Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity

Nature

Volumn 435, Issue 7038, 2005, Pages 98-104

  You, Li Ru ^a   Lin, Fu Jung ^a   Lee, Christopher T ^a   DeMayo, Francesco J ^a   Tsai, Ming Jer ^a   Tsai, Sophia Y ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; BLOOD VESSELS; CELLS; GENETIC ENGINEERING; NEUROLOGY;

ARTERIES; CELL CLUSTERS; NUCLEAR RECEPTORS; VEINS;

MOLECULAR BIOLOGY;

CELL NUCLEUS RECEPTOR; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; NEUROPILIN 1; NOTCH RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NR2F2; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; DNA BINDING PROTEIN; MEMBRANE PROTEIN; NR2F2 PROTEIN, MOUSE; STEROID RECEPTOR;

MEDICINE;

ANIMAL CELL; ANIMAL TISSUE; ARTERY; ARTICLE; EMBRYO; ENDOTHELIUM; ENDOTHELIUM CELL; EPHRIN B2 GENE; EPHRIN RECEPTOR B4 GENE; GENE; GENE INDUCTION; GENETIC REGULATION; HEMATOPOIETIC CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; VEIN; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; VASCULAR ENDOTHELIUM;

ANIMALIA; GALLUS GALLUS; MUS MUSCULUS;

ANIMALS; ARTERIES; CELL DIFFERENTIATION; COUP TRANSCRIPTION FACTOR II; COUP TRANSCRIPTION FACTORS; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; NEUROPILIN-1; ORGAN SPECIFICITY; RECEPTORS, NOTCH; RECEPTORS, STEROID; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; VEINS;

EID: 18344377007     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03511     Document Type: Article

References (27)

1. Lawson, N. D. et al. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128, 3673-3683 (2001).
2. Gerety, S. S. & Anderson, D. J. Cardiovascular ephrinB2 function is essential for embryonic angiogenesis. Development 129, 1397-1410 (2002).
3. Lawson, N. D., Vogel, A. M. & Weinstein, B. M. Sonic hedgehog and vascular endothelium growth factor act upstream of Notch pathway during arterial endothelial differentiation. Dev. Cell 3, 127-136 (2002).
4. Gu, C. et al. Neuropilin-1 conveys Semaphorin and VEGF signaling during neural and cardiovascular development. Dev. Cell 5, 45-57 (2003).
5. Pereira, F. A., Qiu, Y. H., Chou, G., Tsai, M.-J. & Tsai, S. Y. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 13, 1037-1049 (1999).
6. Takamoto, N. et al. COUP-TFII is essential for radial and anterior-posterior patterning of the stomach. Development 132, 2179-2182 (2005).
7. Sato, T. N. et al. Distinct roles of the receptor kinase Tie-1 and Tie-2 in blood vessel formation. Nature 376, 70-74 (1995).
8. Suri, C. et al. Requisite role of angiopoietin-1, a ligand for TIE2 receptor, during embryonic angiogenesis. Cell 87, 1171-1180 (1996).
9. Kisanuki, Y. Y. et al. Tie2-Cre transgenic mice: anew model for endothelial cell-lineage analysis in vivo. Dev. Biol. 230, 230-242 (2001).
10. Huppert, S. S. et al. Embryonic lethality in mice homozygous for a processing-deficient allele of NotchI. Nature 405, 966-970 (2000).
11. Krebs, L. T. et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14, 1343-1352 (2000).
12. Xue, Y. et al. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum. Mol. Genet. 8, 723-730 (1999).
13. Villa, N. et al. Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. Mech. Dev. 108, 161-164 (2001).
14. Wang, H. U., Chen, Z.-F. & Anderson, D. J. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93, 741-753 (1998).
15. Gerety, S. S., Wang, H. U., Chen, Z.-F. & Anderson, D. J. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol. Cell 4, 403-414 (1999).
16. Shabby, F. et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66 (1995).
17. Kawasaki, T. et al. A requirement for neuropilin-1 in embryonic vessel formation. Development 126, 4895-4902 (1999).
18. Zhong, T. P., Childs, S., Leu, J. P. & Fishman, M. C. Gridlock signalling pathway fashions the first embryonic artery. Nature 414, 216-220 (2001).
19. Fischer, A., Schumacher, N., Maier, M., Sendtner, M. & Gessler, M. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 18, 901-911 (2004).
20. Garcia-Porrero, J. A., Godin, I. E. & Dieterlen-Iievre, F. Potential intraembryonic hemogenic sites at pre-liver stages in the mouse. Anat. Embryol. (Berl.) 192, 427-435 (1995).
21. + hematopoietic cells in the early human embryo. Blood 87, 67-72 (1996).
22. Medvinsky, A. L., Samoylina, N. L., Muller, A. M. & Dzierzak, E. A. An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature 364, 64-67 (1993).
23. Godin, I. E., Garcia-Porrero, J. A., Coutinho, A., Dieterlen-Iievre, F. & Macros, M. A. Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors. Nature 364, 67-69 (1993).
24. Zhang, J. et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425, 836-841 (2003).
25. Calvi, L. M. et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425, 841-846 (2003).
26. Hogan, B. L. M., Beddington, R. S. P., Costantini, E. & Lacy, E. Manipulating the Mouse Embryo, a Laboratory Manual (Cold Spring Harbor Laboratory Press, New Yolk, 1994).
27. Adams, R. H. Molecular control of arterial-venous blood vessel identity. J. Anat. 202, 105-112 (2003).