-
1
-
-
0345059168
-
Functional regulation of p73 and p63: Development and cancer
-
DOI 10.1016/j.tibs.2003.10.004
-
Melino G, Lu X, Gasco M, Crook T, Knight RA (2003) Functional regulation of p73 and p63: Development and cancer. Trends Biochem Sci 28(12):663-670. (Pubitemid 37500901)
-
(2003)
Trends in Biochemical Sciences
, vol.28
, Issue.12
, pp. 663-670
-
-
Melino, G.1
Lu, X.2
Gasco, M.3
Crook, T.4
Knight, R.A.5
-
2
-
-
0032161624
-
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
Yang A, et al. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2(3):305-316. (Pubitemid 128379271)
-
(1998)
Molecular Cell
, vol.2
, Issue.3
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dotsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
3
-
-
0031852337
-
Cloning and functional analysis of human p51, which structurally and functionally resembles p53
-
DOI 10.1038/nm0798-839
-
Osada M, et al. (1998) Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med 4(7):839-843. (Pubitemid 28331028)
-
(1998)
Nature Medicine
, vol.4
, Issue.7
, pp. 839-843
-
-
Osada, M.1
Ohba, M.2
Kawahara, C.3
Ishioka, C.4
Kanamaru, R.5
Katoh, I.6
Ikawa, Y.7
Nimura, Y.8
Nakagawara, A.9
Obinata, M.10
Ikawa, S.11
-
4
-
-
0036892018
-
Complex transcriptional effects of p63 isoforms: Identification of novel activation and repression domains
-
DOI 10.1128/MCB.22.24.8659-8668.2002
-
Ghioni P, et al. (2002) Complex transcriptional effects of p63 isoforms: Identification of novel activation and repression domains. Mol Cell Biol 22(24):8659-8668. (Pubitemid 35397180)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.24
, pp. 8659-8668
-
-
Ghioni, P.1
Bolognese, F.2
Duijf, P.H.G.3
Van Bokhoven, H.4
Mantovani, R.5
Guerrini, L.6
-
5
-
-
0032771021
-
p53 Family members p63 and p73 are SAM domain-containing proteins
-
Thanos CD, Bowie JU (1999) p53 Family members p63 and p73 are SAM domain-containing proteins. Protein Sci 8(8):1708-1710. (Pubitemid 29379954)
-
(1999)
Protein Science
, vol.8
, Issue.8
, pp. 1708-1710
-
-
Thanos, C.D.1
Bowie, J.U.2
-
6
-
-
0032744735
-
Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome
-
Celli J, et al. (1999) Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome. Cell 99(2):143-153.
-
(1999)
Cell
, vol.99
, Issue.2
, pp. 143-153
-
-
Celli, J.1
-
7
-
-
0034892604
-
p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation
-
van Bokhoven H, et al. (2001) p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation. Am J Hum Genet 69(3):481-492.
-
(2001)
Am J Hum Genet
, vol.69
, Issue.3
, pp. 481-492
-
-
Van Bokhoven, H.1
-
8
-
-
33745631827
-
Pattern of p63 mutations and their phenotypes - Update
-
Rinne T, Hamel B, van Bokhoven H, Brunner HG (2006) Pattern of p63 mutations and their phenotypes - update. Am J Med Genet A 140(13):1396-1406.
-
(2006)
Am J Med Genet A
, vol.140
, Issue.13
, pp. 1396-1406
-
-
Rinne, T.1
Hamel, B.2
Van Bokhoven, H.3
Brunner, H.G.4
-
9
-
-
0036305571
-
Splitting p63
-
van Bokhoven H, Brunner HG (2002) Splitting p63. Am J Hum Genet 71(1):1-13.
-
(2002)
Am J Hum Genet
, vol.71
, Issue.1
, pp. 1-13
-
-
Brunner, H.G.1
-
10
-
-
0033594491
-
p63 is a p53 homologue required for limb and epidermal morphogenesis
-
DOI 10.1038/19531
-
Mills AA, et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398(6729):708-713. (Pubitemid 29197649)
-
(1999)
Nature
, vol.398
, Issue.6729
, pp. 708-713
-
-
Mills, A.A.1
Zheng, B.2
Wang, X.-J.3
Vogel, H.4
Roop, D.R.5
Bradley, A.6
-
11
-
-
0033594485
-
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
-
DOI 10.1038/19539
-
Yang A, et al. (1999) p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398(6729):714-718. (Pubitemid 29197650)
-
(1999)
Nature
, vol.398
, Issue.6729
, pp. 714-718
-
-
Yang, A.1
Schweitzer, R.2
Sun, D.3
Kaghad, M.4
Walker, N.5
Bronson, R.T.6
Tabin, C.7
Sharpe, A.8
Caput, D.9
Crum, C.10
McKeon, F.11
-
12
-
-
33646797744
-
Differential roles of p63 isoforms in epidermal development: Selective genetic complementation in p63 null mice
-
Candi E, et al. (2006) Differential roles of p63 isoforms in epidermal development: Selective genetic complementation in p63 null mice. Cell Death Differ 13(6):1037-1047.
-
(2006)
Cell Death Differ
, vol.13
, Issue.6
, pp. 1037-1047
-
-
Candi, E.1
-
13
-
-
33744796255
-
p63 regulates an adhesion programme and cell survival in epithelial cells
-
DOI 10.1038/ncb1420, PII N1420
-
Carroll DK, et al. (2006) p63 regulates an adhesion programme and cell survival in epithelial cells. Nat Cell Biol 8(6):551-561. (Pubitemid 43827347)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.6
, pp. 551-561
-
-
Carroll, D.K.1
Carroll, J.S.2
Leong, C.-O.3
Cheng, F.4
Brown, M.5
Mills, A.A.6
Brugge, J.S.7
Ellisen, L.W.8
-
14
-
-
80054878182
-
TAp63 is important for cardiac differentiation of embryonic stem cells and heart development
-
Rouleau M, et al. (2011) TAp63 is important for cardiac differentiation of embryonic stem cells and heart development. Stem Cells 29(11):1672-1683.
-
(2011)
Stem Cells
, vol.29
, Issue.11
, pp. 1672-1683
-
-
Rouleau, M.1
-
15
-
-
33845244180
-
p63 protects the female germ line during meiotic arrest
-
Suh EK, et al. (2006) p63 protects the female germ line during meiotic arrest. Nature 444(7119):624-628.
-
(2006)
Nature
, vol.444
, Issue.7119
, pp. 624-628
-
-
Suh, E.K.1
-
16
-
-
70350506325
-
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death
-
Gonfloni S, et al. (2009) Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med 15(10):1179-1185.
-
(2009)
Nat Med
, vol.15
, Issue.10
, pp. 1179-1185
-
-
Gonfloni, S.1
-
17
-
-
79953058126
-
The p53 family: Guardians of maternal reproduction
-
Levine AJ, Tomasini R, McKeon FD, Mak TW, Melino G (2011) The p53 family: Guardians of maternal reproduction. Nat Rev Mol Cell Biol 12(4):259-265.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.4
, pp. 259-265
-
-
Levine, A.J.1
Tomasini, R.2
McKeon, F.D.3
Mak, T.W.4
Melino, G.5
-
18
-
-
0034979428
-
Split hand/split foot malformation associated with sensorineural deafness, inner and middle ear malformation, hypodontia, congenital vertical talus, and deletion of eight microsatellite markers in 7q21.1-q21.3 [6]
-
Haberlandt E, et al. (2001) Split hand/split foot malformation associated with sensorineural deafness, inner and middle ear malformation, hypodontia, congenital vertical talus, and deletion of eight microsatellite markers in 7q21.1-q21.3. J Med Genet 38(6):405-409. (Pubitemid 32554313)
-
(2001)
Journal of Medical Genetics
, vol.38
, Issue.6
, pp. 405-409
-
-
Haberlandt, E.1
Loffler, J.2
Hirst-Stadlmann, A.3
Stockl, B.4
Judmaier, W.5
Fischer, H.6
Heinz-Erian, P.7
Muller, T.8
Utermann, G.9
Smith, R.J.H.10
Janecke, A.R.11
-
19
-
-
0033002783
-
Genetic diseases and gene knockouts reveal diverse connexin functions
-
DOI 10.1146/annurev.physiol.61.1.283
-
White TW, Paul DL (1999) Genetic diseases and gene knockouts reveal diverse connexin functions. Annu Rev Physiol 61:283-310. (Pubitemid 29143172)
-
(1999)
Annual Review of Physiology
, vol.61
, pp. 283-310
-
-
White, T.W.1
Paul, D.L.2
-
20
-
-
84860439469
-
The primordial follicle reserve is not renewed after chemical or γ-irradiation mediated depletion
-
Kerr JB, et al. (2012) The primordial follicle reserve is not renewed after chemical or γ-irradiation mediated depletion. Reproduction 143(4):469-476.
-
(2012)
Reproduction
, vol.143
, Issue.4
, pp. 469-476
-
-
Kerr, J.B.1
-
21
-
-
34547513872
-
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2
-
DOI 10.1073/pnas.0703458104
-
Candi E, et al. (2007) DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci USA 104(29):11999-12004. (Pubitemid 47185619)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.29
, pp. 11999-12004
-
-
Candi, E.1
Rufini, A.2
Terrinoni, A.3
Giamboi-Miraglia, A.4
Lena, A.M.5
Mantovani, R.6
Knight, R.7
Melino, G.8
-
22
-
-
0037041392
-
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
DOI 10.1038/416560a
-
Flores ER, et al. (2002) p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416(6880):560-564. (Pubitemid 34288861)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
23
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
Jarriault S, et al. (1995) Signalling downstream of activated mammalian Notch. Nature 377(6547):355-358.
-
(1995)
Nature
, vol.377
, Issue.6547
, pp. 355-358
-
-
Jarriault, S.1
-
24
-
-
0033193157
-
The Notch-Hes pathway in mammalian neural development
-
Kageyama R, Ohtsuka T (1999) The Notch-Hes pathway in mammalian neural development. Cell Res 9(3):179-188. (Pubitemid 129623500)
-
(1999)
Cell Research
, vol.9
, Issue.3
, pp. 179-188
-
-
Kageyama, R.1
Ohtsuka, T.2
-
25
-
-
0033021954
-
Notch signalling pathway mediates hair cell development in mammalian cochlea
-
DOI 10.1038/6804
-
Lanford PJ, et al. (1999) Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat Genet 21(3):289-292. (Pubitemid 29124936)
-
(1999)
Nature Genetics
, vol.21
, Issue.3
, pp. 289-292
-
-
Lanford, P.J.1
Lan, Y.2
Jiang, R.3
Lindsell, C.4
Weinmaster, G.5
Gridley, T.6
Kelley, M.W.7
-
26
-
-
79960336511
-
Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias
-
Browne G, et al. (2011) Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias. J Cell Sci 124(Pt 13):2200-2207.
-
(2011)
J Cell Sci
, vol.124
, Issue.PART 13
, pp. 2200-2207
-
-
Browne, G.1
-
27
-
-
81955167348
-
Functional characterization of a novel TP63 mutation in a family with overlapping features of Rapp-Hodgkin/AEC/ADULT syndromes
-
Serra V, et al. (2011) Functional characterization of a novel TP63 mutation in a family with overlapping features of Rapp-Hodgkin/AEC/ADULT syndromes. Am J Med Genet A 155A(12):3104-3109.
-
(2011)
Am J Med Genet A
, vol.155 A
, Issue.12
, pp. 3104-3109
-
-
Serra, V.1
-
28
-
-
0034029614
-
Autoregulation and multiple enhancers control Math1 expression in the developing nervous system
-
Helms AW, Abney AL, Ben-Arie N, Zoghbi HY, Johnson JE (2000) Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development 127(6):1185-1196. (Pubitemid 30179509)
-
(2000)
Development
, vol.127
, Issue.6
, pp. 1185-1196
-
-
Helms, A.W.1
Abney, A.L.2
Ben-Arie, N.3
Zoghbi, H.Y.4
Johnson, J.E.5
-
29
-
-
74449088062
-
Induction of TAp63 by histone deacetylase inhibitors
-
Sayan BS, et al. (2010-1751) Induction of TAp63 by histone deacetylase inhibitors. Biochem Biophys Res Commun 391(4):1748-1751.
-
(1751)
Biochem Biophys Res Commun
, vol.391
, Issue.4
, pp. 1748-1751
-
-
Sayan, B.S.1
-
30
-
-
80053619221
-
Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification
-
Notari M, et al. (2011) Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification. Proc Natl Acad Sci USA 108(40):16645-16650.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.40
, pp. 16645-16650
-
-
Notari, M.1
-
31
-
-
0035400075
-
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear
-
Zine A, et al. (2001) Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear. J Neurosci 21(13):4712-4720. (Pubitemid 32565629)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.13
, pp. 4712-4720
-
-
Zine, A.1
Aubert, A.2
Qiu, J.3
Therianos, S.4
Guillemot, F.5
Kageyama, R.6
De Ribaupierre, F.7
-
32
-
-
0032054855
-
Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split
-
DOI 10.1006/geno.1998.5213
-
Nishimura M, et al. (1998) Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split. Genomics 49(1):69-75. (Pubitemid 28194438)
-
(1998)
Genomics
, vol.49
, Issue.1
, pp. 69-75
-
-
Nishimura, M.1
Isaka, F.2
Ishibashi, M.3
Tomita, K.4
Tsuda, H.5
Nakanishi, S.6
Kageyama, R.7
-
33
-
-
36049033669
-
Cellular commitment and differentiation in the organ of Corti
-
Kelley MW (2007) Cellular commitment and differentiation in the organ of Corti. Int J Dev Biol 51(6-7):571-583.
-
(2007)
Int J Dev Biol
, vol.51
, Issue.6-7
, pp. 571-583
-
-
Kelley, M.W.1
-
34
-
-
77957663412
-
Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear
-
Pan W, Jin Y, Stanger B, Kiernan AE (2010) Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear. Proc Natl Acad Sci USA 107(36):15798-15803.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.36
, pp. 15798-15803
-
-
Pan, W.1
Jin, Y.2
Stanger, B.3
Kiernan, A.E.4
-
35
-
-
0033845467
-
Notch signaling regulates the pattern of auditory hair cell differentiation in mammals
-
Zine A, Van De Water TR, de Ribaupierre F (2000) Notch signaling regulates the pattern of auditory hair cell differentiation in mammals. Development 127(15):3373-3383. (Pubitemid 30649547)
-
(2000)
Development
, vol.127
, Issue.15
, pp. 3373-3383
-
-
Zine, A.1
Van De, W.T.R.2
De Ribaupierre, F.3
-
36
-
-
0030669218
-
Math1 is essential for genesis of cerebellar granule neurons
-
DOI 10.1038/36579
-
Ben-Arie N, et al. (1997) Math1 is essential for genesis of cerebellar granule neurons. Nature 390(6656):169-172. (Pubitemid 27507985)
-
(1997)
Nature
, vol.390
, Issue.6656
, pp. 169-172
-
-
Ben-Arie, N.1
Bellen, H.J.2
Armstrong, D.L.3
McCall, A.E.4
Gordadze, P.R.5
Guo, Q.6
Matzuk, M.M.7
Zoghbi, H.Y.8
-
37
-
-
0033546004
-
Math1: An essential gene for the generation of inner ear hair cells
-
Bermingham NA, et al. (1999) Math1: An essential gene for the generation of inner ear hair cells. Science 284(5421):1837-1841.
-
(1999)
Science
, vol.284
, Issue.5421
, pp. 1837-1841
-
-
Bermingham, N.A.1
-
38
-
-
38749101987
-
Notch signaling: Its role in epidermal homeostasis and in the pathogenesis of skin diseases
-
DOI 10.1016/j.jdermsci.2007.05.017, PII S0923181107002101
-
Okuyama R, Tagami H, Aiba S (2008) Notch signaling: Its role in epidermal homeostasis and in the pathogenesis of skin diseases. J Dermatol Sci 49(3):187-194. (Pubitemid 351179207)
-
(2008)
Journal of Dermatological Science
, vol.49
, Issue.3
, pp. 187-194
-
-
Okuyama, R.1
Tagami, H.2
Aiba, S.3
-
39
-
-
0031889206
-
Progenitors of dorsal commissural interneurons are defined by MATH1 expression
-
Helms AW, Johnson JE (1998) Progenitors of dorsal commissural interneurons are defined by MATH1 expression. Development 125(5):919-928. (Pubitemid 28143266)
-
(1998)
Development
, vol.125
, Issue.5
, pp. 919-928
-
-
Helms, A.W.1
Johnson, J.E.2
-
40
-
-
0242410719
-
p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa
-
DOI 10.1126/science.1090072
-
Villunger A, et al. (2003) p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302(5647):1036-1038. (Pubitemid 37386194)
-
(2003)
Science
, vol.302
, Issue.5647
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
41
-
-
44049095767
-
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
-
DOI 10.1038/cdd.2008.16, PII CDD200816
-
Michalak EM, Villunger A, Adams JM, Strasser A (2008) In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ 15(6):1019-1029. (Pubitemid 351712606)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.6
, pp. 1019-1029
-
-
Michalak, E.M.1
Villunger, A.2
Adams, J.M.3
Strasser, A.4
-
42
-
-
67649159970
-
TAp63 prevents premature aging by promoting adult stem cell maintenance
-
Su X, et al. (2009) TAp63 prevents premature aging by promoting adult stem cell maintenance. Cell Stem Cell 5(1):64-75.
-
(2009)
Cell Stem Cell
, vol.5
, Issue.1
, pp. 64-75
-
-
Su, X.1
-
43
-
-
22744459472
-
TAp63α induces apoptosis by activating signaling via death receptors and mitochondria
-
DOI 10.1038/sj.emboj.7600708
-
Gressner O, et al. (2005) TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. EMBO J 24(13):2458-2471. (Pubitemid 41032596)
-
(2005)
EMBO Journal
, vol.24
, Issue.13
, pp. 2458-2471
-
-
Gressner, O.1
Schilling, T.2
Lorenz, K.3
Schleithoff, E.S.4
Koch, A.5
Schulze-Bergkamen, H.6
Lena, A.M.7
Candi, E.8
Terrinoni, A.9
Catani, M.V.10
Oren, M.11
Melino, G.12
Krammer, P.H.13
Stremmel, W.14
Muller, M.15
-
44
-
-
33845689232
-
p63 is upstream of IKKα in epidermal development
-
DOI 10.1242/jcs.03265
-
Candi E, et al. (2006) p63 is upstream of IKK alpha in epidermal development. J Cell Sci 119(Pt 22):4617-4622. (Pubitemid 44964258)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.22
, pp. 4617-4622
-
-
Candi, E.1
Terrinoni, A.2
Rufini, A.3
Chikh, A.4
Lena, A.M.5
Suzuki, Y.6
Sayan, B.S.7
Knight, R.A.8
Melino, G.9
|