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Volumn 54, Issue , 2017, Pages 1-15

Metabolism and chromatin dynamics in health and disease

Author keywords

Chromatin; Diabetes; Epigenetics; Glucose; Histones; Metabolism

Indexed keywords

7 (3,5 DIMETHYL 4 ISOXAZOLYL) 1,3 DIHYDRO 8 METHOXY 1 [1 (2 PYRIDINYL)ETHYL] 2H IMIDAZO[4,5 C]QUINOLIN 2 ONE; GIVINOSTAT; HISTONE DEACETYLASE INHIBITOR; HISTONE LYSINE METHYLTRANSFERASE INHIBITOR; SET7; TRICHOSTATIN A; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT; GLUCOSE;

EID: 85008675434     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2016.09.004     Document Type: Review
Times cited : (11)

References (222)
  • 1
    • 79959209876 scopus 로고    scopus 로고
    • Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism
    • Advani, A., Huang, Q., Thai, K., Advani, S.L., White, K.E., Kelly, D.J., et al. Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. Am. J. Pathol 178:5 (2011), 2205–2214.
    • (2011) Am. J. Pathol , vol.178 , Issue.5 , pp. 2205-2214
    • Advani, A.1    Huang, Q.2    Thai, K.3    Advani, S.L.4    White, K.E.5    Kelly, D.J.6
  • 2
    • 84953209314 scopus 로고    scopus 로고
    • Deposition of 5-Methylcytosine on enhancer RNAs enables the coactivator function of PGC-1alpha
    • Aguilo, F., Li, S., Balasubramaniyan, N., Sancho, A., Benko, S., Zhang, F., et al. Deposition of 5-Methylcytosine on enhancer RNAs enables the coactivator function of PGC-1alpha. Cell Rep 14:3 (2016), 479–492.
    • (2016) Cell Rep , vol.14 , Issue.3 , pp. 479-492
    • Aguilo, F.1    Li, S.2    Balasubramaniyan, N.3    Sancho, A.4    Benko, S.5    Zhang, F.6
  • 3
    • 84924365865 scopus 로고    scopus 로고
    • First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes
    • e0119333
    • Anderson, D., Cordell, H.J., Fakiola, M., Francis, R.W., Syn, G., Scaman, E.S.H., et al. First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. PLoS ONE, 10(3), 2015 e0119333.
    • (2015) PLoS ONE , vol.10 , Issue.3
    • Anderson, D.1    Cordell, H.J.2    Fakiola, M.3    Francis, R.W.4    Syn, G.5    Scaman, E.S.H.6
  • 4
    • 84864010293 scopus 로고    scopus 로고
    • Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation
    • Anderson, O.S., Sant, K.E., Dolinoy, D.C., Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation. J. Nutr. Biochem 23:8 (2012), 853–859.
    • (2012) J. Nutr. Biochem , vol.23 , Issue.8 , pp. 853-859
    • Anderson, O.S.1    Sant, K.E.2    Dolinoy, D.C.3
  • 5
    • 0041530268 scopus 로고    scopus 로고
    • Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors
    • Antos, C.L., McKinsey, T.A., Dreitz, M., Hollingsworth, L.M., Zhang, C.-L., Schreiber, K., et al. Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors. J. Biol. Chem 278:31 (2003), 28930–28937.
    • (2003) J. Biol. Chem , vol.278 , Issue.31 , pp. 28930-28937
    • Antos, C.L.1    McKinsey, T.A.2    Dreitz, M.3    Hollingsworth, L.M.4    Zhang, C.-L.5    Schreiber, K.6
  • 6
    • 34548418914 scopus 로고    scopus 로고
    • A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis
    • Babu, D.A., Deering, T.G., Mirmira, R.G., A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. Mol. Genet. Metab 92 (2007), 43–55.
    • (2007) Mol. Genet. Metab , vol.92 , pp. 43-55
    • Babu, D.A.1    Deering, T.G.2    Mirmira, R.G.3
  • 7
    • 84923080018 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerases as modulators of mitochondrial activity
    • Bai, P., Nagy, L., Fodor, T., Liaudet, L., Pacher, P., Poly(ADP-ribose) polymerases as modulators of mitochondrial activity. Trends Endocrinol. Metab 26:2 (2015), 75–83.
    • (2015) Trends Endocrinol. Metab , vol.26 , Issue.2 , pp. 75-83
    • Bai, P.1    Nagy, L.2    Fodor, T.3    Liaudet, L.4    Pacher, P.5
  • 8
    • 69149087790 scopus 로고    scopus 로고
    • Non-CpG methylation of the PGC-1α promoter through DNMT3B controls mitochondrial density
    • Barrès, R., Osler, M.E., Yan, J., Rune, A., Fritz, T., Caidahl, K., et al. Non-CpG methylation of the PGC-1α promoter through DNMT3B controls mitochondrial density. Cell Metab 10:3 (2009), 189–198.
    • (2009) Cell Metab , vol.10 , Issue.3 , pp. 189-198
    • Barrès, R.1    Osler, M.E.2    Yan, J.3    Rune, A.4    Fritz, T.5    Caidahl, K.6
  • 9
    • 84858055958 scopus 로고    scopus 로고
    • Acute exercise remodels promoter methylation in human skeletal muscle
    • Barrès, R., Yan, J., Egan, B., Treebak, J.T., Rasmussen, M., Fritz, T., et al. Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metab 15:3 (2012), 405–411.
    • (2012) Cell Metab , vol.15 , Issue.3 , pp. 405-411
    • Barrès, R.1    Yan, J.2    Egan, B.3    Treebak, J.T.4    Rasmussen, M.5    Fritz, T.6
  • 10
    • 84885125282 scopus 로고    scopus 로고
    • 17-β Oestradiol prevents cardiovascular dysfunction in post-menopausal metabolic syndrome by affecting SIRT1/AMPK/H3 acetylation
    • Bendale, D.S., Karpe, P.A., Chhabra, R., Shete, S.P., Shah, H., Tikoo, K., 17-β Oestradiol prevents cardiovascular dysfunction in post-menopausal metabolic syndrome by affecting SIRT1/AMPK/H3 acetylation. Br. J. Pharmacol 170:4 (2013), 779–795.
    • (2013) Br. J. Pharmacol , vol.170 , Issue.4 , pp. 779-795
    • Bendale, D.S.1    Karpe, P.A.2    Chhabra, R.3    Shete, S.P.4    Shah, H.5    Tikoo, K.6
  • 11
    • 19944430797 scopus 로고    scopus 로고
    • Genomic maps and comparative analysis of histone modifications in human and mouse
    • Bernstein, B.E., Kamal, M., Lindblad-Toh, K., Bekiranov, S., Bailey, D.K., Huebert, D.J., et al. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell 120:2 (2005), 169–181.
    • (2005) Cell , vol.120 , Issue.2 , pp. 169-181
    • Bernstein, B.E.1    Kamal, M.2    Lindblad-Toh, K.3    Bekiranov, S.4    Bailey, D.K.5    Huebert, D.J.6
  • 14
    • 84928254126 scopus 로고    scopus 로고
    • A little sugar goes a long way: the cell biology of O-GlcNAc
    • Bond, M.R., Hanover, J.A., A little sugar goes a long way: the cell biology of O-GlcNAc. J. Cell Biol 208:7 (2015), 869–880.
    • (2015) J. Cell Biol , vol.208 , Issue.7 , pp. 869-880
    • Bond, M.R.1    Hanover, J.A.2
  • 15
    • 65549170303 scopus 로고    scopus 로고
    • Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
    • Brasacchio, D., Okabe, J., Tikellis, C., Balcerczyk, A., George, P., Baker, E.K., et al. Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes 58 (2009), 1229–1236.
    • (2009) Diabetes , vol.58 , pp. 1229-1236
    • Brasacchio, D.1    Okabe, J.2    Tikellis, C.3    Balcerczyk, A.4    George, P.5    Baker, E.K.6
  • 17
    • 77954523386 scopus 로고    scopus 로고
    • Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner
    • Brøns, C., Jacobsen, S., Nilsson, E., Rönn, T., Jensen, C.B., Storgaard, H., et al. Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner. J. Clin. Endocrinol. Metab 95:6 (2010), 3048–3056.
    • (2010) J. Clin. Endocrinol. Metab , vol.95 , Issue.6 , pp. 3048-3056
    • Brøns, C.1    Jacobsen, S.2    Nilsson, E.3    Rönn, T.4    Jensen, C.B.5    Storgaard, H.6
  • 19
    • 77956294919 scopus 로고    scopus 로고
    • Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation
    • Bungard, D., Fuerth, B.J., Zeng, P.Y., Faubert, B., Maas, N.L., Viollet, B., et al. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science 329:5996 (2010), 1201–1205.
    • (2010) Science , vol.329 , Issue.5996 , pp. 1201-1205
    • Bungard, D.1    Fuerth, B.J.2    Zeng, P.Y.3    Faubert, B.4    Maas, N.L.5    Viollet, B.6
  • 20
    • 84942817340 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients
    • Buraczynska, M., Dragan, M., Buraczynska, K., Orlowska-Kowalik, G., Ksiazek, A., Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients. J. Diabetes Complications 29:6 (2015), 829–833.
    • (2015) J. Diabetes Complications , vol.29 , Issue.6 , pp. 829-833
    • Buraczynska, M.1    Dragan, M.2    Buraczynska, K.3    Orlowska-Kowalik, G.4    Ksiazek, A.5
  • 21
    • 33644873810 scopus 로고    scopus 로고
    • Hexosamines, insulin resistance, and the complications of diabetes: current status
    • Buse, M.G., Hexosamines, insulin resistance, and the complications of diabetes: current status. Am. J. Physiol. Endocrinol. Metab 290:1 (2006), E1–E8.
    • (2006) Am. J. Physiol. Endocrinol. Metab , vol.290 , Issue.1 , pp. E1-E8
    • Buse, M.G.1
  • 22
    • 79955960768 scopus 로고    scopus 로고
    • Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes
    • Cai, L., Sutter, B.M., Li, B., Tu, B.P., Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. Mol. Cell 42:4 (2011), 426–437.
    • (2011) Mol. Cell , vol.42 , Issue.4 , pp. 426-437
    • Cai, L.1    Sutter, B.M.2    Li, B.3    Tu, B.P.4
  • 23
    • 67349276169 scopus 로고    scopus 로고
    • AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
    • Canto, C., Gerhart-Hines, Z., Feige, J.N., Lagouge, M., Noriega, L., Milne, J.C., et al. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458:7241 (2009), 1056–1060.
    • (2009) Nature , vol.458 , Issue.7241 , pp. 1056-1060
    • Canto, C.1    Gerhart-Hines, Z.2    Feige, J.N.3    Lagouge, M.4    Noriega, L.5    Milne, J.C.6
  • 24
    • 53749094476 scopus 로고    scopus 로고
    • UKPDS and the legacy effect
    • Chalmers, J., Cooper, M.E., UKPDS and the legacy effect. N. Engl. J. Med 359:15 (2008), 1618–1620.
    • (2008) N. Engl. J. Med , vol.359 , Issue.15 , pp. 1618-1620
    • Chalmers, J.1    Cooper, M.E.2
  • 25
    • 77449151150 scopus 로고    scopus 로고
    • Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid–induced ER stress–mediated β-cell death
    • Chen, J., Fontes, G., Saxena, G., Poitout, V., Shalev, A., Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid–induced ER stress–mediated β-cell death. Diabetes 59:2 (2010), 440–447.
    • (2010) Diabetes , vol.59 , Issue.2 , pp. 440-447
    • Chen, J.1    Fontes, G.2    Saxena, G.3    Poitout, V.4    Shalev, A.5
  • 26
    • 84900522497 scopus 로고    scopus 로고
    • ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db mice
    • Chen, J., Guo, Y., Zeng, W., Huang, L., Pang, Q., Nie, L., et al. ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db mice. Am. J. Physiol. Renal Physiol 306:8 (2014), F916–F925.
    • (2014) Am. J. Physiol. Renal Physiol , vol.306 , Issue.8 , pp. F916-F925
    • Chen, J.1    Guo, Y.2    Zeng, W.3    Huang, L.4    Pang, Q.5    Nie, L.6
  • 27
    • 84969776770 scopus 로고    scopus 로고
    • Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort
    • Chen, Z., Miao, F., Paterson, A.D., Lachin, J.M., Zhang, L., Schones, D.E., et al. Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort. Proc. Natl. Acad. Sci. U.S.A. 113:21 (2016), E3002–E3011.
    • (2016) Proc. Natl. Acad. Sci. U.S.A. , vol.113 , Issue.21 , pp. E3002-E3011
    • Chen, Z.1    Miao, F.2    Paterson, A.D.3    Lachin, J.M.4    Zhang, L.5    Schones, D.E.6
  • 28
    • 84867169367 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner
    • Choi, D., Oh, K.-J., Han, H.-S., Yoon, Y.-S., Jung, C.-Y., Kim, S.-T., et al. Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner. Hepatology 56:4 (2012), 1546–1556.
    • (2012) Hepatology , vol.56 , Issue.4 , pp. 1546-1556
    • Choi, D.1    Oh, K.-J.2    Han, H.-S.3    Yoon, Y.-S.4    Jung, C.-Y.5    Kim, S.-T.6
  • 29
    • 84862726998 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis
    • Chou, D.H., Holson, E.B., Wagner, F.F., Tang, A.J., Maglathlin, R.L., Lewis, T.A., et al. Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis. Chem. Biol 19:6 (2012), 669–673.
    • (2012) Chem. Biol , vol.19 , Issue.6 , pp. 669-673
    • Chou, D.H.1    Holson, E.B.2    Wagner, F.F.3    Tang, A.J.4    Maglathlin, R.L.5    Lewis, T.A.6
  • 30
    • 84892938274 scopus 로고    scopus 로고
    • Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
    • Christensen, D.P., Gysemans, C., Lundh, M., Dahllöf, M.S., Noesgaard, D., Schmidt, S.F., et al. Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection. Proc. Natl. Acad. Sci. U.S.A. 111:3 (2014), 1055–1059.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , Issue.3 , pp. 1055-1059
    • Christensen, D.P.1    Gysemans, C.2    Lundh, M.3    Dahllöf, M.S.4    Noesgaard, D.5    Schmidt, S.F.6
  • 32
    • 84949324174 scopus 로고    scopus 로고
    • Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle
    • Ciccarelli, M., Vastolo, V., Albano, L., Lecce, M., Cabaro, S., Liotti, A., et al. Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle. Diabetologia 59:1 (2016), 176–186.
    • (2016) Diabetologia , vol.59 , Issue.1 , pp. 176-186
    • Ciccarelli, M.1    Vastolo, V.2    Albano, L.3    Lecce, M.4    Cabaro, S.5    Liotti, A.6
  • 33
    • 84955611443 scopus 로고    scopus 로고
    • Trim28 haploinsufficiency triggers bi-stable epigenetic obesity
    • Dalgaard, K., Landgraf, K., Heyne, S., Lempradl, A., Longinotto, J., Gossens, K., et al. Trim28 haploinsufficiency triggers bi-stable epigenetic obesity. Cell 164:3 (2016), 353–364.
    • (2016) Cell , vol.164 , Issue.3 , pp. 353-364
    • Dalgaard, K.1    Landgraf, K.2    Heyne, S.3    Lempradl, A.4    Longinotto, J.5    Gossens, K.6
  • 34
    • 85002669967 scopus 로고    scopus 로고
    • Association of DNA methylation at CPT1A locus with metabolic syndrome in the genetics of lipid lowering drugs and diet network (GOLDN) study
    • e0145789
    • Das, M., Sha, J., Hidalgo, B., Aslibekyan, S., Do, A.N., Zhi, D., et al. Association of DNA methylation at CPT1A locus with metabolic syndrome in the genetics of lipid lowering drugs and diet network (GOLDN) study. PLoS ONE, 11(1), 2016 e0145789.
    • (2016) PLoS ONE , vol.11 , Issue.1
    • Das, M.1    Sha, J.2    Hidalgo, B.3    Aslibekyan, S.4    Do, A.N.5    Zhi, D.6
  • 35
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • DCCT, The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med 329:14 (1993), 977–986.
    • (1993) N. Engl. J. Med , vol.329 , Issue.14 , pp. 977-986
    • DCCT1
  • 36
    • 0034628425 scopus 로고    scopus 로고
    • Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy
    • DCCT/EDIC, Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N. Engl. J. Med 342:6 (2000), 381–389.
    • (2000) N. Engl. J. Med , vol.342 , Issue.6 , pp. 381-389
    • DCCT/EDIC1
  • 37
    • 0142087597 scopus 로고    scopus 로고
    • Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study
    • DCCT/EDIC, Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA 290:16 (2003), 2159–2167.
    • (2003) JAMA , vol.290 , Issue.16 , pp. 2159-2167
    • DCCT/EDIC1
  • 39
    • 63249112026 scopus 로고    scopus 로고
    • Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes
    • Deering, T.G., Ogihara, T., Trace, A.P., Maier, B., Mirmira, R.G., Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes 58:1 (2009), 185–193.
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 185-193
    • Deering, T.G.1    Ogihara, T.2    Trace, A.P.3    Maier, B.4    Mirmira, R.G.5
  • 40
    • 84936797255 scopus 로고    scopus 로고
    • DNA methylation directs functional maturation of pancreatic β cells
    • Dhawan, S., Tschen, S.-I., Zeng, C., Guo, T., Hebrok, M., Matveyenko, A., et al. DNA methylation directs functional maturation of pancreatic β cells. J. Clin. Invest 125:7 (2015), 2851–2860.
    • (2015) J. Clin. Invest , vol.125 , Issue.7 , pp. 2851-2860
    • Dhawan, S.1    Tschen, S.-I.2    Zeng, C.3    Guo, T.4    Hebrok, M.5    Matveyenko, A.6
  • 41
    • 70350313230 scopus 로고    scopus 로고
    • Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice
    • Dunn, G.A., Bale, T.L., Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology 150:11 (2009), 4999–5009.
    • (2009) Endocrinology , vol.150 , Issue.11 , pp. 4999-5009
    • Dunn, G.A.1    Bale, T.L.2
  • 42
    • 84957028316 scopus 로고    scopus 로고
    • O-linked beta-N-acetylglucosamine (O-GlcNAc) acts as a glucose sensor to epigenetically regulate the insulin gene in pancreatic beta cells
    • Durning, S.P., Flanagan-Steet, H., Prasad, N., Wells, L., O-linked beta-N-acetylglucosamine (O-GlcNAc) acts as a glucose sensor to epigenetically regulate the insulin gene in pancreatic beta cells. J. Biol. Chem 291:5 (2016), 2107–2118.
    • (2016) J. Biol. Chem , vol.291 , Issue.5 , pp. 2107-2118
    • Durning, S.P.1    Flanagan-Steet, H.2    Prasad, N.3    Wells, L.4
  • 43
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El-Osta, A., Brasacchio, D., Yao, D., Pocai, A., Jones, P.L., Roeder, R.G., et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J. Exp. Med 205:10 (2008), 2409–2417.
    • (2008) J. Exp. Med , vol.205 , Issue.10 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6
  • 44
    • 84897567792 scopus 로고    scopus 로고
    • Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy
    • Eom, G.H., Nam, Y.S., Oh, J.G., Choe, N., Min, H.K., Yoo, E.K., et al. Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy. Circ. Res 114:7 (2014), 1133–1143.
    • (2014) Circ. Res , vol.114 , Issue.7 , pp. 1133-1143
    • Eom, G.H.1    Nam, Y.S.2    Oh, J.G.3    Choe, N.4    Min, H.K.5    Yoo, E.K.6
  • 45
    • 84876898716 scopus 로고    scopus 로고
    • Quantitative dynamics of the link between cellular metabolism and histone acetylation
    • Evertts, A.G., Zee, B.M., Dimaggio, P.A., Gonzales-Cope, M., Coller, H.A., Garcia, B.A., Quantitative dynamics of the link between cellular metabolism and histone acetylation. J. Biol. Chem 288:17 (2013), 12142–12151.
    • (2013) J. Biol. Chem , vol.288 , Issue.17 , pp. 12142-12151
    • Evertts, A.G.1    Zee, B.M.2    Dimaggio, P.A.3    Gonzales-Cope, M.4    Coller, H.A.5    Garcia, B.A.6
  • 46
    • 58049206267 scopus 로고    scopus 로고
    • The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP
    • Fang, S., Tsang, S., Jones, R., Ponugoti, B., Yoon, H., Wu, S.-Y., et al. The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP. J. Biol. Chem 283:50 (2008), 35086–35095.
    • (2008) J. Biol. Chem , vol.283 , Issue.50 , pp. 35086-35095
    • Fang, S.1    Tsang, S.2    Jones, R.3    Ponugoti, B.4    Yoon, H.5    Wu, S.-Y.6
  • 47
    • 84910137512 scopus 로고    scopus 로고
    • Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis
    • Feil, S., Fehrenbacher, B., Lukowski, R., Essmann, F., Schulze-Osthoff, K., Schaller, M., et al. Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis. Circ. Res 115:7 (2014), 662–667.
    • (2014) Circ. Res , vol.115 , Issue.7 , pp. 662-667
    • Feil, S.1    Fehrenbacher, B.2    Lukowski, R.3    Essmann, F.4    Schulze-Osthoff, K.5    Schaller, M.6
  • 49
    • 84899973908 scopus 로고    scopus 로고
    • Targeting bromodomains: epigenetic readers of lysine acetylation
    • Filippakopoulos, P., Knapp, S., Targeting bromodomains: epigenetic readers of lysine acetylation. Nat. Rev. Drug Discov 13:5 (2014), 337–356.
    • (2014) Nat. Rev. Drug Discov , vol.13 , Issue.5 , pp. 337-356
    • Filippakopoulos, P.1    Knapp, S.2
  • 50
    • 33747081065 scopus 로고    scopus 로고
    • Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer
    • Forsythe, M.E., Love, D.C., Lazarus, B.D., Kim, E.J., Prinz, W.A., Ashwell, G., et al. Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer. Proc. Natl. Acad. Sci. U.S.A. 103:32 (2006), 11952–11957.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , Issue.32 , pp. 11952-11957
    • Forsythe, M.E.1    Love, D.C.2    Lazarus, B.D.3    Kim, E.J.4    Prinz, W.A.5    Ashwell, G.6
  • 51
    • 27744606538 scopus 로고    scopus 로고
    • Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription
    • Francis, J., Chakrabarti, S.K., Garmey, J.C., Mirmira, R.G., Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J. Biol. Chem 280 (2005), 36244–36253.
    • (2005) J. Biol. Chem , vol.280 , pp. 36244-36253
    • Francis, J.1    Chakrabarti, S.K.2    Garmey, J.C.3    Mirmira, R.G.4
  • 52
    • 84923029507 scopus 로고    scopus 로고
    • Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and beta cells
    • Fu, W., Farache, J., Clardy, S.M., Hattori, K., Mander, P., Lee, K., et al. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and beta cells. elife, 3, 2014, e04631.
    • (2014) elife , vol.3 , pp. e04631
    • Fu, W.1    Farache, J.2    Clardy, S.M.3    Hattori, K.4    Mander, P.5    Lee, K.6
  • 53
    • 68249139820 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator activated receptor γ gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes
    • Fujiki, K., Kano, F., Shiota, K., Murata, M., Expression of the peroxisome proliferator activated receptor γ gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. BMC Biol 7:1 (2009), 1–14.
    • (2009) BMC Biol , vol.7 , Issue.1 , pp. 1-14
    • Fujiki, K.1    Kano, F.2    Shiota, K.3    Murata, M.4
  • 54
    • 84885151895 scopus 로고    scopus 로고
    • Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content
    • Fullston, T., Ohlsson Teague, E.M.C., Palmer, N.O., DeBlasio, M.J., Mitchell, M., Corbett, M., et al. Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content. FASEB J. 27:10 (2013), 4226–4243.
    • (2013) FASEB J. , vol.27 , Issue.10 , pp. 4226-4243
    • Fullston, T.1    Ohlsson Teague, E.M.C.2    Palmer, N.O.3    DeBlasio, M.J.4    Mitchell, M.5    Corbett, M.6
  • 55
    • 0037472879 scopus 로고    scopus 로고
    • Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
    • Gæde, P., Vedel, P., Larsen, N., Jensen, G.V.H., Parving, H.-H., Pedersen, O., Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N. Engl. J. Med 348:5 (2003), 383–393.
    • (2003) N. Engl. J. Med , vol.348 , Issue.5 , pp. 383-393
    • Gæde, P.1    Vedel, P.2    Larsen, N.3    Jensen, G.V.H.4    Parving, H.-H.5    Pedersen, O.6
  • 56
    • 84878129322 scopus 로고    scopus 로고
    • Impact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells
    • Gao, C., Chen, G., Liu, L., Li, X., He, J., Jiang, L., et al. Impact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells. J. Diabetes Res, 2013, 2013, 589474.
    • (2013) J. Diabetes Res , vol.2013 , pp. 589474
    • Gao, C.1    Chen, G.2    Liu, L.3    Li, X.4    He, J.5    Jiang, L.6
  • 57
    • 78650909063 scopus 로고    scopus 로고
    • Glucose metabolism induces mono-ubiquitination of histone H2B in mammalian cells
    • Gao, Z., Xu, C.W., Glucose metabolism induces mono-ubiquitination of histone H2B in mammalian cells. Biochem. Biophys. Res. Commun 404:1 (2011), 428–433.
    • (2011) Biochem. Biophys. Res. Commun , vol.404 , Issue.1 , pp. 428-433
    • Gao, Z.1    Xu, C.W.2
  • 58
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco, F., Brownlee, M., Oxidative stress and diabetic complications. Circ. Res 107:9 (2010), 1058–1070.
    • (2010) Circ. Res , vol.107 , Issue.9 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 59
    • 79957815262 scopus 로고    scopus 로고
    • Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor
    • Gilbert, R.E., Huang, Q., Thai, K., Advani, S.L., Lee, K., Yuen, D.A., et al. Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor. Kidney Int 79:12 (2011), 1312–1321.
    • (2011) Kidney Int , vol.79 , Issue.12 , pp. 1312-1321
    • Gilbert, R.E.1    Huang, Q.2    Thai, K.3    Advani, S.L.4    Lee, K.5    Yuen, D.A.6
  • 60
    • 53149097375 scopus 로고    scopus 로고
    • Effects of high-fat diet exposure during fetal life on type 2 diabetes development in the progeny
    • Gniuli, D., Calcagno, A., Caristo, M.E., Mancuso, A., Macchi, V., Mingrone, G., et al. Effects of high-fat diet exposure during fetal life on type 2 diabetes development in the progeny. J. Lipid Res 49:9 (2008), 1936–1945.
    • (2008) J. Lipid Res , vol.49 , Issue.9 , pp. 1936-1945
    • Gniuli, D.1    Calcagno, A.2    Caristo, M.E.3    Mancuso, A.4    Macchi, V.5    Mingrone, G.6
  • 61
    • 84877270825 scopus 로고    scopus 로고
    • NADPH oxidase 1 plays a key role in diabetes mellitus–accelerated atherosclerosis
    • Gray, S.P., Di Marco, E., Okabe, J., Szyndralewiez, C., Heitz, F., Montezano, A.C., et al. NADPH oxidase 1 plays a key role in diabetes mellitus–accelerated atherosclerosis. Circulation 127:18 (2013), 1888–1902.
    • (2013) Circulation , vol.127 , Issue.18 , pp. 1888-1902
    • Gray, S.P.1    Di Marco, E.2    Okabe, J.3    Szyndralewiez, C.4    Heitz, F.5    Montezano, A.C.6
  • 62
    • 84895490091 scopus 로고    scopus 로고
    • Arginine methylation of CRTC2 is critical in the transcriptional control of hepatic glucose metabolism
    • Han, H.-S., Jung, C.-Y., Yoon, Y.-S., Choi, S., Choi, D., Kang, G., et al. Arginine methylation of CRTC2 is critical in the transcriptional control of hepatic glucose metabolism. Sci. Signal, 7(314), 2014, ra19.
    • (2014) Sci. Signal , vol.7 , Issue.314 , pp. ra19
    • Han, H.-S.1    Jung, C.-Y.2    Yoon, Y.-S.3    Choi, S.4    Choi, D.5    Kang, G.6
  • 65
    • 85032038344 scopus 로고    scopus 로고
    • Nutrient regulation of signaling and transcription by O-GlcNAcylation
    • Hart, G.W., Nutrient regulation of signaling and transcription by O-GlcNAcylation. FASEB J. 29:1 (2015), Supp–489.3.
    • (2015) FASEB J. , vol.29 , Issue.1 , pp. Supp-489.3
    • Hart, G.W.1
  • 66
    • 0034114680 scopus 로고    scopus 로고
    • High-glucose-induced nuclear factor kB activation in vascular smooth muscle cells
    • Hattori, Y., Hattori, S., Sato, N., Kasai, K., High-glucose-induced nuclear factor kB activation in vascular smooth muscle cells. Cardiovasc. Res 46 (2000), 188–197.
    • (2000) Cardiovasc. Res , vol.46 , pp. 188-197
    • Hattori, Y.1    Hattori, S.2    Sato, N.3    Kasai, K.4
  • 67
    • 77952288176 scopus 로고    scopus 로고
    • Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice
    • Hayashida, S., Arimoto, A., Kuramoto, Y., Kozako, T., Honda, S., Shimeno, H., et al. Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice. Mol. Cell. Biochem 339:1–2 (2010), 285–292.
    • (2010) Mol. Cell. Biochem , vol.339 , Issue.1-2 , pp. 285-292
    • Hayashida, S.1    Arimoto, A.2    Kuramoto, Y.3    Kozako, T.4    Honda, S.5    Shimeno, H.6
  • 68
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-Carboxylcytosine and its excision by TDG in mammalian DNA
    • He, Y.-F., Li, B.-Z., Li, Z., Liu, P., Wang, Y., Tang, Q., et al. Tet-mediated formation of 5-Carboxylcytosine and its excision by TDG in mammalian DNA. Science 333:6047 (2011), 1303–1307.
    • (2011) Science , vol.333 , Issue.6047 , pp. 1303-1307
    • He, Y.-F.1    Li, B.-Z.2    Li, Z.3    Liu, P.4    Wang, Y.5    Tang, Q.6
  • 69
    • 33847334699 scopus 로고    scopus 로고
    • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
    • Heintzman, N.D., Stuart, R.K., Hon, G., Fu, Y., Ching, C.W., Hawkins, R.D., et al. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat. Genet 39:3 (2007), 311–318.
    • (2007) Nat. Genet , vol.39 , Issue.3 , pp. 311-318
    • Heintzman, N.D.1    Stuart, R.K.2    Hon, G.3    Fu, Y.4    Ching, C.W.5    Hawkins, R.D.6
  • 70
    • 84924346117 scopus 로고    scopus 로고
    • Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates
    • Hillman, S.L., Finer, S., Smart, M.C., Mathews, C., Lowe, R., Rakyan, V.K., et al. Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates. Epigenetics 10:1 (2015), 50–61.
    • (2015) Epigenetics , vol.10 , Issue.1 , pp. 50-61
    • Hillman, S.L.1    Finer, S.2    Smart, M.C.3    Mathews, C.4    Lowe, R.5    Rakyan, V.K.6
  • 72
    • 82455212901 scopus 로고    scopus 로고
    • SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
    • Hirschey, M.D., Shimazu, T., Jing, E., Grueter, C., Collins, A.M., Aouizerat, B., et al. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol. Cell 44:2 (2011), 177–190.
    • (2011) Mol. Cell , vol.44 , Issue.2 , pp. 177-190
    • Hirschey, M.D.1    Shimazu, T.2    Jing, E.3    Grueter, C.4    Collins, A.M.5    Aouizerat, B.6
  • 73
    • 53749096863 scopus 로고    scopus 로고
    • 10-year follow-up of intensive glucose control in type 2 diabetes
    • Holam, R.R., Paul, S.K., Bethel, A., Matthews, D.R., Neil, A.W., 10-year follow-up of intensive glucose control in type 2 diabetes. N. Engl. J. Med 359 (2008), 1577–1589.
    • (2008) N. Engl. J. Med , vol.359 , pp. 1577-1589
    • Holam, R.R.1    Paul, S.K.2    Bethel, A.3    Matthews, D.R.4    Neil, A.W.5
  • 74
    • 84978919885 scopus 로고    scopus 로고
    • Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice
    • Holland, M., Lowe, R., Caton, P., Gemma, C., Carbajosa, G., Danson, A., et al. Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice. Science 353:6298 (2016), 495–498.
    • (2016) Science , vol.353 , Issue.6298 , pp. 495-498
    • Holland, M.1    Lowe, R.2    Caton, P.3    Gemma, C.4    Carbajosa, G.5    Danson, A.6
  • 75
    • 79957572693 scopus 로고    scopus 로고
    • ADP-ribosylation of histones by ARTD1: an additional module of the histone code?
    • Hottiger, M.O., ADP-ribosylation of histones by ARTD1: an additional module of the histone code?. FEBS Lett 585:11 (2011), 1595–1599.
    • (2011) FEBS Lett , vol.585 , Issue.11 , pp. 1595-1599
    • Hottiger, M.O.1
  • 76
    • 84934272832 scopus 로고    scopus 로고
    • Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women
    • Houde, A.-A., Légaré, C., Biron, S., Lescelleur, O., Biertho, L., Marceau, S., et al. Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women. BMC Med. Genet 16:1 (2015), 1–10.
    • (2015) BMC Med. Genet , vol.16 , Issue.1 , pp. 1-10
    • Houde, A.-A.1    Légaré, C.2    Biron, S.3    Lescelleur, O.4    Biertho, L.5    Marceau, S.6
  • 77
    • 61749088806 scopus 로고    scopus 로고
    • Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
    • Huang, B., Yang, X.D., Zhou, M.M., Ozato, K., Chen, L.F., Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Mol. Cell. Biol 29:5 (2009), 1375–1387.
    • (2009) Mol. Cell. Biol , vol.29 , Issue.5 , pp. 1375-1387
    • Huang, B.1    Yang, X.D.2    Zhou, M.M.3    Ozato, K.4    Chen, L.F.5
  • 78
    • 34249934468 scopus 로고    scopus 로고
    • Reactive oxygen species mediate a cellular ‘memory’ of high glucose stress signalling
    • Ihnat, M.A., Thorpe, J.E., Kamat, C.D., Szabo, C., Green, D.E., Warnke, L.A., et al. Reactive oxygen species mediate a cellular ‘memory’ of high glucose stress signalling. Diabetologia 50:7 (2007), 1523–1531.
    • (2007) Diabetologia , vol.50 , Issue.7 , pp. 1523-1531
    • Ihnat, M.A.1    Thorpe, J.E.2    Kamat, C.D.3    Szabo, C.4    Green, D.E.5    Warnke, L.A.6
  • 79
    • 59149084125 scopus 로고    scopus 로고
    • Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes
    • Ijaz, A., Tejada, T., Catanuto, P., Xia, X., Elliot, S.J., Lenz, O., et al. Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes. Kidney Int 75:4 (2009), 381–388.
    • (2009) Kidney Int , vol.75 , Issue.4 , pp. 381-388
    • Ijaz, A.1    Tejada, T.2    Catanuto, P.3    Xia, X.4    Elliot, S.J.5    Lenz, O.6
  • 80
    • 68049095260 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
    • Inagaki, T., Tachibana, M., Magoori, K., Kudo, H., Tanaka, T., Okamura, M., et al. Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes Cells 14:8 (2009), 991–1001.
    • (2009) Genes Cells , vol.14 , Issue.8 , pp. 991-1001
    • Inagaki, T.1    Tachibana, M.2    Magoori, K.3    Kudo, H.4    Tanaka, T.5    Okamura, M.6
  • 81
    • 84922769734 scopus 로고    scopus 로고
    • The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis
    • Inagaki, T., Iwasaki, S., Matsumura, Y., Kawamura, T., Tanaka, T., Abe, Y., et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J. Biol. Chem 290:7 (2015), 4163–4177.
    • (2015) J. Biol. Chem , vol.290 , Issue.7 , pp. 4163-4177
    • Inagaki, T.1    Iwasaki, S.2    Matsumura, Y.3    Kawamura, T.4    Tanaka, T.5    Abe, Y.6
  • 82
    • 84866300710 scopus 로고    scopus 로고
    • Reduced histone H3K9 acetylation of clock genes and abnormal glucose metabolism in ob/ob mice
    • Ishikawa-Kobayashi, E., Ushijima, K., Ando, H., Maekawa, T., Takuma, M., Furukawa, Y., et al. Reduced histone H3K9 acetylation of clock genes and abnormal glucose metabolism in ob/ob mice. Chronobiol. Int 29:8 (2012), 982–993.
    • (2012) Chronobiol. Int , vol.29 , Issue.8 , pp. 982-993
    • Ishikawa-Kobayashi, E.1    Ushijima, K.2    Ando, H.3    Maekawa, T.4    Takuma, M.5    Furukawa, Y.6
  • 84
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein, T., Allis, C.D., Translating the histone code. Science 293:5532 (2001), 1074–1080.
    • (2001) Science , vol.293 , Issue.5532 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 85
    • 84901835198 scopus 로고    scopus 로고
    • Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy
    • Jha, J.C., Gray, S.P., Barit, D., Okabe, J., El-Osta, A., Namikoshi, T., et al. Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy. J. Am. Soc. Nephrol 25:6 (2014), 1237–1254.
    • (2014) J. Am. Soc. Nephrol , vol.25 , Issue.6 , pp. 1237-1254
    • Jha, J.C.1    Gray, S.P.2    Barit, D.3    Okabe, J.4    El-Osta, A.5    Namikoshi, T.6
  • 86
    • 69949172827 scopus 로고    scopus 로고
    • HAT–HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress
    • Johnsson, A., Durand-Dubief, M., Xue-Franzén, Y., Rönnerblad, M., Ekwall, K., Wright, A., HAT–HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress. EMBO Rep 10:9 (2009), 1009–1014.
    • (2009) EMBO Rep , vol.10 , Issue.9 , pp. 1009-1014
    • Johnsson, A.1    Durand-Dubief, M.2    Xue-Franzén, Y.3    Rönnerblad, M.4    Ekwall, K.5    Wright, A.6
  • 87
    • 84875755814 scopus 로고    scopus 로고
    • Influence of metabolism on epigenetics and disease
    • Kaelin, W.G. Jr., McKnight, S.L., Influence of metabolism on epigenetics and disease. Cell 153:1 (2013), 56–69.
    • (2013) Cell , vol.153 , Issue.1 , pp. 56-69
    • Kaelin, W.G.1    McKnight, S.L.2
  • 88
    • 79953796491 scopus 로고    scopus 로고
    • Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner
    • Kanamaluru, D., Xiao, Z., Fang, S., Choi, S.-E., Kim, D.-H., Veenstra, T.D., et al. Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner. Mol. Cell. Biol 31:7 (2011), 1540–1550.
    • (2011) Mol. Cell. Biol , vol.31 , Issue.7 , pp. 1540-1550
    • Kanamaluru, D.1    Xiao, Z.2    Fang, S.3    Choi, S.-E.4    Kim, D.-H.5    Veenstra, T.D.6
  • 89
    • 77953244349 scopus 로고    scopus 로고
    • SIRT6 protects against pathological damage caused by diet-induced obesity
    • Kanfi, Y., Peshti, V., Gil, R., Naiman, S., Nahum, L., Levin, E., et al. SIRT6 protects against pathological damage caused by diet-induced obesity. Aging Cell 9:2 (2010), 162–173.
    • (2010) Aging Cell , vol.9 , Issue.2 , pp. 162-173
    • Kanfi, Y.1    Peshti, V.2    Gil, R.3    Naiman, S.4    Nahum, L.5    Levin, E.6
  • 90
    • 84926161089 scopus 로고    scopus 로고
    • Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis
    • Kang, S., Tsai, L.T., Zhou, Y., Evertts, A., Xu, S., Griffin, M.J., et al. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nat. Cell Biol 17:1 (2015), 44–56.
    • (2015) Nat. Cell Biol , vol.17 , Issue.1 , pp. 44-56
    • Kang, S.1    Tsai, L.T.2    Zhou, Y.3    Evertts, A.4    Xu, S.5    Griffin, M.J.6
  • 91
    • 70349573301 scopus 로고    scopus 로고
    • DNA methylation and gene expression differences in children conceived in vitro or in vivo
    • Katari, S., Turan, N., Bibikova, M., Erinle, O., Chalian, R., Foster, M., et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum. Mol. Genet 18:20 (2009), 3769–3778.
    • (2009) Hum. Mol. Genet , vol.18 , Issue.20 , pp. 3769-3778
    • Katari, S.1    Turan, N.2    Bibikova, M.3    Erinle, O.4    Chalian, R.5    Foster, M.6
  • 92
    • 33845524077 scopus 로고    scopus 로고
    • Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300
    • Kaur, H., Chen, S., Xin, X., Chiu, J., Khan, Z.A., Chakrabarti, S., Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300. Diabetes 55:11 (2006), 3104–3111.
    • (2006) Diabetes , vol.55 , Issue.11 , pp. 3104-3111
    • Kaur, H.1    Chen, S.2    Xin, X.3    Chiu, J.4    Khan, Z.A.5    Chakrabarti, S.6
  • 93
    • 84929045419 scopus 로고    scopus 로고
    • Transcriptional regulation by the Set7 lysine methyltransferase
    • Keating, S., El-Osta, A., Transcriptional regulation by the Set7 lysine methyltransferase. Epigenetics 8:4 (2013), 361–372.
    • (2013) Epigenetics , vol.8 , Issue.4 , pp. 361-372
    • Keating, S.1    El-Osta, A.2
  • 94
    • 84879796488 scopus 로고    scopus 로고
    • Epigenetic changes in diabetes
    • Keating, S.T., El-Osta, A., Epigenetic changes in diabetes. Clin. Genet 84 (2013), 1–10.
    • (2013) Clin. Genet , vol.84 , pp. 1-10
    • Keating, S.T.1    El-Osta, A.2
  • 95
    • 84924181684 scopus 로고    scopus 로고
    • Epigenetics and metabolism
    • Keating, S.T., El-Osta, A., Epigenetics and metabolism. Circ. Res 116:4 (2015), 715–736.
    • (2015) Circ. Res , vol.116 , Issue.4 , pp. 715-736
    • Keating, S.T.1    El-Osta, A.2
  • 97
    • 70350606061 scopus 로고    scopus 로고
    • FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states
    • Kemper, J.K., Xiao, Z., Ponugoti, B., Miao, J., Fang, S., Kanamaluru, D., et al. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metab 10:5 (2009), 392–404.
    • (2009) Cell Metab , vol.10 , Issue.5 , pp. 392-404
    • Kemper, J.K.1    Xiao, Z.2    Ponugoti, B.3    Miao, J.4    Fang, S.5    Kanamaluru, D.6
  • 98
    • 84976333826 scopus 로고    scopus 로고
    • DNA methylation regulates hypothalamic gene expression linking parental diet during pregnancy to the offspring's rick of obesity in Psammomys obesus
    • Khurana, I., Kaspi, A., Ziemann, M., Block, T., Connor, T., Spolding, B., et al. DNA methylation regulates hypothalamic gene expression linking parental diet during pregnancy to the offspring's rick of obesity in Psammomys obesus. Int. J. Obes 40:7 (2016), 1079–1088.
    • (2016) Int. J. Obes , vol.40 , Issue.7 , pp. 1079-1088
    • Khurana, I.1    Kaspi, A.2    Ziemann, M.3    Block, T.4    Connor, T.5    Spolding, B.6
  • 99
    • 85015265776 scopus 로고    scopus 로고
    • Influence of amino acid metabolism on embryonic stem cell function and differentiation
    • Kilberg, M.S., Terada, N., Shan, J., Influence of amino acid metabolism on embryonic stem cell function and differentiation. Adv. Nutr 7:4 (2016), 780S–789S.
    • (2016) Adv. Nutr , vol.7 , Issue.4 , pp. 780S-789S
    • Kilberg, M.S.1    Terada, N.2    Shan, J.3
  • 100
    • 84947474496 scopus 로고    scopus 로고
    • PRMT1 and PRMT4 regulate oxidative stress-induced retinal pigment epithelial cell damage in SIRT1-dependent and SIRT1-independent manners
    • Kim, D.-I., Park, M.-J., Choi, J.-H., Kim, I.-S., Han, H.-J., Yoon, K.-C., et al. PRMT1 and PRMT4 regulate oxidative stress-induced retinal pigment epithelial cell damage in SIRT1-dependent and SIRT1-independent manners. Oxid. Med. Cell. Longev, 2015, 2015, 617919.
    • (2015) Oxid. Med. Cell. Longev , vol.2015 , pp. 617919
    • Kim, D.-I.1    Park, M.-J.2    Choi, J.-H.3    Kim, I.-S.4    Han, H.-J.5    Yoon, K.-C.6
  • 101
    • 41949120723 scopus 로고    scopus 로고
    • Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
    • Knutson, S.K., Chyla, B.J., Amann, J.M., Bhaskara, S., Huppert, S.S., Hiebert, S.W., Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. EMBO J. 27:7 (2008), 1017–1028.
    • (2008) EMBO J. , vol.27 , Issue.7 , pp. 1017-1028
    • Knutson, S.K.1    Chyla, B.J.2    Amann, J.M.3    Bhaskara, S.4    Huppert, S.S.5    Hiebert, S.W.6
  • 102
    • 33745173485 scopus 로고    scopus 로고
    • Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy
    • Kong, Y., Tannous, P., Lu, G., Berenji, K., Rothermel, B.A., Olson, E.N., et al. Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 113:22 (2006), 2579–2588.
    • (2006) Circulation , vol.113 , Issue.22 , pp. 2579-2588
    • Kong, Y.1    Tannous, P.2    Lu, G.3    Berenji, K.4    Rothermel, B.A.5    Olson, E.N.6
  • 103
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides, T., Chromatin modifications and their function. Cell 128 (2007), 693–705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 104
    • 85032041408 scopus 로고    scopus 로고
    • Role of H3K36me2 in palmitate induced metabolic memory in human podocytes
    • Kumar, S., Tikoo, K., Role of H3K36me2 in palmitate induced metabolic memory in human podocytes. FASEB J., 29, 2015, 877.6.
    • (2015) FASEB J. , vol.29 , pp. 877.6
    • Kumar, S.1    Tikoo, K.2
  • 106
    • 84914141395 scopus 로고    scopus 로고
    • Inactivation of histone deacetylase 1 (HDAC1) but not HDAC2 is required for the glucocorticoid-dependent CCAAT/enhancer-binding protein α (C/EBPα) expression and preadipocyte differentiation
    • Kuzmochka, C., Abdou, H.-S., Haché, R.J.G., Atlas, E., Inactivation of histone deacetylase 1 (HDAC1) but not HDAC2 is required for the glucocorticoid-dependent CCAAT/enhancer-binding protein α (C/EBPα) expression and preadipocyte differentiation. Endocrinology 155:12 (2014), 4762–4773.
    • (2014) Endocrinology , vol.155 , Issue.12 , pp. 4762-4773
    • Kuzmochka, C.1    Abdou, H.-S.2    Haché, R.J.G.3    Atlas, E.4
  • 107
    • 34547431097 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: a novel class of therapeutic agents in diabetic nephropathy
    • Lee, H.B., Noh, H., Seo, J.Y., Yu, M.R., Ha, H., Histone deacetylase inhibitors: a novel class of therapeutic agents in diabetic nephropathy. Kidney Int 72 (2007), S61–S66.
    • (2007) Kidney Int , vol.72 , pp. S61-S66
    • Lee, H.B.1    Noh, H.2    Seo, J.Y.3    Yu, M.R.4    Ha, H.5
  • 108
    • 58049206724 scopus 로고    scopus 로고
    • Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
    • Lee, J., Saha, P.K., Yang, Q.-H., Lee, S., Park, J.Y., Suh, Y., et al. Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc. Natl. Acad. Sci. U.S.A. 105:49 (2008), 19229–19234.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , Issue.49 , pp. 19229-19234
    • Lee, J.1    Saha, P.K.2    Yang, Q.-H.3    Lee, S.4    Park, J.Y.5    Suh, Y.6
  • 109
    • 84905816638 scopus 로고    scopus 로고
    • Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation
    • Lee, J., Carrer, A., Shah, S., Snyder, N.W., Wei, S., Venneti, S., et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metab 20:2 (2014), 306–319.
    • (2014) Cell Metab , vol.20 , Issue.2 , pp. 306-319
    • Lee, J.1    Carrer, A.2    Shah, S.3    Snyder, N.W.4    Wei, S.5    Venneti, S.6
  • 110
    • 44649177124 scopus 로고    scopus 로고
    • Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors
    • Lee, S., Lee, J., Lee, S.-K., Lee, J.W., Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors. Mol. Endocrinol 22:6 (2008), 1312–1319.
    • (2008) Mol. Endocrinol , vol.22 , Issue.6 , pp. 1312-1319
    • Lee, S.1    Lee, J.2    Lee, S.-K.3    Lee, J.W.4
  • 111
    • 80755168896 scopus 로고    scopus 로고
    • Specific Control of Pancreatic Endocrine β and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9
    • Lenoir, O., Flosseau, K., Xia Ma, F., Blondeau, B., Mai, A., Bassel-Duby, R., et al. Specific Control of Pancreatic Endocrine β and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9. Diabetes 60 (2011), 2861–2871.
    • (2011) Diabetes , vol.60 , pp. 2861-2871
    • Lenoir, O.1    Flosseau, K.2    Xia Ma, F.3    Blondeau, B.4    Mai, A.5    Bassel-Duby, R.6
  • 112
    • 33744534726 scopus 로고    scopus 로고
    • GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha
    • Lerin, C., Rodgers, J.T., Kalume, D.E., Kim, S.H., Pandey, A., Puigserver, P., GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab 3:6 (2006), 429–438.
    • (2006) Cell Metab , vol.3 , Issue.6 , pp. 429-438
    • Lerin, C.1    Rodgers, J.T.2    Kalume, D.E.3    Kim, S.H.4    Pandey, A.5    Puigserver, P.6
  • 113
    • 84880792943 scopus 로고    scopus 로고
    • Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells
    • Leung, A., Trac, C., Jin, W., Lanting, L., Akbany, A., Saetrom, P., et al. Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells. Circ. Res 113:3 (2013), 266–278.
    • (2013) Circ. Res , vol.113 , Issue.3 , pp. 266-278
    • Leung, A.1    Trac, C.2    Jin, W.3    Lanting, L.4    Akbany, A.5    Saetrom, P.6
  • 114
    • 79957949655 scopus 로고    scopus 로고
    • The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro
    • Lewis, E.C., Blaabjerg, L., Størling, J., Ronn, S.G., Mascagni, P., Dinarello, C.A., et al. The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro. Mol. Med 17:5–6 (2011), 369–377.
    • (2011) Mol. Med , vol.17 , Issue.5-6 , pp. 369-377
    • Lewis, E.C.1    Blaabjerg, L.2    Størling, J.3    Ronn, S.G.4    Mascagni, P.5    Dinarello, C.A.6
  • 115
    • 84901397700 scopus 로고    scopus 로고
    • ADP-ribosylation: activation, recognition, and removal
    • Li, N., Chen, J., ADP-ribosylation: activation, recognition, and removal. Mol. Cells 37:1 (2014), 9–16.
    • (2014) Mol. Cells , vol.37 , Issue.1 , pp. 9-16
    • Li, N.1    Chen, J.2
  • 116
    • 84947739751 scopus 로고    scopus 로고
    • Serine and SAM responsive complex SESAME regulates histone modification crosstalk by sensing cellular metabolism
    • Li, S., Swanson, S.K., Gogol, M., Florens, L., Washburn, M.P., Workman, J.L., et al. Serine and SAM responsive complex SESAME regulates histone modification crosstalk by sensing cellular metabolism. Mol. Cell 60:3 (2015), 408–421.
    • (2015) Mol. Cell , vol.60 , Issue.3 , pp. 408-421
    • Li, S.1    Swanson, S.K.2    Gogol, M.3    Florens, L.4    Washburn, M.P.5    Workman, J.L.6
  • 118
    • 55549140173 scopus 로고    scopus 로고
    • Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-κB-dependent inflammatory genes: relevance to diabetes and inflammation
    • Li, Y., Reddy, M.A., Miao, F., Shanmugam, N., Yee, J.-K., Hawkins, D., et al. Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-κB-dependent inflammatory genes: relevance to diabetes and inflammation. J. Biol. Chem 283 (2008), 26771–26781.
    • (2008) J. Biol. Chem , vol.283 , pp. 26771-26781
    • Li, Y.1    Reddy, M.A.2    Miao, F.3    Shanmugam, N.4    Yee, J.-K.5    Hawkins, D.6
  • 119
    • 36049002392 scopus 로고    scopus 로고
    • Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle
    • Ling, C., Poulsen, P., Simonsson, S., Rönn, T., Holmkvist, J., Almgren, P., et al. Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle. J. Clin. Invest 117:11 (2007), 3427–3435.
    • (2007) J. Clin. Invest , vol.117 , Issue.11 , pp. 3427-3435
    • Ling, C.1    Poulsen, P.2    Simonsson, S.3    Rönn, T.4    Holmkvist, J.5    Almgren, P.6
  • 120
    • 84931281665 scopus 로고    scopus 로고
    • Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
    • Liu, X., Chen, Z., Xu, C., Leng, X., Cao, H., Ouyang, G., et al. Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation. Nucleic Acids Res 43:10 (2015), 5081–5098.
    • (2015) Nucleic Acids Res , vol.43 , Issue.10 , pp. 5081-5098
    • Liu, X.1    Chen, Z.2    Xu, C.3    Leng, X.4    Cao, H.5    Ouyang, G.6
  • 121
    • 84924272203 scopus 로고    scopus 로고
    • Glycolytic metabolism influences global chromatin structure
    • Liu, X.-S., Little, J.B., Yuan, Z.-M., Glycolytic metabolism influences global chromatin structure. Oncotarget 6:6 (2015), 4214–4225.
    • (2015) Oncotarget , vol.6 , Issue.6 , pp. 4214-4225
    • Liu, X.-S.1    Little, J.B.2    Yuan, Z.-M.3
  • 122
    • 79954508354 scopus 로고    scopus 로고
    • NF-κB activation in organs from STZ-treated rats
    • Locke, M., Anderson, J., NF-κB activation in organs from STZ-treated rats. Appl. Physiol. Nutr. Metab 36 (2011), 121–127.
    • (2011) Appl. Physiol. Nutr. Metab , vol.36 , pp. 121-127
    • Locke, M.1    Anderson, J.2
  • 123
    • 78650864017 scopus 로고    scopus 로고
    • Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
    • Loenarz, C., Schofield, C.J., Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases. Trends Biochem. Sci 36:1 (2011), 7–18.
    • (2011) Trends Biochem. Sci , vol.36 , Issue.1 , pp. 7-18
    • Loenarz, C.1    Schofield, C.J.2
  • 124
    • 78649516570 scopus 로고    scopus 로고
    • The coactivator SRC-1 is an essential coordinator of hepatic glucose production
    • Louet, J.-F., Chopra, A.R., Sagen, J.V., An, J., York, B., Tannour-Louet, M., et al. The coactivator SRC-1 is an essential coordinator of hepatic glucose production. Cell Metab 12:6 (2010), 606–618.
    • (2010) Cell Metab , vol.12 , Issue.6 , pp. 606-618
    • Louet, J.-F.1    Chopra, A.R.2    Sagen, J.V.3    An, J.4    York, B.5    Tannour-Louet, M.6
  • 125
    • 67449161568 scopus 로고    scopus 로고
    • Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy
    • Lu, T.C., Wang, Z.-H., Feng, X., Chuang, P.Y., Fang, W., Shen, Y., et al. Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy. Kidney Int 76:1 (2009), 63–71.
    • (2009) Kidney Int , vol.76 , Issue.1 , pp. 63-71
    • Lu, T.C.1    Wang, Z.-H.2    Feng, X.3    Chuang, P.Y.4    Fang, W.5    Shen, Y.6
  • 126
    • 84927145879 scopus 로고    scopus 로고
    • Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9
    • Maganti, A.V., Maier, B., Tersey, S.A., Sampley, M.L., Mosley, A.L., Özcan, S., et al. Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J. Biol. Chem 290:15 (2015), 9812–9822.
    • (2015) J. Biol. Chem , vol.290 , Issue.15 , pp. 9812-9822
    • Maganti, A.V.1    Maier, B.2    Tersey, S.A.3    Sampley, M.L.4    Mosley, A.L.5    Özcan, S.6
  • 127
    • 84946067197 scopus 로고    scopus 로고
    • O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice
    • Makino, A., Dai, A., Han, Y., Youssef, K.D., Wang, W., Donthamsetty, R., et al. O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice. Am. J. Physiol. Cell Physiol 309:9 (2015), C593–C599.
    • (2015) Am. J. Physiol. Cell Physiol , vol.309 , Issue.9 , pp. C593-C599
    • Makino, A.1    Dai, A.2    Han, Y.3    Youssef, K.D.4    Wang, W.5    Donthamsetty, R.6
  • 128
    • 84876934840 scopus 로고    scopus 로고
    • Coordinate changes in histone modifications, mRNA levels, and metabolite profiles in clonal INS-1 832/13 beta-cells accompany functional adaptations to lipotoxicity
    • Malmgren, S., Spegel, P., Danielsson, A.P., Nagorny, C.L., Andersson, L.E., Nitert, M.D., et al. Coordinate changes in histone modifications, mRNA levels, and metabolite profiles in clonal INS-1 832/13 beta-cells accompany functional adaptations to lipotoxicity. J. Biol. Chem 288:17 (2013), 11973–11987.
    • (2013) J. Biol. Chem , vol.288 , Issue.17 , pp. 11973-11987
    • Malmgren, S.1    Spegel, P.2    Danielsson, A.P.3    Nagorny, C.L.4    Andersson, L.E.5    Nitert, M.D.6
  • 129
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • Martin, C., Zhang, Y., The diverse functions of histone lysine methylation. Nat. Rev. Mol. Cell Biol 6:11 (2005), 838–849.
    • (2005) Nat. Rev. Mol. Cell Biol , vol.6 , Issue.11 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 130
    • 42449161465 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5
    • McGee, S.L., van Denderen, B.J., Howlett, K.F., Mollica, J., Schertzer, J.D., Kemp, B.E., et al. AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5. Diabetes 57:4 (2008), 860–867.
    • (2008) Diabetes , vol.57 , Issue.4 , pp. 860-867
    • McGee, S.L.1    van Denderen, B.J.2    Howlett, K.F.3    Mollica, J.4    Schertzer, J.D.5    Kemp, B.E.6
  • 131
    • 84948412126 scopus 로고    scopus 로고
    • Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
    • Mentch, S.J., Mehrmohamadi, M., Huang, L., Liu, X., Gupta, D., Mattocks, D., et al. Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism. Cell Metab 22:5 (2015), 861–873.
    • (2015) Cell Metab , vol.22 , Issue.5 , pp. 861-873
    • Mentch, S.J.1    Mehrmohamadi, M.2    Huang, L.3    Liu, X.4    Gupta, D.5    Mattocks, D.6
  • 133
    • 2342423022 scopus 로고    scopus 로고
    • In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions
    • Miao, F., Gonzalo, I.G., Lanting, L., Natarajan, R., In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J. Biol. Chem 279:17 (2004), 18091–18097.
    • (2004) J. Biol. Chem , vol.279 , Issue.17 , pp. 18091-18097
    • Miao, F.1    Gonzalo, I.G.2    Lanting, L.3    Natarajan, R.4
  • 134
    • 58149345088 scopus 로고    scopus 로고
    • Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes
    • Miao, F., Smith, D.D., Zhang, L., Min, A., Feng, W., Natarajan, R., Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes. Diabetes 57:12 (2008), 3189–3198.
    • (2008) Diabetes , vol.57 , Issue.12 , pp. 3189-3198
    • Miao, F.1    Smith, D.D.2    Zhang, L.3    Min, A.4    Feng, W.5    Natarajan, R.6
  • 135
    • 84897489404 scopus 로고    scopus 로고
    • Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes
    • Miao, F., Chen, Z., Genuth, S., Paterson, A., Zhang, L., Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes. Diabetes 63 (2014), 1748–1762.
    • (2014) Diabetes , vol.63 , pp. 1748-1762
    • Miao, F.1    Chen, Z.2    Genuth, S.3    Paterson, A.4    Zhang, L.5
  • 136
    • 79955815135 scopus 로고    scopus 로고
    • Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis
    • Mihaylova, M.M., Vasquez, D.S., Ravnskjaer, K., Denechaud, P.-D., Yu, R.T., Alvarez, J.G., et al. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell 145:4 (2011), 607–621.
    • (2011) Cell , vol.145 , Issue.4 , pp. 607-621
    • Mihaylova, M.M.1    Vasquez, D.S.2    Ravnskjaer, K.3    Denechaud, P.-D.4    Yu, R.T.5    Alvarez, J.G.6
  • 137
    • 33645745733 scopus 로고    scopus 로고
    • Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
    • Monnier, L.M., Mas, E., Ginet, C., Michel, F., Villon, L., Cristol, J.P., et al. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 295:14 (2006), 1681–1687.
    • (2006) JAMA , vol.295 , Issue.14 , pp. 1681-1687
    • Monnier, L.M.1    Mas, E.2    Ginet, C.3    Michel, F.4    Villon, L.5    Cristol, J.P.6
  • 138
    • 0038820063 scopus 로고    scopus 로고
    • Glucose regulates insulin gene transcription by hyperacetylation of histone H4
    • Mosley, A.L., Ozcan, S., Glucose regulates insulin gene transcription by hyperacetylation of histone H4. J. Biol. Chem 278:22 (2003), 19660–19666.
    • (2003) J. Biol. Chem , vol.278 , Issue.22 , pp. 19660-19666
    • Mosley, A.L.1    Ozcan, S.2
  • 139
    • 11144237178 scopus 로고    scopus 로고
    • The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose
    • Mosley, A.L., Ozcan, S., The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose. J. Biol. Chem 279:52 (2004), 54241–54247.
    • (2004) J. Biol. Chem , vol.279 , Issue.52 , pp. 54241-54247
    • Mosley, A.L.1    Ozcan, S.2
  • 140
    • 4544233448 scopus 로고    scopus 로고
    • Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1
    • Mosley, A.L., Corbett, J.A., Ozcan, S., Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. Mol. Endocrinol 18:9 (2004), 2279–2290.
    • (2004) Mol. Endocrinol , vol.18 , Issue.9 , pp. 2279-2290
    • Mosley, A.L.1    Corbett, J.A.2    Ozcan, S.3
  • 141
    • 63349088398 scopus 로고    scopus 로고
    • The oxidative stress of hyperglycemia and the inflammatory process in endothelial cells
    • Muniandy, S.Q., Qvist, R., Yan, G.O., Bee, C.J., Chu, Y.K., Rayappan, A.V., The oxidative stress of hyperglycemia and the inflammatory process in endothelial cells. J. Med. Invest 56 (2009), 6–10.
    • (2009) J. Med. Invest , vol.56 , pp. 6-10
    • Muniandy, S.Q.1    Qvist, R.2    Yan, G.O.3    Bee, C.J.4    Chu, Y.K.5    Rayappan, A.V.6
  • 143
    • 84924853594 scopus 로고    scopus 로고
    • Lysine-specific demethylase 2 suppresses lipid influx and metabolism in hepatic cells
    • Nagaoka, K., Hino, S., Sakamoto, A., Anan, K., Takase, R., Umehara, T., et al. Lysine-specific demethylase 2 suppresses lipid influx and metabolism in hepatic cells. Mol. Cell. Biol 35:7 (2015), 1068–1080.
    • (2015) Mol. Cell. Biol , vol.35 , Issue.7 , pp. 1068-1080
    • Nagaoka, K.1    Hino, S.2    Sakamoto, A.3    Anan, K.4    Takase, R.5    Umehara, T.6
  • 144
    • 47549088250 scopus 로고    scopus 로고
    • The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
    • Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D., et al. The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 134:2 (2008), 329–340.
    • (2008) Cell , vol.134 , Issue.2 , pp. 329-340
    • Nakahata, Y.1    Kaluzova, M.2    Grimaldi, B.3    Sahar, S.4    Hirayama, J.5    Chen, D.6
  • 145
    • 77958596171 scopus 로고    scopus 로고
    • Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring
    • Ng, S.F., Lin, R.C.Y., Laybutt, D.R., Barres, R., Owens, J.A., Morris, M.J., Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature 467:7318 (2010), 963–966.
    • (2010) Nature , vol.467 , Issue.7318 , pp. 963-966
    • Ng, S.F.1    Lin, R.C.Y.2    Laybutt, D.R.3    Barres, R.4    Owens, J.A.5    Morris, M.J.6
  • 146
    • 78650806593 scopus 로고    scopus 로고
    • Suppression of inflammation by a synthetic histone mimic
    • Nicodeme, E., Jeffrey, K.L., Schaefer, U., Beinke, S., Dewell, S., Chung, C.W., et al. Suppression of inflammation by a synthetic histone mimic. Nature 468:7327 (2010), 1119–1123.
    • (2010) Nature , vol.468 , Issue.7327 , pp. 1119-1123
    • Nicodeme, E.1    Jeffrey, K.L.2    Schaefer, U.3    Beinke, S.4    Dewell, S.5    Chung, C.W.6
  • 147
    • 84906707442 scopus 로고    scopus 로고
    • Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes
    • Nilsson, E., Jansson, P.A., Perfilyev, A., Volkov, P., Pedersen, M., Svensson, M.K., et al. Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes. Diabetes 63:9 (2014), 2962–2976.
    • (2014) Diabetes , vol.63 , Issue.9 , pp. 2962-2976
    • Nilsson, E.1    Jansson, P.A.2    Perfilyev, A.3    Volkov, P.4    Pedersen, M.5    Svensson, M.K.6
  • 148
    • 84870319843 scopus 로고    scopus 로고
    • Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes
    • Nitert, M.D., Dayeh, T., Volkov, P., Elgzyri, T., Hall, E., Nilsson, E., et al. Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes. Diabetes, 61(12), 2012, 3322.
    • (2012) Diabetes , vol.61 , Issue.12 , pp. 3322
    • Nitert, M.D.1    Dayeh, T.2    Volkov, P.3    Elgzyri, T.4    Hall, E.5    Nilsson, E.6
  • 149
    • 69449107940 scopus 로고    scopus 로고
    • Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury
    • Noh, H., Oh, E.Y., Seo, J.Y., Yu, M.R., Kim, Y.O., Ha, H., et al. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury. Am. J. Physiol. Renal Physiol 297:3 (2009), F729–F739.
    • (2009) Am. J. Physiol. Renal Physiol , vol.297 , Issue.3 , pp. F729-F739
    • Noh, H.1    Oh, E.Y.2    Seo, J.Y.3    Yu, M.R.4    Kim, Y.O.5    Ha, H.6
  • 150
    • 84863393198 scopus 로고    scopus 로고
    • Distinguishing hyperglycemic changes by set7 in vascular endothelial cells
    • Okabe, J., Orlowski, C., Balcerczyk, A., Tikellis, C., Thomas, M.C., Cooper, M.E., et al. Distinguishing hyperglycemic changes by set7 in vascular endothelial cells. Circ. Res 110:8 (2012), 1067–1076.
    • (2012) Circ. Res , vol.110 , Issue.8 , pp. 1067-1076
    • Okabe, J.1    Orlowski, C.2    Balcerczyk, A.3    Tikellis, C.4    Thomas, M.C.5    Cooper, M.E.6
  • 151
    • 84905276064 scopus 로고    scopus 로고
    • Endothelial transcriptome in response to pharmacological methyltransferase inhibition
    • Okabe, J., Fernandez, A.Z., Ziemann, M., Keating, S.T., Balcerczyk, A., El-Osta, A., Endothelial transcriptome in response to pharmacological methyltransferase inhibition. Chem. Med. Chem 9:8 (2014), 1755–1762.
    • (2014) Chem. Med. Chem , vol.9 , Issue.8 , pp. 1755-1762
    • Okabe, J.1    Fernandez, A.Z.2    Ziemann, M.3    Keating, S.T.4    Balcerczyk, A.5    El-Osta, A.6
  • 152
    • 77953515715 scopus 로고    scopus 로고
    • Role of histone methylation and demethylation in adipogenesis and obesity
    • Okamura, M., Inagaki, T., Tanaka, T., Sakai, J., Role of histone methylation and demethylation in adipogenesis and obesity. Organogenesis 6:1 (2010), 24–32.
    • (2010) Organogenesis , vol.6 , Issue.1 , pp. 24-32
    • Okamura, M.1    Inagaki, T.2    Tanaka, T.3    Sakai, J.4
  • 153
    • 84954228583 scopus 로고    scopus 로고
    • HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes
    • Ooi, J.Y., Tuano, N.K., Rafehi, H., Gao, X.M., Ziemann, M., Du, X.J., et al. HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes. Epigenetics 10:5 (2015), 418–430.
    • (2015) Epigenetics , vol.10 , Issue.5 , pp. 418-430
    • Ooi, J.Y.1    Tuano, N.K.2    Rafehi, H.3    Gao, X.M.4    Ziemann, M.5    Du, X.J.6
  • 154
    • 84920918662 scopus 로고    scopus 로고
    • Paternal diet defines offspring chromatin state and intergenerational obesity
    • Öst, A., Lempradl, A., Casas, E., Weigert, M., Tiko, T., Deniz, M., et al. Paternal diet defines offspring chromatin state and intergenerational obesity. Cell 159:6 (2014), 1352–1364.
    • (2014) Cell , vol.159 , Issue.6 , pp. 1352-1364
    • Öst, A.1    Lempradl, A.2    Casas, E.3    Weigert, M.4    Tiko, T.5    Deniz, M.6
  • 155
    • 84864210978 scopus 로고    scopus 로고
    • Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes
    • Paneni, F., Mocharla, P., Akhmedov, A., Costantino, S., Osto, E., Volpe, M., et al. Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes. Circ. Res 111:3 (2012), 278–289.
    • (2012) Circ. Res , vol.111 , Issue.3 , pp. 278-289
    • Paneni, F.1    Mocharla, P.2    Akhmedov, A.3    Costantino, S.4    Osto, E.5    Volpe, M.6
  • 156
    • 84924627239 scopus 로고    scopus 로고
    • Adverse epigenetic signatures by histone methyltransferase set7 contribute to vascular dysfunction in patients with type 2 diabetes
    • Paneni, F., Costantino, S., Battista, R., Castello, L., Capretti, G., Chiandotto, S., et al. Adverse epigenetic signatures by histone methyltransferase set7 contribute to vascular dysfunction in patients with type 2 diabetes. Circ. Cardiovasc. Gene 8 (2015), 150–158.
    • (2015) Circ. Cardiovasc. Gene , vol.8 , pp. 150-158
    • Paneni, F.1    Costantino, S.2    Battista, R.3    Castello, L.4    Capretti, G.5    Chiandotto, S.6
  • 157
    • 70349636576 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy
    • Pang, M., Kothapally, J., Mao, H., Tolbert, E., Ponnusamy, M., Chin, Y.E., et al. Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. Am. J. Physiol. Renal Physiol 297:4 (2009), F996–F1005.
    • (2009) Am. J. Physiol. Renal Physiol , vol.297 , Issue.4 , pp. F996-F1005
    • Pang, M.1    Kothapally, J.2    Mao, H.3    Tolbert, E.4    Ponnusamy, M.5    Chin, Y.E.6
  • 158
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park, J.H., Stoffers, D.A., Nicholls, R.D., Simmons, R.A., Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J. Clin. Invest 118:6 (2008), 2316–2324.
    • (2008) J. Clin. Invest , vol.118 , Issue.6 , pp. 2316-2324
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 159
    • 77953366814 scopus 로고    scopus 로고
    • Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer
    • Peterson, C.W., Stoltzman, C.A., Sighinolfi, M.P., Han, K.S., Ayer, D.E., Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer. Mol. Cell. Biol 30:12 (2010), 2887–2895.
    • (2010) Mol. Cell. Biol , vol.30 , Issue.12 , pp. 2887-2895
    • Peterson, C.W.1    Stoltzman, C.A.2    Sighinolfi, M.P.3    Han, K.S.4    Ayer, D.E.5
  • 161
    • 84875709775 scopus 로고    scopus 로고
    • Bridging epigenetics and metabolism
    • Phang, J.M., Liu, W., Hancock, C., Bridging epigenetics and metabolism. Epigenetics 8:3 (2013), 231–236.
    • (2013) Epigenetics , vol.8 , Issue.3 , pp. 231-236
    • Phang, J.M.1    Liu, W.2    Hancock, C.3
  • 162
    • 80053559849 scopus 로고    scopus 로고
    • Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells
    • Pirola, L., Balcerczyk, A., Tothill, R.W., Haviv, I., Kaspi, A., Lunke, S., et al. Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells. Genome Res 21:10 (2011), 1601–1615.
    • (2011) Genome Res , vol.21 , Issue.10 , pp. 1601-1615
    • Pirola, L.1    Balcerczyk, A.2    Tothill, R.W.3    Haviv, I.4    Kaspi, A.5    Lunke, S.6
  • 163
    • 43549108142 scopus 로고    scopus 로고
    • Glucolipotoxicity: fuel excess and β-cell dysfunction
    • Poitout, V., Robertson, R.P., Glucolipotoxicity: fuel excess and β-cell dysfunction. Endocr. Rev 29:3 (2008), 351–366.
    • (2008) Endocr. Rev , vol.29 , Issue.3 , pp. 351-366
    • Poitout, V.1    Robertson, R.P.2
  • 164
    • 73649125812 scopus 로고    scopus 로고
    • Transcription factors Krüppel-like factor 6 and peroxisome proliferator-activated receptor-γ mediate high glucose-induced thioredoxin-interacting protein
    • Qi, W., Chen, X., Holian, J., Tan, C.Y.R., Kelly, D.J., Pollock, C.A., Transcription factors Krüppel-like factor 6 and peroxisome proliferator-activated receptor-γ mediate high glucose-induced thioredoxin-interacting protein. Am. J. Pathol 175:5 (2009), 1858–1867.
    • (2009) Am. J. Pathol , vol.175 , Issue.5 , pp. 1858-1867
    • Qi, W.1    Chen, X.2    Holian, J.3    Tan, C.Y.R.4    Kelly, D.J.5    Pollock, C.A.6
  • 165
    • 84905654622 scopus 로고    scopus 로고
    • Vascular histone deacetylation by pharmacological HDAC inhibition
    • Rafehi, H., Balcerczyk, A., Lunke, S., Kaspi, A., Ziemann, M., Kn, H., et al. Vascular histone deacetylation by pharmacological HDAC inhibition. Genome Res 24:8 (2014), 1271–1284.
    • (2014) Genome Res , vol.24 , Issue.8 , pp. 1271-1284
    • Rafehi, H.1    Balcerczyk, A.2    Lunke, S.3    Kaspi, A.4    Ziemann, M.5    Kn, H.6
  • 166
    • 84867909223 scopus 로고    scopus 로고
    • Histone deacetylase 5 regulates glucose uptake and insulin action in muscle cells
    • Raichur, S., Teh, S.H., Ohwaki, K., Gaur, V., Long, Y.C., Hargreaves, M., et al. Histone deacetylase 5 regulates glucose uptake and insulin action in muscle cells. J. Mol. Endocrinol 49:3 (2012), 203–211.
    • (2012) J. Mol. Endocrinol , vol.49 , Issue.3 , pp. 203-211
    • Raichur, S.1    Teh, S.H.2    Ohwaki, K.3    Gaur, V.4    Long, Y.C.5    Hargreaves, M.6
  • 167
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-α and SIRT1
    • Rodgers, J.T., Lerin, C., Haas, W., Gygi, S.P., Spiegelman, B.M., Puigserver, P., Nutrient control of glucose homeostasis through a complex of PGC-α and SIRT1. Nature 434:7029 (2005), 113–118.
    • (2005) Nature , vol.434 , Issue.7029 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 168
    • 84867183192 scopus 로고    scopus 로고
    • Histone phosphorylation: a chromatin modification involved in diverse nuclear events
    • Rossetto, D., Avvakumov, N., Cote, J., Histone phosphorylation: a chromatin modification involved in diverse nuclear events. Epigenetics 7:10 (2012), 1098–1108.
    • (2012) Epigenetics , vol.7 , Issue.10 , pp. 1098-1108
    • Rossetto, D.1    Avvakumov, N.2    Cote, J.3
  • 169
    • 44749089106 scopus 로고    scopus 로고
    • Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle
    • Rönn, T., Poulsen, P., Hansson, O., Holmkvist, J., Almgren, P., Nilsson, P., et al. Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle. Diabetologia 51:7 (2008), 1159–1168.
    • (2008) Diabetologia , vol.51 , Issue.7 , pp. 1159-1168
    • Rönn, T.1    Poulsen, P.2    Hansson, O.3    Holmkvist, J.4    Almgren, P.5    Nilsson, P.6
  • 170
    • 84879678934 scopus 로고    scopus 로고
    • A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue
    • e1003572
    • Rönn, T., Volkov, P., Davegårdh, C., Dayeh, T., Hall, E., Olsson, A.H., et al. A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue. PLoS Genet, 9(6), 2013 e1003572.
    • (2013) PLoS Genet , vol.9 , Issue.6
    • Rönn, T.1    Volkov, P.2    Davegårdh, C.3    Dayeh, T.4    Hall, E.5    Olsson, A.H.6
  • 171
    • 78650447665 scopus 로고    scopus 로고
    • β-N-acetylglucosamine (O-GlcNAc) is part of the histone code
    • Sakabe, K., Wang, Z., Hart, G.W., β-N-acetylglucosamine (O-GlcNAc) is part of the histone code. Proc. Natl. Acad. Sci. U.S.A. 107:46 (2010), 19915–19920.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , Issue.46 , pp. 19915-19920
    • Sakabe, K.1    Wang, Z.2    Hart, G.W.3
  • 172
    • 84954424294 scopus 로고    scopus 로고
    • Inhibition of SET domain–containing lysine methyltransferase 7/9 ameliorates renal fibrosis
    • Sasaki, K., Doi, S., Nakashima, A., Irifuku, T., Yamada, K., Kokoroishi, K., et al. Inhibition of SET domain–containing lysine methyltransferase 7/9 ameliorates renal fibrosis. J. Am. Soc. Nephrol 27:1 (2016), 203–2015.
    • (2016) J. Am. Soc. Nephrol , vol.27 , Issue.1 , pp. 203-2015
    • Sasaki, K.1    Doi, S.2    Nakashima, A.3    Irifuku, T.4    Yamada, K.5    Kokoroishi, K.6
  • 173
    • 0029076281 scopus 로고
    • Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-b as a key mediator
    • Sharma, K., Ziyadeh, F.N., Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-b as a key mediator. Diabetes 44 (1995), 1139–1146.
    • (1995) Diabetes , vol.44 , pp. 1139-1146
    • Sharma, K.1    Ziyadeh, F.N.2
  • 174
    • 84905647959 scopus 로고    scopus 로고
    • Epigenetic histone methylation regulates transforming growth factor β-1 expression following bile duct ligation in rats
    • Sheen-Chen, S.-M., Lin, C.-R., Chen, K.-H., Yang, C.-H., Lee, C.-T., Huang, H.-W., et al. Epigenetic histone methylation regulates transforming growth factor β-1 expression following bile duct ligation in rats. J. Gastroenterol 49:8 (2014), 1285–1297.
    • (2014) J. Gastroenterol , vol.49 , Issue.8 , pp. 1285-1297
    • Sheen-Chen, S.-M.1    Lin, C.-R.2    Chen, K.-H.3    Yang, C.-H.4    Lee, C.-T.5    Huang, H.-W.6
  • 175
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • Shi, Y., Lan, F., Matson, C., Mulligan, P., Whetstine, J.R., Cole, P.A., et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119:7 (2004), 941–953.
    • (2004) Cell , vol.119 , Issue.7 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6
  • 176
    • 84872166360 scopus 로고    scopus 로고
    • Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor
    • Shimazu, T., Hirschey, M.D., Newman, J., He, W., Shirakawa, K., Le Moan, N., et al. Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science 339:6116 (2013), 211–214.
    • (2013) Science , vol.339 , Issue.6116 , pp. 211-214
    • Shimazu, T.1    Hirschey, M.D.2    Newman, J.3    He, W.4    Shirakawa, K.5    Le Moan, N.6
  • 177
    • 84872160110 scopus 로고    scopus 로고
    • Influence of threonine metabolism on S-adenosylmethionine and histone methylation
    • Shyh-Chang, N., Locasale, J.W., Lyssiotis, C.A., Zheng, Y., Teo, R.Y., Ratanasirintrawoot, S., et al. Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science 339:6116 (2013), 222–226.
    • (2013) Science , vol.339 , Issue.6116 , pp. 222-226
    • Shyh-Chang, N.1    Locasale, J.W.2    Lyssiotis, C.A.3    Zheng, Y.4    Teo, R.Y.5    Ratanasirintrawoot, S.6
  • 178
    • 1842591163 scopus 로고    scopus 로고
    • Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300
    • Simone, C., Stiegler, P., Forcales, S.-V., Bagella, L., De Luca, A., Sartorelli, V., et al. Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300. Oncogene 23:12 (2004), 2177–2187.
    • (2004) Oncogene , vol.23 , Issue.12 , pp. 2177-2187
    • Simone, C.1    Stiegler, P.2    Forcales, S.-V.3    Bagella, L.4    De Luca, A.5    Sartorelli, V.6
  • 179
    • 0030768745 scopus 로고    scopus 로고
    • Steroid receptor coactivator-1 is a histone acetyltransferase
    • Spencer, T.E., Jenster, G., Burcin, M.M., Allis, C.D., Zhou, J., Mizzen, C.A., et al. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature 389:6647 (1997), 194–198.
    • (1997) Nature , vol.389 , Issue.6647 , pp. 194-198
    • Spencer, T.E.1    Jenster, G.2    Burcin, M.M.3    Allis, C.D.4    Zhou, J.5    Mizzen, C.A.6
  • 180
    • 79957851295 scopus 로고    scopus 로고
    • Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats
    • Strakovsky, R.S., Zhang, X., Zhou, D., Pan, Y.-X., Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats. J. Physiol 589:11 (2011), 2707–2717.
    • (2011) J. Physiol , vol.589 , Issue.11 , pp. 2707-2717
    • Strakovsky, R.S.1    Zhang, X.2    Zhou, D.3    Pan, Y.-X.4
  • 181
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
    • Stratton, I.M., Adler, A.I., Neil, A.W., Matthews, D.R., Manley, S.E., Cull, C.A., et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 321 (2000), 405–412.
    • (2000) BMJ , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, A.W.3    Matthews, D.R.4    Manley, S.E.5    Cull, C.A.6
  • 182
    • 84919841585 scopus 로고    scopus 로고
    • PCAF improves glucose homeostasis by suppressing the gluconeogenic activity of PGC-1α
    • Sun, C., Wang, M., Liu, X., Luo, L., Li, K., Zhang, S., et al. PCAF improves glucose homeostasis by suppressing the gluconeogenic activity of PGC-1α. Cell Rep 9:6 (2014), 2250–2262.
    • (2014) Cell Rep , vol.9 , Issue.6 , pp. 2250-2262
    • Sun, C.1    Wang, M.2    Liu, X.3    Luo, L.4    Li, K.5    Zhang, S.6
  • 184
    • 84870316797 scopus 로고    scopus 로고
    • A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates
    • Suter, M.A., Chen, A., Burdine, M.S., Choudhury, M., Harris, R.A., Lane, R.H., et al. A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J. 26:12 (2012), 5106–5114.
    • (2012) FASEB J. , vol.26 , Issue.12 , pp. 5106-5114
    • Suter, M.A.1    Chen, A.2    Burdine, M.S.3    Choudhury, M.4    Harris, R.A.5    Lane, R.H.6
  • 185
    • 84899756754 scopus 로고    scopus 로고
    • In utero exposure to a maternal high-fat diet alters the epigenetic histone code in a murine model
    • e461-463.e411
    • Suter, M.A., Ma, J., Vuguin, P.M., Hartil, K., Fiallo, A., Harris, R.A., et al. In utero exposure to a maternal high-fat diet alters the epigenetic histone code in a murine model. Am. J. Obstet. Gynecol, 210(5), 2014, 463 e461-463.e411.
    • (2014) Am. J. Obstet. Gynecol , vol.210 , Issue.5 , pp. 463
    • Suter, M.A.1    Ma, J.2    Vuguin, P.M.3    Hartil, K.4    Fiallo, A.5    Harris, R.A.6
  • 186
    • 85015261546 scopus 로고    scopus 로고
    • SIRT7 and hepatic lipid metabolism
    • Tang, B.L., SIRT7 and hepatic lipid metabolism. Front. Cell Dev. Biol, 3, 2015, 1.
    • (2015) Front. Cell Dev. Biol , vol.3 , pp. 1
    • Tang, B.L.1
  • 187
    • 84874688338 scopus 로고    scopus 로고
    • Histone deacetylases as targets for treatment of multiple diseases
    • Tang, J., Yan, H., Zhuang, S., Histone deacetylases as targets for treatment of multiple diseases. Clin. Sci 124:11 (2013), 651–662.
    • (2013) Clin. Sci , vol.124 , Issue.11 , pp. 651-662
    • Tang, J.1    Yan, H.2    Zhuang, S.3
  • 188
    • 84907638046 scopus 로고    scopus 로고
    • Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis
    • Tannour-Louet, M., York, B., Tang, K., Stashi, E., Bouguerra, H., Zhou, S., et al. Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis. Mol. Endocrinol 28:10 (2014), 1707–1718.
    • (2014) Mol. Endocrinol , vol.28 , Issue.10 , pp. 1707-1718
    • Tannour-Louet, M.1    York, B.2    Tang, K.3    Stashi, E.4    Bouguerra, H.5    Zhou, S.6
  • 189
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • Tateishi, K., Okada, Y., Kallin, E.M., Zhang, Y., Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 458:7239 (2009), 757–761.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 757-761
    • Tateishi, K.1    Okada, Y.2    Kallin, E.M.3    Zhang, Y.4
  • 190
    • 0141672132 scopus 로고    scopus 로고
    • Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism
    • Teixeira, L., Rabouille, C., Rørth, P., Ephrussi, A., Vanzo, N.F., Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism. Mech. Dev 120:9 (2003), 1071–1081.
    • (2003) Mech. Dev , vol.120 , Issue.9 , pp. 1071-1081
    • Teixeira, L.1    Rabouille, C.2    Rørth, P.3    Ephrussi, A.4    Vanzo, N.F.5
  • 191
    • 84875269038 scopus 로고    scopus 로고
    • Quantification of excess risk for diabetes for those born in times of hunger, in an entire population of a nation, across a century
    • Thurner, S., Klimek, P., Szell, M., Duftschmid, G., Endel, G., Kautzky-Willer, A., et al. Quantification of excess risk for diabetes for those born in times of hunger, in an entire population of a nation, across a century. Proc. Natl. Acad. Sci. U.S.A. 110:12 (2013), 4703–4707.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , Issue.12 , pp. 4703-4707
    • Thurner, S.1    Klimek, P.2    Szell, M.3    Duftschmid, G.4    Endel, G.5    Kautzky-Willer, A.6
  • 192
    • 84923326770 scopus 로고    scopus 로고
    • DNA methylation signatures link prenatal famine exposure to growth and metabolism
    • Tobi, E.W., Goeman, J.J., Monajemi, R., Gu, H., Putter, H., Zhang, Y., et al. DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nat. Commun, 5, 2014, 5592.
    • (2014) Nat. Commun , vol.5 , pp. 5592
    • Tobi, E.W.1    Goeman, J.J.2    Monajemi, R.3    Gu, H.4    Putter, H.5    Zhang, Y.6
  • 195
    • 84976499944 scopus 로고    scopus 로고
    • DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma
    • Udali, S., Guarini, P., Ruzzenente, A., Ferrarini, A., Guglielmi, A., Lotto, V., et al. DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma. Clin. Epigenetics 7:1 (2015), 1–13.
    • (2015) Clin. Epigenetics , vol.7 , Issue.1 , pp. 1-13
    • Udali, S.1    Guarini, P.2    Ruzzenente, A.3    Ferrarini, A.4    Guglielmi, A.5    Lotto, V.6
  • 196
  • 197
    • 84978061514 scopus 로고    scopus 로고
    • Transgenerational epigenetic inheritance in mammals: how good is the evidence?
    • Van Otterdijk, S.D., Michels, K.B., Transgenerational epigenetic inheritance in mammals: how good is the evidence?. FASEB J. 30:7 (2016), 2457–2465.
    • (2016) FASEB J. , vol.30 , Issue.7 , pp. 2457-2465
    • Van Otterdijk, S.D.1    Michels, K.B.2
  • 198
    • 36248954501 scopus 로고    scopus 로고
    • SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
    • Vaquero, A., Scher, M., Erdjument-Bromage, H., Tempst, P., Serrano, L., Reinberg, D., SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature 450:7168 (2007), 440–444.
    • (2007) Nature , vol.450 , Issue.7168 , pp. 440-444
    • Vaquero, A.1    Scher, M.2    Erdjument-Bromage, H.3    Tempst, P.4    Serrano, L.5    Reinberg, D.6
  • 199
    • 84890320109 scopus 로고    scopus 로고
    • EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD
    • Vella, S., Gnani, D., Crudele, A., Ceccarelli, S., De Stefanis, C., Gaspari, S., et al. EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD. Int. J. Mol. Sci, 14(12), 2013, 24154.
    • (2013) Int. J. Mol. Sci , vol.14 , Issue.12 , pp. 24154
    • Vella, S.1    Gnani, D.2    Crudele, A.3    Ceccarelli, S.4    De Stefanis, C.5    Gaspari, S.6
  • 200
    • 48249127225 scopus 로고    scopus 로고
    • Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes
    • Villeneuve, L.M., Reddy, M.A., Lanting, L.L., Wang, M., Meng, L., Natarajan, R., Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proc. Natl. Acad. Sci. U.S.A. 105:26 (2008), 9047–9052.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , Issue.26 , pp. 9047-9052
    • Villeneuve, L.M.1    Reddy, M.A.2    Lanting, L.L.3    Wang, M.4    Meng, L.5    Natarajan, R.6
  • 201
    • 84891953688 scopus 로고    scopus 로고
    • JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α–mediated glucose metabolism
    • Wang, H.-J., Hsieh, Y.-J., Cheng, W.-C., Lin, C.-P., Lin, Y.-S., Yang, S.-F., et al. JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α–mediated glucose metabolism. Proc. Natl. Acad. Sci. U.S.A. 111:1 (2014), 279–284.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , Issue.1 , pp. 279-284
    • Wang, H.-J.1    Hsieh, Y.-J.2    Cheng, W.-C.3    Lin, C.-P.4    Lin, Y.-S.5    Yang, S.-F.6
  • 202
    • 84872867103 scopus 로고    scopus 로고
    • Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis
    • Wang, L., Xu, S., Lee, J.-E., Baldridge, A., Grullon, S., Peng, W., et al. Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis. EMBO J. 32:1 (2013), 45–59.
    • (2013) EMBO J. , vol.32 , Issue.1 , pp. 45-59
    • Wang, L.1    Xu, S.2    Lee, J.-E.3    Baldridge, A.4    Grullon, S.5    Peng, W.6
  • 203
    • 84860879649 scopus 로고    scopus 로고
    • CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells
    • Wang, S.C., Dowhan, D.H., Eriksson, N.A., Muscat, G.E., CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells. Biochem. J. 444:2 (2012), 323–331.
    • (2012) Biochem. J. , vol.444 , Issue.2 , pp. 323-331
    • Wang, S.C.1    Dowhan, D.H.2    Eriksson, N.A.3    Muscat, G.E.4
  • 204
    • 69449102464 scopus 로고    scopus 로고
    • Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
    • Wang, Z., Zang, C., Cui, K., Schones, D.E., Barski, A., Peng, W., et al. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138:5 (2009), 1019–1031.
    • (2009) Cell , vol.138 , Issue.5 , pp. 1019-1031
    • Wang, Z.1    Zang, C.2    Cui, K.3    Schones, D.E.4    Barski, A.5    Peng, W.6
  • 205
    • 0035986095 scopus 로고    scopus 로고
    • Dynamics of histone acetylation in vivo. A function for acetylation turnover?
    • Waterborg, J., Dynamics of histone acetylation in vivo. A function for acetylation turnover?. Biochem. Cell Biol 80:3 (2002), 363–378.
    • (2002) Biochem. Cell Biol , vol.80 , Issue.3 , pp. 363-378
    • Waterborg, J.1
  • 206
    • 84929459565 scopus 로고    scopus 로고
    • Enriched environment-induced maternal weight loss reprograms metabolic gene expression in mouse offspring
    • Wei, Y., Yang, C.-R., Wei, Y.-P., Ge, Z.-J., Zhao, Z.-A., Zhang, B., et al. Enriched environment-induced maternal weight loss reprograms metabolic gene expression in mouse offspring. J. Biol. Chem 290:8 (2015), 4604–4619.
    • (2015) J. Biol. Chem , vol.290 , Issue.8 , pp. 4604-4619
    • Wei, Y.1    Yang, C.-R.2    Wei, Y.-P.3    Ge, Z.-J.4    Zhao, Z.-A.5    Zhang, B.6
  • 208
    • 84892942381 scopus 로고    scopus 로고
    • New and emerging HDAC inhibitors for cancer treatment
    • West, A.C., Johnstone, R.W., New and emerging HDAC inhibitors for cancer treatment. J. Clin. Invest 124:1 (2014), 30–39.
    • (2014) J. Clin. Invest , vol.124 , Issue.1 , pp. 30-39
    • West, A.C.1    Johnstone, R.W.2
  • 209
    • 84856541549 scopus 로고    scopus 로고
    • Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis
    • Winkler, R., Benz, V., Clemenz, M., Bloch, M., Foryst-Ludwig, A., Wardat, S., et al. Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis. Diabetes 61:2 (2012), 513–523.
    • (2012) Diabetes , vol.61 , Issue.2 , pp. 513-523
    • Winkler, R.1    Benz, V.2    Clemenz, M.3    Bloch, M.4    Foryst-Ludwig, A.5    Wardat, S.6
  • 210
    • 63449103705 scopus 로고    scopus 로고
    • Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
    • Xia, X., Lemieux, M.E., Li, W., Carroll, J.S., Brown, M., Liu, X.S., et al. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc. Natl. Acad. Sci. U.S.A. 106:11 (2009), 4260–4265.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , Issue.11 , pp. 4260-4265
    • Xia, X.1    Lemieux, M.E.2    Li, W.3    Carroll, J.S.4    Brown, M.5    Liu, X.S.6
  • 211
    • 84934780244 scopus 로고    scopus 로고
    • Myocardin-related transcription factor A epigenetically regulates renal fibrosis in diabetic nephropathy
    • Xu, H., Wu, X., Qin, H., Tian, W., Chen, J., Sun, L., et al. Myocardin-related transcription factor A epigenetically regulates renal fibrosis in diabetic nephropathy. J. Am. Soc. Nephrol 26:7 (2015), 1648–1660.
    • (2015) J. Am. Soc. Nephrol , vol.26 , Issue.7 , pp. 1648-1660
    • Xu, H.1    Wu, X.2    Qin, H.3    Tian, W.4    Chen, J.5    Sun, L.6
  • 212
    • 78651463452 scopus 로고    scopus 로고
    • Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
    • Xu, W., Yang, H., Liu, Y., Yang, Y., Wang, P., Kim, S.-H., et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell 19:1 (2011), 17–30.
    • (2011) Cancer Cell , vol.19 , Issue.1 , pp. 17-30
    • Xu, W.1    Yang, H.2    Liu, Y.3    Yang, Y.4    Wang, P.5    Kim, S.-H.6
  • 213
    • 34548627517 scopus 로고    scopus 로고
    • Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
    • Yang, H., Yang, T., Baur, J.A., Perez, E., Matsui, T., Carmona, J.J., et al. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell 130:6 (2007), 1095–1107.
    • (2007) Cell , vol.130 , Issue.6 , pp. 1095-1107
    • Yang, H.1    Yang, T.2    Baur, J.A.3    Perez, E.4    Matsui, T.5    Carmona, J.J.6
  • 214
    • 0037067659 scopus 로고    scopus 로고
    • Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression
    • Yang, X., Zhang, F., Kudlow, J., Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. Cell 110 (2002), 69–80.
    • (2002) Cell , vol.110 , pp. 69-80
    • Yang, X.1    Zhang, F.2    Kudlow, J.3
  • 215
    • 84880344660 scopus 로고    scopus 로고
    • Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals
    • Yin, R., Mao, S.-Q., Zhao, B., Chong, Z., Yang, Y., Zhao, C., et al. Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J. Am. Chem. Soc 135:28 (2013), 10396–10403.
    • (2013) J. Am. Chem. Soc , vol.135 , Issue.28 , pp. 10396-10403
    • Yin, R.1    Mao, S.-Q.2    Zhao, B.3    Chong, Z.4    Yang, Y.5    Zhao, C.6
  • 216
    • 0033036593 scopus 로고    scopus 로고
    • DNA demethylation during the differentiation of 3T3-L1 cells affects the expression of the mouse GLUT4 gene
    • Yokomori, N., Tawata, M., Onaya, T., DNA demethylation during the differentiation of 3T3-L1 cells affects the expression of the mouse GLUT4 gene. Diabetes, 48(4), 1999, 685.
    • (1999) Diabetes , vol.48 , Issue.4 , pp. 685
    • Yokomori, N.1    Tawata, M.2    Onaya, T.3
  • 217
    • 84874643841 scopus 로고    scopus 로고
    • Involvement of p300/CBP and epigenetic histone acetylation in TGF-beta1-mediated gene transcription in mesangial cells
    • Yuan, H., Reddy, M.A., Sun, G., Lanting, L., Wang, M., Kato, M., et al. Involvement of p300/CBP and epigenetic histone acetylation in TGF-beta1-mediated gene transcription in mesangial cells. Am. J. Physiol. Renal Physiol 304:5 (2013), F601–F613.
    • (2013) Am. J. Physiol. Renal Physiol , vol.304 , Issue.5 , pp. F601-F613
    • Yuan, H.1    Reddy, M.A.2    Sun, G.3    Lanting, L.4    Wang, M.5    Kato, M.6
  • 218
    • 84959237489 scopus 로고    scopus 로고
    • Epigenetic histone modifications involved in pro-fibrotic gene regulation by 12/15-lipoxygenase and its oxidized lipid products in diabetic nephropathy
    • Yuan, H., Reddy, M., Deshpande, S., Jia, Y., Park, J.T., Lanting, L., et al. Epigenetic histone modifications involved in pro-fibrotic gene regulation by 12/15-lipoxygenase and its oxidized lipid products in diabetic nephropathy. Antioxid. Redox Signal 24:7 (2016), 361–375.
    • (2016) Antioxid. Redox Signal , vol.24 , Issue.7 , pp. 361-375
    • Yuan, H.1    Reddy, M.2    Deshpande, S.3    Jia, Y.4    Park, J.T.5    Lanting, L.6
  • 219
    • 79955384015 scopus 로고    scopus 로고
    • Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation
    • Zhang, J., Henagan, T.M., Gao, Z., Ye, J., Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation. Endocrinology 152:5 (2011), 1829–1838.
    • (2011) Endocrinology , vol.152 , Issue.5 , pp. 1829-1838
    • Zhang, J.1    Henagan, T.M.2    Gao, Z.3    Ye, J.4
  • 220
    • 84901364916 scopus 로고    scopus 로고
    • Suv39h1 mediates AP-2α-dependent inhibition of C/EBPα expression during adipogenesis
    • Zhang, Z.-C., Liu, Y., Li, S.-F., Guo, L., Zhao, Y., Qian, S.-W., et al. Suv39h1 mediates AP-2α-dependent inhibition of C/EBPα expression during adipogenesis. Mol. Cell. Biol 34:12 (2014), 2330–2338.
    • (2014) Mol. Cell. Biol , vol.34 , Issue.12 , pp. 2330-2338
    • Zhang, Z.-C.1    Liu, Y.2    Li, S.-F.3    Guo, L.4    Zhao, Y.5    Qian, S.-W.6
  • 221
    • 84953327405 scopus 로고    scopus 로고
    • KDM4C and ATF4 cooperate in transcriptional control of amino acid metabolism
    • Zhao, E., Ding, J., Xia, Y., Liu, M., Ye, B., Choi, J.-H., et al. KDM4C and ATF4 cooperate in transcriptional control of amino acid metabolism. Cell Rep 14:3 (2016), 506–519.
    • (2016) Cell Rep , vol.14 , Issue.3 , pp. 506-519
    • Zhao, E.1    Ding, J.2    Xia, Y.3    Liu, M.4    Ye, B.5    Choi, J.-H.6
  • 222
    • 80052580047 scopus 로고    scopus 로고
    • Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction
    • Zhou, S., Chen, H.-Z., Wan, Y.-Z., Zhang, Q.-J., Wei, Y.-S., Huang, S., et al. Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. Circ. Res 109:6 (2011), 639–648.
    • (2011) Circ. Res , vol.109 , Issue.6 , pp. 639-648
    • Zhou, S.1    Chen, H.-Z.2    Wan, Y.-Z.3    Zhang, Q.-J.4    Wei, Y.-S.5    Huang, S.6


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