Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 49, 2008, Pages 19229-19234

  Lee, Jeongkyung ^a   Saha, Pradip K ^a   Yang, Qi Heng ^c   Lee, Seunghee ^a   Jung, Yoon Park ^b   Suh, Yousin ^b   Lee, Soo Kyung ^a   Chan, Lawrence ^a   Roeder, Robert G ^c   Lee, Jae W ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Activating signal cointegrator 2; ASCOM; Coactivator; Peroxisome proliferator activated receptor ; Transcription

Indexed keywords

ACTIVATING SIGNAL COINTEGRATOR 2; METHYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN MLL3; PROTEIN MLL4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; GENE MUTATION; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING;

ADIPOCYTES, WHITE; ADIPOGENESIS; ADIPOSE TISSUE, WHITE; ANIMALS; BIRTH WEIGHT; DIETARY FATS; FEMALE; HISTONE-LYSINE N-METHYLTRANSFERASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; METHYLATION; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NIH 3T3 CELLS; OBESITY; PHENOTYPE; PPAR GAMMA;

MUS;

EID: 58049206724     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810100105     Document Type: Article

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