TRPM2 Ca2+ permeable cation channels: From gene to biological function

Cell Calcium

Volumn 33, Issue 5-6, 2003, Pages 519-531

  Perraud, Anne Laure ^a   Schmitz, Carsten ^a   Scharenberg, Andrew M ^b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

ADP ribose; Enzymes; Multimers; NUDT9; Oxidant stress; TRPM channels

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; CALCIUM ION; CATION CHANNEL; GENE PRODUCT; HYDROLASE; MEMBRANE PROTEIN; TRANSIENT RECEPTOR POTENTIAL M2 PROTEIN; UNCLASSIFIED DRUG; CALCIUM; INORGANIC PYROPHOSPHATASE; ION CHANNEL; NUDT9; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CHROMOSOME 21; ENZYME ACTIVITY; GENE LOCATION; GENETIC TRANSCRIPTION; HUMAN; ION PERMEABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; AMINO ACID SEQUENCE; ANIMAL; CALCIUM SIGNALING; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; SEQUENCE HOMOLOGY;

ADENOSINE DIPHOSPHATE RIBOSE; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALCIUM SIGNALING; HUMANS; ION CHANNELS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PYROPHOSPHATASES; SEQUENCE HOMOLOGY, AMINO ACID; TRPM CATION CHANNELS;

EID: 0037636203     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4160(03)00057-5     Document Type: Review

References (21)

1. 2+ channel protein (TRPC7) highly expressed in brain, Genomics 54 (1998) 124-131.
2. A.L. Perraud, A. Fleig, C.A. Dunn, L.A. Bagley, P. Launay, C. Schmitz, A.J. Stokes, Q. Zhu, M.J. Bessman, R. Penner, J.P. Kinet, A.M. Scharenberg, ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology, Nature 411 (2001) 595-599.
3. 2+ influx system mediated by LTRPC2, Science 293 (2001) 1327-1330.
4. 2+-penneable channel activated by changes in redox status confers susceptibility to cell death, Mol. Cell 9 (2002) 163-173.
5. E. Wehage, J. Eisfeld, I. Heiner, E. Jungling, C. Zitt, A. Luckhoff, Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose, J. Biol. Chem. 277 (2002) 23150-23156.
6. M. Muenke, L.J. Bone, H.F. Mitchell, I. Hart, K. Walton, K. Hall-Johnson, E.F. Ippel, J. Dietz-Band, K. Kvaloy, C.M. Fan, et al., Physical mapping of the holoprosencephaly critical region in 21q22.3 exclusion of SIM2 as a candidate gene for holoprosencephaly, and mapping of SIM2 to a region of chromosome 21 important for Down syndrome, Am. J. Hum. Genet. 57 (1995) 1074-1079.
7. P.S. Herson, K.A. Dulock, M.L. Ashford, Characterization of a nicotinamide-adenine dinucleotide-dependent cation channel in the CRI-G1 rat insulinoma cell line, J. Physiol. 505 (Pt1) (1997) 65-76.
8. 2 in the rat insulin-secreting cell line CRI-G1, J. Physiol. 501 (Pt 1) (1997) 59-66.
9. M. Rechsteiner, D. Hillyard, B.M. Olivera, Turnover at nicotinamide adenine dinucleotide in cultures of human cells, J. Cell Physiol. 88 (1976) 207-217.
10. D. Hillyard, M. Rechsteiner, P. Manlapaz-Ramos, J.S. Imperial, L.J. Cruz, B.M. Olivera, The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2, J. Biol. Chem. 256 (1981) 8491-8497.
11. C. Richter, J. Schlegel, Mitochondrial calcium release induced by prooxidants, Toxicol. Lett. 67 (1993) 119-127.
12. L. Davidovic, M. Vodenicharov, E.B. Affar, G.G.. Poirier, Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism, Exp. Cell Res. 268 (2001) 7-13.
13. 2+-dependence of TRPM2 cation channel activation, J. Biol. Chem. (2003) in press.
14. J.M. Denu, Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases, Trends Biochem. Sci. 28 (2003) 41-48.
15. 2+ activated nonselective cation channel mediating cell membrane depolarization, Cell 109 (2002) 397-407.
16. A.G. McLennan, The MutT motif family of nucleotide phosphohydrolases in man and human pathogens (review), Int. J. Mol. Med. 4 (1999) 79-89.
17. M.J. Bessman, D.N. Frick, S.F. O'Handley, The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes, J. Biol. Chem. 271 (1996 ) 25059-25062.
18. D.D. McKemy, W.M. Neuhausser, D. Julius, Identification of a cold receptor reveals a general role for TRP channels in thermosensation, Nature 416 (2002) 52-58.
19. A.M. Peier, A. Moqrich, A.C. Hergarden, A.J. Reeve, D.A. Andersson, G.M. Story, T.J. Earley, I. Dragoni, P. McIntyre, S. Bevan, A. Patapoutian, A TRP channel that senses cold stimuli and menthol, Cell 108 (2002) 705-715.
20. M.J. Nadler, M.C. Hermosura, K. Inabe, A.L. Perraud, Q. Zhu, A.J. Stokes, I Kurosaki, J.R Kinet, R. Penner, A.M. Scharenberg, A. Fleig, LTRPC7 is a Mg-ATP-regulated divalent cation channel required for cell viability, Nature 411 (2001) 590-595.
21. A.L. Perraud, B. Shen, C.A. Dunn, K. Rippe, M.K. Smith, M.J. Bessman, B.L. Stoddard, A.M. Scharenberg, NUDT9, a member of the nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase, J. Biol. Chem. 278 (2003) 1794-1801.