Is the mean blood leukocyte telomere length a predictor for sporadic thoracic aortic aneurysm? Data from a preliminary study

Rejuvenation Research

Volumn 15, Issue 2, 2012, Pages 170-173

  Balistreri, Carmela Rita ^a   Pisano, Calogera ^a   Merlo, Daniele ^a   Fattouch, Khalil ^a   Caruso, Marco ^a   Incalcaterra, Egle ^a   Colonna Romano, Giuseppina ^a   Candore, Giuseppina ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGING; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PREDICTOR VARIABLE; PRIORITY JOURNAL; RISK ASSESSMENT; TELOMERE; TELOMERE SHORTENING; THORACIC AORTA ANEURYSM;

AGED; AGING; AORTIC ANEURYSM, THORACIC; CASE-CONTROL STUDIES; CELL AGING; DNA; DNA DAMAGE; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; RECOMBINATION, GENETIC; TELOMERE; VASCULAR DISEASES;

EID: 84860264551     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2011.1273     Document Type: Article

References (16)

1. Ince H, Nienaber CA. Etiology, pathogenesis and management of thoracic aortic aneurysm. Nat Clin Pract Cardiovasc Med 2007;4:418-427
2. El-Hamamsy I, Yacoub MH. Cellular and molecular mechanisms of thoracic aortic aneurysms. Nat Rev Cardiol 2009;6: 771-786
3. Elefteriades JA, Farkas EA. Thoracic aortic aneurysm clinically pertinent controversies and uncertainties. J Am Coll Cardiol 2010;55:841-857
4. National Center for Injury Prevention and Control. WISQARS Leading Causes of Death Reports, 1999-2006. Available at:http://webappa.cdc.gov/sasweb/ncipc/ leadcaus10.html/
5. Zhu H, Belcher M, van der Harst P. Healthy aging and disease: Role for telomere biology? ClinSci (Lond) 2011;120:427-440
6. De Meyer T, Rietzschel ER, De Buyzere ML, Van Criekinge W, Bekaert S. Telomere length and cardiovascular aging: the means to the ends? Ageing Res Rev 2011;10:297-303
7. Epel ES, Merkin SS, Cawthon R, Blackburn EH, Adler NE, Pletcher MJ, Seeman TE. The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men. Aging (Albany NY) 2008;1:81-88
8. Mainous AG, Diaz VA. Telomere length as a risk marker for cardiovascular disease: The next big thing? Expert Rev Mol Diagn2010;10:969-971
9. Huzen J, de Boer RA, van Veldhuisen DJ, van Gilst WH, van der Harst P. The emerging role of telomere biology in cardiovascular disease. Front Biosci 2010;15:35-45
10. Saliques S, Zeller M, Lorin J, Lorgis L, Teyssier JR, Cottin Y, Rochette L, Vergely C. Telomere length and cardiovascular disease. Arch Cardiovasc Dis 2010;103:454-459
11. Fitzpatrick AL, Kronmal RA, Kimura M, Gardner JP, Psaty BM, Jenny NS, Tracy RP, Hardikar S, Aviv A. Leukocyte telomere length and mortality in the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci 2011; 66:421-429
12. Wilson WR, Herbert KE, Mistry Y, Stevens SE, Patel HR, Hastings RA, Thompson MM, Williams B. Blood leucocyte telomere DNA content predicts vascular telomere DNA content in humans with and without vascular disease. Eur Heart J 2008;29:2689-2694
13. Atturu G, Brouilette S, Samani NJ, London NJ, Sayers RD, Bown MJ. Short leukocyte telomere length is associated with abdominal aortic aneurysm (AAA). Eur J Vasc Endovasc Surg 2010;39:559-564
14. Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, et al. ACCF/AHA/AATS/ACR/ASA/SCA/ SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease: A report of the American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. J Am Coll Cardiol 2010;55: e27-e129
15. Licastro F, Candore G, Lio D, Porcellini E, Colonna-Romano G, Franceschi C, Caruso C. Innate immunity and inflammation in ageing: A key for understanding age-related diseases. Immun Ageing 2005;2:8
16. Candore G, Balistreri CR, Caruso M, Grimaldi MP, Incalcaterra E, Listì F, Vasto S, Caruso C. Pharmacogenomics: a tool to prevent and cure coronary heart disease. Curr Pharm Des 2007;13:3726-3734