Pin1 promotes neuronal death in stroke by stabilizing notch intracellular domain

Annals of Neurology

Volumn 77, Issue 3, 2015, Pages 504-516

  Baik, Sang Ha ^a   Fane, Mitchell ^b   Park, Joon Hyung ^a   Cheng, Yi Lin ^b   Fann, David Yang Wei ^b   Yun, Ui Jeong ^a   Choi, Yuri ^a   Park, Jong Sung ^a   Chai, Bing Han ^b   Park, Jin Su ^a   Back, Seung Hyun ^a   Jeong, Jae In ^a   Jang, Ye Jin ^a   Bahn, Gahee ^a   Lee, Joo Yong ^c   Li, Yu I ^d   Sobey, Christopher G ^e   Uchida, Takafumi ^f   Park, Jae Hyung ^a   Kim, Hong Tae ^a   Tang, Sung Chun ^g   Arumugam, Thiruma V ^a,b,h   Jo, Dong Gyu ^a   more..

^a Sungkyunkwan University   (South Korea)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c Asan Medical Center   (South Korea)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e MONASH UNIVERSITY   (Australia)

^f TOHOKU UNIVERSITY   (Japan)

^g NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^h NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; F BOX PROTEIN; GAMMA SECRETASE INHIBITOR; JUGLONE; MUTANT PROTEIN; NOTCH1 INTRACELLULAR DOMAIN; NOTCH1 RECEPTOR; PEPTIDYLPROLYL ISOMERASE PIN1; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; NOTCH1 PROTEIN, MOUSE; PEPTIDYLPROLYL ISOMERASE; SECRETASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; BRAIN DAMAGE; BRAIN ISCHEMIA; CELL HYPOXIA; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DELETION MUTANT; EMBRYO; EXPERIMENTAL STROKE; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MOUSE EMBRYO; MOUSE MODEL; NERVE CELL NECROSIS; NONHUMAN; POLYUBIQUITINATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BRAIN CORTEX; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DISEASE MODEL; GENETICS; ISCHEMIA; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; STROKE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; HUMANS; ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PEPTIDYLPROLYL ISOMERASE; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; STROKE;

EID: 84923793318     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.24347     Document Type: Article

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