SiRNA-mediated knock-down of NOX3: Therapy for hearing loss?

Cellular and Molecular Life Sciences

Volumn 69, Issue 14, 2012, Pages 2429-2434

  Rybak, Leonard P ^a   Mukherjea, Debashree ^a   Jajoo, Sarvesh ^a   Kaur, Tejbeer ^a   Ramkumar, Vickram ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cisplatin; Cochlea; Hearing loss; NOX3; SiRNA

Indexed keywords

CAPSAICIN; CISPLATIN; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; PARAQUAT; PROTEIN BCL 2; PROTEIN NOX3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; STAT1 PROTEIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

DRUG EFFECT; DRUG SAFETY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SILENCING; HEARING LOSS; HUMAN; INNER EAR; KIDNEY INJURY MOLECULE 1 GENE; MOLECULAR PATHOLOGY; NONHUMAN; NOX 3 GENE; OTOTOXICITY; PROTEIN EXPRESSION; REVIEW; TREATMENT DURATION; UPREGULATION;

CISPLATIN; EAR, INNER; HEARING LOSS; HUMANS; MEMBRANE PROTEINS; NADPH OXIDASE; PARAQUAT; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84864375987     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1016-3     Document Type: Review

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