Notch signaling mediates crosstalk between endothelial cells and macrophages via Dll4 and IL6 in cardiac microvascular inflammation

Biochemical Pharmacology

Volumn 104, Issue , 2016, Pages 95-107

  Pabois, Angélique ^a,b,c   Pagie, Sylvain ^a,b,c   Gérard, Nathalie ^a,b   Laboisse, Christian ^b   Pattier, Sabine ^b   Hulin, Philippe ^c,d   Nedellec, Steven ^c,d   Toquet, Claire ^b   Charreau, Béatrice ^a,b,c  

^a Centre National de la Recherche Scientifique   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE NANTES   (France)

^d Recombinant Protein Production Facility Federative Research Structure François Bonamy   (France)

Author keywords

Cardiac transplant; Endothelial cells; Macrophage polarization; Notch signaling

Indexed keywords

CD11B ANTIGEN; CD200 RECEPTOR; CD40 ANTIGEN; CD64 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 6; LIGAND; NOTCH LIGAND DLL4; NOTCH RECEPTOR; NOTCH4 RECEPTOR; UNCLASSIFIED DRUG; DLL4 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADULT; ANTIBODY MEDIATED REJECTION; ARTICLE; CARDIOVASCULAR INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; FEMALE; HEART GRAFT; HEART MUSCLE BIOPSY; HUMAN; HUMAN CELL; INFLAMMATORY CELL; MACROPHAGE; MALE; MONOCYTE; POLARIZATION; PRIORITY JOURNAL; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION; ALLOGRAFT; CELL COMMUNICATION; COCULTURE; GRAFT REJECTION; HEART TRANSPLANTATION; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; MICROVASCULATURE; MONONUCLEAR CELL; VASCULARIZATION;

ALLOGRAFTS; CELL COMMUNICATION; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; GRAFT REJECTION; HEART TRANSPLANTATION; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MICROVESSELS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84959201358     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2016.01.016     Document Type: Article

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