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Volumn 14, Issue 3, 2016, Pages 506-519

KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GLYCINE; HISTONE DEMETHYLASE; HISTONE H3; KDM4C PROTEIN; SERINE; UNCLASSIFIED DRUG; AMINO ACID; ATF4 PROTEIN, HUMAN; FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, HUMAN; HISTONE; HOMEODOMAIN PROTEIN; HOXC9 PROTEIN, HUMAN; KDM4C PROTEIN, HUMAN; MESSENGER RNA; PHOSPHOGLYCERATE DEHYDROGENASE; SMALL INTERFERING RNA;

EID: 84953327405     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.053     Document Type: Article
Times cited : (116)

References (60)
  • 1
    • 34447121352 scopus 로고    scopus 로고
    • Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids
    • Adams C.M. Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids. J. Biol. Chem. 2007, 282:16744-16753.
    • (2007) J. Biol. Chem. , vol.282 , pp. 16744-16753
    • Adams, C.M.1
  • 4
    • 84866782195 scopus 로고    scopus 로고
    • Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism
    • Baird T.D., Wek R.C. Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism. Adv. Nutr. 2012, 3:307-321.
    • (2012) Adv. Nutr. , vol.3 , pp. 307-321
    • Baird, T.D.1    Wek, R.C.2
  • 6
    • 84877861510 scopus 로고    scopus 로고
    • KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells
    • Berry W.L., Janknecht R. KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells. Cancer Res. 2013, 73:2936-2942.
    • (2013) Cancer Res. , vol.73 , pp. 2936-2942
    • Berry, W.L.1    Janknecht, R.2
  • 7
    • 84870375316 scopus 로고    scopus 로고
    • Histone lysine methylation dynamics: establishment, regulation, and biological impact
    • Black J.C., Van Rechem C., Whetstine J.R. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol. Cell 2012, 48:491-507.
    • (2012) Mol. Cell , vol.48 , pp. 491-507
    • Black, J.C.1    Van Rechem, C.2    Whetstine, J.R.3
  • 11
    • 80052775587 scopus 로고    scopus 로고
    • Serine metabolism: some tumors take the road less traveled
    • DeBerardinis R.J. Serine metabolism: some tumors take the road less traveled. Cell Metab. 2011, 14:285-286.
    • (2011) Cell Metab. , vol.14 , pp. 285-286
    • DeBerardinis, R.J.1
  • 12
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis R.J., Lum J.J., Hatzivassiliou G., Thompson C.B. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008, 7:11-20.
    • (2008) Cell Metab. , vol.7 , pp. 11-20
    • DeBerardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 13
    • 77958472998 scopus 로고    scopus 로고
    • Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response
    • Dey S., Baird T.D., Zhou D., Palam L.R., Spandau D.F., Wek R.C. Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response. J. Biol. Chem. 2010, 285:33165-33174.
    • (2010) J. Biol. Chem. , vol.285 , pp. 33165-33174
    • Dey, S.1    Baird, T.D.2    Zhou, D.3    Palam, L.R.4    Spandau, D.F.5    Wek, R.C.6
  • 14
    • 84889684498 scopus 로고    scopus 로고
    • The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation
    • Ding J., Li T., Wang X., Zhao E., Choi J.H., Yang L., Zha Y., Dong Z., Huang S., Asara J.M., et al. The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation. Cell Metab. 2013, 18:896-907.
    • (2013) Cell Metab. , vol.18 , pp. 896-907
    • Ding, J.1    Li, T.2    Wang, X.3    Zhao, E.4    Choi, J.H.5    Yang, L.6    Zha, Y.7    Dong, Z.8    Huang, S.9    Asara, J.M.10
  • 15
    • 33644670527 scopus 로고    scopus 로고
    • Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components
    • Ehrbrecht A., Müller U., Wolter M., Hoischen A., Koch A., Radlwimmer B., Actor B., Mincheva A., Pietsch T., Lichter P., et al. Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components. J. Pathol. 2006, 208:554-563.
    • (2006) J. Pathol. , vol.208 , pp. 554-563
    • Ehrbrecht, A.1    Müller, U.2    Wolter, M.3    Hoischen, A.4    Koch, A.5    Radlwimmer, B.6    Actor, B.7    Mincheva, A.8    Pietsch, T.9    Lichter, P.10
  • 17
    • 84891715569 scopus 로고    scopus 로고
    • Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth
    • Gregory B.L., Cheung V.G. Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth. Genome Res. 2014, 24:52-63.
    • (2014) Genome Res. , vol.24 , pp. 52-63
    • Gregory, B.L.1    Cheung, V.G.2
  • 18
    • 84886812954 scopus 로고    scopus 로고
    • The nexus of chromatin regulation and intermediary metabolism
    • Gut P., Verdin E. The nexus of chromatin regulation and intermediary metabolism. Nature 2013, 502:489-498.
    • (2013) Nature , vol.502 , pp. 489-498
    • Gut, P.1    Verdin, E.2
  • 20
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 21
    • 0038682500 scopus 로고    scopus 로고
    • Amino acid transporters: roles in amino acid sensing and signalling in animal cells
    • Hyde R., Taylor P.M., Hundal H.S. Amino acid transporters: roles in amino acid sensing and signalling in animal cells. Biochem. J. 2003, 373:1-18.
    • (2003) Biochem. J. , vol.373 , pp. 1-18
    • Hyde, R.1    Taylor, P.M.2    Hundal, H.S.3
  • 22
    • 33646826162 scopus 로고    scopus 로고
    • Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C
    • Italiano A., Attias R., Aurias A., Pérot G., Burel-Vandenbos F., Otto J., Venissac N., Pedeutour F. Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C. Cancer Genet. Cytogenet. 2006, 167:122-130.
    • (2006) Cancer Genet. Cytogenet. , vol.167 , pp. 122-130
    • Italiano, A.1    Attias, R.2    Aurias, A.3    Pérot, G.4    Burel-Vandenbos, F.5    Otto, J.6    Venissac, N.7    Pedeutour, F.8
  • 24
    • 84875755814 scopus 로고    scopus 로고
    • Influence of metabolism on epigenetics and disease
    • Kaelin W.G., McKnight S.L. Influence of metabolism on epigenetics and disease. Cell 2013, 153:56-69.
    • (2013) Cell , vol.153 , pp. 56-69
    • Kaelin, W.G.1    McKnight, S.L.2
  • 25
    • 84862017246 scopus 로고    scopus 로고
    • Resurgence of serine: an often neglected but indispensable amino Acid
    • Kalhan S.C., Hanson R.W. Resurgence of serine: an often neglected but indispensable amino Acid. J. Biol. Chem. 2012, 287:19786-19791.
    • (2012) J. Biol. Chem. , vol.287 , pp. 19786-19791
    • Kalhan, S.C.1    Hanson, R.W.2
  • 26
    • 84856090681 scopus 로고    scopus 로고
    • Connecting threads: epigenetics and metabolism
    • Katada S., Imhof A., Sassone-Corsi P. Connecting threads: epigenetics and metabolism. Cell 2012, 148:24-28.
    • (2012) Cell , vol.148 , pp. 24-28
    • Katada, S.1    Imhof, A.2    Sassone-Corsi, P.3
  • 27
    • 72049124015 scopus 로고    scopus 로고
    • ATF4-dependent transcription mediates signaling of amino acid limitation
    • Kilberg M.S., Shan J., Su N. ATF4-dependent transcription mediates signaling of amino acid limitation. Trends Endocrinol. Metab. 2009, 20:436-443.
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 436-443
    • Kilberg, M.S.1    Shan, J.2    Su, N.3
  • 28
    • 79959409830 scopus 로고    scopus 로고
    • Amino acid signaling in TOR activation
    • Kim J., Guan K.L. Amino acid signaling in TOR activation. Annu. Rev. Biochem. 2011, 80:1001-1032.
    • (2011) Annu. Rev. Biochem. , vol.80 , pp. 1001-1032
    • Kim, J.1    Guan, K.L.2
  • 30
    • 84903155824 scopus 로고    scopus 로고
    • KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis
    • Kupershmit I., Khoury-Haddad H., Awwad S.W., Guttmann-Raviv N., Ayoub N. KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis. Nucleic Acids Res. 2014, 42:6168-6182.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 6168-6182
    • Kupershmit, I.1    Khoury-Haddad, H.2    Awwad, S.W.3    Guttmann-Raviv, N.4    Ayoub, N.5
  • 31
    • 84903155987 scopus 로고    scopus 로고
    • Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential
    • Labbé R.M., Holowatyj A., Yang Z.Q. Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential. Am. J. Transl. Res. 2013, 6:1-15.
    • (2013) Am. J. Transl. Res. , vol.6 , pp. 1-15
    • Labbé, R.M.1    Holowatyj, A.2    Yang, Z.Q.3
  • 32
  • 33
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante M., Sabatini D.M. mTOR signaling in growth control and disease. Cell 2012, 149:274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 34
    • 72449186524 scopus 로고    scopus 로고
    • Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
    • Liu G., Bollig-Fischer A., Kreike B., van de Vijver M.J., Abrams J., Ethier S.P., Yang Z.Q. Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer. Oncogene 2009, 28:4491-4500.
    • (2009) Oncogene , vol.28 , pp. 4491-4500
    • Liu, G.1    Bollig-Fischer, A.2    Kreike, B.3    van de Vijver, M.J.4    Abrams, J.5    Ethier, S.P.6    Yang, Z.Q.7
  • 35
    • 84881177291 scopus 로고    scopus 로고
    • Serine, glycine and one-carbon units: cancer metabolism in full circle
    • Locasale J.W. Serine, glycine and one-carbon units: cancer metabolism in full circle. Nat. Rev. Cancer 2013, 13:572-583.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 572-583
    • Locasale, J.W.1
  • 37
    • 84863534997 scopus 로고    scopus 로고
    • Metabolic regulation of epigenetics
    • Lu C., Thompson C.B. Metabolic regulation of epigenetics. Cell Metab. 2012, 16:9-17.
    • (2012) Cell Metab. , vol.16 , pp. 9-17
    • Lu, C.1    Thompson, C.B.2
  • 40
    • 79958863552 scopus 로고    scopus 로고
    • HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma
    • Mao L., Ding J., Zha Y., Yang L., McCarthy B.A., King W., Cui H., Ding H.F. HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma. Cancer Res. 2011, 71:4314-4324.
    • (2011) Cancer Res. , vol.71 , pp. 4314-4324
    • Mao, L.1    Ding, J.2    Zha, Y.3    Yang, L.4    McCarthy, B.A.5    King, W.6    Cui, H.7    Ding, H.F.8
  • 41
    • 77953644347 scopus 로고    scopus 로고
    • Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases
    • Mosammaparast N., Shi Y. Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu. Rev. Biochem. 2010, 79:155-179.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 155-179
    • Mosammaparast, N.1    Shi, Y.2
  • 43
    • 84894283946 scopus 로고    scopus 로고
    • The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development
    • Pedersen M.T., Agger K., Laugesen A., Johansen J.V., Cloos P.A., Christensen J., Helin K. The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development. Mol. Cell. Biol. 2014, 34:1031-1045.
    • (2014) Mol. Cell. Biol. , vol.34 , pp. 1031-1045
    • Pedersen, M.T.1    Agger, K.2    Laugesen, A.3    Johansen, J.V.4    Cloos, P.A.5    Christensen, J.6    Helin, K.7
  • 46
    • 84881131933 scopus 로고    scopus 로고
    • The DREAM complex: master coordinator of cell cycle-dependent gene expression
    • Sadasivam S., DeCaprio J.A. The DREAM complex: master coordinator of cell cycle-dependent gene expression. Nat. Rev. Cancer 2013, 13:585-595.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 585-595
    • Sadasivam, S.1    DeCaprio, J.A.2
  • 47
    • 84869009687 scopus 로고    scopus 로고
    • How cancer metabolism is tuned for proliferation and vulnerable to disruption
    • Schulze A., Harris A.L. How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature 2012, 491:364-373.
    • (2012) Nature , vol.491 , pp. 364-373
    • Schulze, A.1    Harris, A.L.2
  • 49
    • 79955460159 scopus 로고    scopus 로고
    • H3K9 methyltransferase G9a and the related molecule GLP
    • Shinkai Y., Tachibana M. H3K9 methyltransferase G9a and the related molecule GLP. Genes Dev. 2011, 25:781-788.
    • (2011) Genes Dev. , vol.25 , pp. 781-788
    • Shinkai, Y.1    Tachibana, M.2
  • 51
    • 0037025396 scopus 로고    scopus 로고
    • ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene
    • Siu F., Bain P.J., LeBlanc-Chaffin R., Chen H., Kilberg M.S. ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem. 2002, 277:24120-24127.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24120-24127
    • Siu, F.1    Bain, P.J.2    LeBlanc-Chaffin, R.3    Chen, H.4    Kilberg, M.S.5
  • 53
    • 77957666255 scopus 로고    scopus 로고
    • Histone methyl transferases and demethylases; can they link metabolism and transcription?
    • Teperino R., Schoonjans K., Auwerx J. Histone methyl transferases and demethylases; can they link metabolism and transcription?. Cell Metab. 2010, 12:321-327.
    • (2010) Cell Metab. , vol.12 , pp. 321-327
    • Teperino, R.1    Schoonjans, K.2    Auwerx, J.3
  • 55
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 56
    • 58149198591 scopus 로고    scopus 로고
    • Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3
    • Vinatzer U., Gollinger M., Müllauer L., Raderer M., Chott A., Streubel B. Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3. Clin. Cancer Res. 2008, 14:6426-6431.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6426-6431
    • Vinatzer, U.1    Gollinger, M.2    Müllauer, L.3    Raderer, M.4    Chott, A.5    Streubel, B.6
  • 57
    • 84888096972 scopus 로고    scopus 로고
    • HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation
    • Wang X., Choi J.H., Ding J., Yang L., Ngoka L.C., Lee E.J., Zha Y., Mao L., Jin B., Ren M., et al. HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation. BMC Genomics 2013, 14:830.
    • (2013) BMC Genomics , vol.14 , pp. 830
    • Wang, X.1    Choi, J.H.2    Ding, J.3    Yang, L.4    Ngoka, L.C.5    Lee, E.J.6    Zha, Y.7    Mao, L.8    Jin, B.9    Ren, M.10


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