Protein S-Nitrosylation as a Therapeutic Target for Neurodegenerative Diseases

Trends in Pharmacological Sciences

Volumn 37, Issue 1, 2016, Pages 73-84

  Nakamura, Tomohiro ^a   Lipton, Stuart A ^a,b  

^a SCINTILLON INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; denitrosylation; NitroMemantine; Parkinson's disease; protein S nitrosylation; transnitrosylation

Indexed keywords

ALPHA TOCOPHEROL; CASPASE 3; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GUANYLATE CYCLASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MEMANTINE; N 6022; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OMIGAPIL; OXIDOREDUCTASE INHIBITOR; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; S NITROSOTHIOL;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CELL SURVIVAL; DEGENERATIVE DISEASE; DRUG EFFICACY; DRUG SAFETY; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUNTINGTON CHOREA; NERVE CELL LESION; NEUROPATHOLOGY; NEUROPROTECTION; NITROSATIVE STRESS; NITROSYLATION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PROCESSING; REVIEW; METABOLISM; NITROSATION; SECOND MESSENGER;

GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; NEURODEGENERATIVE DISEASES; NITRIC OXIDE; NITROSATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE NITROGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE; S-NITROSOTHIOLS; SECOND MESSENGER SYSTEMS;

EID: 84951335518     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2015.10.002     Document Type: Review

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