Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia

Journal of Neurochemistry

Volumn 98, Issue 1, 2006, Pages 310-320

  Shioda, Norifumi ^a   Moriguchi, Shigeki ^a,b   Shirasaki, Yasufumi ^b   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Brain ischemia; Calcineurin; Calmodulin; Calpain; Neuronal death; NFAT

Indexed keywords

CALCINEURIN A; CALCIUM ION; CALMODULIN; CALMODULIN INHIBITOR; CALPAIN; DOPAMINE REGULATED PHOSPHOPROTEIN 32; DY 9760 E; ISOENZYME; PHOSPHOPROTEIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN PERFUSION; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME SUBUNIT; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR WEIGHT; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN TRANSPORT; PYRAMIDAL NERVE CELL;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN ISCHEMIA; CALCINEURIN; CALPAIN; CARRIER PROTEINS; CASEINS; CELL DEATH; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MICE; MICE, INBRED C57BL; MICROFILAMENT PROTEINS; MOLECULAR WEIGHT; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORUS ISOTOPES; PROTEIN SUBUNITS; SUBCELLULAR FRACTIONS;

EID: 33745070887     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03874.x     Document Type: Article

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