메뉴 건너뛰기




Volumn 1, Issue 3, 2011, Pages 138-147

Safety of Thrombolysis in Acute Ischemic Stroke: A Review of Complications, Risk Factors, and Newer Technologies

Author keywords

safety; stroke; thrombolysis

Indexed keywords


EID: 84992816467     PISSN: 19418744     EISSN: 19418752     Source Type: Journal    
DOI: 10.1177/1941875211408731     Document Type: Review
Times cited : (165)

References (63)
  • 1
    • 0035942340 scopus 로고    scopus 로고
    • Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility
    • Barber PA Zhang J Demchuk AM Hill MD Buchan AM. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology. 2001; 56(8):1015–1020.
    • (2001) Neurology , vol.56 , Issue.8 , pp. 1015-1020
    • Barber, P.A.1    Zhang, J.2    Demchuk, A.M.3    Hill, M.D.4    Buchan, A.M.5
  • 2
    • 33646191849 scopus 로고    scopus 로고
    • IV tissue plasminogen activator use in acute stroke: experience from a statewide registry
    • Deng YZ Reeves MJ Jacobs BS, et al. IV tissue plasminogen activator use in acute stroke: experience from a statewide registry. Neurology. 2006; 66(3):306–312.
    • (2006) Neurology , vol.66 , Issue.3 , pp. 306-312
    • Deng, Y.Z.1    Reeves, M.J.2    Jacobs, B.S.3
  • 3
    • 68749100878 scopus 로고    scopus 로고
    • Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association
    • Del Zoppo GJ Saver JL Jauch EC Adams HP Jr. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke. 2009; 40(8):2945–2948.
    • (2009) Stroke , vol.40 , Issue.8 , pp. 2945-2948
    • Del Zoppo, G.J.1    Saver, J.L.2    Jauch, E.C.3    Adams, H.P.4
  • 4
    • 0035856413 scopus 로고    scopus 로고
    • Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial
    • Kase CS Furlan AJ Wechsler LR, et al. Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial. Neurology. 2001; 57(9):1603–1610.
    • (2001) Neurology , vol.57 , Issue.9 , pp. 1603-1610
    • Kase, C.S.1    Furlan, A.J.2    Wechsler, L.R.3
  • 5
    • 42449127584 scopus 로고    scopus 로고
    • Methodology of the Interventional Management of Stroke III Trial
    • Khatri P Hill MD Palesch YY, et al. Methodology of the Interventional Management of Stroke III Trial. Int J Stroke. 2008; 3(2):130–137.
    • (2008) Int J Stroke , vol.3 , Issue.2 , pp. 130-137
    • Khatri, P.1    Hill, M.D.2    Palesch, Y.Y.3
  • 6
    • 41149121206 scopus 로고    scopus 로고
    • Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial
    • Smith WS Sung G Saver J, et al. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke. 2008; 39(4):1205–1212.
    • (2008) Stroke , vol.39 , Issue.4 , pp. 1205-1212
    • Smith, W.S.1    Sung, G.2    Saver, J.3
  • 7
    • 68249091754 scopus 로고    scopus 로고
    • The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease
    • Penumbra pivotal stroke trial investigators. The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke. 2009; 40(8):2761–2768.
    • (2009) Stroke , vol.40 , Issue.8 , pp. 2761-2768
  • 8
    • 34548233214 scopus 로고    scopus 로고
    • Hemorrhage after thrombolytic therapy for stroke: the clinically relevant number needed to harm
    • Saver JL. Hemorrhage after thrombolytic therapy for stroke: the clinically relevant number needed to harm. Stroke. 2007; 38(8):2279–2283.
    • (2007) Stroke , vol.38 , Issue.8 , pp. 2279-2283
    • Saver, J.L.1
  • 9
    • 0343118114 scopus 로고    scopus 로고
    • Nov
    • Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group. Stroke. Nov 1997; 28(11):2109–2118.
    • (1997) Stroke , vol.28 , Issue.11 , pp. 2109-2118
  • 10
    • 52649165720 scopus 로고    scopus 로고
    • Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
    • Hacke W Kaste M Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008; 359(13):1317–1329.
    • (2008) N Engl J Med , vol.359 , Issue.13 , pp. 1317-1329
    • Hacke, W.1    Kaste, M.2    Bluhmki, E.3
  • 11
    • 0345599248 scopus 로고    scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke in clinical practice: a meta-analysis of safety data
    • Graham GD. Tissue plasminogen activator for acute ischemic stroke in clinical practice: a meta-analysis of safety data. Stroke. 2003; 34(12):2847–2850.
    • (2003) Stroke , vol.34 , Issue.12 , pp. 2847-2850
    • Graham, G.D.1
  • 12
    • 68249087149 scopus 로고    scopus 로고
    • Comparison of intravenous alteplase with a combined intravenous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): a prospective cohort study
    • Mazighi M Serfaty JM Labreuche J, et al. Comparison of intravenous alteplase with a combined intravenous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): a prospective cohort study. Lancet Neurol. 2009; 8(9):802–809.
    • (2009) Lancet Neurol , vol.8 , Issue.9 , pp. 802-809
    • Mazighi, M.1    Serfaty, J.M.2    Labreuche, J.3
  • 13
    • 21444458290 scopus 로고    scopus 로고
    • Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic stroke
    • Brown DL Barsan WG Lisabeth LD Gallery ME Morgenstern LB. Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic stroke. Ann Emerg Med. 2005; 46(1):56–60.
    • (2005) Ann Emerg Med , vol.46 , Issue.1 , pp. 56-60
    • Brown, D.L.1    Barsan, W.G.2    Lisabeth, L.D.3    Gallery, M.E.4    Morgenstern, L.B.5
  • 15
    • 0037046216 scopus 로고    scopus 로고
    • Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey
    • Tanne D Kasner SE Demchuk AM, et al. Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. Circulation. 2002; 105(14):1679–1685.
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1679-1685
    • Tanne, D.1    Kasner, S.E.2    Demchuk, A.M.3
  • 16
    • 27644516008 scopus 로고    scopus 로고
    • Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (> or =80 years) stroke patients
    • Berrouschot J Rother J Glahn J Kucinski T Fiehler J Thomalla G. Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (> or =80 years) stroke patients. Stroke. 2005; 36(11):2421–2425.
    • (2005) Stroke , vol.36 , Issue.11 , pp. 2421-2425
    • Berrouschot, J.1    Rother, J.2    Glahn, J.3    Kucinski, T.4    Fiehler, J.5    Thomalla, G.6
  • 17
    • 71849095831 scopus 로고    scopus 로고
    • Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial
    • Bluhmki E Chamorro A Davalos A, et al. Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial. Lancet Neurol. 2009; 8(12):1095–1102.
    • (2009) Lancet Neurol , vol.8 , Issue.12 , pp. 1095-1102
    • Bluhmki, E.1    Chamorro, A.2    Davalos, A.3
  • 18
    • 58149357100 scopus 로고    scopus 로고
    • Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST)
    • Wahlgren N Ahmed N Eriksson N, et al. Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST). Stroke. 2008; 39(12):3316–3322.
    • (2008) Stroke , vol.39 , Issue.12 , pp. 3316-3322
    • Wahlgren, N.1    Ahmed, N.2    Eriksson, N.3
  • 19
    • 70349243755 scopus 로고    scopus 로고
    • Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke: pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II Trials
    • Cucchiara B Kasner SE Tanne D, et al. Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke: pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II Trials. Stroke. 2009; 40(9):3067–3072.
    • (2009) Stroke , vol.40 , Issue.9 , pp. 3067-3072
    • Cucchiara, B.1    Kasner, S.E.2    Tanne, D.3
  • 20
    • 77951731600 scopus 로고    scopus 로고
    • Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia
    • Chernyshev OY Martin-Schild S Albright KC, et al. Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia. Neurology. 2010; 74(17):1340–1345.
    • (2010) Neurology , vol.74 , Issue.17 , pp. 1340-1345
    • Chernyshev, O.Y.1    Martin-Schild, S.2    Albright, K.C.3
  • 21
    • 0032930284 scopus 로고    scopus 로고
    • Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke
    • Demchuk AM Morgenstern LB Krieger DW, et al. Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke. Stroke. 1999; 30(1):34–39.
    • (1999) Stroke , vol.30 , Issue.1 , pp. 34-39
    • Demchuk, A.M.1    Morgenstern, L.B.2    Krieger, D.W.3
  • 22
    • 34347397407 scopus 로고    scopus 로고
    • Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors
    • Lansberg MG Albers GW Wijman CA. Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors. Cerebrovasc Dis. 2007; 24(1):1–10.
    • (2007) Cerebrovasc Dis , vol.24 , Issue.1 , pp. 1-10
    • Lansberg, M.G.1    Albers, G.W.2    Wijman, C.A.3
  • 23
    • 15744379732 scopus 로고    scopus 로고
    • Significance of elevated blood pressure and its management on the short-term outcome of patients with acute ischemic stroke
    • Rodriguez-Garcia JL Botia E de La Sierra A Villanueva MA Gonzalez-Spinola J. Significance of elevated blood pressure and its management on the short-term outcome of patients with acute ischemic stroke. Am J Hypertens. 2005; 18(3):379–384.
    • (2005) Am J Hypertens , vol.18 , Issue.3 , pp. 379-384
    • Rodriguez-Garcia, J.L.1    Botia, E.2    de La Sierra, A.3    Villanueva, M.A.4    Gonzalez-Spinola, J.5
  • 24
    • 0028783948 scopus 로고
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
    • Dec 14
    • Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. Dec 14 1995; 333(24):1581–1587.
    • (1995) N Engl J Med , vol.333 , Issue.24 , pp. 1581-1587
  • 25
    • 70350524024 scopus 로고    scopus 로고
    • Pre-tissue plasminogen activator blood pressure levels and risk of symptomatic intracerebral hemorrhage
    • Nov
    • Tsivgoulis G Frey JL Flaster M, et al. Pre-tissue plasminogen activator blood pressure levels and risk of symptomatic intracerebral hemorrhage. Stroke. Nov 2009; 40(11):3631–3634.
    • (2009) Stroke , vol.40 , Issue.11 , pp. 3631-3634
    • Tsivgoulis, G.1    Frey, J.L.2    Flaster, M.3
  • 26
    • 19944413300 scopus 로고    scopus 로고
    • Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator
    • Jan
    • Derex L Hermier M Adeleine P, et al. Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator. J Neurol Neurosurg Psychiatry. Jan 2005; 76(1):70–75.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , Issue.1 , pp. 70-75
    • Derex, L.1    Hermier, M.2    Adeleine, P.3
  • 27
    • 74549186438 scopus 로고    scopus 로고
    • Influence of antiplatelet pre-treatment on the risk of intracranial haemorrhage in acute ischaemic stroke after intravenous thrombolysis
    • Feb
    • Dorado L Millan M de la Ossa NP, et al. Influence of antiplatelet pre-treatment on the risk of intracranial haemorrhage in acute ischaemic stroke after intravenous thrombolysis. Eur J Neurol. Feb; 17(2):301–306.
    • Eur J Neurol , vol.17 , Issue.2 , pp. 301-306
    • Dorado, L.1    Millan, M.2    de la Ossa, N.P.3
  • 28
    • 70349480935 scopus 로고    scopus 로고
    • Pre admission antithrombotics are associated with improved outcomes following ischaemic stroke: a cohort from the Registry of the Canadian Stroke Network
    • Oct
    • Dowlatshahi D Hakim A Fang J Sharma M. Pre admission antithrombotics are associated with improved outcomes following ischaemic stroke: a cohort from the Registry of the Canadian Stroke Network. Int J Stroke. Oct 2009; 4(5):328–334.
    • (2009) Int J Stroke , vol.4 , Issue.5 , pp. 328-334
    • Dowlatshahi, D.1    Hakim, A.2    Fang, J.3    Sharma, M.4
  • 29
    • 67849130410 scopus 로고    scopus 로고
    • Combined anti-platelet therapy with aspirin and clopidogrel: risk factor for thrombolysis-related intracerebral hemorrhage in acute ischemic stroke?
    • Sep 15
    • Hermann A Dzialowski I Koch R Gahn G. Combined anti-platelet therapy with aspirin and clopidogrel: risk factor for thrombolysis-related intracerebral hemorrhage in acute ischemic stroke? J Neurol Sci. Sep 15 2009; 284 (1-2): 155–157.
    • (2009) J Neurol Sci , vol.284 , Issue.1-2 , pp. 155-157
    • Hermann, A.1    Dzialowski, I.2    Koch, R.3    Gahn, G.4
  • 30
    • 0035852125 scopus 로고    scopus 로고
    • Lack of clinical significance of early ischemic changes on computed tomography in acute stroke
    • Dec 12
    • Patel SC Levine SR Tilley BC, et al. Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. JAMA. Dec 12 2001; 286(22):2830–2838.
    • (2001) JAMA , vol.286 , Issue.22 , pp. 2830-2838
    • Patel, S.C.1    Levine, S.R.2    Tilley, B.C.3
  • 31
    • 26044479507 scopus 로고    scopus 로고
    • Importance of early ischemic computed tomography changes using ASPECTS in NINDS rtPA Stroke Study
    • Oct
    • Demchuk AM Hill MD Barber PA Silver B Patel SC Levine SR. Importance of early ischemic computed tomography changes using ASPECTS in NINDS rtPA Stroke Study. Stroke. Oct 2005; 36(10):2110–2115.
    • (2005) Stroke , vol.36 , Issue.10 , pp. 2110-2115
    • Demchuk, A.M.1    Hill, M.D.2    Barber, P.A.3    Silver, B.4    Patel, S.C.5    Levine, S.R.6
  • 32
    • 0034642165 scopus 로고    scopus 로고
    • Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study
    • Dec 12
    • Marler JR Tilley BC Lu M, et al. Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study. Neurology. Dec 12 2000; 55(11):1649–1655.
    • (2000) Neurology , vol.55 , Issue.11 , pp. 1649-1655
    • Marler, J.R.1    Tilley, B.C.2    Lu, M.3
  • 34
    • 84906813873 scopus 로고    scopus 로고
    • Safety of Thrombolysis in Patients with Acute Ischemic Stroke Caused by Cervical Artery Dissection-A Review
    • Zinkstok S Nederkoorn P Vergouwen M. Safety of Thrombolysis in Patients with Acute Ischemic Stroke Caused by Cervical Artery Dissection-A Review. European Neurological Journal. 2010; 2(1):65–72.
    • (2010) European Neurological Journal , vol.2 , Issue.1 , pp. 65-72
    • Zinkstok, S.1    Nederkoorn, P.2    Vergouwen, M.3
  • 35
    • 77952469181 scopus 로고    scopus 로고
    • Luijckx GJ. tPA treatment for acute ischaemic stroke in patients with leukoaraiosis
    • Jun 1
    • Aries MJ Uyttenboogaart M Vroomen PC De Keyser J, Luijckx GJ. tPA treatment for acute ischaemic stroke in patients with leukoaraiosis. Eur J Neurol. Jun 1; 17(6):866–870.
    • Eur J Neurol , vol.17 , Issue.6 , pp. 866-870
    • Aries, M.J.1    Uyttenboogaart, M.2    Vroomen, P.C.3    De Keyser, J.4
  • 36
    • 34147124515 scopus 로고    scopus 로고
    • Leukoaraiosis and intracerebral hemorrhage after thrombolysis in acute stroke
    • Mar 27
    • Palumbo V Boulanger JM Hill MD Inzitari D Buchan AM. Leukoaraiosis and intracerebral hemorrhage after thrombolysis in acute stroke. Neurology. Mar 27 2007; 68(13):1020–1024.
    • (2007) Neurology , vol.68 , Issue.13 , pp. 1020-1024
    • Palumbo, V.1    Boulanger, J.M.2    Hill, M.D.3    Inzitari, D.4    Buchan, A.M.5
  • 37
    • 49949111534 scopus 로고    scopus 로고
    • Importance of leukoaraiosis on CT for tissue plasminogen activator decision making: evaluation of the NINDS rt-PA Stroke Study
    • Demchuk AM Khan F Hill MD, et al. Importance of leukoaraiosis on CT for tissue plasminogen activator decision making: evaluation of the NINDS rt-PA Stroke Study. Cerebrovasc Dis. 2008; 26(2):120–125.
    • (2008) Cerebrovasc Dis , vol.26 , Issue.2 , pp. 120-125
    • Demchuk, A.M.1    Khan, F.2    Hill, M.D.3
  • 38
    • 34249785974 scopus 로고    scopus 로고
    • Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group
    • Jun
    • Broderick J Connolly S Feldmann E, et al. Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group. Stroke. Jun 2007; 38(6):2001–2023.
    • (2007) Stroke , vol.38 , Issue.6 , pp. 2001-2023
    • Broderick, J.1    Connolly, S.2    Feldmann, E.3
  • 39
    • 77956418271 scopus 로고    scopus 로고
    • Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association
    • Sep
    • Morgenstern LB Hemphill JC 3rd Anderson C, et al. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. Sep; 41(9):2108–2129.
    • Stroke , vol.41 , Issue.9 , pp. 2108-2129
    • Morgenstern, L.B.1    Hemphill, J.C.2    Anderson, C.3
  • 40
    • 0034161354 scopus 로고    scopus 로고
    • Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS) study
    • Mar 1
    • Albers GW Bates VE Clark WM Bell R Verro P Hamilton SA. Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS) study. JAMA. Mar 1 2000; 283(9):1145–1150.
    • (2000) JAMA , vol.283 , Issue.9 , pp. 1145-1150
    • Albers, G.W.1    Bates, V.E.2    Clark, W.M.3    Bell, R.4    Verro, P.5    Hamilton, S.A.6
  • 41
    • 0035152260 scopus 로고    scopus 로고
    • Protocol violations in community-based rTPA stroke treatment are associated with symptomatic intracerebral hemorrhage
    • Jan
    • Lopez-Yunez AM Bruno A Williams LS Yilmaz E Zurru C Biller J. Protocol violations in community-based rTPA stroke treatment are associated with symptomatic intracerebral hemorrhage. Stroke. Jan 2001; 32(1):12–16.
    • (2001) Stroke , vol.32 , Issue.1 , pp. 12-16
    • Lopez-Yunez, A.M.1    Bruno, A.2    Williams, L.S.3    Yilmaz, E.4    Zurru, C.5    Biller, J.6
  • 42
    • 34247844511 scopus 로고    scopus 로고
    • Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
    • May
    • Adams HP Jr. del Zoppo G Alberts MJ, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke. May 2007; 38(5):1655–1711.
    • (2007) Stroke , vol.38 , Issue.5 , pp. 1655-1711
    • Adams, H.P.1    del Zoppo, G.2    Alberts, M.J.3
  • 43
    • 33846592841 scopus 로고    scopus 로고
    • Hemorrhagic complications after off-label thrombolysis for ischemic stroke
    • Feb
    • Aleu A Mellado P Lichy C Kohrmann M Schellinger PD. Hemorrhagic complications after off-label thrombolysis for ischemic stroke. Stroke. Feb 2007; 38(2):417–422.
    • (2007) Stroke , vol.38 , Issue.2 , pp. 417-422
    • Aleu, A.1    Mellado, P.2    Lichy, C.3    Kohrmann, M.4    Schellinger, P.D.5
  • 44
    • 84992890756 scopus 로고    scopus 로고
    • Detection and Significance of Incidental Unruptured Cerebral Aneurysms in Patients Undergoing Intravenous Thrombolysis for Acute Ischemic Stroke
    • Dec 9
    • Kim JT Park MS Yoon W Cho KH. Detection and Significance of Incidental Unruptured Cerebral Aneurysms in Patients Undergoing Intravenous Thrombolysis for Acute Ischemic Stroke. J Neuroimaging. Dec 9.
    • J Neuroimaging
    • Kim, J.T.1    Park, M.S.2    Yoon, W.3    Cho, K.H.4
  • 45
    • 78649470137 scopus 로고    scopus 로고
    • Safety of intravenous thrombolytic use in four emergency departments without acute stroke teams
    • Oct
    • Scott PA Frederiksen SM Kalbfleisch JD, et al. Safety of intravenous thrombolytic use in four emergency departments without acute stroke teams. Acad Emerg Med. Oct; 17(10):1062–1071.
    • Acad Emerg Med , vol.17 , Issue.10 , pp. 1062-1071
    • Scott, P.A.1    Frederiksen, S.M.2    Kalbfleisch, J.D.3
  • 46
    • 77957126877 scopus 로고    scopus 로고
    • Intravenous thrombolysis with recombinant tissue plasminogen activator in a stroke patient treated with dabigatran
    • De Smedt A De Raedt S Nieboer K De Keyser J Brouns R. Intravenous thrombolysis with recombinant tissue plasminogen activator in a stroke patient treated with dabigatran. Cerebrovasc Dis. 2010; 30(5):533–534.
    • (2010) Cerebrovasc Dis , vol.30 , Issue.5 , pp. 533-534
    • De Smedt, A.1    De Raedt, S.2    Nieboer, K.3    De Keyser, J.4    Brouns, R.5
  • 47
    • 77449112420 scopus 로고    scopus 로고
    • Assessment and improvement of figures to visually convey benefit and risk of stroke thrombolysis
    • Feb
    • Gadhia J Starkman S Ovbiagele B Ali L Liebeskind D Saver JL, Assessment and improvement of figures to visually convey benefit and risk of stroke thrombolysis. Stroke. Feb; 41(2):300–306.
    • Stroke , vol.41 , Issue.2 , pp. 300-306
    • Gadhia, J.1    Starkman, S.2    Ovbiagele, B.3    Ali, L.4    Liebeskind, D.5    Saver, J.L.6
  • 48
    • 58149218839 scopus 로고    scopus 로고
    • The HAT Score: a simple grading scale for predicting hemorrhage after thrombolysis
    • Oct 28
    • Lou M Safdar A Mehdiratta M, et al. The HAT Score: a simple grading scale for predicting hemorrhage after thrombolysis. Neurology. Oct 28 2008; 71(18):1417–1423.
    • (2008) Neurology , vol.71 , Issue.18 , pp. 1417-1423
    • Lou, M.1    Safdar, A.2    Mehdiratta, M.3
  • 49
    • 33845411557 scopus 로고    scopus 로고
    • The stroke-thrombolytic predictive instrument: a predictive instrument for intravenous thrombolysis in acute ischemic stroke
    • Dec
    • Kent DM Selker HP Ruthazer R Bluhmki E Hacke W. The stroke-thrombolytic predictive instrument: a predictive instrument for intravenous thrombolysis in acute ischemic stroke. Stroke. Dec 2006; 37(12):2957–2962.
    • (2006) Stroke , vol.37 , Issue.12 , pp. 2957-2962
    • Kent, D.M.1    Selker, H.P.2    Ruthazer, R.3    Bluhmki, E.4    Hacke, W.5
  • 50
    • 0033837325 scopus 로고    scopus 로고
    • Orolingual angioneurotic edema following therapy of acute ischemic stroke with alteplase
    • Aug 22
    • Rudolf J Grond M Schmulling S Neveling M Heiss W. Orolingual angioneurotic edema following therapy of acute ischemic stroke with alteplase. Neurology. Aug 22 2000; 55(4):599–600.
    • (2000) Neurology , vol.55 , Issue.4 , pp. 599-600
    • Rudolf, J.1    Grond, M.2    Schmulling, S.3    Neveling, M.4    Heiss, W.5
  • 51
    • 0037988721 scopus 로고    scopus 로고
    • Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke
    • May 13
    • Hill MD Lye T Moss H, et al. Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke. Neurology. May 13 2003; 60(9):1525–1527.
    • (2003) Neurology , vol.60 , Issue.9 , pp. 1525-1527
    • Hill, M.D.1    Lye, T.2    Moss, H.3
  • 52
    • 0035846535 scopus 로고    scopus 로고
    • Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans
    • Kidwell CS Saver JL Mattiello J, et al. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 2001; 57(11):2015–2021.
    • (2001) Neurology , vol.57 , Issue.11 , pp. 2015-2021
    • Kidwell, C.S.1    Saver, J.L.2    Mattiello, J.3
  • 53
    • 67650079313 scopus 로고    scopus 로고
    • A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association
    • Jul
    • Schwamm LH Holloway RG Amarenco P, et al. A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke. Jul 2009; 40(7):2616–2634.
    • (2009) Stroke , vol.40 , Issue.7 , pp. 2616-2634
    • Schwamm, L.H.1    Holloway, R.G.2    Amarenco, P.3
  • 54
    • 48849098929 scopus 로고    scopus 로고
    • Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study
    • Sep
    • Meyer BC Raman R Hemmen T, et al. Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study. Lancet Neurol. Sep 2008; 7(9):787–795.
    • (2008) Lancet Neurol , vol.7 , Issue.9 , pp. 787-795
    • Meyer, B.C.1    Raman, R.2    Hemmen, T.3
  • 55
    • 77954749308 scopus 로고    scopus 로고
    • Evidence-based guideline: The role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    • Schellinger PD Bryan RN Caplan LR, et al. Evidence-based guideline: The role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2010; 75(2):177–185.
    • (2010) Neurology , vol.75 , Issue.2 , pp. 177-185
    • Schellinger, P.D.1    Bryan, R.N.2    Caplan, L.R.3
  • 56
    • 34447515976 scopus 로고    scopus 로고
    • Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients
    • Jun
    • Tan JC Dillon WP Liu S Adler F Smith WS Wintermark M. Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients. Ann Neurol. Jun 2007; 61(6):533–543.
    • (2007) Ann Neurol , vol.61 , Issue.6 , pp. 533-543
    • Tan, J.C.1    Dillon, W.P.2    Liu, S.3    Adler, F.4    Smith, W.S.5    Wintermark, M.6
  • 57
    • 40949161352 scopus 로고    scopus 로고
    • Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial
    • Davis S Donnan G Parsons M, et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet neurology. 2008; 7(4):299–309.
    • (2008) Lancet neurology , vol.7 , Issue.4 , pp. 299-309
    • Davis, S.1    Donnan, G.2    Parsons, M.3
  • 58
    • 33845298309 scopus 로고    scopus 로고
    • Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study
    • Albers G Thijs V Wechsler L, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Annals of neurology. 2006; 60(5):508–517.
    • (2006) Annals of neurology , vol.60 , Issue.5 , pp. 508-517
    • Albers, G.1    Thijs, V.2    Wechsler, L.3
  • 59
    • 19944426190 scopus 로고    scopus 로고
    • The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase
    • Jan
    • Hacke W Albers G Al-Rawi Y, et al. The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke. Jan 2005; 36(1):66–73.
    • (2005) Stroke , vol.36 , Issue.1 , pp. 66-73
    • Hacke, W.1    Albers, G.2    Al-Rawi, Y.3
  • 60
    • 33646705400 scopus 로고    scopus 로고
    • Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset
    • May
    • Furlan AJ Eyding D Albers GW, et al. Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset. Stroke. May 2006; 37(5):1227–1231.
    • (2006) Stroke , vol.37 , Issue.5 , pp. 1227-1231
    • Furlan, A.J.1    Eyding, D.2    Albers, G.W.3
  • 61
    • 58249134578 scopus 로고    scopus 로고
    • Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study
    • Feb
    • Hacke W Furlan AJ Al-Rawi Y, et al. Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study. Lancet Neurol. Feb 2009; 8(2):141–150.
    • (2009) Lancet Neurol , vol.8 , Issue.2 , pp. 141-150
    • Hacke, W.1    Furlan, A.J.2    Al-Rawi, Y.3
  • 62
    • 62449139473 scopus 로고    scopus 로고
    • Thrombolytic therapy for patients who wake-up with stroke
    • Mar
    • Barreto AD Martin-Schild S Hallevi H, et al. Thrombolytic therapy for patients who wake-up with stroke. Stroke. Mar 2009; 40(3):827–832.
    • (2009) Stroke , vol.40 , Issue.3 , pp. 827-832
    • Barreto, A.D.1    Martin-Schild, S.2    Hallevi, H.3
  • 63
    • 84992882468 scopus 로고    scopus 로고
    • Reperfusion Therapy in Acute Ischemic Stroke with Unclear Onset by MRI Evaluation (RESTORE)
    • Kang D-W Sohn S-I Yu K-H, et al. Reperfusion Therapy in Acute Ischemic Stroke with Unclear Onset by MRI Evaluation (RESTORE). Stroke. 2011; 42(3):e110.
    • (2011) Stroke , vol.42 , Issue.3 , pp. e110
    • Kang, D.-W.1    Sohn, S.-I.2    Yu, K.-H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.