Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos)

Journal of Neurochemistry

Volumn 110, Issue 2, 2009, Pages 687-696

  Wang, Yingfei ^a   Kim, No S ^a   Li, Xiaoling ^a   Greer, Peter A ^b,c   Koehler, Raymond C ^a   Dawson, Valina L ^a   Dawson, Ted M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b QUEEN S UNIVERSITY   (Canada)

^c QUEEN S UNIVERSITY   (Canada)

Author keywords

Apoptosis inducing factor; Calpain; Parthanatos; Poly(ADP ribose) polymerase 1

Indexed keywords

3,4 DIHYDRO 5 [4 (1 PIPERIDINYL)BUTOXYL] 1(2H) ISOQUINOLINONE; APOPTOSIS INDUCING FACTOR; CALPAIN; CALPASTATIN; METHYLNITRONITROSOGUANIDINE; N METHYL DEXTRO ASPARTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE TRANSLOCATION; MALE; MITOCHONDRION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS INDUCING FACTOR; CALPAIN; CELL DEATH; CELLS, CULTURED; ENZYME ACTIVATION; MALE; MICE; MICE, INBRED C57BL; POLY(ADP-RIBOSE) POLYMERASES;

EID: 67649491430     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06167.x     Document Type: Article

References (32)

1. Andrabi S. A., Kim N. S., Yu S. W. et al. (2006) Poly(ADP-ribose) (PAR) polymer is a death signal. Proc. Natl Acad. Sci. USA 103, 18308 18313. (Pubitemid 44871654)
2. Andrabi S. A., Dawson T. M. Dawson V. L. (2008) Mitochondrial and nuclear cross talk in cell death: parthanatos. Ann. N Y Acad. Sci. 1147, 233 241.
3. Arthur J. S., Elce J. S., Hegadorn C., Williams K. Greer P. A. (2000) Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division. Mol. Cell. Biol. 20, 4474 4481. (Pubitemid 30346642)
4. Bevers M. B. Neumar R. W. (2008) Mechanistic role of calpains in postischemic neurodegeneration. J. Cereb. Blood Flow Metab. 28, 655 673.
5. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248 254.
6. Cao G., Xing J., Xiao X., Liou A. K., Gao Y., Yin X. M., Clark R. S., Graham S. H. Chen J. (2007) Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury. J. Neurosci. 27, 9278 9293. (Pubitemid 47358221)
7. Cosi C. Marien M. (1999) Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide. Ann. N Y Acad. Sci. 890, 227 239. (Pubitemid 30040381)
8. Cuerrier D., Moldoveanu T. Davies P. L. (2005) Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactions. J. Biol. Chem. 280, 40632 40641. (Pubitemid 41780554)
9. Culmsee C., Zhu C., Landshamer S., Becattini B., Wagner E., Pellecchia M., Blomgren K. Plesnila N. (2005) Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J. Neurosci. 25, 10262 10272. (Pubitemid 41636223)
10. David K. K., Andrabi S. A., Dawson T. M. Dawson V. L. (2009) Parthanatos, a messenger of death. Front Biosci. 14, 1116 1128.
11. Dawson V. L., Dawson T. M., Bartley D. A., Uhl G. R. Snyder S. H. (1993) Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13, 2651 2661. (Pubitemid 23151779)
12. Eliasson M. J., Sampei K., Mandir A. S. et al. (1997) Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat. Med. 3, 1089 1095. (Pubitemid 27444449)
13. Endres M., Wang Z. Q., Namura S., Waeber C. Moskowitz M. A. (1997) Ischemic brain injury is mediated by the activation of poly(ADP-ribose) polymerase. J. Cereb. Blood Flow Metab. 17, 1143 1151. (Pubitemid 27514738)
14. Mandir A. S., Przedborski S., Jackson-Lewis V., Wang Z. Q., Simbulan-Rosenthal C. M., Smulson M. E., Hoffman B. E., Guastella D. B., Dawson V. L. Dawson T. M. (1999) Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proc. Natl Acad. Sci. USA 96, 5774 5779. (Pubitemid 29234694)
15. Mandir A. S., Poitras M. F., Berliner A. R., Herring W. J., Guastella D. B., Feldman A., Poirier G. G., Wang Z. Q., Dawson T. M. Dawson V. L. (2000) NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase. J. Neurosci. 20, 8005 8011. (Pubitemid 30804650)
16. Meli E., Pangallo M., Picca R., Baronti R., Moroni F. Pellegrini-Giampietro D. E. (2004) Differential role of poly(ADP-ribose) polymerase-1in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro. Mol. Cell. Neurosci. 25, 172 180. (Pubitemid 38220873)
17. Moubarak R. S., Yuste V. J., Artus C., Bouharrour A., Greer P. A., Menissier-de Murcia J. Susin S. A. (2007) Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol. Cell. Biol. 27, 4844 4862. (Pubitemid 47016136)
18. Otera H., Ohsakaya S., Nagaura Z., Ishihara N. Mihara K. (2005) Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space. EMBO J. 24, 1375 1386. (Pubitemid 40593058)
19. Pacher P. Szabo C. (2008) Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease. Am. J. Pathol. 173, 2 13. (Pubitemid 351947950)
20. Plesnila N., Zhu C., Culmsee C., Groger M., Moskowitz M. A. Blomgren K. (2004) Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 24, 458 466. (Pubitemid 38452237)
21. Polster B. M., Basanez G., Etxebarria A., Hardwick J. M. Nicholls D. G. (2005) Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J. Biol. Chem. 280, 6447 6454. (Pubitemid 40341192)
22. Sattler R. Tymianski M. (2001) Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death. Mol. Neurobiol. 24, 107 129. (Pubitemid 34066681)
23. Susin S. A., Lorenzo H. K., Zamzami N. et al. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397, 441 446.
24. Szatkowski M. Attwell D. (1994) Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms. Trends Neurosci. 17, 359 365. (Pubitemid 24256070)
25. Tan Y., Dourdin N., Wu C., De Veyra T., Elce J. S. Greer P. A. (2006) Conditional disruption of ubiquitous calpains in the mouse. Genesis 44, 297 303.
26. Wang H., Yu S. W., Koh D. W., Lew J., Coombs C., Bowers W., Federoff H. J., Poirier G. G., Dawson T. M. Dawson V. L. (2004) Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. J. Neurosci. 24, 10963 10973. (Pubitemid 39602407)
27. Wang Y., Luo W. Reiser G. (2007) Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain. Biochem. J. 401, 65 78. (Pubitemid 46114600)
28. Wang S., Shan P., Song Z., Dai T., Wang R. Chi Z. (2008) Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus. Brain Res. Bull. 76, 90 96.
29. Wang Y., Dawson V. L. Dawson T. M. (2009) Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos. Exp. Neurol. In Press.
30. Yu S. W., Wang H., Poitras M. F., Coombs C., Bowers W. J., Federoff H. J., Poirier G. G., Dawson T. M. Dawson V. L. (2002) Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297, 259 263. (Pubitemid 34761289)
31. Yu S. W., Andrabi S. A., Wang H., Kim N. S., Poirier G. G., Dawson T. M. Dawson V. L. (2006) Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc. Natl Acad. Sci. USA 103, 18314 18319. (Pubitemid 44871655)
32. Zhang J., Dawson V. L., Dawson T. M. Snyder S. H. (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263, 687 689. (Pubitemid 24076297)