Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

Cell Metabolism

Volumn 22, Issue 5, 2015, Pages 861-873

  Mentch, Samantha J ^a,e,f   Mehrmohamadi, Mahya ^a,e,f   Huang, Lei ^b   Liu, Xiaojing ^a   Gupta, Diwakar ^a   Mattocks, Dwight ^c   Gómez Padilla, Paola ^a   Ables, Gene ^c   Bamman, Marcas M ^d   Thalacker Mercer, Anna E ^a   Nichenametla, Sailendra N ^c   Locasale, Jason W ^a,b,e,f  

^a Department of Obstetrics Gynecology   (United States)

^b Plant Breeding and Genetics Section in the School of Integrative Plant Science   (United States)

^c Orentreich Foundation for the Advancement of Science Inc   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e DUKE CANCER INSTITUTE   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chromatin biology; epigenetics; metabolomics; one carbon metabolism

Indexed keywords

BETAINE; CARBON; DIMETHYLGLYCINE; HOMOCYSTEINE; METHIONINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; SARCOSINE; CHROMATIN; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; TRANSFERASE;

ADULT; AMINO ACID METABOLISM; ARTICLE; BINDING AFFINITY; BODY COMPOSITION; CARBON CYCLE; CARBON METABOLISM; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR STRESS RESPONSE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DIETARY INTAKE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEEDBACK SYSTEM; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLYCOLYSIS; HISTONE METHYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KETOGENESIS; MASS SPECTROMETRY; METABOLOMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTAKE; QUANTITATIVE ANALYSIS; RNA SEQUENCE; SIGNAL TRANSDUCTION; TITRIMETRY; TRANSCRIPTION INITIATION SITE; ANIMAL; CHROMATIN; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; LIVER; METABOLISM; METHYLATION; MOUSE;

ANIMALS; CARBON; CHROMATIN; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; LIVER; METHIONINE; METHYLATION; MICE; ONE-CARBON GROUP TRANSFERASES; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE;

EID: 84948412126     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.08.024     Document Type: Article

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