Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia

Journal of Neurochemistry

Volumn 102, Issue 5, 2007, Pages 1506-1517

  Shioda, Norifumi ^a   Han, Feng ^a   Moriguchi, Shigeki ^a   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Brain ischemia; Calcineurin; Calpain; Fas ligand; Forkhead transcription factor; Neuronal death

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; FAS LIGAND; FORKHEAD TRANSCRIPTION FACTOR; SERINE; TACROLIMUS; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REPERFUSION; STIMULATION; TRANSCRIPTION INITIATION; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN ISCHEMIA; CALCINEURIN; CELL DEATH; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; FAS LIGAND PROTEIN; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED C57BL; NFATC TRANSCRIPTION FACTORS; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; PROTEIN TRANSPORT; SERINE; TACROLIMUS;

GERBILLINAE;

EID: 34547916107     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04600.x     Document Type: Article

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