Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes

Diabetes

Volumn 63, Issue 9, 2014, Pages 2962-2976

  Nilsson, Emma ^a,b   Jansson, Per Anders ^c   Perfilyev, Alexander ^a   Volkov, Petr ^a   Pedersen, Maria ^d   Svensson, Maria K ^e   Poulsen, Pernille ^f   Ribel Madsen, Rasmus ^b   Pedersen, Nancy L ^g   Almgren, Peter ^a   Fadista, João ^a   Rönn, Tina ^a   Pedersen, Bente Klarlund ^d   Scheele, Camilla ^d   Vaag, Allan ^b   Ling, Charlotte ^a  

^a LUND UNIVERSITY   (Sweden)

^b Rigshospitalet   (Denmark)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^f NOVO NORDISK A S   (Denmark)

^g KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CARBOHYDRATE; GLYCAN;

ADIPOSE TISSUE; ADULT; AGED; AMINO ACID METABOLISM; ARTICLE; CARBOHYDRATE METABOLISM; CASE CONTROL STUDY; CCL18 GENE; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; CORRELATION ANALYSIS; DIABETIC PATIENT; DNA METHYLATION; ELOVL6 GENE; EPIGENETICS; FADS1 GENE; FEMALE; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GYS2 GENE; HERITABILITY; HUMAN; IL1RN GENE; INFLAMMATION; IRS1 GENE; KCNQ1 GENE; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; METABOLISM; MOLECULAR BIOLOGY; MONOZYGOTIC TWINS; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE PHOSPHORYLATION; PPARG GENE; PRIORITY JOURNAL; SPP1 GENE; TCF7L2 GENE; TWIN DISCORDANCE; VEGFA GENE;

ADIPOSE TISSUE; AGED; CASE-CONTROL STUDIES; COHORT STUDIES; CPG ISLANDS; DIABETES MELLITUS, TYPE 2; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; HUMANS; MALE; MIDDLE AGED; PANNICULITIS; TRANSCRIPTOME; TWINS, MONOZYGOTIC;

EID: 84906707442     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1459     Document Type: Article

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