A selective phenelzine analogue inhibitor of histone demethylase LSD1

ACS Chemical Biology

Volumn 9, Issue 6, 2014, Pages 1284-1293

  Prusevich, Polina ^a   Kalin, Jay H ^a   Ming, Shonoi A ^a   Basso, Manuela ^c,f   Givens, Jeffrey ^d   Li, Xin ^a   Hu, Jianfei ^a   Taylor, Martin S ^a   Cieniewicz, Anne M ^a   Hsiao, Po Yuan ^a   Huang, Rong ^a,g   Roberson, Heather ^a   Adejola, Nkosi ^a   Avery, Lindsay B ^a   Casero, Robert A ^b   Taverna, Sean D ^a   Qian, Jiang ^a   Tackett, Alan J ^d   Ratan, Rajiv R ^c   McDonald, Oliver G ^e   Feinberg, Andrew P ^a   Cole, Philip A ^a   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^f UNIVERSITY OF TRENTO   (Italy)

^g VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AZACITIDINE; ENTINOSTAT; HISTONE DEACETYLASE INHIBITOR; HISTONE DEMETHYLASE; LYSINE SPECIFIC DEMETHYLASE 1; MOCETINOSTAT; NEUROPROTECTIVE AGENT; PANOBINOSTAT; PHENELZINE; SELEGILINE; UNCLASSIFIED DRUG; VORINOSTAT; AMINE OXIDASE (FLAVIN CONTAINING); ENZYME INHIBITOR; HISTONE; KDM1A PROTEIN, HUMAN; MONOAMINE OXIDASE A, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL PROLIFERATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DRUG SYNTHESIS; HISTONE METHYLATION; HISTONE PHOSPHORYLATION; HYDROGEN BOND; IC 50; IN VITRO STUDY; LUNG CANCER; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; RAT; STEADY STATE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DNA METHYLATION; DRUG EFFECTS; ENZYMOLOGY; FETUS; HUMAN; MAMMALIAN EMBRYO; METABOLISM; NERVE CELL; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; DNA METHYLATION; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; FETUS; HISTONE DEMETHYLASES; HISTONES; HUMANS; MONOAMINE OXIDASE; NEURONS; PHENELZINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84903205107     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500018s     Document Type: Article

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