A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates

FASEB Journal

Volumn 26, Issue 12, 2012, Pages 5106-5114

  Suter, Melissa A ^a   Chen, Aishe ^a   Burdine, Marie S ^b   Choudhury, Mahua ^c   Harris, R Alan ^a   Lane, Robert H ^d   Friedman, Jacob E ^c   Grove, Kevin L ^e   Tackett, Alan J ^b   Aagaard, Kjersti M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Developmental origins of adult disease; Epigenetics; Histone modification; NAFLD; Sirtuins

Indexed keywords

ACYL COENZYME A DESATURASE; ACYLTRANSFERASE; CHOLESTEROL 7ALPHA MONOOXYGENASE; DELETED IN BREAST CANCER 1 PROTEIN; FATTY ACID SYNTHASE; HISTIDINE; HISTONE DEACETYLASE; HISTONE H3; LYSINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN DEACETYLASE; REGULATOR PROTEIN; SIRTUIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CELL METABOLISM; COMPLEX FORMATION; CONTROLLED STUDY; DEACETYLATION; DIET; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME SUBSTRATE; EPIGENETICS; EX VIVO STUDY; FEMALE; FETUS; GENE EXPRESSION; HISTONE ACETYLATION; IN VITRO STUDY; LIPID DIET; LIVER; MATERNAL HIGH FAT DIET; MATERNAL OBESITY; MEDIATOR; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS;

ACETYLATION; ANIMALS; BLOTTING, WESTERN; CATALYTIC DOMAIN; COS CELLS; DIET, HIGH-FAT; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONE DEACETYLASES; HISTONES; LIVER; LYSINE; MACACA; MALE; MASS SPECTROMETRY; MUTATION; P300-CBP TRANSCRIPTION FACTORS; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIRTUIN 1; SUBSTRATE SPECIFICITY;

PRIMATES;

EID: 84870316797     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-212878     Document Type: Article

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