Notch Activation Results in Phenotypic and Functional Changes Consistent with Endothelial-to-Mesenchymal Transformation

Circulation Research

Volumn 94, Issue 7, 2004, Pages 910-917

  Noseda, Michela ^a,b   McLean, Graeme ^a,b   Niessen, Kyle ^a,b   Chang, Linda ^a,b   Pollet, Ingrid ^a,b   Montpetit, Rachel ^b   Shahidi, Réza ^a   Dorovini Zis, Katerina ^a   Li, Linheng ^c   Beckstead, Benjamin ^d   Durand, Ralph E ^b   Hoodless, Pamela A ^b   Karsan, Aly ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d University of Washington   (United States)

Author keywords

Endocardial cushion; Endothelial to mesenchymal transformation; Jagged1; Notch

Indexed keywords

ALPHA ACTIN; ANGIOPOIETIN RECEPTOR; CADHERIN; CD31 ANTIGEN; FIBRONECTIN; NITRIC OXIDE SYNTHASE; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH4 RECEPTOR; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN; TIE 1 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MESENCHYME; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; UPREGULATION;

ACTINS; ANIMALS; ANTIGENS, CD; ANTIGENS, CD31; CADHERINS; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; CELL LINE; ENDOCARDIUM; ENDOTHELIUM, VASCULAR; FETAL HEART; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART SEPTUM; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MESODERM; MICE; MUSCLE, SMOOTH, VASCULAR; PHENOTYPE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BIOSYNTHESIS; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTOR, NOTCH1; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; RECOMBINANT FUSION PROTEINS; SHEEP; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

EID: 11144354703     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000124300.76171.C9     Document Type: Article

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