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Volumn 12, Issue 10, 2009, Pages 1293-1299

Nicotine activates the chemosensory cation channel TRPA1

Author keywords

[No Author keywords available]

Indexed keywords

HEXAMETHONIUM; MECAMYLAMINE; NICOTINE; NICOTINIC RECEPTOR; TRANSIENT RECEPTOR POTENTIAL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG;

EID: 70349559585     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn.2379     Document Type: Article
Times cited : (215)

References (50)
  • 2
    • 30944463237 scopus 로고    scopus 로고
    • The infuence of mecamylamine on trigeminal and olfactory chemoreception of nicotine
    • Thuerauf, N. et al. The infuence of mecamylamine on trigeminal and olfactory chemoreception of nicotine. Neuropsychopharmacology 31, 450-461 (2006).
    • (2006) Neuropsychopharmacology , vol.31 , pp. 450-461
    • Thuerauf, N.1
  • 4
    • 40749147526 scopus 로고    scopus 로고
    • Update on pharmacologic options for smoking cessation treatment
    • Nides, M. Update on pharmacologic options for smoking cessation treatment. Am. J. Med. 121, S20-S31 (2008).
    • (2008) Am. J. Med. , vol.121
    • Nides, M.1
  • 5
    • 0033610278 scopus 로고    scopus 로고
    • Randomized comparative trial of nicotine polacrilex, a transdermal patch, nasal spray and an inhaler
    • Hajek, P. et al. Randomized comparative trial of nicotine polacrilex, a transdermal patch, nasal spray and an inhaler. Arch. Intern. Med. 159, 2033-2038 (1999).
    • (1999) Arch. Intern. Med. , vol.159 , pp. 2033-2038
    • Hajek, P.1
  • 6
    • 0344874607 scopus 로고    scopus 로고
    • Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: A potential basis for the pro-infammatory effects of nicotine
    • Dussor, G.O. et al. Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: a potential basis for the pro-infammatory effects of nicotine. Eur. J. Neurosci. 18, 2515-2526 (2003).
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2515-2526
    • Dussor, G.O.1
  • 7
    • 0142090716 scopus 로고    scopus 로고
    • Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation
    • Simons, C.T., Sudo, S., Sudo, M. & Carstens, E. Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation. Brain Res. 991, 249-253 (2003).
    • (2003) Brain Res. , vol.991 , pp. 249-253
    • Simons, C.T.1    Sudo, S.2    Sudo, M.3    Carstens, E.4
  • 8
    • 56049109544 scopus 로고    scopus 로고
    • Cough sensors. IV. Nicotinic membrane receptors on cough sensors
    • Lee, L.Y. & Gu, Q. Cough sensors. IV. Nicotinic membrane receptors on cough sensors. Handb. Exp. Pharmacol. 187, 77-98 (2009).
    • (2009) Handb. Exp. Pharmacol. , vol.187 , pp. 77-98
    • Lee, L.Y.1    Gu, Q.2
  • 9
    • 44549087188 scopus 로고    scopus 로고
    • Neuronal TRP channels: Thermometers, pathfnders and lifesavers
    • Talavera, K., Nilius, B. & Voets, T. Neuronal TRP channels: thermometers, pathfnders and lifesavers. Trends Neurosci. 31, 287-295 (2008).
    • (2008) Trends Neurosci. , vol.31 , pp. 287-295
    • Talavera, K.1    Nilius, B.2    Voets, T.3
  • 12
    • 1542615229 scopus 로고    scopus 로고
    • Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors
    • Liu, L. et al. Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors. J. Neurophysiol. 91, 1482-1491 (2004).
    • (2004) J. Neurophysiol. , vol.91 , pp. 1482-1491
    • Liu, L.1
  • 13
    • 19444381231 scopus 로고    scopus 로고
    • 2+ permeability of nicotinic acetylcholine receptors from rat dorsal root ganglion neurones
    • Fucile, S., Sucapane, A. & Eusebi, F. Ca2+ permeability of nicotinic acetylcholine receptors from rat dorsal root ganglion neurones. J. Physiol. (Lond.) 565, 219-228 (2005).
    • (2005) J. Physiol. (Lond.) , vol.565 , pp. 219-228
    • Fucile, S.1    Sucapane, A.2    Eusebi, F.3
  • 14
    • 57749111494 scopus 로고    scopus 로고
    • Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and refex control
    • Bessac, B.F. & Jordt, S.E. Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and refex control. Physiology (Bethesda) 23, 360-370 (2008).
    • (2008) Physiology (Bethesda) , vol.23 , pp. 360-370
    • Bessac, B.F.1    Jordt, S.E.2
  • 15
    • 0345616438 scopus 로고    scopus 로고
    • ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
    • Story, G.M. et al. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112, 819-829 (2003).
    • (2003) Cell , vol.112 , pp. 819-829
    • Story, G.M.1
  • 16
    • 59049096524 scopus 로고    scopus 로고
    • TRPA1 acts as a cold sensor in vitro and in vivo
    • Karashima, Y. et al. TRPA1 acts as a cold sensor in vitro and in vivo. Proc. Natl. Acad. Sci. USA 106, 1273-1278 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 1273-1278
    • Karashima, Y.1
  • 17
    • 1642430679 scopus 로고    scopus 로고
    • Mustard oils and cannabinoids excite sensory nerve fbres through the TRP channel ANKTM1
    • Jordt, S.E. et al. Mustard oils and cannabinoids excite sensory nerve fbres through the TRP channel ANKTM1. Nature 427, 260-265 (2004).
    • (2004) Nature , vol.427 , pp. 260-265
    • Jordt, S.E.1
  • 18
    • 1842475312 scopus 로고    scopus 로고
    • Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
    • Bandell, M. et al. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41, 849-857 (2004).
    • (2004) Neuron , vol.41 , pp. 849-857
    • Bandell, M.1
  • 19
    • 46749091281 scopus 로고    scopus 로고
    • Cigarette smoke-induced neurogenic infammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents
    • Andrè, E. et al. Cigarette smoke-induced neurogenic infammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J. Clin. Invest. 118, 2574-2582 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 2574-2582
    • Andrè, E.1
  • 20
    • 33646045075 scopus 로고    scopus 로고
    • TRPA1 mediates the infammatory actions of environmental irritants and proalgesic agents
    • Bautista, D.M. et al. TRPA1 mediates the infammatory actions of environmental irritants and proalgesic agents. Cell 124, 1269-1282 (2006).
    • (2006) Cell , vol.124 , pp. 1269-1282
    • Bautista, D.M.1
  • 21
    • 33646061333 scopus 로고    scopus 로고
    • TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction
    • Kwan, K.Y. et al. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 50, 277-289 (2006).
    • (2006) Neuron , vol.50 , pp. 277-289
    • Kwan, K.Y.1
  • 22
    • 33746716158 scopus 로고    scopus 로고
    • More than cool: Promiscuous relationships of menthol and other sensory compounds
    • MacPherson, L.J. et al. More than cool: promiscuous relationships of menthol and other sensory compounds. Mol. Cell. Neurosci. 32, 335-343 (2006).
    • (2006) Mol. Cell. Neurosci. , vol.32 , pp. 335-343
    • MacPherson, L.J.1
  • 23
    • 34548610605 scopus 로고    scopus 로고
    • Bimodal action of menthol on the transient receptor potential channel TRPA1
    • Karashima, Y. et al. Bimodal action of menthol on the transient receptor potential channel TRPA1. J. Neurosci. 27, 9874-9884 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 9874-9884
    • Karashima, Y.1
  • 24
    • 55749087512 scopus 로고    scopus 로고
    • Identifcation of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels
    • Xiao, B. et al. Identifcation of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels. J. Neurosci. 28, 9640-9651 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 9640-9651
    • Xiao, B.1
  • 25
    • 38549095070 scopus 로고    scopus 로고
    • Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole
    • Meseguer, V. et al. Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole. J. Neurosci. 28, 576-586 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 576-586
    • Meseguer, V.1
  • 28
    • 33846692923 scopus 로고    scopus 로고
    • Noxious compounds activate TRPA1 ion channels through covalent modifcation of cysteines
    • Macpherson, L.J. et al. Noxious compounds activate TRPA1 ion channels through covalent modifcation of cysteines. Nature 445, 541-545 (2007).
    • (2007) Nature , vol.445 , pp. 541-545
    • MacPherson, L.J.1
  • 30
    • 34250379970 scopus 로고    scopus 로고
    • Transient receptor potential channel A1 is directly gated by calcium ions
    • Doerner, J.F., Gisselmann, G., Hatt, H. & Wetzel, C.H. Transient receptor potential channel A1 is directly gated by calcium ions. J. Biol. Chem. 282, 13180-13189 (2007).
    • (2007) J. Biol. Chem. , vol.282 , pp. 13180-13189
    • Doerner, J.F.1    Gisselmann, G.2    Hatt, H.3    Wetzel, C.H.4
  • 31
    • 0031813123 scopus 로고    scopus 로고
    • Activation of neurons in rat trigeminal subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa
    • Carstens, E., Kuenzler, N. & Handwerker, H.O. Activation of neurons in rat trigeminal subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa. J. Neurophysiol. 80, 465-492 (1998).
    • (1998) J. Neurophysiol. , vol.80 , pp. 465-492
    • Carstens, E.1    Kuenzler, N.2    Handwerker, H.O.3
  • 32
    • 33749538094 scopus 로고
    • Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract
    • Simons, C.T., Boucher, Y., Carstens, M.I. & Carstens, E. Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract. J. Neurophysiol. 96, 1877-1886 (2006).
    • (1877) J Neurophysiol. , vol.96 , pp. 2006
    • Simons, C.T.1    Boucher, Y.2    Carstens, M.I.3    Carstens, E.4
  • 33
    • 0035037736 scopus 로고    scopus 로고
    • Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes
    • Papke, R.L., Sanberg, P.R. & Shytle, R.D. Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes. J. Pharmacol. Exp. Ther. 297, 646-656 (2001).
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 646-656
    • Papke, R.L.1    Sanberg, P.R.2    Shytle, R.D.3
  • 34
    • 25644433563 scopus 로고    scopus 로고
    • Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism
    • Xu, H., Blair, N.T. & Clapham, D.E. Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J. Neurosci. 25, 8924-8937 (2005).
    • (2005) J. Neurosci. , vol.25 , pp. 8924-8937
    • Xu, H.1    Blair, N.T.2    Clapham, D.E.3
  • 35
    • 0029770120 scopus 로고    scopus 로고
    • Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons
    • Liu, L. & Simon, S.A. Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons. Am. J. Physiol. 270, C1807-C1814 (1996).
    • (1996) Am. J. Physiol. , vol.270
    • Liu, L.1    Simon, S.A.2
  • 36
    • 3543104904 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat
    • Haberberger, R.V. et al. Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat. Auton. Neurosci. 113, 32-42 (2004).
    • (2004) Auton. Neurosci. , vol.113 , pp. 32-42
    • Haberberger, R.V.1
  • 37
    • 33746743025 scopus 로고    scopus 로고
    • Refexes from the lungs and airways: Historical perspective
    • Widdicombe, J. Refexes from the lungs and airways: historical perspective. J. Appl. Physiol. 101, 628-634 (2006).
    • (2006) J. Appl. Physiol. , vol.101 , pp. 628-634
    • Widdicombe, J.1
  • 38
    • 4344601793 scopus 로고    scopus 로고
    • Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice
    • Vanoirbeek, J.A. et al. Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. Toxicol. Sci. 80, 310-321 (2004).
    • (2004) Toxicol. Sci. , vol.80 , pp. 310-321
    • Vanoirbeek, J.A.1
  • 39
    • 42449091544 scopus 로고    scopus 로고
    • The menthol smoker: Tobacco industry research on consumer sensory perception of menthol cigarettes and its role in smoking behavior
    • Kreslake, J.M., Wayne, G.F. & Connolly, G.N. The menthol smoker: tobacco industry research on consumer sensory perception of menthol cigarettes and its role in smoking behavior. Nicotine Tob. Res. 10, 705-715 (2008).
    • (2008) Nicotine Tob. Res. , vol.10 , pp. 705-715
    • Kreslake, J.M.1    Wayne, G.F.2    Connolly, G.N.3
  • 40
    • 0034992898 scopus 로고    scopus 로고
    • Oral irritant properties of menthol: Sensitizing and desensitizing effects of repeated application and cross-desensitization to nicotine
    • Dessirier, J.M., O'Mahony, M. & Carstens, E. Oral irritant properties of menthol: sensitizing and desensitizing effects of repeated application and cross-desensitization to nicotine. Physiol. Behav. 73, 25-36 (2001).
    • (2001) Physiol. Behav. , vol.73 , pp. 25-36
    • Dessirier, J.M.1    O'Mahony, M.2    Carstens, E.3
  • 41
    • 33846911018 scopus 로고    scopus 로고
    • Neurons in superfcial trigeminal subnucleus caudalis responsive to oral cooling, menthol and other irritant stimuli
    • Zanotto, K.L., Merrill, A.W., Carstens, M.I. & Carstens, E. Neurons in superfcial trigeminal subnucleus caudalis responsive to oral cooling, menthol and other irritant stimuli. J. Neurophysiol. 97, 966-978 (2007).
    • (2007) J. Neurophysiol. , vol.97 , pp. 966-978
    • Zanotto, K.L.1    Merrill, A.W.2    Carstens, M.I.3    Carstens, E.4
  • 42
    • 2642568616 scopus 로고    scopus 로고
    • 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3
    • Chung, M.K., Lee, H., Mizuno, A., Suzuki, M. & Caterina, M.J. 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J. Neurosci. 24, 5177-5182 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 5177-5182
    • Chung, M.K.1    Lee, H.2    Mizuno, A.3    Suzuki, M.4    Caterina, M.J.5
  • 43
    • 1642361748 scopus 로고    scopus 로고
    • Measuring tobacco smoke exposure: Quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods
    • Dhar, P. Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J. Pharm. Biomed. Anal. 35, 155-168 (2004).
    • (2004) J. Pharm. Biomed. Anal. , vol.35 , pp. 155-168
    • Dhar, P.1
  • 44
    • 37149011085 scopus 로고    scopus 로고
    • Time course of self-desensitization of oral irritation by nicotine and capsaicin
    • Carstens, E., Albin, K.C., Simons, C.T. & Carstens, M.I. Time course of self-desensitization of oral irritation by nicotine and capsaicin. Chem. Senses 32, 811-816 (2007).
    • (2007) Chem. Senses , vol.32 , pp. 811-816
    • Carstens, E.1    Albin, K.C.2    Simons, C.T.3    Carstens, M.I.4
  • 45
    • 0032721860 scopus 로고    scopus 로고
    • Mechanisms of nose-lung interaction
    • Togias, A. Mechanisms of nose-lung interaction. Allergy 54 Suppl 57: 94-105 (1999).
    • (1999) Allergy 54 Suppl , vol.57 , pp. 94-105
    • Togias, A.1
  • 46
    • 34247487011 scopus 로고    scopus 로고
    • TRPM8 is required for cold sensation in mice
    • Dhaka, A. et al. TRPM8 is required for cold sensation in mice. Neuron 54, 371-378 (2007).
    • (2007) Neuron , vol.54 , pp. 371-378
    • Dhaka, A.1
  • 47
    • 0343262657 scopus 로고    scopus 로고
    • Myrosinase: Gene family evolution and herbivore defense in Brassicaceae
    • Rask, L. et al. Myrosinase: gene family evolution and herbivore defense in Brassicaceae. Plant Mol. Biol. 42, 93-113 (2000).
    • (2000) Plant Mol. Biol. , vol.42 , pp. 93-113
    • Rask, L.1
  • 48
    • 0001143430 scopus 로고
    • Alkaloidal responses to damage in Nicotiana native to North America
    • Baldwin, I. & Ohnmeiss, T. Alkaloidal responses to damage in Nicotiana native to North America. J. Chem. Ecol. 19, 1143-1153 (1993).
    • (1993) J. Chem. Ecol. , vol.19 , pp. 1143-1153
    • Baldwin, I.1    Ohnmeiss, T.2
  • 50
    • 0036087495 scopus 로고    scopus 로고
    • Distribution of intranasal instillations in mice: Effects of volume, time, body position and anesthesia
    • Southam, D.S., Dolovich, M., O'Byrne, P.M. & Inman, M.D. Distribution of intranasal instillations in mice: effects of volume, time, body position and anesthesia. Am. J. Physiol. Lung Cell. Mol. Physiol. 282, L833-L839 (2002)
    • (2002) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.282
    • Southam, D.S.1    Dolovich, M.2    O'Byrne, P.M.3    Inman, M.D.4


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