The complex PrPc-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

Journal of Neuroscience

Volumn 32, Issue 47, 2012, Pages 16857-16871

  Larson, Megan ^a,b   Sherman, Mathew A ^a,b   Amar, Fatou ^a,b   Nuvolone, Mario ^c,d   Schneider, Julie A ^e   Bennett, David A ^e   Aguzzi, Adriano ^c   Lesné, Sylvain E ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d SCUOLA UNIVERSITARIA SUPERIORE IUSS PAVIA   (Italy)

^e RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CAVEOLIN 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NEURON SPECIFIC NUCLEAR PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; PRION PROTEIN; PROTEIN KINASE FYN; SYNAPTOPHYSIN; TAU PROTEIN;

AGED; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; FEMALE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATOGRAPHY, GEL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE DELETION; GENE DOSAGE; HUMANS; IMMUNOPRECIPITATION; MALE; MICE; MICE, TRANSGENIC; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FYN; PRPC PROTEINS; TAU PROTEINS;

EID: 84869992747     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1858-12.2012     Document Type: Article

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