-
1
-
-
9344233282
-
Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression
-
Aguilera C., Hoya-Arias R., Haegeman G., Espinosa L., Bigas A. Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:16537-16542.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 16537-16542
-
-
Aguilera, C.1
Hoya-Arias, R.2
Haegeman, G.3
Espinosa, L.4
Bigas, A.5
-
2
-
-
77955173972
-
Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia
-
Al Haj Zen A., Oikawa A., Bazan-Peregrino M., Meloni M., Emanueli C., Madeddu P. Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia. Circ. Res. 2010, 107(2):283-293.
-
(2010)
Circ. Res.
, vol.107
, Issue.2
, pp. 283-293
-
-
Al Haj Zen, A.1
Oikawa, A.2
Bazan-Peregrino, M.3
Meloni, M.4
Emanueli, C.5
Madeddu, P.6
-
3
-
-
84881549215
-
Notch signaling in the brain: in good and bad times
-
Alberi L., Hoey S.E., Brai E., Scotti A.L., Marathe S. Notch signaling in the brain: in good and bad times. Ageing Res. Rev. 2013, 12(3):801-814.
-
(2013)
Ageing Res. Rev.
, vol.12
, Issue.3
, pp. 801-814
-
-
Alberi, L.1
Hoey, S.E.2
Brai, E.3
Scotti, A.L.4
Marathe, S.5
-
4
-
-
2342496710
-
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
-
Amsen D., Blander J.M., Lee G.R., Tanigaki K., Honjo T., Flavell R.A. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 2004, 117(4):515-526.
-
(2004)
Cell
, vol.117
, Issue.4
, pp. 515-526
-
-
Amsen, D.1
Blander, J.M.2
Lee, G.R.3
Tanigaki, K.4
Honjo, T.5
Flavell, R.A.6
-
5
-
-
84949670848
-
Notch in t cell differentiation: all things considered
-
Amsen D., Helbig C., Backer R.A. Notch in t cell differentiation: all things considered. Trends Immunol. 2015, 36(12):802-814.
-
(2015)
Trends Immunol.
, vol.36
, Issue.12
, pp. 802-814
-
-
Amsen, D.1
Helbig, C.2
Backer, R.A.3
-
6
-
-
0345304893
-
Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts
-
Ando K., Kanazawa S., Tetsuka T., Ohta S., Jiang X., et al. Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts. Oncogene 2003, 22:7796-7803.
-
(2003)
Oncogene
, vol.22
, pp. 7796-7803
-
-
Ando, K.1
Kanazawa, S.2
Tetsuka, T.3
Ohta, S.4
Jiang, X.5
-
7
-
-
84920530980
-
The role of Notch pathway in cardiovascular diseases
-
Aquila G., Pannella M., Morelli M.B., Caliceti C., Fortini C., Rizzo P., Ferrari R. The role of Notch pathway in cardiovascular diseases. Glob. Cardiol. Sci. Pract. 2013, 2013(4):364-371.
-
(2013)
Glob. Cardiol. Sci. Pract.
, vol.2013
, Issue.4
, pp. 364-371
-
-
Aquila, G.1
Pannella, M.2
Morelli, M.B.3
Caliceti, C.4
Fortini, C.5
Rizzo, P.6
Ferrari, R.7
-
8
-
-
84923793318
-
Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain
-
Baik S.H., Fane M., Park J.H., Cheng Y.L., Yang-Wei Fann D., Yun U.J., Choi Y., Park J.S., Chai B.H., Park J.S., Back S.H., Jeong J.I., Jang Y.J., Bahn G., Lee J.Y., Li Y.I., Sobey C.G., Uchida T., Park J.H., Kim H.T., Tang S.C., Arumugam T.V., Jo D.G. Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain. Ann. Neurol. 2015, 77(3):504-516.
-
(2015)
Ann. Neurol.
, vol.77
, Issue.3
, pp. 504-516
-
-
Baik, S.H.1
Fane, M.2
Park, J.H.3
Cheng, Y.L.4
Yang-Wei Fann, D.5
Yun, U.J.6
Choi, Y.7
Park, J.S.8
Chai, B.H.9
Park, J.S.10
Back, S.H.11
Jeong, J.I.12
Jang, Y.J.13
Bahn, G.14
Lee, J.Y.15
Li, Y.I.16
Sobey, C.G.17
Uchida, T.18
Park, J.H.19
Kim, H.T.20
Tang, S.C.21
Arumugam, T.V.22
Jo, D.G.23
more..
-
9
-
-
27644490306
-
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression
-
Balint K., Xiao M., Pinnix C.C., Soma A., Veres I., Juhasz I., Brown E.J., Capobianco A.J., Herlyn M., Liu Z.J. Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. J. Clin. Invest. 2005, 115(11):3166-3176.
-
(2005)
J. Clin. Invest.
, vol.115
, Issue.11
, pp. 3166-3176
-
-
Balint, K.1
Xiao, M.2
Pinnix, C.C.3
Soma, A.4
Veres, I.5
Juhasz, I.6
Brown, E.J.7
Capobianco, A.J.8
Herlyn, M.9
Liu, Z.J.10
-
10
-
-
67651213832
-
TLR-4 polymorphisms and ageing: implications for the pathophysiology of age-related diseases
-
Balistreri C.R., Colonna-Romano G., Lio D., Candore G., Caruso C. TLR-4 polymorphisms and ageing: implications for the pathophysiology of age-related diseases. J. Clin. Immunol. 2009, 29(4):406-415.
-
(2009)
J. Clin. Immunol.
, vol.29
, Issue.4
, pp. 406-415
-
-
Balistreri, C.R.1
Colonna-Romano, G.2
Lio, D.3
Candore, G.4
Caruso, C.5
-
11
-
-
84860264551
-
Is the mean blood leukocyte telomere length a predictor for sporadic thoracic aortic aneurysm? Data from a preliminary study
-
Balistreri C.R., Pisano C., Merlo D., Fattouch K., Caruso M., Incalcaterra E., Colonna-Romano G., Candore G. Is the mean blood leukocyte telomere length a predictor for sporadic thoracic aortic aneurysm? Data from a preliminary study. Rejuvenation Res. 2012, 15(2):170-173.
-
(2012)
Rejuvenation Res.
, vol.15
, Issue.2
, pp. 170-173
-
-
Balistreri, C.R.1
Pisano, C.2
Merlo, D.3
Fattouch, K.4
Caruso, M.5
Incalcaterra, E.6
Colonna-Romano, G.7
Candore, G.8
-
12
-
-
84879120185
-
NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
-
Balistreri C.R., Candore G., Accardi G., Colonna-Romano G., Lio D. NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies. Immun. Ageing 2013, 10(1):24.
-
(2013)
Immun. Ageing
, vol.10
, Issue.1
, pp. 24
-
-
Balistreri, C.R.1
Candore, G.2
Accardi, G.3
Colonna-Romano, G.4
Lio, D.5
-
13
-
-
84924342441
-
Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?
-
Balistreri C.R., Pisano C., Martorana A., Triolo O.F., Lio D., Candore G., Ruvolo G. Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?. Age (Dordr) 2014, 36(5):9700.
-
(2014)
Age (Dordr)
, vol.36
, Issue.5
, pp. 9700
-
-
Balistreri, C.R.1
Pisano, C.2
Martorana, A.3
Triolo, O.F.4
Lio, D.5
Candore, G.6
Ruvolo, G.7
-
14
-
-
84947611086
-
Genetic contribution in sporadic thoracic aortic aneurysm? Emerging evidence of genetic variants related to TLR-4-mediated signaling pathway as risk determinants
-
Balistreri C.R. Genetic contribution in sporadic thoracic aortic aneurysm? Emerging evidence of genetic variants related to TLR-4-mediated signaling pathway as risk determinants. Vascul. Pharmacol. 2015, 74:1-10.
-
(2015)
Vascul. Pharmacol.
, vol.74
, pp. 1-10
-
-
Balistreri, C.R.1
-
15
-
-
0024542325
-
Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease
-
Barker D.J., Osmond C., Golding J., Kuh D., Wadsworth M.E. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989, 298(6673):564-567.
-
(1989)
BMJ
, vol.298
, Issue.6673
, pp. 564-567
-
-
Barker, D.J.1
Osmond, C.2
Golding, J.3
Kuh, D.4
Wadsworth, M.E.5
-
16
-
-
70449629775
-
Growth and chronic disease: findings in the Helsinki Birth Cohort
-
Barker D.J.P., Osmond C., Kajantie E., Eriksson J. Growth and chronic disease: findings in the Helsinki Birth Cohort. Ann. Hum. Biol. 2009, 36:445-458.
-
(2009)
Ann. Hum. Biol.
, vol.36
, pp. 445-458
-
-
Barker, D.J.P.1
Osmond, C.2
Kajantie, E.3
Eriksson, J.4
-
17
-
-
11844250659
-
The developmental origins of adult disease
-
588S95S
-
Barker D.J. The developmental origins of adult disease. J. Am. Coll. Nutr. 2004, 23:588S95S.
-
(2004)
J. Am. Coll. Nutr.
, vol.23
-
-
Barker, D.J.1
-
18
-
-
84859608557
-
Hematopoietic stem cells: to be or Notch to be
-
Bigas A., Espinosa L. Hematopoietic stem cells: to be or Notch to be. Blood 2012, 119(14):3226-3235.
-
(2012)
Blood
, vol.119
, Issue.14
, pp. 3226-3235
-
-
Bigas, A.1
Espinosa, L.2
-
19
-
-
0031899677
-
Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
-
Bigas A., Martin D.I., Milner L.A. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell. Biol. 1998, 18(4):2324-2333.
-
(1998)
Mol. Cell. Biol.
, vol.18
, Issue.4
, pp. 2324-2333
-
-
Bigas, A.1
Martin, D.I.2
Milner, L.A.3
-
20
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar A.G., Ouellette M., Frolkis M., Holt S.E., Chiu C.P., Morin G.B., Harley C.B., Shay J.W., Lichtsteiner S., Wright W.E. Extension of life-span by introduction of telomerase into normal human cells. Science 1998, 279(5349):349-352.
-
(1998)
Science
, vol.279
, Issue.5349
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
21
-
-
67650660754
-
The Notch signaling pathway: transcriptional regulation at Notch target genes
-
Borggrefe T., Oswald F. The Notch signaling pathway: transcriptional regulation at Notch target genes. Cell. Mol. Life Sci. 2009, 66(10):1631-1646.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, Issue.10
, pp. 1631-1646
-
-
Borggrefe, T.1
Oswald, F.2
-
22
-
-
84949293913
-
The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways
-
Borggrefe T., Lauth M., Zwijsen A., Huylebroeck D., Oswald F., Giaimo B.D. The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways. Biochim. Biophys. Acta 2016, 1863(2):303-313.
-
(2016)
Biochim. Biophys. Acta
, vol.1863
, Issue.2
, pp. 303-313
-
-
Borggrefe, T.1
Lauth, M.2
Zwijsen, A.3
Huylebroeck, D.4
Oswald, F.5
Giaimo, B.D.6
-
23
-
-
77951299101
-
Pim-1 kinase protects mitochondrial integrity in cardiomyocytes
-
Borillo G.A., Mason M., Quijada P., Völkers M., Cottage C., McGregor M., Din S., Fischer K., Gude N., Avitabile D., Barlow S., Alvarez R., Truffa S., Whittaker R., Glassy M.S., Gustafsson A.B., Miyamoto S., Glembotski C.C., Gottlieb R.A., Brown J.H., Sussman M.A. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circ. Res. 2010, 106(7):1265-1274.
-
(2010)
Circ. Res.
, vol.106
, Issue.7
, pp. 1265-1274
-
-
Borillo, G.A.1
Mason, M.2
Quijada, P.3
Völkers, M.4
Cottage, C.5
McGregor, M.6
Din, S.7
Fischer, K.8
Gude, N.9
Avitabile, D.10
Barlow, S.11
Alvarez, R.12
Truffa, S.13
Whittaker, R.14
Glassy, M.S.15
Gustafsson, A.B.16
Miyamoto, S.17
Glembotski, C.C.18
Gottlieb, R.A.19
Brown, J.H.20
Sussman, M.A.21
more..
-
24
-
-
70450280750
-
TERT over-expression affects the growth of myocardial tissue derived from mouse embryonic stem cells
-
Brandt S. TERT over-expression affects the growth of myocardial tissue derived from mouse embryonic stem cells. Differentiation 2010, 79(1):1-8.
-
(2010)
Differentiation
, vol.79
, Issue.1
, pp. 1-8
-
-
Brandt, S.1
-
25
-
-
33747623018
-
Notch signalling: a simple pathway becomes complex
-
Bray S.J. Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 2006, 7(9):678-689.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, Issue.9
, pp. 678-689
-
-
Bray, S.J.1
-
26
-
-
84969316154
-
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis
-
Briot A., Civelek M., Seki A., Hoi K., Mack J.J., Lee S.D., Kim J., Hong C., Yu J., Fishbein G.A., Vakili L., Fogelman A.M., Fishbein M.C., Lusis A.J., Tontonoz P., Navab M., Berliner J.A., Iruela-Arispe M.L. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. J. Exp. Med. 2015, 212(12):2147-2163.
-
(2015)
J. Exp. Med.
, vol.212
, Issue.12
, pp. 2147-2163
-
-
Briot, A.1
Civelek, M.2
Seki, A.3
Hoi, K.4
Mack, J.J.5
Lee, S.D.6
Kim, J.7
Hong, C.8
Yu, J.9
Fishbein, G.A.10
Vakili, L.11
Fogelman, A.M.12
Fishbein, M.C.13
Lusis, A.J.14
Tontonoz, P.15
Navab, M.16
Berliner, J.A.17
Iruela-Arispe, M.L.18
-
27
-
-
0034681260
-
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
-
Brown M.S., Ye J., Rawson R.B., Goldstein J.L. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 2000, 100(4):391-398.
-
(2000)
Cell
, vol.100
, Issue.4
, pp. 391-398
-
-
Brown, M.S.1
Ye, J.2
Rawson, R.B.3
Goldstein, J.L.4
-
29
-
-
80855128461
-
Cellular senescence: a link between cancer and age-related degenerative disease
-
Campisi J., Andersen J.K., Kapahi P., Melov S. Cellular senescence: a link between cancer and age-related degenerative disease. Semin. Cancer Biol. 2011, 21:354-359.
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 354-359
-
-
Campisi, J.1
Andersen, J.K.2
Kapahi, P.3
Melov, S.4
-
30
-
-
0037195730
-
Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation
-
Campos A.H., Wang W., Pollman M.J., Gibbons G.H. Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation. Circ. Res. 2002, 91(11):999-1006.
-
(2002)
Circ. Res.
, vol.91
, Issue.11
, pp. 999-1006
-
-
Campos, A.H.1
Wang, W.2
Pollman, M.J.3
Gibbons, G.H.4
-
31
-
-
34547513872
-
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2
-
Candi E., Rufini A., Terrinoni A., Giamboi-Miraglia A., Lena A.M., Mantovani R., Knight R., Melino G. DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(29):11999-12004.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, Issue.29
, pp. 11999-12004
-
-
Candi, E.1
Rufini, A.2
Terrinoni, A.3
Giamboi-Miraglia, A.4
Lena, A.M.5
Mantovani, R.6
Knight, R.7
Melino, G.8
-
32
-
-
79955637705
-
Soluble Jagged-1 inhibits neointima formation by attenuating Notch-Herp2 signaling
-
Caolo V., Schulten H.M., Zhuang Z.W., Murakami M., Wagenaar A., Verbruggen S., Molin D.G., Post M.J. Soluble Jagged-1 inhibits neointima formation by attenuating Notch-Herp2 signaling. Arterioscler. Thromb. Vasc. Biol. 2011, 31(5):1059-1065.
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, Issue.5
, pp. 1059-1065
-
-
Caolo, V.1
Schulten, H.M.2
Zhuang, Z.W.3
Murakami, M.4
Wagenaar, A.5
Verbruggen, S.6
Molin, D.G.7
Post, M.J.8
-
33
-
-
43049168216
-
Aging of signal transduction pathways, and pathology
-
Carlson M.E., Silva H.S., Conboy I.M. Aging of signal transduction pathways, and pathology. Exp. Cell Res. 2008, 314(9):1951-1961.
-
(2008)
Exp. Cell Res.
, vol.314
, Issue.9
, pp. 1951-1961
-
-
Carlson, M.E.1
Silva, H.S.2
Conboy, I.M.3
-
34
-
-
47949097215
-
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
-
Carlson M.E., Hsu M., Conboy I.M. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 2008, 454(7203):528-532.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 528-532
-
-
Carlson, M.E.1
Hsu, M.2
Conboy, I.M.3
-
35
-
-
77951664071
-
Molecular aging and rejuvenation of human muscle stem cells
-
Carlson M.E., Suetta C., Conboy M.J., Aagaard P., Mackey A., Kjaer M., Conboy I. Molecular aging and rejuvenation of human muscle stem cells. EMBO Mol. Med. 2009, 1(8-9):381-391.
-
(2009)
EMBO Mol. Med.
, vol.1
, Issue.8-9
, pp. 381-391
-
-
Carlson, M.E.1
Suetta, C.2
Conboy, M.J.3
Aagaard, P.4
Mackey, A.5
Kjaer, M.6
Conboy, I.7
-
37
-
-
84930786234
-
Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model
-
Cheng J., Koenig S.N., Kuivaniemi H.S., Garg V., Hans C.P. Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model. J. Am. Heart Assoc. 2014, 3(6):e001064. 10.1161/JAHA.114.001064.
-
(2014)
J. Am. Heart Assoc.
, vol.3
, Issue.6
-
-
Cheng, J.1
Koenig, S.N.2
Kuivaniemi, H.S.3
Garg, V.4
Hans, C.P.5
-
38
-
-
84887143993
-
Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke
-
Cheng Y.L., Park J.S., Manzanero S., Choi Y., Baik S.H., Okun E., Gelderblom M., Fann D.Y., Magnus T., Launikonis B.S., Mattson M.P., Sobey C.G., Jo D.G., Arumugam T.V. Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke. Neurobiol. Dis. 2014, 62:286-295.
-
(2014)
Neurobiol. Dis.
, vol.62
, pp. 286-295
-
-
Cheng, Y.L.1
Park, J.S.2
Manzanero, S.3
Choi, Y.4
Baik, S.H.5
Okun, E.6
Gelderblom, M.7
Fann, D.Y.8
Magnus, T.9
Launikonis, B.S.10
Mattson, M.P.11
Sobey, C.G.12
Jo, D.G.13
Arumugam, T.V.14
-
39
-
-
84866747427
-
Mesenchymal stem cells conditioned with glucose depletion augments their ability to repair-infarcted myocardium
-
Choudhery M.S., Khan M., Mahmood R., Mohsin S., Akhtar S., Ali F., Khan S.N., Riazuddin S. Mesenchymal stem cells conditioned with glucose depletion augments their ability to repair-infarcted myocardium. J. Cell Mol. Med. 2012, 16(10):2518-2529.
-
(2012)
J. Cell Mol. Med.
, vol.16
, Issue.10
, pp. 2518-2529
-
-
Choudhery, M.S.1
Khan, M.2
Mahmood, R.3
Mohsin, S.4
Akhtar, S.5
Ali, F.6
Khan, S.N.7
Riazuddin, S.8
-
40
-
-
57949087452
-
Molecular inflammation: underpinnings of aging and age-related diseases
-
Chung H.Y., Cesari M., Anton S., Marzetti E., Giovannini S., Seo A.Y., Carter C., Yu B.P., Leeuwenburgh C. Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res. Rev. 2009, 8(1):18-30.
-
(2009)
Ageing Res. Rev.
, vol.8
, Issue.1
, pp. 18-30
-
-
Chung, H.Y.1
Cesari, M.2
Anton, S.3
Marzetti, E.4
Giovannini, S.5
Seo, A.Y.6
Carter, C.7
Yu, B.P.8
Leeuwenburgh, C.9
-
41
-
-
35649000861
-
Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk
-
Clément N., Gueguen M., Glorian M., Blaise R., Andréani M., Brou C., Bausero P., Limon I. Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk. J. Cell Sci. 2007, 120(Pt 19):3352-3361.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 3352-3361
-
-
Clément, N.1
Gueguen, M.2
Glorian, M.3
Blaise, R.4
Andréani, M.5
Brou, C.6
Bausero, P.7
Limon, I.8
-
42
-
-
0344827208
-
Notch-mediated restoration of regenerative potential to aged muscle
-
Conboy I.M., Conboy M.J., Smythe G.M., Rando T.A. Notch-mediated restoration of regenerative potential to aged muscle. Science 2003, 302(5650):1575-1577.
-
(2003)
Science
, vol.302
, Issue.5650
, pp. 1575-1577
-
-
Conboy, I.M.1
Conboy, M.J.2
Smythe, G.M.3
Rando, T.A.4
-
43
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy I.M., Conboy M.J., Wagers A.J., Girma E.R., Weissman I.L., Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005, 433(7027):760-764.
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weissman, I.L.5
Rando, T.A.6
-
44
-
-
77149162007
-
The role of notch signaling in the development of a normal B-cell repertoire
-
Cruickshank M.N., Ulgiati D. The role of notch signaling in the development of a normal B-cell repertoire. Immunol. Cell Biol. 2010, 88(2):117-124.
-
(2010)
Immunol. Cell Biol.
, vol.88
, Issue.2
, pp. 117-124
-
-
Cruickshank, M.N.1
Ulgiati, D.2
-
45
-
-
50849100996
-
The many facets of Notch ligands
-
D'Souza B., Miyamoto A., Weinmaster G. The many facets of Notch ligands. Oncogene 2008, 27(38):5148-5167.
-
(2008)
Oncogene
, vol.27
, Issue.38
, pp. 5148-5167
-
-
D'Souza, B.1
Miyamoto, A.2
Weinmaster, G.3
-
47
-
-
27144518462
-
Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells
-
Delaney C., Varnum-Finney B., Aoyama K., Brashem-Stein C., Bernstein I.D. Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells. Blood 2005, 106(8):2693-2699.
-
(2005)
Blood
, vol.106
, Issue.8
, pp. 2693-2699
-
-
Delaney, C.1
Varnum-Finney, B.2
Aoyama, K.3
Brashem-Stein, C.4
Bernstein, I.D.5
-
48
-
-
33646008578
-
Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors
-
de Pooter R.F., Schmitt T.M., de la Pompa J.L., Fujiwara Y., Orkin S.H., Zúñiga-Pflücker J.C. Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors. J. Immunol. 2006, 176(9):5267-5275.
-
(2006)
J. Immunol.
, vol.176
, Issue.9
, pp. 5267-5275
-
-
de Pooter, R.F.1
Schmitt, T.M.2
de la Pompa, J.L.3
Fujiwara, Y.4
Orkin, S.H.5
Zúñiga-Pflücker, J.C.6
-
49
-
-
8644219667
-
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
-
Domenga V., Fardoux P., Lacombe P., Monet M., Maciazek J., Krebs L.T., Klonjkowski B., Berrou E., Mericskay M., Li Z., Tournier-Lasserve E., Gridley T., Joutel A. Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. Genes Dev. 2004, 18(22):2730-2735.
-
(2004)
Genes Dev.
, vol.18
, Issue.22
, pp. 2730-2735
-
-
Domenga, V.1
Fardoux, P.2
Lacombe, P.3
Monet, M.4
Maciazek, J.5
Krebs, L.T.6
Klonjkowski, B.7
Berrou, E.8
Mericskay, M.9
Li, Z.10
Tournier-Lasserve, E.11
Gridley, T.12
Joutel, A.13
-
50
-
-
84872380883
-
Population aging, the dependency burden, and challenges facing preventive medicine
-
Edwards R.D. Population aging, the dependency burden, and challenges facing preventive medicine. Prev. Med. 2012, 55(6):533-534.
-
(2012)
Prev. Med.
, vol.55
, Issue.6
, pp. 533-534
-
-
Edwards, R.D.1
-
51
-
-
73649095167
-
KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia
-
Emuss V., Lagos D., Pizzey A., Gratrix F., Henderson S.R., Boshoff C. KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia. PLoS Pathog. 2009, 5(10):e1000616.
-
(2009)
PLoS Pathog.
, vol.5
, Issue.10
-
-
Emuss, V.1
Lagos, D.2
Pizzey, A.3
Gratrix, F.4
Henderson, S.R.5
Boshoff, C.6
-
52
-
-
77956511912
-
The Notch/Hes1 pathway sustains NF-kappaB activation through CYLD repression in T cell leukemia
-
Espinosa L., Cathelin S., D'Altri T., Trimarchi T., Statnikov A., et al. The Notch/Hes1 pathway sustains NF-kappaB activation through CYLD repression in T cell leukemia. Cancer Cell 2010, 18:268-281.
-
(2010)
Cancer Cell
, vol.18
, pp. 268-281
-
-
Espinosa, L.1
Cathelin, S.2
D'Altri, T.3
Trimarchi, T.4
Statnikov, A.5
-
53
-
-
34748851341
-
Cell and molecular biology of Notch
-
Fiúza U.M., Arias A.M. Cell and molecular biology of Notch. J. Endocrinol. 2007, 194(3):459-474.
-
(2007)
J. Endocrinol.
, vol.194
, Issue.3
, pp. 459-474
-
-
Fiúza, U.M.1
Arias, A.M.2
-
54
-
-
73949116951
-
Notch-Off: a perspective on the termination of Notch signalling
-
Fior R., Henrique D. Notch-Off: a perspective on the termination of Notch signalling. Int. J. Dev. Biol. 2009, 53(8-10):1379-1384.
-
(2009)
Int. J. Dev. Biol.
, vol.53
, Issue.8-10
, pp. 1379-1384
-
-
Fior, R.1
Henrique, D.2
-
55
-
-
1942498907
-
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
-
Fischer A., Schumacher N., Maier M., Sendtner M., Gessler M. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004, 18(8):901-911.
-
(2004)
Genes Dev.
, vol.18
, Issue.8
, pp. 901-911
-
-
Fischer, A.1
Schumacher, N.2
Maier, M.3
Sendtner, M.4
Gessler, M.5
-
56
-
-
73449130151
-
Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase
-
Fischer K.M., Cottage C.T., Wu W., Din S., Gude N.A., Avitabile D., Quijada P., Collins B.L., Fransioli J., Sussman M.A. Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase. Circulation 2009, 120(21):2077-2087.
-
(2009)
Circulation
, vol.120
, Issue.21
, pp. 2077-2087
-
-
Fischer, K.M.1
Cottage, C.T.2
Wu, W.3
Din, S.4
Gude, N.A.5
Avitabile, D.6
Quijada, P.7
Collins, B.L.8
Fransioli, J.9
Sussman, M.A.10
-
57
-
-
78149475633
-
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1
-
Foldi J., Chung A.Y., Xu H., Zhu J., Outtz H.H., Kitajewski J., Li Y., Hu X., Ivashkiv L.B. Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. J. Immunol. 2010, 185(9):5023-5031.
-
(2010)
J. Immunol.
, vol.185
, Issue.9
, pp. 5023-5031
-
-
Foldi, J.1
Chung, A.Y.2
Xu, H.3
Zhu, J.4
Outtz, H.H.5
Kitajewski, J.6
Li, Y.7
Hu, X.8
Ivashkiv, L.B.9
-
58
-
-
84961125990
-
RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes
-
Foldi J., Shang Y., Zhao B., Ivashkiv L.B., Hu X. RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes. Protein Cell 2016, 7(3):201-209.
-
(2016)
Protein Cell
, vol.7
, Issue.3
, pp. 201-209
-
-
Foldi, J.1
Shang, Y.2
Zhao, B.3
Ivashkiv, L.B.4
Hu, X.5
-
59
-
-
0033911488
-
Inflamm-aging: an evolutionary perspective on immunosenescence
-
Franceschi C., Bonafè M., Valensin S., Olivieri F., De Luca M., Ottaviani E., De Benedictis G. Inflamm-aging: an evolutionary perspective on immunosenescence. Ann. N. Y. Acad. Sci. 2000, 908:244-254.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafè, M.2
Valensin, S.3
Olivieri, F.4
De Luca, M.5
Ottaviani, E.6
De Benedictis, G.7
-
60
-
-
84863605556
-
Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders
-
Fukuda D., Aikawa E., Swirski F.K., Novobrantseva T.I., Kotelianski V., Gorgun C.Z., Chudnovskiy A., Yamazaki H., Croce K., Weissleder R., Aster J.C., Hotamisligil G.S., Yagita H., Aikawa M. Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Proc. Natl. Acad. Sci. U. S. A. 2012, 109(27):E1868-77.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, Issue.27
, pp. E1868-E1877
-
-
Fukuda, D.1
Aikawa, E.2
Swirski, F.K.3
Novobrantseva, T.I.4
Kotelianski, V.5
Gorgun, C.Z.6
Chudnovskiy, A.7
Yamazaki, H.8
Croce, K.9
Weissleder, R.10
Aster, J.C.11
Hotamisligil, G.S.12
Yagita, H.13
Aikawa, M.14
-
61
-
-
34250313956
-
Delta-like 4 induces notch signaling in macrophages: implications for inflammation
-
Fung E., Tang S.M., Canner J.P., Morishige K., Arboleda-Velasquez J.F., Cardoso A.A., Carlesso N., Aster J.C., Aikawa M. Delta-like 4 induces notch signaling in macrophages: implications for inflammation. Circulation 2007, 115(23):2948-2956.
-
(2007)
Circulation
, vol.115
, Issue.23
, pp. 2948-2956
-
-
Fung, E.1
Tang, S.M.2
Canner, J.P.3
Morishige, K.4
Arboleda-Velasquez, J.F.5
Cardoso, A.A.6
Carlesso, N.7
Aster, J.C.8
Aikawa, M.9
-
62
-
-
8644290828
-
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development
-
Gale N.W., Dominguez M.G., Noguera I., Pan L., Hughes V., Valenzuela D.M., Murphy A.J., Adams N.C., Lin H.C., Holash J., Thurston G., Yancopoulos G.D. Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(45):15949-15954.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, Issue.45
, pp. 15949-15954
-
-
Gale, N.W.1
Dominguez, M.G.2
Noguera, I.3
Pan, L.4
Hughes, V.5
Valenzuela, D.M.6
Murphy, A.J.7
Adams, N.C.8
Lin, H.C.9
Holash, J.10
Thurston, G.11
Yancopoulos, G.D.12
-
63
-
-
24644467759
-
Mutations in NOTCH1 cause aortic valve disease
-
Garg V., Muth A.N., Ransom J.F., Schluterman M.K., Barnes R., King I.N., Grossfeld P.D., Srivastava D. Mutations in NOTCH1 cause aortic valve disease. Nature 2005, 437(7056):270-274.
-
(2005)
Nature
, vol.437
, Issue.7056
, pp. 270-274
-
-
Garg, V.1
Muth, A.N.2
Ransom, J.F.3
Schluterman, M.K.4
Barnes, R.5
King, I.N.6
Grossfeld, P.D.7
Srivastava, D.8
-
64
-
-
84911092143
-
Macrophage heterogeneity in tissues: phenotypic diversity and functions
-
Gordon S., Plüddemann A., Martinez Estrada F. Macrophage heterogeneity in tissues: phenotypic diversity and functions. Immunol. Rev. 2014, 262(1):36-55.
-
(2014)
Immunol. Rev.
, vol.262
, Issue.1
, pp. 36-55
-
-
Gordon, S.1
Plüddemann, A.2
Martinez Estrada, F.3
-
65
-
-
37749036806
-
Entropy explains aging, genetic determinism explains longevity, and undefined terminology explains misunderstanding both
-
Hayflick L. Entropy explains aging, genetic determinism explains longevity, and undefined terminology explains misunderstanding both. PLoS Genet. 2007, 3:e220.
-
(2007)
PLoS Genet.
, vol.3
, pp. e220
-
-
Hayflick, L.1
-
66
-
-
79952444246
-
Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association
-
Heidenreich, P.A., Trogdon, J.G., Khavjou, O.A., Butler, J., Dracup, K., Ezekowitz, M.D., Finkelstein, E.A., Hong, Y., Johnston, S.C., Khera, A., Lloyd-Jones, D.M., Nelson, S.A., Nichol, G., Orenstein, D., Wilson, P.W., Woo, Y.J., 2011. American Heart Association Advocacy Coordinating Committee; Stroke Council; Council on Cardiovascular Radiology and Intervention; Council on Clinical Cardiology; Council on Epidemiology and Prevention; Council on Arteriosclerosis; Thrombosis and Vascular Biology; Councilon Cardiopulmonary; Critical Care; Perioperative and Resuscitation; Council onCardiovascular Nursing; Council on the Kidney in Cardiovascular Disease; Council on Cardiovascular Surgery and Anesthesia, and Interdisciplinary Council onQuality of Care and Outcomes Research. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation. 123 (8), 933-44.
-
(2011)
Circulation
, vol.123
, Issue.8
, pp. 933-944
-
-
Heidenreich, P.A.1
Trogdon, J.G.2
Khavjou, O.A.3
Butler, J.4
Dracup, K.5
Ezekowitz, M.D.6
Finkelstein, E.A.7
Hong, Y.8
Johnston, S.C.9
Khera, A.10
Lloyd-Jones, D.M.11
Nelson, S.A.12
Nichol, G.13
Orenstein, D.14
Wilson, P.W.15
Woo, Y.J.16
-
67
-
-
55349128861
-
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways
-
Hu X., Chung A.Y., Wu I., Foldi J., Chen J., Ji J.D., Tateya T., Kang Y.J., Han J., Gessler M., Kageyama R., Ivashkiv L.B. Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity 2008, 29(5):691-703.
-
(2008)
Immunity
, vol.29
, Issue.5
, pp. 691-703
-
-
Hu, X.1
Chung, A.Y.2
Wu, I.3
Foldi, J.4
Chen, J.5
Ji, J.D.6
Tateya, T.7
Kang, Y.J.8
Han, J.9
Gessler, M.10
Kageyama, R.11
Ivashkiv, L.B.12
-
69
-
-
84855432882
-
The use of polyethylenimine-DNA to topically deliver hTERT to promote hair growth
-
Jan H.M., Wei M.F., Peng C.L., Lin S.J., Lai P.S., Shieh M.J. The use of polyethylenimine-DNA to topically deliver hTERT to promote hair growth. Gene Ther. 2012, 19(1):86-93.
-
(2012)
Gene Ther.
, vol.19
, Issue.1
, pp. 86-93
-
-
Jan, H.M.1
Wei, M.F.2
Peng, C.L.3
Lin, S.J.4
Lai, P.S.5
Shieh, M.J.6
-
70
-
-
76249101454
-
Cutting edge: plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis
-
Kassner N., Krueger M., Yagita H., Dzionek A., Hutloff A., Kroczek R., Scheffold A., Rutz S. Cutting edge: plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis. J. Immunol. 2010, 184(2):550-554.
-
(2010)
J. Immunol.
, vol.184
, Issue.2
, pp. 550-554
-
-
Kassner, N.1
Krueger, M.2
Yagita, H.3
Dzionek, A.4
Hutloff, A.5
Kroczek, R.6
Scheffold, A.7
Rutz, S.8
-
71
-
-
5444242184
-
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
-
Krebs L.T., Shutter J.R., Tanigaki K., Honjo T., Stark K.L., Gridley T. Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev. 2004, 18(20):2469-2473.
-
(2004)
Genes Dev.
, vol.18
, Issue.20
, pp. 2469-2473
-
-
Krebs, L.T.1
Shutter, J.R.2
Tanigaki, K.3
Honjo, T.4
Stark, K.L.5
Gridley, T.6
-
72
-
-
78349257844
-
The essence of senescence
-
Kuilman T., Michaloglou C., Mooi W.J., Peeper D.S. The essence of senescence. Genes Dev. 2010, 24:2463-2479.
-
(2010)
Genes Dev.
, vol.24
, pp. 2463-2479
-
-
Kuilman, T.1
Michaloglou, C.2
Mooi, W.J.3
Peeper, D.S.4
-
73
-
-
0035760308
-
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression
-
Kumano K., Chiba S., Shimizu K., Yamagata T., Hosoya N., Saito T., Takahashi T., Hamada Y., Hirai H. Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression. Blood 2001, 98(12):3283-3289.
-
(2001)
Blood
, vol.98
, Issue.12
, pp. 3283-3289
-
-
Kumano, K.1
Chiba, S.2
Shimizu, K.3
Yamagata, T.4
Hosoya, N.5
Saito, T.6
Takahashi, T.7
Hamada, Y.8
Hirai, H.9
-
74
-
-
84875412113
-
Functional macrophage heterogeneity in a mouse model of autoimmune central nervous system pathology
-
London A., Benhar I., Mattapallil M.J., Mack M., Caspi R.R., Schwartz M. Functional macrophage heterogeneity in a mouse model of autoimmune central nervous system pathology. J. Immunol. 2013, 190(7):3570-3578.
-
(2013)
J. Immunol.
, vol.190
, Issue.7
, pp. 3570-3578
-
-
London, A.1
Benhar, I.2
Mattapallil, M.J.3
Mack, M.4
Caspi, R.R.5
Schwartz, M.6
-
75
-
-
1642523576
-
Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways
-
MacKenzie F., Duriez P., Wong F., Noseda M., Karsan A. Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways. J. Biol. Chem. 2004, 279(12):11657-11663.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.12
, pp. 11657-11663
-
-
MacKenzie, F.1
Duriez, P.2
Wong, F.3
Noseda, M.4
Karsan, A.5
-
76
-
-
38349068944
-
Myocardin a enhances an enhances telomerase activities in adipose tissue mesenchymal cells and embryonic stem cells undergoing cardiovascular myogenic differentiation
-
Madonna R., Willerson J.T., Geng Y.J. Myocardin a enhances an enhances telomerase activities in adipose tissue mesenchymal cells and embryonic stem cells undergoing cardiovascular myogenic differentiation. Stem Cells 2008, 26(1):202-211.
-
(2008)
Stem Cells
, vol.26
, Issue.1
, pp. 202-211
-
-
Madonna, R.1
Willerson, J.T.2
Geng, Y.J.3
-
77
-
-
84883763154
-
Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells
-
Madonna R., Wu D., Wassler M., De Caterina R., Willerson J.T., Geng Y.J. Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells. Int. J. Cardiol. 2013, 167(6):2912-2921.
-
(2013)
Int. J. Cardiol.
, vol.167
, Issue.6
, pp. 2912-2921
-
-
Madonna, R.1
Wu, D.2
Wassler, M.3
De Caterina, R.4
Willerson, J.T.5
Geng, Y.J.6
-
78
-
-
84940902140
-
Stem cell aging and age-related cardiovascular disease: perspectives of treatment by ex-vivo stem cell rejuvenation
-
Madonna R., Engel F.B., Davidson S.M., Ferdinandy P., Gorbe A., Sluijter J.P., Van Laake L.W. Stem cell aging and age-related cardiovascular disease: perspectives of treatment by ex-vivo stem cell rejuvenation. Curr. Drug Targets 2015, 16(8):780-785.
-
(2015)
Curr. Drug Targets
, vol.16
, Issue.8
, pp. 780-785
-
-
Madonna, R.1
Engel, F.B.2
Davidson, S.M.3
Ferdinandy, P.4
Gorbe, A.5
Sluijter, J.P.6
Van Laake, L.W.7
-
79
-
-
85006201188
-
Cellular and molecular basis of the imbalance between vascular damage and repair in aging and age-related diseases: as biomarkers and targets for new treatments
-
[Epub ahead of print]
-
Madonna R., Balistreri C.R., Novo G. Cellular and molecular basis of the imbalance between vascular damage and repair in aging and age-related diseases: as biomarkers and targets for new treatments. Mech. Ageing Dev. 2016, pii: S0047-6374(16)30026-4. 10.1016/j.mad.2016.03.005 [Epub ahead of print].
-
(2016)
Mech. Ageing Dev.
-
-
Madonna, R.1
Balistreri, C.R.2
Novo, G.3
-
80
-
-
84976511014
-
Position Paper of the ESC Working Group Cellular Biology of the Heart: Cell-Based Therapies for Myocardial Repair and Regeneration in Ischemic Heart Disease and Heart Failure
-
(in press).
-
Madonna R. Linda, W. Van Laake, Sean M. Davidson, Felix B. Engel, Derek J. Hausenloy, Sandrine Lecour, Jonathan Leor, Cinzia Perrino, Rainer Schulz, Kirsti Ytrehus, Ulf Landmesser, Christine L. Mummery, Stefan Janssens, James Willerson, Thomas Eschenhagen, Peter Ferdinandy, Joost P.G. Sluijter, Position Paper of the ESC Working Group Cellular Biology of the Heart: Cell-Based Therapies for Myocardial Repair and Regeneration in Ischemic Heart Disease and Heart Failure. Eur. Heart J. 2016 (in press).
-
(2016)
Eur. Heart J.
-
-
Linda, M.R.1
Van Laake, W.2
Davidson, S.M.3
Engel, F.B.4
Hausenloy, D.J.5
Lecour, S.6
Leor, J.7
Perrino, C.8
Schulz, R.9
Ytrehus, K.10
Landmesser, U.11
Mummery, C.L.12
Janssens, S.13
Willerson, J.14
Eschenhagen, T.15
Ferdinandy, P.16
Sluijter, J.P.G.17
-
81
-
-
84055217307
-
Crosstalk between the canonical NF-kappaB and Notch signaling pathways inhibits Ppargamma expression and promotes pancreatic cancer progression in mice
-
Maniati, Bossard M., Cook N., Candido J.B., Emami-Shahri N., et al. Crosstalk between the canonical NF-kappaB and Notch signaling pathways inhibits Ppargamma expression and promotes pancreatic cancer progression in mice. J. Clin. Invest. 2011, 121:4685-4699.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4685-4699
-
-
Maniati1
Bossard, M.2
Cook, N.3
Candido, J.B.4
Emami-Shahri, N.5
-
82
-
-
0029850324
-
Inhibition of granulocytic differentiation by mNotch1
-
Milner L.A., Bigas A., Kopan R., Brashem-Stein C., Bernstein I.D., Martin D.I. Inhibition of granulocytic differentiation by mNotch1. Proc. Natl. Acad. Sci. U. S. A. 1996, 93(23):13014-13019.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, Issue.23
, pp. 13014-13019
-
-
Milner, L.A.1
Bigas, A.2
Kopan, R.3
Brashem-Stein, C.4
Bernstein, I.D.5
Martin, D.I.6
-
83
-
-
84887181533
-
Rejuvenation of human cardiac progenitor cells with Pim-1 kinase
-
Mohsin S., Khan M., Nguyen J., Alkatib M., Siddiqi S., Hariharan N., Wallach K., Monsanto M., Gude N., Dembitsky W., Sussman M.A. Rejuvenation of human cardiac progenitor cells with Pim-1 kinase. Circ. Res. 2013, 113(10):1169-1179.
-
(2013)
Circ. Res.
, vol.113
, Issue.10
, pp. 1169-1179
-
-
Mohsin, S.1
Khan, M.2
Nguyen, J.3
Alkatib, M.4
Siddiqi, S.5
Hariharan, N.6
Wallach, K.7
Monsanto, M.8
Gude, N.9
Dembitsky, W.10
Sussman, M.A.11
-
84
-
-
84866735552
-
Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair
-
Mohsin S., Khan M., Toko H., Bailey B., Cottage C.T., Wallach K., Nag D., Lee A., Siddiqi S., Lan F., Fischer K.M., Gude N., Quijada P., Avitabile D., Truffa S., Collins B., Dembitsky W., Wu J.C., Sussman M.A. Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. J. Am. Coll. Cardiol. 2012, 60(14):1278-1287.
-
(2012)
J. Am. Coll. Cardiol.
, vol.60
, Issue.14
, pp. 1278-1287
-
-
Mohsin, S.1
Khan, M.2
Toko, H.3
Bailey, B.4
Cottage, C.T.5
Wallach, K.6
Nag, D.7
Lee, A.8
Siddiqi, S.9
Lan, F.10
Fischer, K.M.11
Gude, N.12
Quijada, P.13
Avitabile, D.14
Truffa, S.15
Collins, B.16
Dembitsky, W.17
Wu, J.C.18
Sussman, M.A.19
-
85
-
-
73649105844
-
Drosophila Hey is a target of Notch in asymmetric divisions during embryonic and larval neurogenesis
-
Monastirioti M., Giagtzoglou N., Koumbanakis K.A., Zacharioudaki E., Deligiannaki M., Wech I., Almeida M., Preiss A., Bray S., Delidakis C. Drosophila Hey is a target of Notch in asymmetric divisions during embryonic and larval neurogenesis. Development 2010, 137(2):191-201.
-
(2010)
Development
, vol.137
, Issue.2
, pp. 191-201
-
-
Monastirioti, M.1
Giagtzoglou, N.2
Koumbanakis, K.A.3
Zacharioudaki, E.4
Deligiannaki, M.5
Wech, I.6
Almeida, M.7
Preiss, A.8
Bray, S.9
Delidakis, C.10
-
86
-
-
33645976866
-
Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity
-
Monsalve E., Perez M.A., Rubio A., Ruiz-Hidalgo M.J., Baladron V., et al. Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity. J. Immunol. 2006, 176:5362-5373.
-
(2006)
J. Immunol.
, vol.176
, pp. 5362-5373
-
-
Monsalve, E.1
Perez, M.A.2
Rubio, A.3
Ruiz-Hidalgo, M.J.4
Baladron, V.5
-
87
-
-
70349249979
-
Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity
-
Monsalve E., Ruiz-Garcia A., Baladron V., Ruiz-Hidalgo M.J., Sanchez-Solana B., et al. Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity. Eur. J. Immunol. 2009, 39:2556-2570.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2556-2570
-
-
Monsalve, E.1
Ruiz-Garcia, A.2
Baladron, V.3
Ruiz-Hidalgo, M.J.4
Sanchez-Solana, B.5
-
88
-
-
0034671686
-
Notch signaling: from the outside in
-
Mumm J.S., Kopan R. Notch signaling: from the outside in. Dev. Biol. 2000, 228(2):151-165.
-
(2000)
Dev. Biol.
, vol.228
, Issue.2
, pp. 151-165
-
-
Mumm, J.S.1
Kopan, R.2
-
89
-
-
84906653542
-
The Notch pathway controls fibrotic and regenerative repair in the adult heart
-
Nemir M., Metrich M., Plaisance I., Lepore M., Cruchet S., Berthonneche C., Sarre A., Radtke F., Pedrazzini T. The Notch pathway controls fibrotic and regenerative repair in the adult heart. Eur. Heart J. 2014, 35(32):2174-2185.
-
(2014)
Eur. Heart J.
, vol.35
, Issue.32
, pp. 2174-2185
-
-
Nemir, M.1
Metrich, M.2
Plaisance, I.3
Lepore, M.4
Cruchet, S.5
Berthonneche, C.6
Sarre, A.7
Radtke, F.8
Pedrazzini, T.9
-
90
-
-
45149102678
-
Notch signaling in cardiac development
-
Niessen K., Karsan A. Notch signaling in cardiac development. Circ. Res. 2008, 102(10):1169-1181.
-
(2008)
Circ. Res.
, vol.102
, Issue.10
, pp. 1169-1181
-
-
Niessen, K.1
Karsan, A.2
-
91
-
-
33845877157
-
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
-
Noguera-Troise I., Daly C., Papadopoulos N.J., Coetzee S., Boland P., Gale N.W., Lin H.C., Yancopoulos G.D., Thurston G. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature 2006, 444(7122):1032-1037.
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1032-1037
-
-
Noguera-Troise, I.1
Daly, C.2
Papadopoulos, N.J.3
Coetzee, S.4
Boland, P.5
Gale, N.W.6
Lin, H.C.7
Yancopoulos, G.D.8
Thurston, G.9
-
92
-
-
4744358492
-
Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression
-
Noseda M., Chang L., McLean G., Grim J.E., Clurman B.E., Smith L.L., Karsan A. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol. Cell. Biol. 2004, 24(20):8813-8822.
-
(2004)
Mol. Cell. Biol.
, vol.24
, Issue.20
, pp. 8813-8822
-
-
Noseda, M.1
Chang, L.2
McLean, G.3
Grim, J.E.4
Clurman, B.E.5
Smith, L.L.6
Karsan, A.7
-
93
-
-
11144354703
-
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation
-
Noseda M., McLean G., Niessen K., Chang L., Pollet I., Montpetit R., Shahidi R., Dorovini-Zis K., Li L., Beckstead B., Durand R.E., Hoodless P.A., Karsan A. Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ. Res. 2004, 94(7):910-917.
-
(2004)
Circ. Res.
, vol.94
, Issue.7
, pp. 910-917
-
-
Noseda, M.1
McLean, G.2
Niessen, K.3
Chang, L.4
Pollet, I.5
Montpetit, R.6
Shahidi, R.7
Dorovini-Zis, K.8
Li, L.9
Beckstead, B.10
Durand, R.E.11
Hoodless, P.A.12
Karsan, A.13
-
94
-
-
84896082963
-
From fly wings to targeted cancer therapies: a centennial for notch signaling
-
Ntziachristos P., Lim J.S., Sage J., Aifantis I. From fly wings to targeted cancer therapies: a centennial for notch signaling. Cancer Cell 2014, 25(3):318-334.
-
(2014)
Cancer Cell
, vol.25
, Issue.3
, pp. 318-334
-
-
Ntziachristos, P.1
Lim, J.S.2
Sage, J.3
Aifantis, I.4
-
95
-
-
37549037911
-
Off the beaten pathway: the complex cross talk between Notch and NF-kappaB
-
Osipo C., Golde T.E., Osborne B.A., Miele L.A. Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Lab. Invest. 2008, 88:11-17.
-
(2008)
Lab. Invest.
, vol.88
, pp. 11-17
-
-
Osipo, C.1
Golde, T.E.2
Osborne, B.A.3
Miele, L.A.4
-
96
-
-
77955446278
-
Hes1, a new target for interleukin 1beta in chondrocytes
-
Ottaviani S., Tahiri K., Frazier A., Hassaine Z.N., Dumontier M.F., et al. Hes1, a new target for interleukin 1beta in chondrocytes. Ann. Rheum. Dis. 2010, 69:1488-1494.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1488-1494
-
-
Ottaviani, S.1
Tahiri, K.2
Frazier, A.3
Hassaine, Z.N.4
Dumontier, M.F.5
-
97
-
-
77958128428
-
Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages
-
Outtz H.H., Wu J.K., Wang X., Kitajewski J. Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages. J. Immunol. 2010, 185(7):4363-4373.
-
(2010)
J. Immunol.
, vol.185
, Issue.7
, pp. 4363-4373
-
-
Outtz, H.H.1
Wu, J.K.2
Wang, X.3
Kitajewski, J.4
-
98
-
-
84914818823
-
Senescent cells: SASPected drivers of age-related pathologies
-
Ovadya Y., Krizhanovsky V. Senescent cells: SASPected drivers of age-related pathologies. Biogerontology 2014, 15(6):627-642.
-
(2014)
Biogerontology
, vol.15
, Issue.6
, pp. 627-642
-
-
Ovadya, Y.1
Krizhanovsky, V.2
-
99
-
-
84959201358
-
Notch signaling mediates crosstalk between endothelial cells and macrophages via Dll4 and IL6 in cardiac microvascular inflammation
-
Pabois A., Pagie S., Gérard N., Laboisse C., Pattier S., Hulin P., Nedellec S., Toquet C., Charreau B. Notch signaling mediates crosstalk between endothelial cells and macrophages via Dll4 and IL6 in cardiac microvascular inflammation. Biochem. Pharmacol. 2016, 104:95-107.
-
(2016)
Biochem. Pharmacol.
, vol.104
, pp. 95-107
-
-
Pabois, A.1
Pagie, S.2
Gérard, N.3
Laboisse, C.4
Pattier, S.5
Hulin, P.6
Nedellec, S.7
Toquet, C.8
Charreau, B.9
-
100
-
-
84923164397
-
The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health?
-
Padhee M., Zhang S., Lie S., Wang K.C., Botting K.J., McMillen I.C., MacLaughlin S.M., Morrison J.L. The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health?. Nutrients 2015, 7(3):1378-1425.
-
(2015)
Nutrients
, vol.7
, Issue.3
, pp. 1378-1425
-
-
Padhee, M.1
Zhang, S.2
Lie, S.3
Wang, K.C.4
Botting, K.J.5
McMillen, I.C.6
MacLaughlin, S.M.7
Morrison, J.L.8
-
101
-
-
38349075227
-
Notch signaling is activated by TLR stimulation and regulates macrophage functions
-
Palaga T., Buranaruk C., Rengpipat S., Fauq A.H., Golde T.E., et al. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur. J. Immunol. 2008, 38:174-183.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 174-183
-
-
Palaga, T.1
Buranaruk, C.2
Rengpipat, S.3
Fauq, A.H.4
Golde, T.E.5
-
102
-
-
84951284076
-
The development and maintenance of resident macrophages
-
Perdiguero E.G., Geissmann F. The development and maintenance of resident macrophages. Nat. Immunol. 2015, 17(December (1)):2-8.
-
(2015)
Nat. Immunol.
, vol.17
, Issue.December 1
, pp. 2-8
-
-
Perdiguero, E.G.1
Geissmann, F.2
-
103
-
-
79251563204
-
Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis
-
Piggott K., Deng J., Warrington K., Younge B., Kubo J.T., Desai M., Goronzy J.J., Weyand C.M. Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. Circulation 2011, 123(3):309-318.
-
(2011)
Circulation
, vol.123
, Issue.3
, pp. 309-318
-
-
Piggott, K.1
Deng, J.2
Warrington, K.3
Younge, B.4
Kubo, J.T.5
Desai, M.6
Goronzy, J.J.7
Weyand, C.M.8
-
104
-
-
84896517343
-
Fetal origin of vascular aging
-
Pitale S., Sahasrabuddhe A. Fetal origin of vascular aging. Indian J. Endocrinol. Metab. 2011, 15(October (Suppl. 4)):S289-97.
-
(2011)
Indian J. Endocrinol. Metab.
, vol.15
, Issue.October Suppl. 4
, pp. S289-S297
-
-
Pitale, S.1
Sahasrabuddhe, A.2
-
105
-
-
56049092014
-
Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms
-
Poellinger L., Lendahl U. Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms. Curr. Opin. Genet. Dev. 2008, 18(5):449-454.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, Issue.5
, pp. 449-454
-
-
Poellinger, L.1
Lendahl, U.2
-
106
-
-
84856229757
-
Telomerase reverse transcriptase upregulation attenuates astrocyte proliferation and promotes neuronal survival in the hypoxic-ischemic rat brain
-
Qu Y., Duan Z., Zhao F., Wei D., Zhang J., Tang B., Li J., Yang C., Mu D. Telomerase reverse transcriptase upregulation attenuates astrocyte proliferation and promotes neuronal survival in the hypoxic-ischemic rat brain. Stroke 2011, 42(12):3542-3550.
-
(2011)
Stroke
, vol.42
, Issue.12
, pp. 3542-3550
-
-
Qu, Y.1
Duan, Z.2
Zhao, F.3
Wei, D.4
Zhang, J.5
Tang, B.6
Li, J.7
Yang, C.8
Mu, D.9
-
107
-
-
57549098228
-
Impaired Notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis
-
Quillard T., Coupel S., Coulon F., Fitau J., Chatelais M., Cuturi M.C., Chiffoleau E., Charreau B. Impaired Notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis. Arterioscler. Thromb. Vasc. Biol. 2008, 28(12):2258-2265.
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, Issue.12
, pp. 2258-2265
-
-
Quillard, T.1
Coupel, S.2
Coulon, F.3
Fitau, J.4
Chatelais, M.5
Cuturi, M.C.6
Chiffoleau, E.7
Charreau, B.8
-
108
-
-
78049440085
-
Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction
-
Quillard T., Devallière J., Coupel S., Charreau B. Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction. Biochem. Pharmacol. 2010, 80(12):2032-2041.
-
(2010)
Biochem. Pharmacol.
, vol.80
, Issue.12
, pp. 2032-2041
-
-
Quillard, T.1
Devallière, J.2
Coupel, S.3
Charreau, B.4
-
109
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke F., Wilson A., Stark G., Bauer M., van Meerwijk J., MacDonald H.R., Aguet M. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 1999, 10(5):547-558.
-
(1999)
Immunity
, vol.10
, Issue.5
, pp. 547-558
-
-
Radtke, F.1
Wilson, A.2
Stark, G.3
Bauer, M.4
van Meerwijk, J.5
MacDonald, H.R.6
Aguet, M.7
-
110
-
-
84856090875
-
Aging, rejuvenation and epigenetic reprogramming: resetting the aging clock
-
Rando T.A., Chang H.Y. Aging, rejuvenation and epigenetic reprogramming: resetting the aging clock. Cell 2012, 148(1-2):46-57.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 46-57
-
-
Rando, T.A.1
Chang, H.Y.2
-
111
-
-
17844384528
-
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A., Talora C., Okuyama R., Nicolas M., Mammucari C., Oh H., Aster J.C., Krishna S., Metzger D., Chambon P., Miele L., Aguet M., Radtke F., Dotto G.P. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 2001, 20(13):3427-3436.
-
(2001)
EMBO J.
, vol.20
, Issue.13
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
Nicolas, M.4
Mammucari, C.5
Oh, H.6
Aster, J.C.7
Krishna, S.8
Metzger, D.9
Chambon, P.10
Miele, L.11
Aguet, M.12
Radtke, F.13
Dotto, G.P.14
-
112
-
-
84995753800
-
Vascular ageing and endothelial cell senescence: molecular mechanisms of physiology and diseases
-
pii: S0047-6374(16)30059-8. 10.1016/j.mad.2016.05.003 [Epub ahead of print]
-
Regina C., Panatta E., Candi E., Melino G., Amelio I., Balistreri C.R., Annicchiarico-Petruzzelli M., Di Daniele N., Ruvolo G. Vascular ageing and endothelial cell senescence: molecular mechanisms of physiology and diseases. Mech. Ageing Dev. 2016, pii: S0047-6374(16)30059-8. 10.1016/j.mad.2016.05.003 [Epub ahead of print].
-
(2016)
Mech. Ageing Dev.
-
-
Regina, C.1
Panatta, E.2
Candi, E.3
Melino, G.4
Amelio, I.5
Balistreri, C.R.6
Annicchiarico-Petruzzelli, M.7
Di Daniele, N.8
Ruvolo, G.9
-
113
-
-
33845907380
-
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
-
Ridgway J., Zhang G., Wu Y., Stawicki S., Liang W.C., Chanthery Y., Kowalski J., Watts R.J., Callahan C., Kasman I., Singh M., Chien M., Tan C., Hongo J.A., de Sauvage F., Plowman G., Yan M. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature 2006, 444(7122):1083-1087.
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1083-1087
-
-
Ridgway, J.1
Zhang, G.2
Wu, Y.3
Stawicki, S.4
Liang, W.C.5
Chanthery, Y.6
Kowalski, J.7
Watts, R.J.8
Callahan, C.9
Kasman, I.10
Singh, M.11
Chien, M.12
Tan, C.13
Hongo, J.A.14
de Sauvage, F.15
Plowman, G.16
Yan, M.17
-
114
-
-
85013080221
-
The role of notch in the cardiovascular system: potential adverse effects of investigational notch inhibitors
-
Rizzo P., Mele D., Caliceti C., Pannella M., Fortini C., Clementz A.G., Morelli M.B., Aquila G., Ameri P., Ferrari R. The role of notch in the cardiovascular system: potential adverse effects of investigational notch inhibitors. Front. Oncol. 2015, 4:384.
-
(2015)
Front. Oncol.
, vol.4
, pp. 384
-
-
Rizzo, P.1
Mele, D.2
Caliceti, C.3
Pannella, M.4
Fortini, C.5
Clementz, A.G.6
Morelli, M.B.7
Aquila, G.8
Ameri, P.9
Ferrari, R.10
-
115
-
-
84904702158
-
Can the TLR-4-mediated signaling pathway be a key inflammatory promoter for sporadic TAA?
-
Ruvolo G., Pisano C., Candore G., Lio D., Palmeri C., Maresi E., Balistreri C.R. Can the TLR-4-mediated signaling pathway be a key inflammatory promoter for sporadic TAA?. Mediators Inflamm. 2014, 2014:349476.
-
(2014)
Mediators Inflamm.
, vol.2014
, pp. 349476
-
-
Ruvolo, G.1
Pisano, C.2
Candore, G.3
Lio, D.4
Palmeri, C.5
Maresi, E.6
Balistreri, C.R.7
-
116
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
Sahlgren C., Gustafsson M.V., Jin S., Poellinger L., Lendahl U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(17):6392-6397.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, Issue.17
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
117
-
-
77952545621
-
Genetics vs. entropy: longevity factors suppress the NF-kappaB-driven entropic aging process
-
Salminen A., Kaarniranta K. Genetics vs. entropy: longevity factors suppress the NF-kappaB-driven entropic aging process. Ageing Res. Rev. 2010, 9:298-314.
-
(2010)
Ageing Res. Rev.
, vol.9
, pp. 298-314
-
-
Salminen, A.1
Kaarniranta, K.2
-
118
-
-
11144350287
-
Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation
-
Sakata T., Sakaguchi H., Tsuda L., Higashitani A., Aigaki T., Matsuno K., Hayashi S. Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation. Curr. Biol. 2004, 14(24):2228-2236.
-
(2004)
Curr. Biol.
, vol.14
, Issue.24
, pp. 2228-2236
-
-
Sakata, T.1
Sakaguchi, H.2
Tsuda, L.3
Higashitani, A.4
Aigaki, T.5
Matsuno, K.6
Hayashi, S.7
-
119
-
-
84961149139
-
Role of Notch signaling in regulating innate immunity and inflammation in health and disease
-
Shang Y., Smith S., Hu X. Role of Notch signaling in regulating innate immunity and inflammation in health and disease. Protein Cell 2016, 7(3):159-174.
-
(2016)
Protein Cell
, vol.7
, Issue.3
, pp. 159-174
-
-
Shang, Y.1
Smith, S.2
Hu, X.3
-
120
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas
-
Sica A., Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J. Clin. Invest. 2012, 122(3):787-795.
-
(2012)
J. Clin. Invest.
, vol.122
, Issue.3
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
121
-
-
84900323323
-
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle
-
Sinha M., Jang Y.C., Oh J., Khong D., Wu E.Y., Manohar R., Miller C., Regalado S.G., Loffredo F.S., Pancoast J.R., Hirshman M.F., Lebowitz J., Shadrach J.L., Cerletti M., Kim M.J., Serwold T., Goodyear L.J., Rosner B., Lee R.T., Wagers A.J. Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science 2014, 344(6184):649-652.
-
(2014)
Science
, vol.344
, Issue.6184
, pp. 649-652
-
-
Sinha, M.1
Jang, Y.C.2
Oh, J.3
Khong, D.4
Wu, E.Y.5
Manohar, R.6
Miller, C.7
Regalado, S.G.8
Loffredo, F.S.9
Pancoast, J.R.10
Hirshman, M.F.11
Lebowitz, J.12
Shadrach, J.L.13
Cerletti, M.14
Kim, M.J.15
Serwold, T.16
Goodyear, L.J.17
Rosner, B.18
Lee, R.T.19
Wagers, A.J.20
more..
-
122
-
-
9444261891
-
Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway
-
Sweeney C., Morrow D., Birney Y.A., Coyle S., Hennessy C., Scheller A., Cummins P.M., Walls D., Redmond E.M., Cahill P.A. Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway. FASEB J. 2004, 18(12):1421-1423.
-
(2004)
FASEB J.
, vol.18
, Issue.12
, pp. 1421-1423
-
-
Sweeney, C.1
Morrow, D.2
Birney, Y.A.3
Coyle, S.4
Hennessy, C.5
Scheller, A.6
Cummins, P.M.7
Walls, D.8
Redmond, E.M.9
Cahill, P.A.10
-
123
-
-
49349097988
-
Notch signaling and diseases: an evolutionary journey from a simple beginning to complex outcomes
-
Talora C., Campese A.F., Bellavia D., Felli M.P., Vacca A., Gulino A., Screpanti I. Notch signaling and diseases: an evolutionary journey from a simple beginning to complex outcomes. Biochim. Biophys. Acta 2008, 1782(9):489-497.
-
(2008)
Biochim. Biophys. Acta
, vol.1782
, Issue.9
, pp. 489-497
-
-
Talora, C.1
Campese, A.F.2
Bellavia, D.3
Felli, M.P.4
Vacca, A.5
Gulino, A.6
Screpanti, I.7
-
124
-
-
84876906640
-
Role of p63 and the Notch pathway in cochlea development and sensorineural deafness
-
Terrinoni A., Serra V., Bruno E., Strasser A., Valente E., Flores E.R., van Bokhoven H., Lu X., Knight R.A., Melino G. Role of p63 and the Notch pathway in cochlea development and sensorineural deafness. Proc. Natl. Acad. Sci. U. S. A. 2013, 110(18):7300-7305.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, Issue.18
, pp. 7300-7305
-
-
Terrinoni, A.1
Serra, V.2
Bruno, E.3
Strasser, A.4
Valente, E.5
Flores, E.R.6
van Bokhoven, H.7
Lu, X.8
Knight, R.A.9
Melino, G.10
-
125
-
-
84975806501
-
Inflammatory networks in ageing, age-related diseases and longevity
-
Vasto S., Candore G., Balistreri C.R., Caruso M., Colonna-Romano G., Grimaldi M.P., Listi F., Nuzzo D., Lio D., Caruso C. Inflammatory networks in ageing, age-related diseases and longevity. Mech. Ageing Dev. 2007, 128(1):83-91.
-
(2007)
Mech. Ageing Dev.
, vol.128
, Issue.1
, pp. 83-91
-
-
Vasto, S.1
Candore, G.2
Balistreri, C.R.3
Caruso, M.4
Colonna-Romano, G.5
Grimaldi, M.P.6
Listi, F.7
Nuzzo, D.8
Lio, D.9
Caruso, C.10
-
126
-
-
84959420599
-
Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
-
Vu Van D., Beier K.C., Pietzke L.J., Al Baz M.S., Feist R.K., Gurka S., Hamelmann E., Kroczek R.A., Hutloff A. Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells. Nat. Commun. 2016, 7:10875.
-
(2016)
Nat. Commun.
, vol.7
, pp. 10875
-
-
Vu Van, D.1
Beier, K.C.2
Pietzke, L.J.3
Al Baz, M.S.4
Feist, R.K.5
Gurka, S.6
Hamelmann, E.7
Kroczek, R.A.8
Hutloff, A.9
-
127
-
-
84921673788
-
The role of Notch receptors in transcriptional regulation
-
Wang H., Zang C., Liu X.S., Aster J.C. The role of Notch receptors in transcriptional regulation. J. Cell. Physiol. 2015, 230(5):982-988.
-
(2015)
J. Cell. Physiol.
, vol.230
, Issue.5
, pp. 982-988
-
-
Wang, H.1
Zang, C.2
Liu, X.S.3
Aster, J.C.4
-
128
-
-
0037189585
-
Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK
-
Wang W., Campos A.H., Prince C.Z., Mou Y., Pollman M.J. Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK. J. Biol. Chem. 2002, 277(26):23165-23171.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.26
, pp. 23165-23171
-
-
Wang, W.1
Campos, A.H.2
Prince, C.Z.3
Mou, Y.4
Pollman, M.J.5
-
129
-
-
0042665946
-
HRT1 modulates vascular smooth muscle cell proliferation and apoptosis
-
Wang W., Prince C.Z., Hu X., Pollman M.J. HRT1 modulates vascular smooth muscle cell proliferation and apoptosis. Biochem. Biophys. Res. Commun. 2003, 308(3):596-601.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.308
, Issue.3
, pp. 596-601
-
-
Wang, W.1
Prince, C.Z.2
Hu, X.3
Pollman, M.J.4
-
130
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng A.P., Ferrando A.A., Lee W., 4th Morris J.P, Silverman L.B., Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004, 306(October (5694)):269-271.
-
(2004)
Science
, vol.306
, Issue.October 5694
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
Blacklow, S.C.7
Look, A.T.8
Aster, J.C.9
-
131
-
-
33746546368
-
C-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
-
Weng A.P., Millholland J.M., Yashiro-Ohtani Y., Arcangeli M.L., Lau A., Wai C., Del Bianco C., Rodriguez C.G., Sai H., Tobias J., Li Y., Wolfe M.S., Shachaf C., Felsher D., Blacklow S.C., Pear W.S., Aster J.C. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev. 2006, 20(15):2096-2109.
-
(2006)
Genes Dev.
, vol.20
, Issue.15
, pp. 2096-2109
-
-
Weng, A.P.1
Millholland, J.M.2
Yashiro-Ohtani, Y.3
Arcangeli, M.L.4
Lau, A.5
Wai, C.6
Del Bianco, C.7
Rodriguez, C.G.8
Sai, H.9
Tobias, J.10
Li, Y.11
Wolfe, M.S.12
Shachaf, C.13
Felsher, D.14
Blacklow, S.C.15
Pear, W.S.16
Aster, J.C.17
-
132
-
-
58449098702
-
Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing
-
Wong L.S., Oeseburg H., de Boer R.A., van Gilst W.H., van Veldhuisen D.J., van der Harst P. Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing. Cardiovasc. Res. 2009, 81(2):244-252.
-
(2009)
Cardiovasc. Res.
, vol.81
, Issue.2
, pp. 244-252
-
-
Wong, L.S.1
Oeseburg, H.2
de Boer, R.A.3
van Gilst, W.H.4
van Veldhuisen, D.J.5
van der Harst, P.6
-
133
-
-
0033662392
-
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors
-
Wu L., Aster J.C., Blacklow S.C., Lake R., Artavanis-Tsakonas S., Griffin J.D. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 2000, 26(4):484-489.
-
(2000)
Nat. Genet.
, vol.26
, Issue.4
, pp. 484-489
-
-
Wu, L.1
Aster, J.C.2
Blacklow, S.C.3
Lake, R.4
Artavanis-Tsakonas, S.5
Griffin, J.D.6
-
134
-
-
0032897080
-
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
-
Xue Y., Gao X., Lindsell C.E., Norton C.R., Chang B., Hicks C., Gendron-Maguire M., Rand E.B., Weinmaster G., Gridley T. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum. Mol. Genet. 1999, 8(5):723-730.
-
(1999)
Hum. Mol. Genet.
, vol.8
, Issue.5
, pp. 723-730
-
-
Xue, Y.1
Gao, X.2
Lindsell, C.E.3
Norton, C.R.4
Chang, B.5
Hicks, C.6
Gendron-Maguire, M.7
Rand, E.B.8
Weinmaster, G.9
Gridley, T.10
-
135
-
-
0242580961
-
The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death
-
Yan B., Zemskova M., Holder S., Chin V., Kraft A., Koskinen P.J., Lilly M. The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. J. Biol. Chem. 2003, 278(46):45358-45367.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.46
, pp. 45358-45367
-
-
Yan, B.1
Zemskova, M.2
Holder, S.3
Chin, V.4
Kraft, A.5
Koskinen, P.J.6
Lilly, M.7
-
136
-
-
0032161624
-
P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
Yang A., Kaghad M., Wang Y., Gillett E., Fleming M.D., Dötsch V., Andrews N.C., Caput D., McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol. Cell 1998, 2(3):305-316.
-
(1998)
Mol. Cell
, vol.2
, Issue.3
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dötsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
137
-
-
84867720848
-
Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart
-
Yang J., Bücker S., Jungblut B., Böttger T., Cinnamon Y., Tchorz J., Müller M., Bettler B., Harvey R., Sun Q.Y., Schneider A., Braun T. Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart. Cardiovasc. Res. 2012, 96(2):276-285.
-
(2012)
Cardiovasc. Res.
, vol.96
, Issue.2
, pp. 276-285
-
-
Yang, J.1
Bücker, S.2
Jungblut, B.3
Böttger, T.4
Cinnamon, Y.5
Tchorz, J.6
Müller, M.7
Bettler, B.8
Harvey, R.9
Sun, Q.Y.10
Schneider, A.11
Braun, T.12
-
138
-
-
18344377007
-
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
-
You L.R., Lin F.J., Lee C.T., DeMayo F.J., Tsai M.J., Tsai S.Y. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature 2005, 435(7038):98-104.
-
(2005)
Nature
, vol.435
, Issue.7038
, pp. 98-104
-
-
You, L.R.1
Lin, F.J.2
Lee, C.T.3
DeMayo, F.J.4
Tsai, M.J.5
Tsai, S.Y.6
-
139
-
-
22244460522
-
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
-
Zeng Q., Li S., Chepeha D.B., Giordano T.J., Li J., Zhang H., Polverini P.J., Nor J., Kitajewski J., Wang C.Y. Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell 2005, 8(1):13-23.
-
(2005)
Cancer Cell
, vol.8
, Issue.1
, pp. 13-23
-
-
Zeng, Q.1
Li, S.2
Chepeha, D.B.3
Giordano, T.J.4
Li, J.5
Zhang, H.6
Polverini, P.J.7
Nor, J.8
Kitajewski, J.9
Wang, C.Y.10
-
140
-
-
84863137323
-
Notch signal suppresses TLR-triggered inflammatory responses in macrophages by inhibiting ERK1/2-mediated NF-kappaB activation
-
Zhang Q., Wang C., Liu Z., Liu X., Han C., et al. Notch signal suppresses TLR-triggered inflammatory responses in macrophages by inhibiting ERK1/2-mediated NF-kappaB activation. J. Biol. Chem. 2012, 287:6208-6217.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 6208-6217
-
-
Zhang, Q.1
Wang, C.2
Liu, Z.3
Liu, X.4
Han, C.5
-
141
-
-
84891545176
-
Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation
-
Zhao C., Guo H., Li J., Myint T., Pittman W., Yang L., Zhong W., Schwartz R.J., Schwarz J.J., Singer H.A., Tallquist M.D., Wu M. Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development 2014, 141(2):281-295.
-
(2014)
Development
, vol.141
, Issue.2
, pp. 281-295
-
-
Zhao, C.1
Guo, H.2
Li, J.3
Myint, T.4
Pittman, W.5
Yang, L.6
Zhong, W.7
Schwartz, R.J.8
Schwarz, J.J.9
Singer, H.A.10
Tallquist, M.D.11
Wu, M.12
-
142
-
-
84893350246
-
Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration
-
Zhao L., Borikova A.L., Ben-Yair R., Guner-Ataman B., MacRae C.A., Lee R.T., Burns C.G., Burns C.E. Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration. Proc. Natl. Acad. Sci. U. S. A. 2014, 111(4):1403-1408.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, Issue.4
, pp. 1403-1408
-
-
Zhao, L.1
Borikova, A.L.2
Ben-Yair, R.3
Guner-Ataman, B.4
MacRae, C.A.5
Lee, R.T.6
Burns, C.G.7
Burns, C.E.8
-
143
-
-
47649118102
-
Notch-dependent control of myelopoiesis is regulated by fucosylation
-
Zhou L., Li L.W., Yan Q., Petryniak B., Man Y., Su C., Shim J., Chervin S., Lowe J.B. Notch-dependent control of myelopoiesis is regulated by fucosylation. Blood 2008, 112(2):308-319.
-
(2008)
Blood
, vol.112
, Issue.2
, pp. 308-319
-
-
Zhou, L.1
Li, L.W.2
Yan, Q.3
Petryniak, B.4
Man, Y.5
Su, C.6
Shim, J.7
Chervin, S.8
Lowe, J.B.9
-
144
-
-
2942525073
-
Identification of Flk-1 target genes in vasculogenesis: pim-1 is required for endothelial and mural cell differentiation in vitro
-
Zippo A., De Robertis A., Bardelli M., Galvagni F., Oliviero S. Identification of Flk-1 target genes in vasculogenesis: pim-1 is required for endothelial and mural cell differentiation in vitro. Blood 2004, 103(12):4536-4544.
-
(2004)
Blood
, vol.103
, Issue.12
, pp. 4536-4544
-
-
Zippo, A.1
De Robertis, A.2
Bardelli, M.3
Galvagni, F.4
Oliviero, S.5
-
145
-
-
84871593869
-
Notch signaling in descending thoracic aortic aneurysm and dissection
-
Zou S., Ren P., Nguyen M., Coselli J.S., Shen Y.H., LeMaire S.A. Notch signaling in descending thoracic aortic aneurysm and dissection. PLoS One 2012, 7(12):e52833.
-
(2012)
PLoS One
, vol.7
, Issue.12
-
-
Zou, S.1
Ren, P.2
Nguyen, M.3
Coselli, J.S.4
Shen, Y.H.5
LeMaire, S.A.6
|