-
1
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51:2944-2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
2
-
-
0032768885
-
Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle
-
Huang X, Eriksson KF, Vaag A et al (1999) Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle. Diabetes 48:1508-1514
-
(1999)
Diabetes
, vol.48
, pp. 1508-1514
-
-
Huang, X.1
Eriksson, K.F.2
Vaag, A.3
-
3
-
-
0038054341
-
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF et al (2003) PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267-273
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
-
4
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S et al (2003) Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 100:8466-8471
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
-
5
-
-
0036266251
-
Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment
-
Sreekumar R, Halvatsiotis P, Schimke JC, Nair KS (2002) Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment. Diabetes 51:1913-1920
-
(2002)
Diabetes
, vol.51
, pp. 1913-1920
-
-
Sreekumar, R.1
Halvatsiotis, P.2
Schimke, J.C.3
Nair, K.S.4
-
6
-
-
0030717483
-
Genomic sequence and organization of the human gene for cytochrome c oxidase subunit (COX7A1) VIIa-M
-
Wolz W, Kress W, Mueller CR (1997) Genomic sequence and organization of the human gene for cytochrome c oxidase subunit (COX7A1) VIIa-M. Genomics 45:438-442
-
(1997)
Genomics
, vol.45
, pp. 438-442
-
-
Wolz, W.1
Kress, W.2
Mueller, C.R.3
-
7
-
-
33645316059
-
Tissue specificity of methylation of cytosines in regulatory regions of four genes located in the locus FXYD5-COX7A1 of human chromosome 19: Correlation with their expression level
-
Chalaya TV, Akopov SB, Nikolaev LG, Sverdlov ED (2006) Tissue specificity of methylation of cytosines in regulatory regions of four genes located in the locus FXYD5-COX7A1 of human chromosome 19: correlation with their expression level. Biochemistry 71:294-299
-
(2006)
Biochemistry
, vol.71
, pp. 294-299
-
-
Chalaya, T.V.1
Akopov, S.B.2
Nikolaev, L.G.3
Sverdlov, E.D.4
-
8
-
-
0026726965
-
Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase
-
Arnaudo E, Hirano M, Seelan RS et al (1992) Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase. Gene 119:299-305
-
(1992)
Gene
, vol.119
, pp. 299-305
-
-
Arnaudo, E.1
Hirano, M.2
Seelan, R.S.3
-
9
-
-
34548032087
-
Genome-wide association studies provide new insights into type 2 diabetes aetiology
-
Frayling TM (2007) Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat Rev 8:657-662
-
(2007)
Nat Rev
, vol.8
, pp. 657-662
-
-
Frayling, T.M.1
-
10
-
-
85047691371
-
Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins
-
Ling C, Poulsen P, Carlsson E et al (2004) Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins. J Clin Invest 114:1518-1526
-
(2004)
J Clin Invest
, vol.114
, pp. 1518-1526
-
-
Ling, C.1
Poulsen, P.2
Carlsson, E.3
-
11
-
-
34447120855
-
Impact of the peroxisome proliferator activated receptor-gamma coactivator-1β (PGC-1β) Ala203Pro polymorphism on in vivo metabolism, PGC-1β expression and fibre type composition in human skeletal muscle
-
Ling C, Wegner L, Andersen G et al (2007) Impact of the peroxisome proliferator activated receptor-gamma coactivator-1β (PGC-1β) Ala203Pro polymorphism on in vivo metabolism, PGC-1β expression and fibre type composition in human skeletal muscle. Diabetologia 50:1615-1620
-
(2007)
Diabetologia
, vol.50
, pp. 1615-1620
-
-
Ling, C.1
Wegner, L.2
Andersen, G.3
-
12
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI (2004) Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350:664-671
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
13
-
-
36049002392
-
Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle
-
Ling C, Poulsen P, Simonsson S et al (2007) Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle. J Clin Invest 117:3427-3435
-
(2007)
J Clin Invest
, vol.117
, pp. 3427-3435
-
-
Ling, C.1
Poulsen, P.2
Simonsson, S.3
-
14
-
-
0037096760
-
Type 2 diabetes is associated with a common mitochondrial variant: Evidence from a population-based case-control study
-
Poulton J, Luan J, Macaulay V, Hennings S, Mitchell J, Wareham NJ (2002) Type 2 diabetes is associated with a common mitochondrial variant: evidence from a population-based case-control study. Hum Mol Genet 11:1581-1583
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1581-1583
-
-
Poulton, J.1
Luan, J.2
MacAulay, V.3
Hennings, S.4
Mitchell, J.5
Wareham, N.J.6
-
15
-
-
0026906885
-
Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness
-
van den Ouweland JM, Lemkes HH, Ruitenbeek W et al (1992) Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet 1:368-371
-
(1992)
Nat Genet
, vol.1
, pp. 368-371
-
-
Van Den Ouweland, J.M.1
Lemkes, H.H.2
Ruitenbeek, W.3
-
16
-
-
8444228909
-
A cluster of metabolic defects caused by mutation in a mitochondrial tRNA
-
Wilson FH, Hariri A, Farhi A et al (2004) A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science 306:1190-1194
-
(2004)
Science
, vol.306
, pp. 1190-1194
-
-
Wilson, F.H.1
Hariri, A.2
Farhi, A.3
-
17
-
-
0036460038
-
Age-dependent impact of zygosity and birth weight on insulin secretion and insulin action in twins
-
Poulsen P, Levin K, Beck-Nielsen H, Vaag A (2002) Age-dependent impact of zygosity and birth weight on insulin secretion and insulin action in twins. Diabetologia 45:1649-1657
-
(2002)
Diabetologia
, vol.45
, pp. 1649-1657
-
-
Poulsen, P.1
Levin, K.2
Beck-Nielsen, H.3
Vaag, A.4
-
18
-
-
33748308771
-
The intrauterine environment as reflected by birth size and twin and zygosity status influences insulin action and intracellular glucose metabolism in an age- or time-dependent manner
-
Poulsen P, Vaag A (2006) The intrauterine environment as reflected by birth size and twin and zygosity status influences insulin action and intracellular glucose metabolism in an age- or time-dependent manner. Diabetes 55:1819-1825
-
(2006)
Diabetes
, vol.55
, pp. 1819-1825
-
-
Poulsen, P.1
Vaag, A.2
-
19
-
-
0003014882
-
Metabolic consequences of a family history of NIDDM (the Botnia Study): Evidence for sex-specific parental effects
-
Groop L, Forsblom C, Lehtovirta M et al (1996) Metabolic consequences of a family history of NIDDM (the Botnia Study): evidence for sex-specific parental effects. Diabetes 45:1585-1593
-
(1996)
Diabetes
, vol.45
, pp. 1585-1593
-
-
Groop, L.1
Forsblom, C.2
Lehtovirta, M.3
-
20
-
-
0035758580
-
Classifying diabetes according to the new WHO clinical stages
-
Lindholm E, Agardh E, Tuomi T, Groop L, Agardh CD (2001) Classifying diabetes according to the new WHO clinical stages. Eur J Epidemiol 17:983-989
-
(2001)
Eur J Epidemiol
, vol.17
, pp. 983-989
-
-
Lindholm, E.1
Agardh, E.2
Tuomi, T.3
Groop, L.4
Agardh, C.D.5
-
21
-
-
9644272567
-
The association between total energy intake and early mortality: Data from the Malmo Diet and Cancer Study
-
Leosdottir M, Nilsson P, Nilsson JA, Mansson H, Berglund G (2004) The association between total energy intake and early mortality: data from the Malmo Diet and Cancer Study. J Intern Med 256:499-509
-
(2004)
J Intern Med
, vol.256
, pp. 499-509
-
-
Leosdottir, M.1
Nilsson, P.2
Nilsson, J.A.3
Mansson, H.4
Berglund, G.5
-
22
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539-553
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
23
-
-
12144273136
-
Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins
-
Poulsen P, Levin K, Petersen I, Christensen K, Beck-Nielsen H, Vaag A (2005) Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins. Diabetes 54:275-283
-
(2005)
Diabetes
, vol.54
, pp. 275-283
-
-
Poulsen, P.1
Levin, K.2
Petersen, I.3
Christensen, K.4
Beck-Nielsen, H.5
Vaag, A.6
-
24
-
-
0021396983
-
Europium as a label in time-resolved immunofluorometric assays
-
Hemmila I, Dakubu S, Mukkala VM, Siitari H, Lovgren T (1984) Europium as a label in time-resolved immunofluorometric assays. Anal Biochem 137:335-343
-
(1984)
Anal Biochem
, vol.137
, pp. 335-343
-
-
Hemmila, I.1
Dakubu, S.2
Mukkala, V.M.3
Siitari, H.4
Lovgren, T.5
-
25
-
-
0025089269
-
On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion
-
Hother-Nielsen O, Beck-Nielsen H (1990) On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion. Diabetologia 33:603-610
-
(1990)
Diabetologia
, vol.33
, pp. 603-610
-
-
Hother-Nielsen, O.1
Beck-Nielsen, H.2
-
26
-
-
0036856355
-
MethPrimer: Designing primers for methylation PCRs
-
Li LC, Dahiya R (2002) MethPrimer: designing primers for methylation PCRs. Bioinformatics (Oxford, England) 18:1427-1431
-
(2002)
Bioinformatics (Oxford, England)
, vol.18
, pp. 1427-1431
-
-
Li, L.C.1
Dahiya, R.2
-
27
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M (1987) CpG islands in vertebrate genomes. J Mol Biol 196:261-282
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
28
-
-
27744577751
-
BiQ analyzer: Visualization and quality control for DNA methylation data from bisulfite sequencing
-
Bock C, Reither S, Mikeska T, Paulsen M, Walter J, Lengauer T (2005) BiQ analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics (Oxford, England) 21:4067-4068
-
(2005)
Bioinformatics (Oxford, England)
, vol.21
, pp. 4067-4068
-
-
Bock, C.1
Reither, S.2
Mikeska, T.3
Paulsen, M.4
Walter, J.5
Lengauer, T.6
-
29
-
-
4544293301
-
Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates
-
Lewin J, Schmitt AO, Adorjan P, Hildmann T, Piepenbrock C (2004) Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates. Bioinformatics 20:3005-3012
-
(2004)
Bioinformatics
, vol.20
, pp. 3005-3012
-
-
Lewin, J.1
Schmitt, A.O.2
Adorjan, P.3
Hildmann, T.4
Piepenbrock, C.5
-
31
-
-
79959503826
-
The International HapMap Project
-
The International HapMap Consortium
-
The International HapMap Consortium (2003) The International HapMap Project. Nature 426:789-796
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
32
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (Oxford, England) 21:263-265
-
(2005)
Bioinformatics (Oxford, England)
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
34
-
-
0022673130
-
Longitudinal data analysis for discrete and continuous outcomes
-
Zeger SL, Liang KY (1986) Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42:121-130
-
(1986)
Biometrics
, vol.42
, pp. 121-130
-
-
Zeger, S.L.1
Liang, K.Y.2
-
35
-
-
32544445975
-
Genetic and nongenetic determinants of skeletal muscle glucose transporter 4 messenger ribonucleic acid levels and insulin action in twins
-
Storgaard H, Poulsen P, Ling C, Groop L, Vaag AA (2006) Genetic and nongenetic determinants of skeletal muscle glucose transporter 4 messenger ribonucleic acid levels and insulin action in twins. J Clin Endocrinol Metab 91:702-708
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 702-708
-
-
Storgaard, H.1
Poulsen, P.2
Ling, C.3
Groop, L.4
Vaag, A.A.5
-
36
-
-
12244264435
-
Genetic Power Calculator: Design of linkage and association genetic mapping studies of complex traits
-
Purcell S, Cherny SS, Sham PC (2003) Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19:149-150
-
(2003)
Bioinformatics
, vol.19
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
38
-
-
0345305404
-
Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status
-
Bruce CR, Anderson MJ, Carey AL et al (2003) Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. J Clin Endocrinol Metab 88:5444-5451
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5444-5451
-
-
Bruce, C.R.1
Anderson, M.J.2
Carey, A.L.3
-
39
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S et al (2003) Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300:1140-1142
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
-
40
-
-
0024580556
-
Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in ageing
-
Trounce I, Byrne E, Marzuki S (1989) Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing. Lancet 1:637-639
-
(1989)
Lancet
, vol.1
, pp. 637-639
-
-
Trounce, I.1
Byrne, E.2
Marzuki, S.3
-
41
-
-
33746621756
-
Transcriptional profiling of aging in human muscle reveals a common aging signature
-
Zahn JM, Sonu R, Vogel H et al (2006) Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet 2:e115
-
(2006)
PLoS Genet
, vol.2
, pp. 115
-
-
Zahn, J.M.1
Sonu, R.2
Vogel, H.3
-
42
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies several additional susceptibility loci for type 2 diabetes
-
for the DIAGRAM consortium DOI 10.1038/ng.120
-
Zeggini E, Scott LJ, Saxena R, Voight BF for the DIAGRAM consortium (2008) Meta-analysis of genome-wide association data and large-scale replication identifies several additional susceptibility loci for type 2 diabetes. Nat Genet DOI 10.1038/ng.120
-
(2008)
Nat Genet
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
-
43
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R et al (2006) DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 38:1378-1385
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
-
44
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB et al (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 39:457-466
-
(2007)
Nat Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
46
-
-
0037066621
-
Genomic organization and promoter regulation of human cytochrome c oxidase subunit VII heart/muscle isoform (COX7AH)
-
Yu M, Jaradat SA, Grossman LI (2002) Genomic organization and promoter regulation of human cytochrome c oxidase subunit VII heart/muscle isoform (COX7AH). Biochim Biophys Acta 1574:345-353
-
(2002)
Biochim Biophys Acta
, vol.1574
, pp. 345-353
-
-
Yu, M.1
Jaradat, S.A.2
Grossman, L.I.3
-
47
-
-
34447625911
-
Epigenetics and aging: The targets and the marks
-
Fraga MF, Esteller M (2007) Epigenetics and aging: the targets and the marks. Trends Genet 23:413-418
-
(2007)
Trends Genet
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
48
-
-
34247473478
-
The epigenetic basis of twin discordance in age-related diseases
-
Poulsen P, Esteller M, Vaag A, Fraga MF (2007) The epigenetic basis of twin discordance in age-related diseases. Pediatr Res 61:38R-42R
-
(2007)
Pediatr Res
, vol.61
-
-
Poulsen, P.1
Esteller, M.2
Vaag, A.3
Fraga, M.F.4
-
49
-
-
0036328026
-
Role of DNA methylation in the regulation of cell function: Autoimmunity, aging and cancer
-
Richardson BC (2002) Role of DNA methylation in the regulation of cell function: autoimmunity, aging and cancer. J Nutr 132:2401S-2405S
-
(2002)
J Nutr
, vol.132
-
-
Richardson, B.C.1
-
50
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF et al (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 102:10604-10609
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
|