Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

Nature Neuroscience

Volumn 5, Issue 5, 2002, Pages 405-414

  Hardingham, Giles E ^a   Fukunaga, Yuko ^a,b   Bading, Hilmar ^a,c  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b RIKEN HARIMA INSTITUTE   (Japan)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CHANNEL L TYPE; CALCIUM ION; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL DEATH; CELL LOSS; CELL SURVIVAL; GENE EXPRESSION REGULATION; HYPOXIA; ISCHEMIA; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NERVE CELL; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STROKE; SYNAPSE;

BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL DEATH; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GLUTAMIC ACID; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; NEURONS; PIPERIDINES; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 0036241207     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn835     Document Type: Article

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