TRPA1 antagonists as potential analgesic drugs

Pharmacology and Therapeutics

Volumn 133, Issue 2, 2012, Pages 189-204

  Andrade, E L ^a   Meotti, F C ^b   Calixto, J B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Analgesia; Cold; Hyperalgesia; Nociception; TRPA1; TRPV1

Indexed keywords

[4 BROMO N [2,2,2 TRICHLORO 1 [(4 CHLOROPHENYL)]; ALLYL ISOTHIOCYANATE; AMG 2504; AMG 5445; AMG 7160; AMG 9090; BRADYKININ; CALCIUM; CAMPHOR; CAPSAICIN; CARBON DIOXIDE; CHLORPROMAZINE; CLIOQUINOL; CLOTRIMAZOLE; CMP 1; CMP 2; CMP 3; G PROTEIN COUPLED RECEPTOR; HC 030031; ISOFLURANE; N (1,4 BENZODIOXAN 6 YL) 3 (4 TERT BUTYLPHENYL)ACRYLAMIDE; N [2,2,2 TRICHLORO 1 [[4 CHLOROPHENYL]SULFANYL]ETHYL] BENZAMIDE]; OLIGODEOXYNUCLEOTIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANALGESIC ACTIVITY; ATOPIC DERMATITIS; BIOSENSOR; BLOOD PRESSURE REGULATION; COLD SENSITIVITY; EXPERIMENTAL MODEL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HYPERALGESIA; INFLAMMATION; MECHANOTRANSDUCTION; NERVE INJURY; NEUROPATHIC PAIN; NOCICEPTIVE PAIN; NOCICEPTIVE RECEPTOR; NOCICEPTIVE STIMULATION; NONHUMAN; OXIDATIVE STRESS; PAIN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVIEW; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL; STIMULUS; TISSUE INJURY;

ANALGESICS; ANIMALS; CALCIUM CHANNELS; CHRONIC PAIN; HUMANS; NERVE TISSUE PROTEINS; SENSORY RECEPTOR CELLS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPC CATION CHANNELS;

EID: 84856409044     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2011.10.008     Document Type: Review

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