Notch signal suppresses toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation

Journal of Biological Chemistry

Volumn 287, Issue 9, 2012, Pages 6208-6217

  Zhang, Qinghua ^a,b   Wang, Chunmei ^a   Liu, Zhaolong ^c   Liu, Xingguang ^a   Han, Chaofeng ^a   Cao, Xuetao ^a   Li, Nan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI OCEAN UNIVERSITY   (China)

^c People's Hospital of Pudong New Area   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORIES; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED KINASE; INFLAMMATORY RESPONSE; NEW MECHANISMS; NOTCH SIGNALING; NUCLEAR FACTORS; OVER-EXPRESSION; PROINFLAMMATORY CYTOKINES; SIGNALING PATHWAYS; TARGET GENES; TLR SIGNALING; TOLL-LIKE RECEPTORS; TRANSCRIPTION ACTIVITY;

GENES; MACROPHAGES; PATHOLOGY; PHOSPHORYLATION; PIGMENTS; TRANSCRIPTION;

SIGNALING;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELOID DIFFERENTIATION FACTOR 88; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; HES1 GENE; HES5 GENE; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CYTOKINES; HEK293 CELLS; HUMANS; INFLAMMATION; MACROPHAGES, PERITONEAL; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTORS; UP-REGULATION;

EID: 84863137323     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.310375     Document Type: Article

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