan, M.4
Ito, K.5
McSharry, C.6
-
122
-
-
69249124565
-
Inhaled corticosteroids in COPD: The case against
-
Suissa S, Barnes PJ, (2009). Inhaled corticosteroids in COPD: the case against. Eur Respir J 34: 13-16.
-
(2009)
Eur Respir J
, vol.34
, pp. 13-16
-
-
Suissa, S.1
Barnes, P.J.2
-
123
-
-
6344265739
-
Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase
-
DOI 10.1074/jbc.M406568200
-
Szatmary Z, Garabedian MJ, Vilcek J, (2004). Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase. J Biol Chem 279: 43708-43715. (Pubitemid 39390675)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.42
, pp. 43708-43715
-
-
Szatmary, Z.1
Garabedian, M.J.2
Vilcek, J.3
-
124
-
-
33845382332
-
Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells
-
DOI 10.1165/rcmb.2006-0073OC
-
Tao T, Lan J, Lukacs GL, Hache RJ, Kaplan F, (2006). Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells. Am J Respir Cell Mol Biol 35: 668-680. (Pubitemid 44901856)
-
(2006)
American Journal of Respiratory Cell and Molecular Biology
, vol.35
, Issue.6
, pp. 668-680
-
-
Tao, T.1
Lan, J.2
Lukacs, G.L.3
Hache, R.J.G.4
Kaplan, F.5
-
126
-
-
77958173826
-
Targeting phosphoinositide-3-kinase-Î with theophylline reverses corticosteroid insensitivity in COPD
-
To M, Ito K, Kizawa Y, Failla M, Ito M, Kusama T, et al,. (2010). Targeting phosphoinositide-3-kinase-Î with theophylline reverses corticosteroid insensitivity in COPD. Am J Respir Crit Care Med 182: 897-904.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 897-904
-
-
To, M.1
Ito, K.2
Kizawa, Y.3
Failla, M.4
Ito, M.5
Kusama, T.6
-
127
-
-
39549115677
-
Overcoming drug resistance induced by P-glycoprotein on lymphocytes in patients with refractory rheumatoid arthritis
-
DOI 10.1136/ard.2007.070821
-
Tsujimura S, Saito K, Nawata M, Nakayamada S, Tanaka Y, (2008). Overcoming drug resistance induced by P-glycoprotein on lymphocytes in patients with refractory rheumatoid arthritis. Ann Rheum Dis 67: 380-388. (Pubitemid 351281275)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.3
, pp. 380-388
-
-
Tsujimura, S.1
Saito, K.2
Nawata, M.3
Nakayamada, S.4
Tanaka, Y.5
-
128
-
-
24944482440
-
Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy
-
DOI 10.1164/rccm.200408-1041OC
-
Usmani OS, Ito K, Maneechotesuwan K, Ito M, Johnson M, Barnes PJ, et al,. (2005). Glucocorticoid receptor nuclear translocation in airway cells following inhaled combination therapy. Am J Respir Crit Care Med 172: 704-712. (Pubitemid 41324225)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.172
, Issue.6
, pp. 704-712
-
-
Usmani, O.S.1
Ito, K.2
Maneechotesuwan, K.3
Ito, M.4
Johnson, M.5
Barnes, P.J.6
Adcock, I.M.7
-
129
-
-
33745187366
-
Cytoskeletal and cell contact control of the glucocorticoid pathway
-
Vardimon L, Ben Dror I, Oren A, Polak P, (2006). Cytoskeletal and cell contact control of the glucocorticoid pathway. Mol Cell Endocrinol 252: 142-147.
-
(2006)
Mol Cell Endocrinol
, vol.252
, pp. 142-147
-
-
Vardimon, L.1
Ben Dror, I.2
Oren, A.3
Polak, P.4
-
130
-
-
33750521366
-
Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma
-
DOI 10.1016/j.jaci.2006.07.039, PII S0091674906015910
-
Vasavda N, Eichholtz T, Takahashi A, Affleck K, Matthews JG, Barnes PJ, et al,. (2006). Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma. J Allergy Clin Immunol 118: 1090-1096. (Pubitemid 44666984)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.118
, Issue.5
, pp. 1090-1096
-
-
Vasavda, N.1
Eichholtz, T.2
Takahashi, A.3
Affleck, K.4
Matthews, J.G.5
Barnes, P.J.6
Adcock, I.M.7
-
131
-
-
0035900780
-
Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids
-
Wallace AD, Cidlowski JA, (2001). Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids. J Biol Chem 276: 42714-42721.
-
(2001)
J Biol Chem
, vol.276
, pp. 42714-42721
-
-
Wallace, A.D.1
Cidlowski, J.A.2
-
132
-
-
0035810930
-
Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance
-
DOI 10.1073/pnas.121455098
-
Webster JC, Oakley RH, Jewell CM, Cidlowski JA, (2001). Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance. Proc Natl Acad Sci U S A 98: 6865-6870. (Pubitemid 32538308)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.12
, pp. 6865-6870
-
-
Webster, J.C.1
Oakley, R.H.2
Jewell, C.M.3
Cidlowski, J.A.4
-
133
-
-
34948900221
-
Steroid receptor phosphorylation: A key modulator of multiple receptor functions
-
DOI 10.1210/me.2007-0101
-
Weigel NL, Moore NL, (2007). Steroid receptor phosphorylation: a key modulator of multiple receptor functions. Mol Endocrinol 21: 2311-2319. (Pubitemid 47529347)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.10
, pp. 2311-2319
-
-
Weigel, N.L.1
Moore, N.L.2
-
134
-
-
31044447205
-
Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients
-
DOI 10.1172/JCI21759
-
Xystrakis E, Kusumakar S, Boswell S, Peek E, Urry Z, Richards DF, et al,. (2006). Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. J Clin Invest 116: 146-155. (Pubitemid 43121799)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 146-155
-
-
Xystrakis, E.1
Kusumakar, S.2
Boswell, S.3
Peek, E.4
Urry, Z.5
Richards, D.F.6
Adikibi, T.7
Pridgeon, C.8
Dallman, M.9
Loke, T.-K.10
Robinson, D.S.11
Barrat, F.J.12
O'Garra, A.13
Lavender, P.14
Lee, T.H.15
Corrigan, C.16
Hawrylowicz, C.M.17
-
135
-
-
34548400452
-
Inhaled corticosteroids for stable chronic obstructive pulmonary disease
-
Yang IA, Fong KM, Sim EH, Black PN, Lasserson TJ, (2007). Inhaled corticosteroids for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev CD002991.
-
(2007)
Cochrane Database Syst Rev
-
-
Yang, I.A.1
Fong, K.M.2
Sim, E.H.3
Black, P.N.4
Lasserson, T.J.5
|