Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases

Biochemical Pharmacology

Volumn 84, Issue 5, 2012, Pages 581-590

  Lee, I Ta ^a   Yang, Chuen Mao ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Antioxidants; Inflammation; NADPH oxidase; Reactive oxygen species; Respiratory inflammatory diseases; Signaling pathways

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ASCORBIC ACID; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; EPIDERMAL GROWTH FACTOR; ERDOSTEINE; GELATINASE B; GLUTAREDOXIN; HYPOXIA INDUCIBLE FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; NORPHENAZONE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RESVERATROL; SUPEROXIDE DISMUTASE; THIOREDOXIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN RECEPTOR; XANTHINE OXIDASE;

ACUTE LUNG INJURY; ALZHEIMER DISEASE; ANTIGEN PRESENTING CELL; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYSTIC FIBROSIS; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FIBROSING ALVEOLITIS; GENE EXPRESSION; HISTONE MODIFICATION; HUMAN; LUNG CANCER; LUNG DISEASE; LUNG FIBROSIS; LUNG INJURY; MACROPHAGE; MITOCHONDRIAL ENERGY TRANSFER; MULTIPLE SCLEROSIS; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN TARGETING; RESPIRATORY DISTRESS; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; REVIEW; SIGNAL TRANSDUCTION;

EID: 84864403641     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.05.005     Document Type: Review

References (75)

1. I. Rahman, and W. MacNee Oxidative stress and regulation of glutathione in lung inflammation Eur Respir J 16 2000 534 554
2. W. Droge Free radicals in the physiological control of cell function Physiol Rev 82 2002 47 95
3. S.S. Barbieri, E. Zacchi, P. Amadio, S. Gianellini, L. Mussoni, and B.B. Weksler Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction Cardiovasc Res 90 2011 475 483
4. I.T. Lee, S.F. Luo, C.W. Lee, S.W. Wang, C.C. Lin, and C.C. Chang Overexpression of HO-1 protects against TNF-α-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress Am J Pathol 175 2009 519 532
5. 2 by TNF-α mediated through Nox2, MAPKs, NF-(B, and p300 in human tracheal smooth muscle cells J Cell Physiol 226 2011 2103 2114
6. C.P. Lin, P.H. Huang, H.S. Tsai, T.C. Wu, H.B. Leu, and P.L. Liu Monascus purpureus-fermented rice inhibits tumor necrosis factor-α-induced upregulation of matrix metalloproteinase 2 and 9 in human aortic smooth muscle cells J Pharm Pharmacol 63 2011 1587 1594
7. 2+/CaM kinase II are necessary for VCAM-1 induction in IL-1β-treated human tracheal smooth muscle cells Toxicol Appl Pharmacol 237 2009 8 21
8. H.S. Park, S.R. Kim, and Y.C. Lee Impact of oxidative stress on lung diseases Respirology 14 2009 27 38
9. I. Rahman, and I.M. Adcock Oxidative stress and redox regulation of lung inflammation in COPD Eur Respir J 28 2006 219 242
10. I. Rahman, S.K. Biswas, and A. Kode Oxidant and antioxidant balance in the airways and airway diseases Eur J Pharmacol 533 2006 222 239
11. K. Bedard, and K.H. Krause The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology Physiol Rev 87 2007 245 313
12. S. Pendyala, and V. Natarajan Redox regulation of Nox proteins Respir Physiol Neurobiol 174 2010 265 271
13. I. Rahman, and W. MacNee Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches Free Radic Biol Med 28 2000 1405 1420
14. I. Rahman, B. Mulier, P.S. Gilmour, T. Watchorn, K. Donaldson, and P.K. Jeffery Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-κB Biochem Pharmacol 62 2001 787 794
15. S. Dikalov Cross talk between mitochondria and NADPH oxidases Free Radic Biol Med 51 2011 1289 1301
16. S. Phalitakul, M. Okada, Y. Hara, and H. Yamawaki Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells Pharmacol Res 64 2011 493 500
17. M.X. Shao, and J.A. Nadel Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-α-converting enzyme J Immunol 175 2005 4009 4016
18. A. Ptasznik, E.R. Prossnitz, D. Yoshikawa, A. Smrcka, A.E. Traynor-Kaplan, and G.M. Bokoch A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophils J Biol Chem 271 1996 25204 25207
19. 2 preconditioning modulates phase II enzymes through p38 MAPK and PI3K/Akt activation Am J Physiol Heart Circ Physiol 300 2011 H2196 H2205
20. J. Pan, Q. Chang, X. Wang, Y. Son, Z. Zhang, and G. Chen Reactive oxygen species-activated Akt/ASK1/p38 signaling pathway in nickel compound-induced apoptosis in BEAS 2B cells Chem Res Toxicol 23 2010 568 577
21. G. Neufeld, T. Cohen, S. Gengrinovitch, and Z. Poltorak Vascular endothelial growth factor (VEGF) and its receptors FASEB J 13 1999 9 22
22. H. Lei, and A. Kazlauskas Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells J Biol Chem 284 2009 6329 6336
23. K.C. Chen, Y. Zhou, K. Xing, K. Krysan, and M.F. Lou Platelet derived growth factor (PDGF)-induced reactive oxygen species in the lens epithelial cells: the redox signaling Exp Eye Res 78 2004 1057 1067
24. 2/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: role of TLR4-dependent NADPH oxidase activation Free Radic Biol Med 48 2010 240 254
25. C.M. Yang, C.C. Lin, I.T. Lee, Y.H. Lin, C.M. Yang, and W.J. Chen Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes J Neuroinflammation 9 2012 12
26. Y.C. Lee, K.S. Lee, S.J. Park, H.S. Park, J.S. Lim, and K.H. Park Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid FASEB J 18 2004 1917 1919
27. M. Mata, E. Morcillo, C. Gimeno, and J. Cortijo N-acetyl-l-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory mediators in alveolar type II epithelial cells infected with influenza virus A and B and with respiratory syncytial virus (RSV) Biochem Pharmacol 82 2011 548 555
28. J.H. Oh, E.J. Park, J.W. Park, J. Lee, S.H. Lee, and T.K. Kwon A novel cyclin-dependent kinase inhibitor down-regulates tumor necrosis factor-α (TNF-α)-induced expression of cell adhesion molecules by inhibition of NF-κB activation in human pulmonary epithelial cells Int Immunopharmacol 10 2010 572 579
29. Y. Jing, L.Z. Liu, Y. Jiang, Y. Zhu, N.L. Guo, and J. Barnett Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells Toxicol Sci 125 2012 10 19
30. K.S. Lee, S.R. Kim, H.S. Park, S.J. Park, K.H. Min, and K.Y. Lee A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-κB and hypoxia-inducible factor-1α Exp Mol Med 39 2007 756 768
31. K.S. Lee, S.R. Kim, S.J. Park, H.S. Park, K.H. Min, and M.H. Lee Hydrogen peroxide induces vascular permeability via regulation of vascular endothelial growth factor Am J Respir Cell Mol Biol 35 2006 190 197
32. R. Datta, D.E. Hallahan, S.M. Kharbanda, E. Rubin, M.L. Sherman, and E. Huberman Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation Biochemistry 31 1992 8300 8306
33. S.Y. Kim, K.A. Moon, H.Y. Jo, S. Jeong, S.H. Seon, and E. Jung Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation Immunol Cell Biol 2011
34. I. Rahman Oxidative stress, transcription factors and chromatin remodelling in lung inflammation Biochem Pharmacol 64 2002 935 942
35. 10- induced transcription of interleukin-8 Am J Physiol Lung Cell Mol Physiol 281 2001 L598 L606
36. R.P. Bowler Oxidative stress in the pathogenesis of asthma Curr Allergy Asthma Rep 4 2004 116 122
37. I. Rahman, and W. MacNee Role of oxidants/antioxidants in smoking-induced lung diseases Free Radic Biol Med 21 1996 669 681
38. 1-antitrypsin deficiency Proc Am Thorac Soc 7 2010 381 386
39. 2α, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro Am J Respir Crit Care Med 153 1996 590 596
40. B. Zhang, Z.Y. Liu, Y.Y. Li, Y. Luo, M.L. Liu, and H.Y. Dong Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice Eur J Pharm Sci 44 2011 573 579
41. X. Qiu, H. Li, H. Tang, Y. Jin, W. Li, and X. YuSun PingFeng Sun Hydrogen inhalation ameliorates lipopolysaccharide-induced acute lung injury in mice Int Immunopharmacol 11 2011 2130 2137
42. W.J. Zhang, H. Wei, Y.T. Tien, and B. Frei Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues Free Radic Biol Med 50 2011 1517 1525
43. Y.A. Suh, R.S. Arnold, B. Lassegue, J. Shi, X. Xu, and D. Sorescu Cell transformation by the superoxide-generating oxidase Mox1 Nature 401 1999 79 82
44. R.S. Arnold, J. Shi, E. Murad, A.M. Whalen, C.Q. Sun, and R. Polavarapu Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1 Proc Natl Acad Sci U S A 98 2001 5550 5555
45. S. Luxen, S.A. Belinsky, and U.G. Knaus Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer Cancer Res 68 2008 1037 1045
46. G. Caramori, I.M. Adcock, P. Casolari, K. Ito, E. Jazrawi, and L. Tsaprouni Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer Thorax 66 2011 521 527
47. A.M. Cantin, S.L. North, G.A. Fells, R.C. Hubbard, and R.G. Crystal Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis J Clin Invest 79 1987 1665 1673
48. M. Waghray, Z. Cui, J.C. Horowitz, I.M. Subramanian, F.J. Martinez, and G.B. Toews Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts FASEB J 19 2005 854 856
49. Y. Cui, J. Robertson, S. Maharaj, L. Waldhauser, J. Niu, and J. Wang Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis Int J Biochem Cell Biol 43 2011 1122 1133
50. S. Carnesecchi, C. Deffert, Y. Donati, O. Basset, B. Hinz, and O. Preynat-Seauve A key role for NOX4 in epithelial cell death during development of lung fibrosis Antioxid Redox Signal 15 2011 607 619
51. N. Sriram, S. Kalayarasan, and G. Sudhandiran Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling Pulm Pharmacol Ther 22 2009 221 236
52. M.F. Allam, and R.A. Lucane Selenium supplementation for asthma CDS Rev 2004 CD003538
53. B. Ekstrand-Hammarstrom, C. Osterlund, B. Lilliehook, and A. Bucht Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-κB and inflammatory responses in lung epithelial cells Clin Exp Immunol 147 2007 359 369
54. N. Morita, K. Shimoda, M.G. Traber, M. Westphal, P. Enkhbaatar, and K. Murakami Vitamin E attenuates acute lung injury in sheep with burn and smoke inhalation injury Redox Rep 11 2006 61 70
55. M. Tanaka Pharmacological and clinical profile of the free radical scavenger edaravone as a neuroprotective agent Nippon Yakurigaku Zasshi 119 2002 301 308
56. Q. Zhi, H. Sun, X. Qian, and L. Yang Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat Int Immunopharmacol 11 2011 96 102
57. S. Tajima, M. Bando, Y. Ishii, T. Hosono, H. Yamasawa, and S. Ohno Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice Eur Respir J 32 2008 1337 1343
58. M.M. Bridgeman, M. Marsden, W. MacNee, D.C. Flenley, and A.P. Ryle Cysteine and glutathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine Thorax 46 1991 39 42
59. M. Linden, E. Wieslander, A. Eklund, K. Larsson, and R. Brattsand Effects of oral N-acetylcysteine on cell content and macrophage function in bronchoalveolar lavage from healthy smokers Eur Respir J 1 1988 645 650
60. R. Jankowska, E. Passowicz-Muszynska, W. Medrala, T. Banas, and A. Marcinkowska The influence of n-acetylcysteine on chemiluminescence of granulocytes in peripheral blood of patients with chronic bronchitis Pneumonol Alergol Pol 61 1993 586 591
61. J. Amer, D. Atlas, and E. Fibach N-Acetylcysteine amide (AD4) attenuates oxidative stress in β-thalassemia blood cells Biochim Biophys Acta 1780 2008 249 255
62. T. Nordman, L. Xia, L. Björkhem-Bergman, A. Damdimopoulos, I. Nalvarte, and E.S. Arnér Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase Biofactors 18 2003 45 50
63. J. Xu, T. Li, H. Wu, and T. Xu Role of thioredoxin in lung disease Pulm Pharmacol Ther 2012
64. M. Torii, L. Wang, N. Ma, K. Saito, T. Hori, and M. Sato-Ueshima Thioredoxin suppresses airway inflammation independently of systemic Th1/Th2 immune modulation Eur J Immunol 40 2010 787 796
65. N. Kobayashi, Y. Yamada, W. Ito, S. Ueki, H. Kayaba, and H. Nakamura Thioredoxin reduces C-C chemokine-induced chemotaxis of human eosinophils Allergy 64 2009 1130 1135
66. Y. Chen, L. Chang, W. Li, Z. Rong, W. Liu, and R. Shan Thioredoxin protects fetal type II epithelial cells from hyperoxia-induced injury Pediatr Pulmonol 45 2010 1192 1200
67. I. Rahman Antioxidant therapeutic advances in COPD Ther Adv Respir Dis 2 2008 351 374
68. S.Y. Lee, H.J. Lee, M.A. Sikder, H.D. Shin, J.H. Kim, and G.T. Chang Resveratrol inhibits mucin gene expression, production and secretion from airway epithelial cells Phytother Res 2011
69. R. Lopez-Sepulveda, M. Gomez-Guzman, M.J. Zarzuelo, M. Romero, M. Sanchez, and A.M. Quintela Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase Clin Sci (Lond) 120 2011 321 333
70. M. Moretti Pharmacology and clinical efficacy of erdosteine in chronic obstructive pulmonary disease Expert Rev Respir Med 1 2007 307 316
71. R.W. Dal Negro Erdosteine: antitussive and anti-inflammatory effects Lung 186 suppl. 1 2008 S70 S73
72. R.W. Dal Negro, M. Visconti, S. Tognella, and C. Micheletto Erdosteine affects eicosanoid production in COPD Int J Clin Pharmacol Ther 49 2011 41 45
73. L. Marabini, R. Calo, and P.C. Braga Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells Arzneimittelforschung 61 2011 700 706
74. M.D. Shelton, and J.J. Mieyal Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases Mol Cells 25 2008 332 346
75. I. Kuipers, A.S. Guala, S.W. Aesif, G. Konings, F.G. Bouwman, and E.C. Mariman Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death Am J Respir Cell Mol Biol 45 2011 931 937