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Volumn 6, Issue 1, 2010, Pages 24-32

Role of histone methylation and demethylation in adipogenesis and obesity

Author keywords

Adipogenesis; Epigenetics; Histone lysine methyltransferase (HKMT); Metabolic syndrome; Obesity; Peroxisome proliferator activated receptor (PPAR); PR Set7; Setd8; Setdb1; Wnt

Indexed keywords

BETA CATENIN; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 1; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; WNT PROTEIN;

EID: 77953515715     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.4161/org.6.1.11121     Document Type: Review
Times cited : (92)

References (80)
  • 1
    • 0035542555 scopus 로고    scopus 로고
    • Transcriptional regulation in the context of chromatin structure
    • Wolffe AP. Transcriptional regulation in the context of chromatin structure. Essays Biochem 2001; 37:45-57. (Pubitemid 33402955)
    • (2001) Essays in Biochemistry , vol.37 , pp. 45-57
    • Wolffe, A.P.1
  • 2
    • 0033529565 scopus 로고    scopus 로고
    • Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
    • DOI 10.1016/S0092-8674(00)81958-3
    • Kornberg RD, Lorch Y. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome. Cell 1999; 98:285-94. (Pubitemid 29380564)
    • (1999) Cell , vol.98 , Issue.3 , pp. 285-294
    • Kornberg, R.D.1    Lorch, Y.2
  • 3
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. Translating the histone code. Science 2001; 293:1074-80.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 5
    • 15744396813 scopus 로고    scopus 로고
    • The key to development: Interpreting the histone code?
    • Margueron R, Trojer P, Reinberg D. The key to development: interpreting the histone code? Curr Opin Genet Dev 2005; 15:163-76.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 163-176
    • Margueron, R.1    Trojer, P.2    Reinberg, D.3
  • 6
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • DOI 10.1038/nrm1761, PII N1761
    • Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 2005; 6:838-49. (Pubitemid 41568733)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.11 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 7
    • 20844450998 scopus 로고    scopus 로고
    • Arginine methylation: An emerging regulator of protein function
    • DOI 10.1016/j.molcel.2005.04.003, PII S1097276505012475
    • Bedford MT, Richard S. Arginine methylation an emerging regulator of protein function. Mol Cell 2005; 18:263-72. (Pubitemid 41350532)
    • (2005) Molecular Cell , vol.18 , Issue.3 , pp. 263-272
    • Bedford, M.T.1    Richard, S.2
  • 8
    • 24144475284 scopus 로고    scopus 로고
    • Reversing histone methylation
    • Bannister AJ, Kouzarides T. Reversing histone methylation. Nature 2005; 436:1103-6.
    • (2005) Nature , vol.436 , pp. 1103-1106
    • Bannister, A.J.1    Kouzarides, T.2
  • 9
    • 0035282573 scopus 로고    scopus 로고
    • Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
    • DOI 10.1038/35065132
    • Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 2001; 410:116-20. (Pubitemid 32225847)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 116-120
    • Lachner, M.1    O'Carroll, D.2    Rea, S.3    Mechtler, K.4    Jenuwein, T.5
  • 10
    • 33747455678 scopus 로고    scopus 로고
    • JmjC-domain-containing proteins and histone demethylation
    • Klose RJ, Kallin EM, Zhang Y. JmjC-domain-containing proteins and histone demethylation. Nat Rev 2006; 7:715-27.
    • (2006) Nat Rev , vol.7 , pp. 715-727
    • Klose, R.J.1    Kallin, E.M.2    Zhang, Y.3
  • 11
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006; 444:847-53.
    • (2006) Nature , vol.444 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 12
    • 44149120984 scopus 로고    scopus 로고
    • Molecular determinants of brown adipocyte formation and function
    • Farmer SR. Molecular determinants of brown adipocyte formation and function. Genes Dev 2008; 22:1269-75.
    • (2008) Genes Dev , vol.22 , pp. 1269-1275
    • Farmer, S.R.1
  • 13
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • DOI 10.1079/BJN20041213
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92:347-55. (Pubitemid 40277057)
    • (2004) British Journal of Nutrition , vol.92 , Issue.3 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 14
    • 0034611675 scopus 로고    scopus 로고
    • Obesity in the new millennium
    • Friedman JM. Obesity in the new millennium. Nature 2000; 404:632-4.
    • (2000) Nature , vol.404 , pp. 632-634
    • Friedman, J.M.1
  • 16
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer SR. Transcriptional control of adipocyte formation. Cell Metab 2006; 4:263-73.
    • (2006) Cell Metab , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 17
    • 0029102676 scopus 로고
    • Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPARgamma) gene: Alternative promoter use and different splicing yield two mPPARgamma isoforms
    • Zhu Y, Qi C, Korenberg JR, Chen XN, Noya D, Rao MS, Reddy JK. Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPARgamma) gene: alternative promoter use and different splicing yield two mPPARgamma isoforms. Proc Natl Acad Sci USA 1995; 92:7921-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7921-7925
    • Zhu, Y.1    Qi, C.2    Korenberg, J.R.3    Chen, X.N.4    Noya, D.5    Rao, M.S.6    Reddy, J.K.7
  • 18
    • 0033546003 scopus 로고    scopus 로고
    • Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors p18(INK4c) and p21(Waf1/Cip1), during adipogenesis
    • Morrison RF, Farmer SR. Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c) and p21(Waf1/Cip1), during adipogenesis. J Biol Chem 1999; 274:17088-97.
    • (1999) J Biol Chem , Issue.274 , pp. 17088-17097
    • Morrison, R.F.1    Farmer, S.R.2
  • 19
    • 0034613375 scopus 로고    scopus 로고
    • Function of GATA transcription factors in preadipocyte-adipocyte transition
    • Tong Q, Dalgin G, Xu H, Ting CN, Leiden JM, Hotamisligil GS. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science 2000; 290:134-8.
    • (2000) Science , vol.290 , pp. 134-138
    • Tong, Q.1    Dalgin, G.2    Xu, H.3    Ting, C.N.4    Leiden, J.M.5    Hotamisligil, G.S.6
  • 20
    • 41449116010 scopus 로고    scopus 로고
    • Transcriptional regulation of adipogenesis by KLF4
    • Birsoy K, Chen Z, Friedman J. Transcriptional regulation of adipogenesis by KLF4. Cell Metab 2008; 7:339-47.
    • (2008) Cell Metab , vol.7 , pp. 339-347
    • Birsoy, K.1    Chen, Z.2    Friedman, J.3
  • 21
    • 20144389501 scopus 로고    scopus 로고
    • Kruppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation
    • Oishi Y, Manabe I, Tobe K, Tsushima K, Shindo T, Fujiu K, et al. Kruppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation. Cell Metab 2005; 1:27-39.
    • (2005) Cell Metab , vol.1 , pp. 27-39
    • Oishi, Y.1    Manabe, I.2    Tobe, K.3    Tsushima, K.4    Shindo, T.5    Fujiu, K.6
  • 22
    • 20144387014 scopus 로고    scopus 로고
    • Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis
    • Mori T, Sakaue H, Iguchi H, Gomi H, Okada Y, Takashima Y, et al. Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis. J Biol Chem 2005; 280:12867-75.
    • (2005) J Biol Chem , vol.280 , pp. 12867-12875
    • Mori, T.1    Sakaue, H.2    Iguchi, H.3    Gomi, H.4    Okada, Y.5    Takashima, Y.6
  • 23
    • 40649091407 scopus 로고    scopus 로고
    • The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis
    • Xu Z, Yu S, Hsu C-H, Eguchi J, Rosen ED. The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis. Proc Natl Acad Sci USA 2008; 0707082105.
    • (2008) Proc Natl Acad Sci USA , pp. 0707082105
    • Xu, Z.1    Yu, S.2    Hsu, C.-H.3    Eguchi, J.4    Rosen, E.D.5
  • 24
    • 65249138877 scopus 로고    scopus 로고
    • COUP-TFII acts downstream of Wnt/β-catenin signal to silence PPARγ gene expression and repress adipogenesis
    • Okamura M, Kudo H, Wakabayashi K, Tanaka T, Nonaka A, Uchida A, et al. COUP-TFII acts downstream of Wnt/β-catenin signal to silence PPARγ gene expression and repress adipogenesis. Proc Natl Acad Sci USA 2009; 106:5819-24.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5819-5824
    • Okamura, M.1    Kudo, H.2    Wakabayashi, K.3    Tanaka, T.4    Nonaka, A.5    Uchida, A.6
  • 25
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 2006; 7:885-96.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 885-896
    • Rosen, E.D.1    MacDougald, O.A.2
  • 26
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33:245-54.
    • (2003) Nat Genet , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 27
    • 67650070982 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop
    • Wakabayashi K, Okamura M, Tsutsumi S, Nishikawa NS, Tanaka T, Sakakibara I, et al. The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop. Mol Cell Biol 2009; 29:3544-55.
    • (2009) Mol Cell Biol , vol.29 , pp. 3544-3555
    • Wakabayashi, K.1    Okamura, M.2    Tsutsumi, S.3    Nishikawa, N.S.4    Tanaka, T.5    Sakakibara, I.6
  • 28
    • 33644701666 scopus 로고    scopus 로고
    • Histone H4-lysine 20 monomethylation is increased in promoter and coding regions of active genes and correlates with hyperacetylation
    • DOI 10.1074/jbc.M505563200
    • Talasz H, Lindner HH, Sarg B, Helliger W. Histone H4-lysine 20 monomethylation is increased in promoter and coding regions of active genes and correlates with hyperacetylation. J Biol Chem 2005; 280:38814-22. (Pubitemid 43853784)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38814-38822
    • Talasz, H.1    Lindner, H.H.2    Sarg, B.3    Helliger, W.4
  • 29
    • 33845451555 scopus 로고    scopus 로고
    • Profile of histone lysine methylation across transcribed mammalian chromatin
    • DOI 10.1128/MCB.01529-06
    • Vakoc CR, Sachdeva MM, Wang H, Blobel GA. Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol 2006; 26:9185-95. (Pubitemid 44904415)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.24 , pp. 9185-9195
    • Vakoc, C.R.1    Sachdeva, M.M.2    Wang, H.3    Blobel, G.A.4
  • 31
    • 34249026300 scopus 로고    scopus 로고
    • High-Resolution Profiling of Histone Methylations in the Human Genome
    • DOI 10.1016/j.cell.2007.05.009, PII S0092867407006009
    • Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, et al. High-resolution profiling of histone methylations in the human genome. Cell 2007; 129:823-37. (Pubitemid 46802390)
    • (2007) Cell , vol.129 , Issue.4 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.-Y.4    Schones, D.E.5    Wang, Z.6    Wei, G.7    Chepelev, I.8    Zhao, K.9
  • 32
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y, et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001; 107:513-23.
    • (2001) Cell , vol.107 , pp. 513-523
    • Gong, Y.1
  • 34
    • 0037422571 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
    • Fujino T, et al. Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. Proc Natl Acad Sci USA 2003; 100:229-34.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 229-234
    • Fujino, T.1
  • 35
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127:469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 36
    • 35748960839 scopus 로고    scopus 로고
    • A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPARgamma transactivation
    • Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, et al. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPARgamma transactivation. Nat Cell Biol 2007; 9:1273-85.
    • (2007) Nat Cell Biol , vol.9 , pp. 1273-1285
    • Takada, I.1    Mihara, M.2    Suzawa, M.3    Ohtake, F.4    Kobayashi, S.5    Igarashi, M.6
  • 38
    • 0037089626 scopus 로고    scopus 로고
    • SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
    • DOI 10.1101/gad.973302
    • Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ, 3rd. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev 2002; 16:919-32. (Pubitemid 34408542)
    • (2002) Genes and Development , vol.16 , Issue.8 , pp. 919-932
    • Schultz, D.C.1    Ayyanathan, K.2    Negorev, D.3    Maul, G.G.4    Rauscher III, F.J.5
  • 39
    • 0141992115 scopus 로고    scopus 로고
    • MAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression
    • Wang H, An W, Cao R, Xia L, Erdjument-Bromage H, Chatton B, et al. mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol Cell 2003; 12:475-87.
    • (2003) Mol Cell , vol.12 , pp. 475-487
    • Wang, H.1    An, W.2    Cao, R.3    Xia, L.4    Erdjument-Bromage, H.5    Chatton, B.6
  • 40
    • 33846019277 scopus 로고    scopus 로고
    • Methylation of Lysine 4 on Histone H3: Intricacy of Writing and Reading a Single Epigenetic Mark
    • DOI 10.1016/j.molcel.2006.12.014, PII S1097276506008720
    • Ruthenburg AJ, Allis CD, Wysocka J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol Cell 2007; 25:15-30. (Pubitemid 46049068)
    • (2007) Molecular Cell , vol.25 , Issue.1 , pp. 15-30
    • Ruthenburg, A.J.1    Allis, C.D.2    Wysocka, J.3
  • 41
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
    • DOI 10.1146/annurev.biochem.75.103004.142422
    • Shilatifard A. Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem 2006; 75:243-69. (Pubitemid 44118033)
    • (2006) Annual Review of Biochemistry , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 42
    • 0037216704 scopus 로고    scopus 로고
    • Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins
    • Goo YH, Sohn YC, Kim DH, Kim SW, Kang MJ, Jung DJ, et al. Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Mol Cell Biol 2003; 23:140-9.
    • (2003) Mol Cell Biol , vol.23 , pp. 140-149
    • Goo, Y.H.1    Sohn, Y.C.2    Kim, D.H.3    Kim, S.W.4    Kang, M.J.5    Jung, D.J.6
  • 45
    • 20444417108 scopus 로고    scopus 로고
    • WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development
    • DOI 10.1016/j.cell.2005.03.036, PII S0092867405003557
    • Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 2005; 121:859-72. (Pubitemid 40806418)
    • (2005) Cell , vol.121 , Issue.6 , pp. 859-872
    • Wysocka, J.1    Swigut, T.2    Milne, T.A.3    Dou, Y.4    Zhang, X.5    Burlingame, A.L.6    Roeder, R.G.7    Brivanlou, A.H.8    Allis, C.D.9
  • 46
    • 22544446198 scopus 로고    scopus 로고
    • Nuclear hormone receptor coregulator: Role in hormone action, metabolism, growth and development
    • Mahajan MA, Samuels HH. Nuclear hormone receptor coregulator: role in hormone action, metabolism, growth and development. Endocr Rev 2005; 26:583-97.
    • (2005) Endocr Rev , vol.26 , pp. 583-597
    • Mahajan, M.A.1    Samuels, H.H.2
  • 50
    • 35148898348 scopus 로고    scopus 로고
    • A histone H3 lysine 27 demethylase regulates animal posterior development
    • Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, et al. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature 2007; 449:689-94.
    • (2007) Nature , vol.449 , pp. 689-694
    • Lan, F.1    Bayliss, P.E.2    Rinn, J.L.3    Whetstine, J.R.4    Wang, J.K.5    Chen, S.6
  • 51
    • 35348993743 scopus 로고    scopus 로고
    • Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
    • Lee MG, Villa R, Trojer P, Norman J, Yan KP, Reinberg D, et al. Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science 2007; 318:447-50.
    • (2007) Science , vol.318 , pp. 447-450
    • Lee, M.G.1    Villa, R.2    Trojer, P.3    Norman, J.4    Yan, K.P.5    Reinberg, D.6
  • 52
    • 35148867907 scopus 로고    scopus 로고
    • UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
    • Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 2007; 449:731-4.
    • (2007) Nature , vol.449 , pp. 731-734
    • Agger, K.1    Cloos, P.A.2    Christensen, J.3    Pasini, D.4    Rose, S.5    Rappsilber, J.6
  • 53
    • 36749082438 scopus 로고    scopus 로고
    • Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
    • Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc Natl Acad Sci USA 2007; 104:18439-44.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 18439-18444
    • Hong, S.1    Cho, Y.W.2    Yu, L.R.3    Yu, H.4    Veenstra, T.D.5    Ge, K.6
  • 54
    • 0037160140 scopus 로고    scopus 로고
    • Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality
    • DOI 10.1074/jbc.C200509200
    • Kuang SQ, Liao L, Zhang H, Pereira FA, Yuan Y, DeMayo FJ, et al. Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality. J Biol Chem 2002; 277:45356-60. (Pubitemid 36159143)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.47 , pp. 45356-45360
    • Kuang, S.-Q.1    Liao, L.2    Zhang, H.3    Pereira, F.A.4    Yuan, Y.5    DeMayo, F.J.6    Ko, L.7    Xu, J.8
  • 56
    • 0038153901 scopus 로고    scopus 로고
    • Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis
    • Qi C, Surapureddi S, Zhu YJ, Yu S, Kashireddy P, Rao MS, et al. Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis. J Biol Chem 2003; 278:25281-4.
    • (2003) J Biol Chem , vol.278 , pp. 25281-25284
    • Qi, C.1    Surapureddi, S.2    Zhu, Y.J.3    Yu, S.4    Kashireddy, P.5    Rao, M.S.6
  • 57
    • 0034811834 scopus 로고    scopus 로고
    • Functional interaction of transcriptional coactivator ASC-2 and C/EBPalpha in granulocyte differentiation of HL-60 promyelocytic cell
    • DOI 10.1006/bbrc.2001.4727
    • Hong S, Lee MY, Cheong J. Functional interaction of transcriptional coactivator ASC-2 and C/EBPalpha in granulocyte differentiation of HL-60 promyelocytic cell. Biochem Biophys Res Commun 2001; 282:1257-62. (Pubitemid 32912862)
    • (2001) Biochemical and Biophysical Research Communications , vol.282 , Issue.5 , pp. 1257-1262
    • Hong, S.1    Lee, M.Y.2    Cheong, J.3
  • 59
    • 58049206724 scopus 로고    scopus 로고
    • Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
    • Lee J, Saha PK, Yang QH, Lee S, Park JY, Suh Y, et al. Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc Natl Acad Sci USA 2008; 105:19229-34.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19229-19234
    • Lee, J.1    Saha, P.K.2    Yang, Q.H.3    Lee, S.4    Park, J.Y.5    Suh, Y.6
  • 60
    • 67649418447 scopus 로고    scopus 로고
    • Histone methylation regulator PTIP is required for PPARgamma and C/EBPalpha expression and adipogenesis
    • Cho YW, Hong S, Jin Q, Wang L, Lee JE, Gavrilova O, et al. Histone methylation regulator PTIP is required for PPARgamma and C/EBPalpha expression and adipogenesis. Cell Metab 2009; 10:27-39.
    • (2009) Cell Metab , vol.10 , pp. 27-39
    • Cho, Y.W.1    Hong, S.2    Jin, Q.3    Wang, L.4    Lee, J.E.5    Gavrilova, O.6
  • 61
    • 34248224882 scopus 로고    scopus 로고
    • Pax transactivation-domain interacting protein is required for urine concentration and osmotolerance in collecting duct epithelia
    • DOI 10.1681/ASN.2006060625
    • Kim D, Wang M, Cai Q, Brooks H, Dressler GR. Pax transactivation-domain interacting protein is required for urine concentration and osmotolerance in collecting duct epithelia. J Am Soc Nephrol 2007; 18:1458-65. (Pubitemid 46717512)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.5 , pp. 1458-1465
    • Kim, D.1    Wang, M.2    Cai, Q.3    Brooks, H.4    Dressler, G.R.5
  • 63
    • 9144229185 scopus 로고    scopus 로고
    • Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle
    • He W, Barak Y, Hevener A, Olson P, Liao D, Le J, et al. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci USA 2003; 100:15712-7.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15712-15717
    • He, W.1    Barak, Y.2    Hevener, A.3    Olson, P.4    Liao, D.5    Le, J.6
  • 64
    • 0027731309 scopus 로고
    • Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
    • Lowell BB, V SS, Hamann A, Lawitts JA, Himms-Hagen J, Boyer BB, et al. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 1993; 366:740-2.
    • (1993) Nature , vol.366 , pp. 740-742
    • Lowell, B.B.1    V, S.S.2    Hamann, A.3    Lawitts, J.A.4    Himms-Hagen, J.5    Boyer, B.B.6
  • 65
    • 44149113548 scopus 로고    scopus 로고
    • Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
    • Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, et al. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev 2008; 22:1397-409.
    • (2008) Genes Dev , vol.22 , pp. 1397-1409
    • Kajimura, S.1    Seale, P.2    Tomaru, T.3    Erdjument-Bromage, H.4    Cooper, M.P.5    Ruas, J.L.6
  • 68
    • 33745198218 scopus 로고    scopus 로고
    • Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes
    • DOI 10.1074/jbc.M601295200
    • Musri MM, Corominola H, Casamitjana R, Gomis R, Parrizas M. Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes. J Biol Chem 2006; 281:17180-8. (Pubitemid 43909525)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.25 , pp. 17180-17188
    • Musri, M.M.1    Corominola, H.2    Casamitjana, R.3    Gomis, R.4    Parrizas, M.5
  • 69
    • 34547624303 scopus 로고    scopus 로고
    • Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen TS, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007; 448:553-60.
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1
  • 70
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006; 125:315-26.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5    Cuff, J.6
  • 71
    • 1942503942 scopus 로고    scopus 로고
    • The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    • DOI 10.1016/j.gde.2004.02.001, PII S0959437X0400022X
    • Cao R, Zhang Y. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev 2004; 14:155-64. (Pubitemid 38520143)
    • (2004) Current Opinion in Genetics and Development , vol.14 , Issue.2 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 72
    • 33846025127 scopus 로고    scopus 로고
    • Dynamic Regulation of Histone Lysine Methylation by Demethylases
    • DOI 10.1016/j.molcel.2006.12.010, PII S1097276506008689
    • Shi Y, Whetstine JR. Dynamic regulation of histone lysine methylation by demethylases. Mol Cell 2007; 25:1-14. (Pubitemid 46049067)
    • (2007) Molecular Cell , vol.25 , Issue.1 , pp. 1-14
    • Shi, Y.1    Whetstine, J.R.2
  • 73
    • 33646138230 scopus 로고    scopus 로고
    • JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
    • Yamane K, Toumazou C, Tsukada Y, Erdjument-Bromage H, Tempst P, Wong J, et al. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 2006; 125:483-95.
    • (2006) Cell , vol.125 , pp. 483-495
    • Yamane, K.1    Toumazou, C.2    Tsukada, Y.3    Erdjument-Bromage, H.4    Tempst, P.5    Wong, J.6
  • 74
    • 35948993829 scopus 로고    scopus 로고
    • Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis
    • DOI 10.1038/nature06236, PII NATURE06236
    • Okada Y, Scott G, Ray MK, Mishina Y, Zhang Y. Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. Nature 2007; 450:119-23. (Pubitemid 350070569)
    • (2007) Nature , vol.450 , Issue.7166 , pp. 119-123
    • Okada, Y.1    Scott, G.2    Ray, M.K.3    Mishina, Y.4    Zhang, Y.5
  • 75
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • Tateishi K, Okada Y, Kallin EM, Zhang Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 2009; 458:757-61.
    • (2009) Nature , vol.458 , pp. 757-761
    • Tateishi, K.1    Okada, Y.2    Kallin, E.M.3    Zhang, Y.4
  • 76
    • 68049095260 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
    • Inagaki T, Tachibana M, Magoori K, Kudo H, Tanaka T, Okamura M, et al. Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes Cells 2009; 14:991-1001.
    • (2009) Genes Cells , vol.14 , pp. 991-1001
    • Inagaki, T.1    Tachibana, M.2    Magoori, K.3    Kudo, H.4    Tanaka, T.5    Okamura, M.6
  • 77
    • 33646928066 scopus 로고    scopus 로고
    • Changes in gene expression foreshadow diet-induced obesity in genetically identical mice
    • DOI 10.1371/journal.pgen.0020081
    • Koza RA, Nikonova L, Hogan J, Rim J-S, Mendoza T, Faulk C, et al. Changes in gene expression foreshadow diet-induced obesity in genetically identical mice. PLoS Genet 2006; 2:81. (Pubitemid 43794325)
    • (2006) PLoS Genetics , vol.2 , Issue.5 , pp. 769-780
    • Koza, R.A.1    Nikonova, L.2    Hogan, J.3    Rim, J.-S.4    Mendoza, T.5    Faulk, C.6    Skaf, J.7    Kozak, L.P.8
  • 78
    • 0035650636 scopus 로고    scopus 로고
    • Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein C1
    • Jong MC, Voshol PJ, Muurling M, Dahlmans VE, Romijn JA, Pijl H, et al. Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein C1. Diabetes 2001; 50:2779-85. (Pubitemid 33733129)
    • (2001) Diabetes , vol.50 , Issue.12 , pp. 2779-2785
    • Jong, M.C.1    Voshol, P.J.2    Muurling, M.3    Dahlmans, V.E.H.4    Romijn, J.A.5    Pijl, H.6    Havekes, L.M.7
  • 79
    • 0030967868 scopus 로고    scopus 로고
    • Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene
    • Rossetti L, Stenbit AE, Chen W, Hu M, Barzilai N, Katz EB, et al. Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene. J Clin Invest 1997; 100:1831-9. (Pubitemid 27431342)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.7 , pp. 1831-1839
    • Rossetti, L.1    Stenbit, A.E.2    Chen, W.3    Hu, M.4    Barzilai, N.5    Katz, E.B.6    Charron, M.J.7
  • 80
    • 42349106044 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
    • DOI 10.1038/ng.120, PII NG120
    • Zeggini E, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008; 40:638-45. (Pubitemid 351601209)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 638-645
    • Zeggini, E.1    Scott, L.J.2    Saxena, R.3    Voight, B.F.4


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