Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material

Molecular Pharmacology

Volumn 81, Issue 3, 2012, Pages 411-419

  Deering Rice, Cassandra E ^a   Johansen, Mark E ^a   Roberts, Jessica K ^a   Thomas, Karen C ^a   Romero, Erin G ^a   Lee, Jeewoo ^b   Yost, Garold S ^a   Veranth, John M ^a   Reilly, Christopher A ^a  

^a UNIVERSITY OF UTAH   (United States)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; SILICON DIOXIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 8; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2; VANILLOID RECEPTOR 3; VANILLOID RECEPTOR 4;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; EXHAUST GAS; FLY ASH; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG PARENCHYMA; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SENSORY NERVE CELL;

BASE SEQUENCE; CELL LINE, TRANSFORMED; COAL ASH; DNA PRIMERS; GENE EXPRESSION PROFILING; HUMANS; LUNG; POLYMERASE CHAIN REACTION; TRPV CATION CHANNELS;

EID: 84863143271     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.076067     Document Type: Article

References (51)

1. Agopyan N, Bhatti T, Yu S, and Simon SA (2003a) Vanilloid receptor activation by 2- and 10-micron particles induces responses leading to apoptosis in human airway epithelial cells. Toxicol Appl Pharmacol 192:21-35. (Pubitemid 37205115)
2. Agopyan N, Head J, Yu S, and Simon SA (2004) TRPV1 receptors mediate particulate matter-induced apoptosis. Am J Physiol Lung Cell Mol Physiol 286:L563-L572. (Pubitemid 38233628)
3. Agopyan N, Li L, Yu S, and Simon SA (2003b) Negatively charged 2- and 10-microm particles activate vanilloid receptors, increase cAMP, and induce cytokine release. Toxicol Appl Pharmacol 186:63-76. (Pubitemid 36298616)
4. Ahern GP, Brooks IM, Miyares RL, and Wang XB (2005) Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling. J Neurosci 25:5109-5116. (Pubitemid 40726964)
5. Bernstein JA, Alexis N, Barnes C, Bernstein IL, Bernstein JA, Nel A, Peden D, Diaz-Sanchez D, Tarlo SM, and Williams PB (2004) Health effects of air pollution. J Allergy Clin Immunol 114:1116-1123. (Pubitemid 39469153)
6. Bessac BF and Jordt SE (2008) Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. Physiology (Bethesda) 23:360-370.
7. Bohlen CJ, Priel A, Zhou S, King D, Siemens J, and Julius D (2010) A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain. Cell 141:834-845.
8. Cao X, Xu X, Cui W, and Xi Z (2001) Development and certification of a coal fly ash certified reference material for selected polycyclic aromatic hydrocarbons. Fresenius J Anal Chem 370:1035-1040. (Pubitemid 33753005)
9. Chow JC, Watson JG, Mauderly JL, Costa DL, Wyzga RE, Vedal S, Hidy GM, Altshuler SL, Marrack D, Heuss JM, et al. (2006) Health effects of fine particulate air pollution: lines that connect. J Air Waste Manag Assoc 56:1368-1380. (Pubitemid 46063428)
10. Costa SK, Teles AM, Kumagai Y, Brain SD, Teixeira SA, Varriano AA, Barreto MA, de Lima WT, Antunes E, Muscará MN, et al. (2010) Involvement of sensory nerves and TRPV1 receptors in the rat airway inflammatory response to two environment pollutants: diesel exhaust particles (DEP) and 1,2-naphthoquinone (1,2-NQ). Arch Toxicol 84:109-117.
11. Deering-Rice CE, Romero EG, Shapiro D, Hughen RW, Light AR, Yost GS, Veranth JM, and Reilly CA (2011) Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP. Chem Res Toxicol 24:950-959.
12. Ernst H, Rittinghausen S, Bartsch W, Creutzenberg O, Dasenbrock C, Görlitz BD, Hecht M, Kairies U, Muhle H, Müller M, et al. (2002) Pulmonary inflammation in rats after intratracheal instillation of quartz, amorphous SiO2, carbon black, and coal dust and the influence of poly-2-vinylpyridine-N-oxide (PVNO). Exp Toxicol Pathol 54:109-126.
13. Fernández-Ballester G and Ferrer-Montiel A (2008) Molecular modeling of the full-length human TRPV1 channel in closed and desensitized states. J Membr Biol 223:161-172.
14. Ghelfi E, Rhoden CR, Wellenius GA, Lawrence J, and Gonzalez-Flecha B (2008) Cardiac oxidative stress and electrophysiological changes in rats exposed to concentrated ambient particles are mediated by TRP-dependent pulmonary reflexes. Toxicol Sci 102:328-336. (Pubitemid 351404903)
15. Gilmour MI, O'Connor S, Dick CA, Miller CA, and Linak WP (2004) Differential pulmonary inflammation and in vitro cytotoxicity of size-fractionated fly ash particles from pulverized coal combustion. J Air Waste Manag Assoc 54:286-295. (Pubitemid 38296102)
16. Glinianaia SV, Rankin J, Bell R, Pless-Mulloli T, and Howel D (2004) Particulate air pollution and fetal health: a systematic review of the epidemiologic evidence. Epidemiology 15:36-45. (Pubitemid 40416995)
17. Inoue R, Jian Z, and Kawarabayashi Y (2009) Mechanosensitive TRP channels in cardiovascular pathophysiology. Pharmacol Ther 123:371-385.
18. Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
19. Jia Y, McLeod RL, and Hey JA (2005) TRPV1 receptor: a target for the treatment of pain, cough, airway disease and urinary incontinence. Drug News Perspect 18: 165-171. (Pubitemid 40704837)
20. Jin Y, Kim DK, Khil LY, Oh U, Kim J, and Kwak J (2004) Thimerosal decreases TRPV1 activity by oxidation of extracellular sulfhydryl residues. Neurosci Lett 369:250-255. (Pubitemid 39298918)
21. Johansen ME, Reilly CA, and Yost GS (2006) TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells. Toxicol Sci 89:278-286. (Pubitemid 43013776)
22. Jordt SE and Julius D (2002) Molecular basis for species-specific sensitivity to "hot"chili peppers. Cell 108:421-430.
23. Jordt SE, Tominaga M, and Julius D (2000) Acid potentiation of the capsaicin receptor determined by a key extracellular site. Proc Natl Acad Sci USA 97:8134-8139. (Pubitemid 30460785)
24. Kobayashi K, Fukuoka T, Obata K, Yamanaka H, Dai Y, Tokunaga A, and Noguchi K (2005) Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors. J Comp Neurol 493:596-606. (Pubitemid 41780630)
25. Li J, Kanju P, Patterson M, Chew WL, Cho SH, Gilmour I, Oliver T, Yasuda R, Ghio A, Simon SA, et al. (2011) TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environ Health Perspect 119:784-793.
26. Lighty JS, Veranth JM, and Sarofim AF (2000) Combustion aerosols: factors governing their size and composition and implications to human health. J Air Waste Manag Assoc 50:1565-1618; discussion 1619-1622.
27. Lin Z, Reilly CA, Antemano R, Hughen RW, Marett L, Concepcion GP, Haygood MG, Olivera BM, Light A, and Schmidt EW (2011) Nobilamides A-H, Long-Acting Transient Receptor Potential Vanilloid-1 (TRPV1) Antagonists from Mollusk-Associated Bacteria. J Med Chem 54:3746-3755.
28. Ogugbuaja VO, Onyeyili PA, and Moses EA (2001) Study of effects on haematological parameters of rabbits intratracheally exposed to coal fly ash. J Environ Sci Health A Tox Hazard Subst Environ Eng 36:1411-1418.
29. Oortgiesen M, Veronesi B, Eichenbaum G, Kiser PF, and Simon SA (2000) Residual oil fly ash and charged polymers activate epithelial cells and nociceptive sensory neurons. Am J Physiol Lung Cell Mol Physiol 278:L683-L695. (Pubitemid 30220029)
30. Pope CA, 3rd, Renlund DG, Kfoury AG, May HT, and Horne BD (2008) Relation of heart failure hospitalization to exposure to fine particulate air pollution. Am J Cardiol 102:1230-1234.
31. Reilly CA (2010) Neurogenic inflammation: the role of TRP channels in the lung, in Comprehensive Toxicology 2nd ed (McQueen CA ed), Elsevier, Amsterdam.
32. Reilly CA, Johansen ME, Lanza DL, Lee J, Lim JO, and Yost GS (2005) Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells. J Biochem Mol Toxicol 19:266-275.
33. Reilly CA, Taylor JL, Lanza DL, Carr BA, Crouch DJ, and Yost GS (2003) Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors. Toxicol Sci 73:170-181. (Pubitemid 36609099)
34. Sabnis AS, Shadid M, Yost GS, and Reilly CA (2008) Human lung epithelial cells express a functional cold-sensing TRPM8 variant. Am J Respir Cell Mol Biol 39:466-474.
35. Smith KR, Veranth JM, Kodavanti UP, Aust AE, and Pinkerton KE (2006) Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles. Toxicol Sci 93:390-399. (Pubitemid 44400457)
36. Takano H, Yanagisawa R, Ichinose T, Sadakane K, Inoue K, Yoshida S, Takeda K, Yoshino S, Yoshikawa T, and Morita M (2002a) Lung expression of cytochrome P450 1A1 as a possible biomarker of exposure to diesel exhaust particles. Arch Toxicol 76:146-151. (Pubitemid 34328048)
37. Takano H, Yanagisawa R, Ichinose T, Sadakane K, Yoshino S, Yoshikawa T, and Morita M (2002b) Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and intercellular adhesion molecule-1. Am J Respir Crit Care Med 165:1329-1335. (Pubitemid 34461749)
38. Thomas KC, Roberts JK, Deering-Rice CE, Romero EG, Dull RO, Lee J, Yost GS and Reilly CA (2011) Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. Am J Physiol Lung Cell Mol Physiol. http://dx.doi.org/10.1152/ajplung.00231.2011.
39. Thomas KC, Sabnis AS, Johansen ME, Lanza DL, Moos PJ, Yost GS, and Reilly CA (2007) Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. J Pharmacol Exp Ther 321:830-838. (Pubitemid 46762717)
40. Veranth JM, Cutler NS, Kaser EG, Reilly CA, and Yost GS (2008) Effects of cell type and culture media on Interleukin-6 secretion in response to environmental particles. Toxicol In Vitro 22:498-509.
41. Veranth JM, Moss TA, Chow JC, Labban R, Nichols WK, Walton JC, Watson JG, and Yost GS (2006) Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter. Environ Health Perspect 114:341-349. (Pubitemid 43338257)
42. Veranth JM, Reilly CA, Veranth MM, Moss TA, Langelier CR, Lanza DL, and Yost GS (2004) Inflammatory cytokines and cell death in BEAS-2B lung cells treated with soil dust, lipopolysaccharide, and surface-modified particles. Toxicol Sci 82: 88-96. (Pubitemid 39485323)
43. Veronesi B, Carter JD, Devlin RB, Simon SA, and Oortgiesen M (1999a) Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line. Neuropeptides 33:447-456. (Pubitemid 30110874)
44. Veronesi B, de Haar C, Lee L, and Oortgiesen M (2002) The surface charge of visible particulate matter predicts biological activation in human bronchial epithelial cells. Toxicol Appl Pharmacol 178:144-154. (Pubitemid 34214663)
45. Veronesi B, Oortgiesen M, Carter JD, and Devlin RB (1999b) Particulate matter initiates inflammatory cytokine release by activation of capsaicin and acid receptors in a human bronchial epithelial cell line. Toxicol Appl Pharmacol 154:106-115. (Pubitemid 29042605)
46. Veronesi B, Wei G, Zeng JQ, and Oortgiesen M (2003) Electrostatic charge activates inflammatory vanilloid (VR1) receptors. Neurotoxicology 24:463-473. (Pubitemid 36705895)
47. Ward DJ and Ayres JG (2004) Particulate air pollution and panel studies in children: a systematic review. Occup Environ Med 61:e13.
48. Wirkner K, Hognestad H, Jahnel R, Hucho F, and Illes P (2005) Characterization of rat transient receptor potential vanilloid 1 receptors lacking the N-glycosylation site N604. Neuroreport 16:997-1001. (Pubitemid 40904754)
49. Wong SS, Sun NN, Keith I, Kweon CB, Foster DE, Schauer JJ, and Witten ML (2003) Tachykinin substance P signaling involved in diesel exhaust-induced bronchopulmonary neurogenic inflammation in rats. Arch Toxicol 77:638-650. (Pubitemid 37491688)
50. Yang F, Cui Y, Wang K, and Zheng J (2010) Thermosensitive TRP channel pore turret is part of the temperature activation pathway. Proc Natl Acad Sci USA 107:7083-7088.
51. Yokota S, Ohara N, and Kobayashi T (2008) The effects of organic extract of diesel exhaust particles on ischemia/reperfusion-related arrhythmia and on pulmonary inflammation. J Toxicol Sci 33:1-10. (Pubitemid 351340758)