A role for sensory nerves in the late asthmatic response

Thorax

Volumn 67, Issue 1, 2012, Pages 19-25

  Raemdonck, Kristof ^a,b   De Alba, Jorge ^a,b   Birrell, Mark A ^a,b   Grace, Megan ^a,b   Maher, Sarah A ^a,b   Irvin, Charles G ^c   Fozard, John R ^a,b   O'Byrne, Paul M ^d   Belvisi, Maria G ^a,b,e  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d ST JOSEPH S HOSPITAL   (Canada)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 [3 (TRIFLUOROMETHYL) 2 PYRIDINYL] N [5 (TRIFLUOROMETHYL) 2 PYRIDINYL] 1 PIPERAZINECARBOXAMIDE; BUDESONIDE; FORMOTEROL; HC 030031; KETAMINE; MEPYRAMINE; METHYSERGIDE; MONTELUKAST; OVALBUMIN; PROTEIN INHIBITOR; RUTHENIUM RED; TIOTROPIUM BROMIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; UNCLASSIFIED DRUG; XYLAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; LUNG FUNCTION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; RESPIRATORY DISTRESS; SENSORY NERVE; TREATMENT RESPONSE; WHEEZING;

EID: 84855204361     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2011-200365     Document Type: Article

References (53)

1. Lemanske RF Jr, Busse WW. 6. Asthma. J Allergy Clin Immunol 2003;111(2 Suppl):S502-19. (Pubitemid 36223289)
2. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31:143-78.
3. Sporik R, Holgate ST, Platts-Mills TA, et al. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med 1990;323:502-7. (Pubitemid 20260050)
4. Gauvreau GM, Watson RM, O'Byrne PM. Kinetics of allergen-induced airway eosinophilic cytokine production and airway inflammation. Am J Respir Crit Care Med 1999;160:640-7. (Pubitemid 29380685)
5. Cartier A, Thomson NC, Frith PA, et al. Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol 1982;70:170-7. (Pubitemid 12028763)
6. Diamant Z, Grootendorst DC, Veselic-Charvat M, et al. The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma. Clin Exp Allergy 1999;29:42-51. (Pubitemid 29067651)
7. Duong M, Gauvreau G, Watson R, et al. The effects of inhaled budesonide and formoterol in combination and alone when given directly after allergen challenge. J Allergy Clin Immunol 2007;119:322-7. (Pubitemid 46210078)
8. Boulet LP, Gauvreau GM, Boulay ME, et al. The allergen bronchoprovocation model. An important tool for the investigation of new asthma anti-inflammatory therapies. Allergy 2007;62:1101-10.
9. O'Byrne PM, Gauvreau GM, Brannan JD. Provoked models of asthma: what have we learnt? Clin Exp Allergy 2009;39:181-92.
10. Cockcroft DW, Murdock KY. Comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine. J Allergy Clin Immunol 1987;79:734-40. (Pubitemid 17074292)
11. Kidney JC, Boulet LP, Hargreave FE, et al. Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model. J Allergy Clin Immunol 1997;100:65-70. (Pubitemid 27328533)
12. Inman MD, Watson RM, Rerecich T, et al. Dose-dependent effects of inhaled mometasone furoate on airway function and inflammation after allergen inhalation challenge. Am J Respir Crit Care Med 2001;164:569-74. (Pubitemid 32801658)
13. Leigh R, Vethanayagam D, Yoshida M, et al. Effects of montelukast and budesonide on airway responses and airway inflammation in asthma. Am J Respir Crit Care Med 2002;166:1212-17. (Pubitemid 35222598)
14. Fahy JV, Fleming HE, Wong HH, et al. The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects. Am J Respir Crit Care Med 1997;155:1828-34. (Pubitemid 27256105)
15. Twentyman OP, Holgate ST. Reversibility of the allergen-provoked late asthmatic response by an inhaled beta 2-adrenoceptor agonist. Clin Exp Allergy 1994;24:245-9. (Pubitemid 24214502)
16. Larsen GL, Wilson MC, Clark RA, et al. The inflammatory reaction in the airways in an animal model of the late asthmatic response. Fed Proc 1987;46:105-12. (Pubitemid 17056329)
17. Nabe T, Zindl CL, Jung YW, et al. Induction of a late asthmatic response associated with airway inflammation in mice. Eur J Pharmacol 2005;521:144-55. (Pubitemid 41427802)
18. Moon H, Choi HH, Lee JY, et al. Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. Arch Pharm Res 2008;31:771-8.
19. Yamada N, Kadowaki S, Umezu K. Development of an animal model of late asthmatic response in guinea pigs and effects of anti-asthmatic drugs. Prostaglandins 1992;43:507-21.
20. Eidelman DH, Bellofiore S, Martin JG. Late airway responses to antigen challenge in sensitized inbred rats. Am Rev Respir Dis 1988;137:1033-7.
21. Cieslewicz G, Tomkinson A, Adler A, et al. The late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltration. J Clin Invest 1999;104:301-8.
22. Birrell MA, Hardaker E, Wong S, et al. Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma. Am J Respir Crit Care Med 2005;172:962-71. (Pubitemid 41476532)
23. Xu L, Olivenstein R, Martin JG, et al. Inhaled budesonide inhibits OVA-induced airway narrowing, inflammation, and cys-LT synthesis in BN rats. J Appl Physiol 2000;89:1852-8.
24. Hele DJ, Birrell MA, Webber SE, et al. Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. Br J Pharmacol 2001;132:481-8. (Pubitemid 32142362)
25. Franco-Cereceda A, Lou YP, Lundberg JM. Ruthenium-red inhibits CGRP release by capsaicin and resiniferatoxin but not by ouabain, bradykinin or nicotine in guinea-pig heart: correlation with effects on cardiac contractility. Br J Pharmacol 199;104:305-10.
26. Tapia R, Velasco I. Ruthenium red as a tool to study calcium channels, neuronal death and the function of neural pathways. Neurochem Int 1997;30:137-47. (Pubitemid 27029172)
27. Bhattacharya A, Scott BP, Nasser N, et al. Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs. J Pharmacol Exp Ther 2007;323:665-74. (Pubitemid 350005126)
28. McNamara CR, Mandel-Brehm J, Bautista DM, et al. TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA 2007;104:13525-30. (Pubitemid 47293978)
29. Henry PJ, Goldie RG. Beta 1-adrenoceptors mediate smooth muscle relaxation in mouse isolated trachea. Br J Pharmacol 1990;99:131-5. (Pubitemid 20033798)
30. Caceres AI, Brackmann M, Elia MD, et al. A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci USA 2009;106:9099-104.
31. Lalloo UG, Fox AJ, Belvisi MG, et al. Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. J Appl Physiol 1995;79:1082-7.
32. Birrell MA, Belvisi MG, Grace M, et al. TRPA1 agonists evoke coughing in guinea pig and human volunteers. Am J Respir Crit Care Med 2009;180:1042-7.
33. Kuo YL, Lai CJ. Ovalbumin sensitizes vagal pulmonary C-fiber afferents in Brown Norway rats. J Appl Physiol 2008;105:611-20.
34. McLeod RL, Fernandez X, Correll CC, et al. TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs. Cough 2006;2:10.
35. Toward TJ, Broadley KJ. Early and late bronchoconstrictions, airway hyper-reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram. Clin Exp Allergy 2004;34:91-102. (Pubitemid 38183686)
36. Fabbri LM, Hendrick DJ, Diem JE. Effect of atropine on the bronchial response of asthmatic subjects to the inhalation of ultrasonically nebulized distilled water. J Allergy Clin Immunol 1983;71:468-72. (Pubitemid 13083845)
37. Sheppard D, Epstein J, Holtzman MJ, et al. Dose-dependent inhibition of cold air-induced bronchoconstriction by atropine. J Appl Physiol 1982;53:169-74. (Pubitemid 12092426)
38. Deal EC Jr, McFadden ER Jr, Ingram RH Jr, et al. Effects of atropine on potentiation of exercise-induced bronchospasm by cold air. J Appl Physiol 1978;45:238-43.
39. Pennock BE, Cox CP, Rogers RM, et al. A noninvasive technique for measurement of changes in specific airway resistance. J Appl Physiol 1979;46:399-406. (Pubitemid 9158788)
40. Hamelmann E, Schwarze J, Takeda K, et al. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 1997;156:766-75. (Pubitemid 27396413)
41. Dohi M, Tsukamoto S, Nagahori T, et al. Noninvasive system for evaluating the allergen-specific airway response in a murine model of asthma. Lab Invest 1999;79:1559-71. (Pubitemid 30013921)
42. Liu S, Chihara K, Maeyama K. The contribution of mast cells to the late-phase of allergic asthma in rats. Inflamm Res 2005;54:221-8. (Pubitemid 40880136)
43. Bates J, Irvin C, Brusasco V, et al. The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol 2004;31:373-4. (Pubitemid 39180309)
44. Bautista DM, Jordt SE, Nikai T, et al. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 2006;124:1269-82.
45. Taylor-Clark TE, McAlexander MA, Nassenstein C, et al. Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autocoid 4-oxononenal. J Physiol 2008;586:3447-59. (Pubitemid 352003876)
46. Maher SA, Birrell MA, Belvisi MG. Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy. Am J Respir Crit Care Med 2009;180:923-8.
47. Montuschi P, Kharitonov SA, Ciabattoni G, et al. Exhaled leukotrienes and prostaglandins in COPD. Thorax 2003;58:585-8. (Pubitemid 36808128)
48. 2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia. J Allergy Clin Immunol 2003;112:709-16.
49. Coyle AJ, Ackerman SJ, Burch R, et al. Human eosinophil-granule major basic protein and synthetic polycations induce airway hyperresponsiveness in vivo dependent on bradykinin generation. J Clin Invest 1995;95:1735-40.
50. Bandell M, Story GM, Hwang SW, et al. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 2004;4:849-57. (Pubitemid 38429729)
51. Fabbri LM, Chiesura-Corona P, Dal Vecchio L, et al. Prednisone inhibits late asthmatic reactions and the associated increase in airway responsiveness induced by toluene-diisocyanate in sensitized subjects. Am Rev Respir Dis 1985;132:1010-14. (Pubitemid 16226299)
52. Taylor-Clark TE, Kiros F, Carr MJ, et al. Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation. Am J Respir Cell Mol Biol 2009;40:756-62.
53. Peters SP, Kunselman SJ, Icitovic N, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med 2010;363:1715-26.