A beacon of hope in stroke therapy - Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies

Pharmacology and Therapeutics

Volumn 160, Issue , 2016, Pages 159-179

  Hoque, Ashfaqul ^a   Hossain, M Iqbal ^a   Ameen, S Sadia ^a   Ang, Ching Seng ^b   Williamson, Nicholas ^b   Ng, Dominic C H ^a,c   Chueh, Anderly C ^a,d   Roulston, Carli ^a   Cheng, Heung Chin ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Calpain; Excitotoxicity; Neuron death; NMDAR; nNOS; Stroke

Indexed keywords

CALPAIN; CELL PROTEIN; ION CHANNEL; IONOTROPIC RECEPTOR; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPROTECTIVE AGENT; PEPTIDE; TAT-NR2B9C;

BRAIN DAMAGE; CELL LOSS; CEREBROVASCULAR ACCIDENT; DRUG EFFICACY; EXCITOTOXICITY; HUMAN; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; CELL DEATH; DRUG EFFECTS; NERVE CELL; STROKE;

ANIMALS; CELL DEATH; HUMANS; MEMANTINE; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDES; SIGNAL TRANSDUCTION; STROKE;

EID: 84975743196     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2016.02.009     Document Type: Review

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