Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: Coupling protein O-GlcNAcylation to transcriptional repression

Cell

Volumn 110, Issue 1, 2002, Pages 69-80

  Yang, Xiaoyong ^a   Zhang, Fengxue ^a   Kudlow, Jeffrey E ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSAMINE DERIVATIVE; HISTONE DEACETYLASE; O LINKED N ACETYLGLUCOSAMINE; O LINKED N ACETYLGLUCOSAMINE TRANSFERASE; PROTEIN; REPRESSOR PROTEIN; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SIN3A; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CONTROLLED STUDY; DEACETYLATION; ENZYME ANALYSIS; GENE SILENCING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN TARGETING;

ANIMALIA;

EID: 0037067659     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00810-3     Document Type: Article

References (69)

1. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter
2. NuRD and SIN3 histone deacetylase complexes in development
3. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
4. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
5. Molecular biology. The histone modification circus
6. Retinoblastoma protein recruits histone deacetylase to repress transcription
7. Co-repressors 2000
8. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase
9. HATs on and beyond chromatin
10. Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter
11. Reversible phosphorylation of the C-terminal domain of RNA polymerase II
12. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
13. The coregulator exchange in transcriptional functions of nuclear receptors
14. Histone acetylation and chromatin remodeling
15. Three proteins define a class of human histone deacetylases related to yeast Hda1p
16. Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins
17. Histone deacetylase activity is required for full transcriptional repression by mSin3A
18. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
19. Transcriptional repression directed by the yeast α 2 protein in vitro
20. The regulation of transcription by phosphorylation
21. O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
22. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
23. Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo
24. Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
25. Isolation and characterization of mammalian HDAC10, a novel histone deacetylase
26. Phosphorylation meets ubiquitination: The control of NF-[κ]B activity
27. Glycosylation of chromosomal proteins: Localization of O-linked N-acetylglucosamine in Drosophila chromatin
28. RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc
29. Histone acetylases and deacetylases in cell proliferation
30. Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats
31. Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats
32. Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1
33. Role of histone deacetylase complexes in the regulation of chromatin metabolism
34. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
35. SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors
36. Tetratrico peptide repeat interactions: To TPR or not to TPR?
37. O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats
38. Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity
39. Rb interacts with histone deacetylase to repress transcription
40. Enzymatic activities of Sir2 and chromatin silencing
41. Arginine methylation of STAT1 modulates IFNα/β-induced transcription
42. Chromatin remodeling in development and differentiation
43. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
44. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
45. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
46. Histone deacetylases: Silencers for hire
47. Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila
48. Accessibility of alpha 2-repressed promoters to the activator Gal4
49. Rad6-dependent ubiquitination of histone H2B in yeast
50. O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions
51. Structure of O-linked GlcNAc transferase: Mediator of glycan-dependent signaling
52. Silenced chromatin is permissive to activator binding and PIC recruitment
53. The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
54. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
55. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes
56. Turning genes off by Ssn6-Tup1: A conserved system of transcriptional repression in eukaryotes
57. The language of covalent histone modifications
58. An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro
59. Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1
60. Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters
61. HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
62. Ssn6-Tup1 interacts with class I histone deacetylases required for repression
63. Glycosylation of nucleocytoplasmic proteins: Signal transduction and O-GlcNAc
64. Co-repressor complexes and remodelling chromatin for repression
65. Transcriptional repression by the SMRT-mSin3 corepressor: Multiple interactions, multiple mechanisms, and a potential role for TFIIB
66. TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast
67. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3
68. O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability
69. Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex