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Volumn 8, Issue 6, 2016, Pages

Bone morphogenetic proteins

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DNA BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; SMAD PROTEIN; TRANSACTIVATOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84973141684     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a021899     Document Type: Article
Times cited : (379)

References (224)
  • 2
    • 77953590859 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in breast cancer: Dual role in tumourigenesis?
    • Alarmo EL, Kallioniemi A. 2010. Bone morphogenetic proteins in breast cancer: Dual role in tumourigenesis? Endocr Relat Cancer 17: 123-139.
    • (2010) Endocr Relat Cancer , vol.17 , pp. 123-139
    • Alarmo, E.L.1    Kallioniemi, A.2
  • 3
    • 38849140207 scopus 로고    scopus 로고
    • Bone morphogenetic protein 7 expression associates with bone metastasis in breast carcinomas
    • Alarmo EL, Korhonen T, Kuukasjärvi T, Huhtala H, Holli K, Kallioniemi A. 2008. Bone morphogenetic protein 7 expression associates with bone metastasis in breast carcinomas. Ann Oncol 19: 308-314.
    • (2008) Ann Oncol , vol.19 , pp. 308-314
    • Alarmo, E.L.1    Korhonen, T.2    Kuukasjärvi, T.3    Huhtala, H.4    Holli, K.5    Kallioniemi, A.6
  • 5
    • 0030056920 scopus 로고    scopus 로고
    • Human osteogenic protein-1 induces chondrogenic, osteoblastic, and/ or adipogenic differentiation of clonal murine target cells
    • Asahina I, Sampath TK, Haushka PV. 1996. Human osteogenic protein-1 induces chondrogenic, osteoblastic, and/ or adipogenic differentiation of clonal murine target cells. Exp Cell Res 222: 38-47.
    • (1996) Exp Cell Res , vol.222 , pp. 38-47
    • Asahina, I.1    Sampath, T.K.2    Haushka, P.V.3
  • 8
    • 0031760438 scopus 로고    scopus 로고
    • Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2)
    • Bächner D, Ahrens M, Schröder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohé L, Gross G. 1998. Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn 213: 398-411.
    • (1998) Dev Dyn , vol.213 , pp. 398-411
    • Bächner, D.1    Ahrens, M.2    Schröder, D.3    Hoffmann, A.4    Lauber, J.5    Betat, N.6    Steinert, P.7    Flohé, L.8    Gross, G.9
  • 9
    • 35648995949 scopus 로고    scopus 로고
    • Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins
    • Bailey JM, Singh PK, Hollingsworth MA. 2007. Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins. J Cell Biochem 102: 829-839.
    • (2007) J Cell Biochem , vol.102 , pp. 829-839
    • Bailey, J.M.1    Singh, P.K.2    Hollingsworth, M.A.3
  • 12
    • 77957255073 scopus 로고    scopus 로고
    • Dorsomorphin and LDN-193189 inhibitBMP-mediated Smad, p38 and Akt signaling in C2C12 cells
    • Boergermann JH, Kopf J, Yu PB, Knaus P. 2010. Dorsomorphin and LDN-193189 inhibitBMP-mediated Smad, p38 and Akt signaling in C2C12 cells. Int J Biochem Cell Biol 42: 1802-1807.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1802-1807
    • Boergermann, J.H.1    Kopf, J.2    Yu, P.B.3    Knaus, P.4
  • 13
    • 84901758151 scopus 로고    scopus 로고
    • The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
    • Boroviak T, Loos R, Bertone P, Smith A, Nichols J. 2014. The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol 16: 516-528.
    • (2014) Nat Cell Biol , vol.16 , pp. 516-528
    • Boroviak, T.1    Loos, R.2    Bertone, P.3    Smith, A.4    Nichols, J.5
  • 18
    • 0032577276 scopus 로고    scopus 로고
    • Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton
    • Brunet LJ, McMahon JA, McMahon AP, Harland RM. 1998. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science 280: 1455-1457.
    • (1998) Science , vol.280 , pp. 1455-1457
    • Brunet, L.J.1    McMahon, J.A.2    McMahon, A.P.3    Harland, R.M.4
  • 22
    • 0025672641 scopus 로고
    • Identification of transforming growth factor b family members present in boneinductive protein purified from bovine bone
    • Celeste AJ, Iannazzi JA, Taylor RC, Hewick RM, Rosen V, Wang EA, Wozney JM. 1990. Identification of transforming growth factor b family members present in boneinductive protein purified from bovine bone. Proc Natl Acad Sci 87: 9843-9847.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Iannazzi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5    Wang, E.A.6    Wozney, J.M.7
  • 23
    • 0032514135 scopus 로고    scopus 로고
    • Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages
    • Chen D, Ji X, Harris MA, Feng JQ, Karsenty G, Celeste AJ, Rosen V, Mundy GR, Harris SE. 1998. Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages. J Cell Biol 142: 295-305.
    • (1998) J Cell Biol , vol.142 , pp. 295-305
    • Chen, D.1    Ji, X.2    Harris, M.A.3    Feng, J.Q.4    Karsenty, G.5    Celeste, A.J.6    Rosen, V.7    Mundy, G.R.8    Harris, S.E.9
  • 24
    • 78650881444 scopus 로고    scopus 로고
    • BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone
    • Chen J, Liu J, Yang J, Chen Y, Chen J, Ni S, Song H, Zeng L, Ding K, Pei D. 2011. BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone. Cell Res 21: 205-212.
    • (2011) Cell Res , vol.21 , pp. 205-212
    • Chen, J.1    Liu, J.2    Yang, J.3    Chen, Y.4    Chen, J.5    Ni, S.6    Song, H.7    Zeng, L.8    Ding, K.9    Pei, D.10
  • 29
    • 33847369980 scopus 로고    scopus 로고
    • Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
    • David L, Mallet C, Mazerbourg S, Feige JJ, Bailly S. 2007. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 109: 1953-1961.
    • (2007) Blood , vol.109 , pp. 1953-1961
    • David, L.1    Mallet, C.2    Mazerbourg, S.3    Feige, J.J.4    Bailly, S.5
  • 31
    • 67449146883 scopus 로고    scopus 로고
    • Emerging role of bone morphogenetic proteins in angiogenesis
    • David L, Feige JJ, Bailly S. 2009. Emerging role of bone morphogenetic proteins in angiogenesis. Cytokine Growth Factor Rev 20: 203-212.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 203-212
    • David, L.1    Feige, J.J.2    Bailly, S.3
  • 34
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smadindependent pathways in TGF-β family signalling
    • Derynck R, Zhang YE. 2003. Smad-dependent and Smadindependent pathways in TGF-β family signalling. Nature 425: 577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 35
    • 33751161268 scopus 로고    scopus 로고
    • The cellular basis of kidney development
    • Dressler GR. 2006. The cellular basis of kidney development. Annu Rev Cell Dev Biol 22: 509-529.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 509-529
    • Dressler, G.R.1
  • 36
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. 1997. Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89: 747-754.
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 37
    • 0028832707 scopus 로고
    • A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
    • Dudley AT, Lyons KM, Robertson EJ. 1995. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev 9: 2795-2807.
    • (1995) Genes Dev , vol.9 , pp. 2795-2807
    • Dudley, A.T.1    Lyons, K.M.2    Robertson, E.J.3
  • 39
    • 84879426981 scopus 로고    scopus 로고
    • Bidirectional roles of bone morphogenetic proteins in cancer: Another molecular Jekyll and Hyde?
    • Ehata S, Yokoyama Y, Takahashi K, Miyazono K. 2013. Bidirectional roles of bone morphogenetic proteins in cancer: Another molecular Jekyll and Hyde? Pathol Int 63: 287-296.
    • (2013) Pathol Int , vol.63 , pp. 287-296
    • Ehata, S.1    Yokoyama, Y.2    Takahashi, K.3    Miyazono, K.4
  • 40
    • 17644443919 scopus 로고    scopus 로고
    • Induction of the Sryrelated factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of C3H10T1/2 cells
    • Fernandez-Lloris R, Vinals F, Lopez-Rovira T, Harley V, Bartrons R, Rosa JL, Ventura F. 2003. Induction of the Sryrelated factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of C3H10T1/2 cells. Mol Endocrinol 17: 1332-1343.
    • (2003) Mol Endocrinol , vol.17 , pp. 1332-1343
    • Fernandez-Lloris, R.1    Vinals, F.2    Lopez-Rovira, T.3    Harley, V.4    Bartrons, R.5    Rosa, J.L.6    Ventura, F.7
  • 49
    • 0033625416 scopus 로고    scopus 로고
    • Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice
    • Goumans MJ, Mummery C. 2000. Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice. Int J Dev Biol 44: 253-265.
    • (2000) Int J Dev Biol , vol.44 , pp. 253-265
    • Goumans, M.J.1    Mummery, C.2
  • 51
    • 0037351880 scopus 로고    scopus 로고
    • The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
    • Greenwald J, Groppe J, Gray P, Wiater E, Kwiatkowski W, Vale W, Choe S. 2003. The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Mol Cell 11: 605-617.
    • (2003) Mol Cell , vol.11 , pp. 605-617
    • Greenwald, J.1    Groppe, J.2    Gray, P.3    Wiater, E.4    Kwiatkowski, W.5    Vale, W.6    Choe, S.7
  • 52
    • 0030042590 scopus 로고    scopus 로고
    • Three-dimensional structure of recombinant human osteogenic protein 1: Structural paradigm for the transforming growth factor b superfamily
    • Griffith DL, Keck PC, Sampath TK, Rueger DC, Carlson WD. 1996. Three-dimensional structure of recombinant human osteogenic protein 1: Structural paradigm for the transforming growth factor b superfamily. ProcNatl Acad Sci 93: 878-883.
    • (1996) Procnatl Acad Sci , vol.93 , pp. 878-883
    • Griffith, D.L.1    Keck, P.C.2    Sampath, T.K.3    Rueger, D.C.4    Carlson, W.D.5
  • 53
    • 34250663063 scopus 로고    scopus 로고
    • Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/ Rac/JNK-dependent signaling pathways in colon cancer cells
    • Grijelmo C, Rodrigue C, Svrcek M, Bruyneel E, Hendrix A, de Wever O, Gespach C. 2007. Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/ Rac/JNK-dependent signaling pathways in colon cancer cells. Cell Signal 19: 1722-1732.
    • (2007) Cell Signal , vol.19 , pp. 1722-1732
    • Grijelmo, C.1    Rodrigue, C.2    Svrcek, M.3    Bruyneel, E.4    Hendrix, A.5    De Wever, O.6    Gespach, C.7
  • 55
    • 84858332746 scopus 로고    scopus 로고
    • The signaling and functions of heterodimeric bone morphogenetic proteins
    • Guo J, Wu G. 2012. The signaling and functions of heterodimeric bone morphogenetic proteins. Cytokine Growth Factor Rev 23: 61-67.
    • (2012) Cytokine Growth Factor Rev , vol.23 , pp. 61-67
    • Guo, J.1    Wu, G.2
  • 57
    • 84918528600 scopus 로고    scopus 로고
    • Regulatory principles of pluripotency: From the ground state up
    • Hackett JA, Surani MA. 2014. Regulatory principles of pluripotency: From the ground state up. Cell Stem Cell 15: 416-430.
    • (2014) Cell Stem Cell , vol.15 , pp. 416-430
    • Hackett, J.A.1    Surani, M.A.2
  • 58
    • 84867903696 scopus 로고    scopus 로고
    • Pathogenic mutation of ALK2 inhibits induced pluripotent stem cell reprogramming and maintenance: Mechanisms of reprogramming and strategy for drug identification
    • Hamasaki M, Hashizume Y, Yamada Y, Katayama T, Hohjoh H, Fusaki N, Nakashima Y, Furuya H, Haga N, Takami Y. 2012. Pathogenic mutation of ALK2 inhibits induced pluripotent stem cell reprogramming and maintenance: Mechanisms of reprogramming and strategy for drug identification. Stem Cells 30: 2437-2449.
    • (2012) Stem Cells , vol.30 , pp. 2437-2449
    • Hamasaki, M.1    Hashizume, Y.2    Yamada, Y.3    Katayama, T.4    Hohjoh, H.5    Fusaki, N.6    Nakashima, Y.7    Furuya, H.8    Haga, N.9    Takami, Y.10
  • 62
    • 21344473027 scopus 로고    scopus 로고
    • First evidence supporting a potential role for the BMP/SMAD pathway in the pro-gression of oestrogen receptor-positive breast cancer
    • Helms MW, Packeisen J, August C, Schittek B, Boecker W, Brandt BH, Buerger H. 2005. First evidence supporting a potential role for the BMP/SMAD pathway in the pro-gression of oestrogen receptor-positive breast cancer. J Pathol 206: 366-376.
    • (2005) J Pathol , vol.206 , pp. 366-376
    • Helms, M.W.1    Packeisen, J.2    August, C.3    Schittek, B.4    Boecker, W.5    Brandt, B.H.6    Buerger, H.7
  • 63
    • 0033538447 scopus 로고    scopus 로고
    • Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells
    • Hollnagel A, Oehlmann V, Heymer J, Rüther U, Nordheim A. 1999. Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells. J Biol Chem 278: 19838-19845.
    • (1999) J Biol Chem , vol.278 , pp. 19838-19845
    • Hollnagel, A.1    Oehlmann, V.2    Heymer, J.3    Rüther, U.4    Nordheim, A.5
  • 64
    • 70849128432 scopus 로고    scopus 로고
    • Applications of small moleculeBMP inhibitors in physiology and disease
    • Hong CC, Yu PB. 2009. Applications of small moleculeBMP inhibitors in physiology and disease. Cytokine Growth Factor Rev 20: 409-418.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 409-418
    • Hong, C.C.1    Yu, P.B.2
  • 67
    • 84859074674 scopus 로고    scopus 로고
    • Noggin is required for early development of murine upper incisors
    • Hu X, Wang Y, He F, Li L, Zheng Y, Zhang Y, Chen YP. 2012. Noggin is required for early development of murine upper incisors. J Dent Res 91: 394-400.
    • (2012) J Dent Res , vol.91 , pp. 394-400
    • Hu, X.1    Wang, Y.2    He, F.3    Li, L.4    Zheng, Y.5    Zhang, Y.6    Chen, Y.P.7
  • 68
    • 0029933076 scopus 로고    scopus 로고
    • Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands
    • Ikeda T, Takahashi H, Suzuki A, Ueno N, Yokose S, Yamaguchi A, Yoshiki S. 1996. Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands. Dev Dyn 206: 318-329.
    • (1996) Dev Dyn , vol.206 , pp. 318-329
    • Ikeda, T.1    Takahashi, H.2    Suzuki, A.3    Ueno, N.4    Yokose, S.5    Yamaguchi, A.6    Yoshiki, S.7
  • 69
    • 72649101813 scopus 로고    scopus 로고
    • Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors
    • Ikeya M, Fukushima K, Kawada M, Onishi S, Furuta Y, Yonemura S, Kitamura T, Nosaka T, Sasai Y. 2010. Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors. Dev Biol 337: 405-414.
    • (2010) Dev Biol , vol.337 , pp. 405-414
    • Ikeya, M.1    Fukushima, K.2    Kawada, M.3    Onishi, S.4    Furuta, Y.5    Yonemura, S.6    Kitamura, T.7    Nosaka, T.8    Sasai, Y.9
  • 70
    • 0042661060 scopus 로고    scopus 로고
    • Heparan sulfate is required for bone morphogenetic protein-7 signaling
    • Irie A, Habuchi H, Kimata K, Sanai Y. 2003. Heparan sulfate is required for bone morphogenetic protein-7 signaling. Biochem Biophys Res Commun 308: 858-865.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 858-865
    • Irie, A.1    Habuchi, H.2    Kimata, K.3    Sanai, Y.4
  • 71
    • 0034093738 scopus 로고    scopus 로고
    • Smad6 is a Smad1/5-induced smad inhibitor. Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter
    • Ishida W, Hamamoto T, Kusanagi K, Yagi K, Kawabata M, Takehara K, Sampath TK, Kato M, Miyazono K. 2000. Smad6 is a Smad1/5-induced smad inhibitor. Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter. J Biol Chem 275: 6075-6079.
    • (2000) J Biol Chem , vol.275 , pp. 6075-6079
    • Ishida, W.1    Hamamoto, T.2    Kusanagi, K.3    Yagi, K.4    Kawabata, M.5    Takehara, K.6    Sampath, T.K.7    Kato, M.8    Miyazono, K.9
  • 73
    • 84904460051 scopus 로고    scopus 로고
    • Roles of TGF-β family signals in the fate determination of pluripotent stem cells
    • Itoh F, Watabe T, Miyazono K. 2014. Roles of TGF-β family signals in the fate determination of pluripotent stem cells. Semin Cell Dev Biol 32: 98-106.
    • (2014) Semin Cell Dev Biol , vol.32 , pp. 98-106
    • Itoh, F.1    Watabe, T.2    Miyazono, K.3
  • 74
    • 0037456847 scopus 로고    scopus 로고
    • Links between signal transduction, transcription and adhesion in epithelial bud development
    • Jamora C, DasGupta R, Kocieniewski P, Fuchs E. 2003. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422: 317-322.
    • (2003) Nature , vol.422 , pp. 317-322
    • Jamora, C.1    Dasgupta, R.2    Kocieniewski, P.3    Fuchs, E.4
  • 75
    • 0032980226 scopus 로고    scopus 로고
    • Developmental patterning in chondrocytic cultures by morphogenic gradients: BMP induces expression of Indian hedgehog and Noggin
    • Kameda T, Koike C, Saitoh K, Kuroiwa A, Iba H. 1999. Developmental patterning in chondrocytic cultures by morphogenic gradients: BMP induces expression of Indian hedgehog and Noggin. Genes Cells 4: 175-184.
    • (1999) Genes Cells , vol.4 , pp. 175-184
    • Kameda, T.1    Koike, C.2    Saitoh, K.3    Kuroiwa, A.4    Iba, H.5
  • 76
    • 84882579079 scopus 로고    scopus 로고
    • The skeleton in the closet
    • Kaplan FS. 2013. The skeleton in the closet. Gene 528: 7-11.
    • (2013) Gene , vol.528 , pp. 7-11
    • Kaplan, F.S.1
  • 77
    • 41749093830 scopus 로고    scopus 로고
    • Molecular biology and pathology of lymphangiogenesis
    • Karpanen T, Alitalo K. 2008.Molecular biology and pathology of lymphangiogenesis. Annu Rev Pathol 3: 367-397.
    • (2008) Annu Rev Pathol , vol.3 , pp. 367-397
    • Karpanen, T.1    Alitalo, K.2
  • 79
    • 77954143494 scopus 로고    scopus 로고
    • Heterotopic bone formation induced by bone morphogenetic protein signaling: Fibrodysplasia ossificans progressiva
    • Katagiri T. 2010. Heterotopic bone formation induced by bone morphogenetic protein signaling: Fibrodysplasia ossificans progressiva. J Oral Biosci 52: 33-41.
    • (2010) J Oral Biosci , vol.52 , pp. 33-41
    • Katagiri, T.1
  • 80
    • 84867572714 scopus 로고    scopus 로고
    • Recent topics in fibrodysplasia ossificans progressiva
    • Katagiri T. 2012. Recent topics in fibrodysplasia ossificans progressiva. J Oral Biosci 54: 119-123.
    • (2012) J Oral Biosci , vol.54 , pp. 119-123
    • Katagiri, T.1
  • 83
    • 0036732838 scopus 로고    scopus 로고
    • Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis
    • Katagiri T, Imada M, Yanai T, Suda T, Takahashi N, Kamijo R. 2002. Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis. Genes Cells 7: 949-960.
    • (2002) Genes Cells , vol.7 , pp. 949-960
    • Katagiri, T.1    Imada, M.2    Yanai, T.3    Suda, T.4    Takahashi, N.5    Kamijo, R.6
  • 85
    • 0034685657 scopus 로고    scopus 로고
    • Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity
    • Kawai S, Faucheu C, Gallea S, Spinella-Jaegle S, Atfi A, Baron R, Roman SR. 2000. Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity. Biochem Biophys Res Commun. 271: 682-687.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 682-687
    • Kawai, S.1    Faucheu, C.2    Gallea, S.3    Spinella-Jaegle, S.4    Atfi, A.5    Baron, R.6    Roman, S.R.7
  • 87
    • 0026440993 scopus 로고
    • The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF-β superfamily
    • Kingsley DM, Bland AE, Grubber JM, Marker PC, Russell LB, Copeland NG, Jenkins NA. 1992. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF-β superfamily. Cell 71: 399-410.
    • (1992) Cell , vol.71 , pp. 399-410
    • Kingsley, D.M.1    Bland, A.E.2    Grubber, J.M.3    Marker, P.C.4    Russell, L.B.5    Copeland, N.G.6    Jenkins, N.A.7
  • 88
    • 0034043106 scopus 로고    scopus 로고
    • Crystal structure of the BMP-2-BRIA ectodomain complex
    • Kirsch T, Sebald W, Dreyer MK. 2000. Crystal structure of the BMP-2-BRIA ectodomain complex. Nat Struct Biol 7: 492-496.
    • (2000) Nat Struct Biol , vol.7 , pp. 492-496
    • Kirsch, T.1    Sebald, W.2    Dreyer, M.K.3
  • 89
    • 0038044657 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 mediates apoptosis of capillary endothelial cells during rat pupillary membrane regression
    • Kiyono M, Shibuya M. 2003. Bone morphogenetic protein 4 mediates apoptosis of capillary endothelial cells during rat pupillary membrane regression. Mol Cell Biol 23: 4627-4636.
    • (2003) Mol Cell Biol , vol.23 , pp. 4627-4636
    • Kiyono, M.1    Shibuya, M.2
  • 92
    • 0029980449 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 does not alter the differentiation pathway of committed progenitors of osteoblasts and chondroblasts
    • Komaki M, Katagiri T, Suda T. 1996. Bone morphogenetic protein-2 does not alter the differentiation pathway of committed progenitors of osteoblasts and chondroblasts. Cell Tissue Res 284: 9-17.
    • (1996) Cell Tissue Res , vol.284 , pp. 9-17
    • Komaki, M.1    Katagiri, T.2    Suda, T.3
  • 93
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • Korchynskyi O, ten Dijke P. 2002. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem 277: 4883-4891.
    • (2002) J Biol Chem , vol.277 , pp. 4883-4891
    • Korchynskyi, O.1    Ten Dijke, P.2
  • 94
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor b and bone morphogenetic protein
    • Kowanetz M, Valcourt U, Bergström R, Heldin CH, Moustakas A. 2004. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor b and bone morphogenetic protein. Mol Cell Biol 24: 4241-4254.
    • (2004) Mol Cell Biol , vol.24 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergström, R.3    Heldin, C.H.4    Moustakas, A.5
  • 95
    • 0034671830 scopus 로고    scopus 로고
    • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle
    • Kulessa H, Turk G, Hogan BL. 2000. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. EMBO J 19: 6664-6674.
    • (2000) EMBO J , vol.19 , pp. 6664-6674
    • Kulessa, H.1    Turk, G.2    Hogan, B.L.3
  • 96
    • 0242521297 scopus 로고    scopus 로고
    • Identification of a secreted BMP antagonist, ectodin, integrated BMP, FGF, and SHH signals from the tooth enamel knot
    • Laurikkala J, Kasai Y, Pakkasjarvi L, Thesleff I, Itoh N. 2003. Identification of a secreted BMP antagonist, ectodin, integrated BMP, FGF, and SHH signals from the tooth enamel knot. Dev Biol 264: 91-105.
    • (2003) Dev Biol , vol.264 , pp. 91-105
    • Laurikkala, J.1    Kasai, Y.2    Pakkasjarvi, L.3    Thesleff, I.4    Itoh, N.5
  • 97
    • 84868455051 scopus 로고    scopus 로고
    • Hairy tale of signaling in hair follicle development and cycling
    • Lee J, Tumbar T. 2012. Hairy tale of signaling in hair follicle development and cycling. Semin Cell Dev Biol 23: 906-916.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 906-916
    • Lee, J.1    Tumbar, T.2
  • 98
    • 37349067098 scopus 로고    scopus 로고
    • Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
    • Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, et al. 2008. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 13: 69-80.
    • (2008) Cancer Cell , vol.13 , pp. 69-80
    • Lee, J.1    Son, M.J.2    Woolard, K.3    Donin, N.M.4    Li, A.5    Cheng, C.H.6    Kotliarova, S.7    Kotliarov, Y.8    Walling, J.9    Ahn, S.10
  • 99
    • 33751317476 scopus 로고    scopus 로고
    • A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2
    • Lehmann K, Seemann P, Boergermann J, Morin G, Reif S, Knaus P, Mundlos S. 2006. A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2. Eur J Hum Genet 14: 1248-1254.
    • (2006) Eur J Hum Genet , vol.14 , pp. 1248-1254
    • Lehmann, K.1    Seemann, P.2    Boergermann, J.3    Morin, G.4    Reif, S.5    Knaus, P.6    Mundlos, S.7
  • 104
    • 0036479133 scopus 로고    scopus 로고
    • Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene
    • Lopez-Rovira T, Chalaux E, Massagué J, Rosa JL, Ventura F. 2002. Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene. J Biol Chem 277: 3176-3185.
    • (2002) J Biol Chem , vol.277 , pp. 3176-3185
    • Lopez-Rovira, T.1    Chalaux, E.2    Massagué, J.3    Rosa, J.L.4    Ventura, F.5
  • 106
    • 0028882261 scopus 로고
    • BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
    • Luo G, Hofmann C, Bronckers AL, Sohocki M, Bradley A, Karsenty G. 1995. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev 9: 2808-2820.
    • (1995) Genes Dev , vol.9 , pp. 2808-2820
    • Luo, G.1    Hofmann, C.2    Bronckers, A.L.3    Sohocki, M.4    Bradley, A.5    Karsenty, G.6
  • 107
    • 0024761677 scopus 로고
    • Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-b-like genes coordinately regulate aspects of embryonic development
    • Lyons KM, Pelton RW, Hogan BL. 1989. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-b-like genes coordinately regulate aspects of embryonic development. Genes Dev 3: 1657-1668.
    • (1989) Genes Dev , vol.3 , pp. 1657-1668
    • Lyons, K.M.1    Pelton, R.W.2    Hogan, B.L.3
  • 109
    • 1442313955 scopus 로고    scopus 로고
    • Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells
    • Maeda S, Hayashi M, Komiya S, Imamura T, Miyazono K. 2004. Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells. EMBO J 23: 552-563.
    • (2004) EMBO J , vol.23 , pp. 552-563
    • Maeda, S.1    Hayashi, M.2    Komiya, S.3    Imamura, T.4    Miyazono, K.5
  • 113
    • 0033052036 scopus 로고    scopus 로고
    • Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11
    • McPherron AC, Lawler AM, Lee SJ. 1999. Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.Nat Genet 22: 260-264.
    • (1999) Nat Genet , vol.22 , pp. 260-264
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 114
  • 116
    • 11244256523 scopus 로고    scopus 로고
    • BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells
    • Miyazaki H, Watabe T, Kitamura T, Miyazono K. 2004. BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells. Oncogene 23: 9326-9335.
    • (2004) Oncogene , vol.23 , pp. 9326-9335
    • Miyazaki, H.1    Watabe, T.2    Kitamura, T.3    Miyazono, K.4
  • 117
    • 75649127963 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptors and signal transduction
    • Miyazono K, Kamiya Y, Morikawa M. 2010. Bone morphogenetic protein receptors and signal transduction. J Biochem 147: 35-51.
    • (2010) J Biochem , vol.147 , pp. 35-51
    • Miyazono, K.1    Kamiya, Y.2    Morikawa, M.3
  • 120
    • 0043133835 scopus 로고    scopus 로고
    • BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation
    • Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, Bautch VL, Conlon FL, Patterson C. 2003. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol 23: 5664-5579.
    • (2003) Mol Cell Biol , vol.23 , pp. 5664-5679
    • Moser, M.1    Binder, O.2    Wu, Y.3    Aitsebaomo, J.4    Ren, R.5    Bode, C.6    Bautch, V.L.7    Conlon, F.L.8    Patterson, C.9
  • 123
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108: 17-29.
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    De Crombrugghe, B.7
  • 124
    • 0038445467 scopus 로고    scopus 로고
    • Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cells
    • Nakayama N, Duryea D, Manoukian R, Chow G, Han CY. 2003. Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cells. J Cell Sci 116: 2015-2028.
    • (2003) J Cell Sci , vol.116 , pp. 2015-2028
    • Nakayama, N.1    Duryea, D.2    Manoukian, R.3    Chow, G.4    Han, C.Y.5
  • 125
    • 84929486079 scopus 로고    scopus 로고
    • The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathways
    • Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. 2015. The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathways. J Cell Sci 128: 1835-1847.
    • (2015) J Cell Sci , vol.128 , pp. 1835-1847
    • Nam, D.1    Guo, B.2    Chatterjee, S.3    Chen, M.H.4    Nelson, D.5    Yechoor, V.K.6    Ma, K.7
  • 126
    • 70350446976 scopus 로고    scopus 로고
    • Site-specific cleavage of BMP4 by furin, PC6, and PC7
    • Nelsen SM, Christian JL. 2009. Site-specific cleavage of BMP4 by furin, PC6, and PC7. J Biol Chem 284: 27157-27166.
    • (2009) J Biol Chem , vol.284 , pp. 27157-27166
    • Nelsen, S.M.1    Christian, J.L.2
  • 127
    • 77949898210 scopus 로고    scopus 로고
    • ALK1 signaling regulates early postnatal lymphatic vessel development
    • Niessen K, Zhang G, Ridgway JB, Chen H, Yan M. 2010. ALK1 signaling regulates early postnatal lymphatic vessel development. Blood 115: 1654-1661.
    • (2010) Blood , vol.115 , pp. 1654-1661
    • Niessen, K.1    Zhang, G.2    Ridgway, J.B.3    Chen, H.4    Yan, M.5
  • 128
    • 77955298048 scopus 로고    scopus 로고
    • Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2-and BMP6-mediated signaling and gene expression
    • Nili M, Shinde U, Rotwein P. 2010. Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2-and BMP6-mediated signaling and gene expression. J Biol Chem 285: 24783-24792.
    • (2010) J Biol Chem , vol.285 , pp. 24783-24792
    • Nili, M.1    Shinde, U.2    Rotwein, P.3
  • 129
    • 84862012341 scopus 로고    scopus 로고
    • Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals
    • Nishimori H, Ehata S, Suzuki HI, Katsuno Y, Miyazono K. 2012. Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals. J Biol Chem 287: 20037-20046.
    • (2012) J Biol Chem , vol.287 , pp. 20037-20046
    • Nishimori, H.1    Ehata, S.2    Suzuki, H.I.3    Katsuno, Y.4    Miyazono, K.5
  • 130
    • 84896716245 scopus 로고    scopus 로고
    • BMP signaling and its modifiers in kidney development
    • Nishinakamura R, Sakaguchi M. 2014. BMP signaling and its modifiers in kidney development. Pediatr Nephrol 29: 681-686.
    • (2014) Pediatr Nephrol , vol.29 , pp. 681-686
    • Nishinakamura, R.1    Sakaguchi, M.2
  • 136
    • 84957431988 scopus 로고    scopus 로고
    • Common mutations in ALK2/ ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders
    • Pacifici M, Shore EM. 2016. Common mutations in ALK2/ ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders. Cytokine Growth Factor Rev 27: 93-104.
    • (2016) Cytokine Growth Factor Rev , vol.27 , pp. 93-104
    • Pacifici, M.1    Shore, E.M.2
  • 137
    • 0027403003 scopus 로고
    • Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo
    • Padgett RW, Wozney JM, Gelbart WM. 1993. Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo. Proc Natl Acad Sci 90: 2905-2909.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 2905-2909
    • Padgett, R.W.1    Wozney, J.M.2    Gelbart, W.M.3
  • 139
    • 78149240961 scopus 로고    scopus 로고
    • Somatic frameshift mutations of bone morphogenic protein receptor 2 gene in gastric and colorectal cancers with microsatellite instability
    • Park SW, Hur SY, Yoo NJ, Lee SH. 2010. Somatic frameshift mutations of bone morphogenic protein receptor 2 gene in gastric and colorectal cancers with microsatellite instability. APMIS 118: 824-829.
    • (2010) APMIS , vol.118 , pp. 824-829
    • Park, S.W.1    Hur, S.Y.2    Yoo, N.J.3    Lee, S.H.4
  • 140
    • 0034520158 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblasts
    • Pereira RC, Economides AN, Canalis E. 2000. Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblasts. Endocrinology 141: 4558-4563.
    • (2000) Endocrinology , vol.141 , pp. 4558-4563
    • Pereira, R.C.1    Economides, A.N.2    Canalis, E.3
  • 142
    • 0030665807 scopus 로고    scopus 로고
    • Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity
    • Piccolo S, Agius E, Lu B, Goodman S, Dale L, De Robertis EM. 1997. Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity. Cell 91: 407-416.
    • (1997) Cell , vol.91 , pp. 407-416
    • Piccolo, S.1    Agius, E.2    Lu, B.3    Goodman, S.4    Dale, L.5    De Robertis, E.M.6
  • 147
    • 12544259720 scopus 로고    scopus 로고
    • Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration
    • Rothhammer T, Poser I, Soncin F, Bataille F, Moser M, Bosserhoff AK. 2005. Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration. Cancer Res 65: 448-456.
    • (2005) Cancer Res , vol.65 , pp. 448-456
    • Rothhammer, T.1    Poser, I.2    Soncin, F.3    Bataille, F.4    Moser, M.5    Bosserhoff, A.K.6
  • 148
    • 0029985256 scopus 로고    scopus 로고
    • Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity
    • Ruppert R, Hoffmann E, Sebald W. 1996. Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity. Eur J Biochem 237: 295-302.
    • (1996) Eur J Biochem , vol.237 , pp. 295-302
    • Ruppert, R.1    Hoffmann, E.2    Sebald, W.3
  • 151
    • 0040991685 scopus 로고
    • Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix
    • Sampath TK, Reddi AH. 1983. Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix. Proc Natl Acad Sci 80: 6591-6595.
    • (1983) Proc Natl Acad Sci , vol.80 , pp. 6591-6595
    • Sampath, T.K.1    Reddi, A.H.2
  • 153
    • 0026739256 scopus 로고
    • Recombinant human osteogenic protein-1 (HOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro
    • Sampath TK, Maliakal JC, Hauschka PV, Jones WK, Sasak H, Tucker RF, White KH, Coughlin JE, Tucker MM, Pang RHL, et al. 1992. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J Biol Chem 267: 20352-20362.
    • (1992) J Biol Chem , vol.267 , pp. 20352-20362
    • Sampath, T.K.1    Maliakal, J.C.2    Hauschka, P.V.3    Jones, W.K.4    Sasak, H.5    Tucker, R.F.6    White, K.H.7    Coughlin, J.E.8    Tucker, M.M.9    Pang, R.10
  • 154
    • 0027161383 scopus 로고
    • Drosophila transforming growth factor b superfamily proteins induce endochondral bone formation in mammals
    • Sampath TK, Rashka KE, Doctor JS, Tucker RF, Hoffmann FM. 1993. Drosophila transforming growth factor b superfamily proteins induce endochondral bone formation in mammals. Proc Natl Acad Sci 90: 6004-6008.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 6004-6008
    • Sampath, T.K.1    Rashka, K.E.2    Doctor, J.S.3    Tucker, R.F.4    Hoffmann, F.M.5
  • 158
    • 14844292085 scopus 로고    scopus 로고
    • Crystal structure of recombinant human growth and differentiation factor 5: Evidence for interaction of the type I and type II receptor-binding sites
    • Schreuder H, Liesum A, Pohl J, Kruse M, Koyama M. 2005. Crystal structure of recombinant human growth and differentiation factor 5: Evidence for interaction of the type I and type II receptor-binding sites. Biochem Biophys Res Commun 329: 1076-1086.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 1076-1086
    • Schreuder, H.1    Liesum, A.2    Pohl, J.3    Kruse, M.4    Koyama, M.5
  • 160
    • 84865690922 scopus 로고
    • Senn on the healing of aseptic bone cavities by implantation of antiseptic decalcified bone
    • Senn N. 1889. Senn on the healing of aseptic bone cavities by implantation of antiseptic decalcified bone. Ann Surg 10: 352-368.
    • (1889) Ann Surg , vol.10 , pp. 352-368
    • Senn, N.1
  • 161
    • 0037330644 scopus 로고    scopus 로고
    • Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes
    • Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM. 2003.Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol 254: 116-130.
    • (2003) Dev Biol , vol.254 , pp. 116-130
    • Settle, S.H.1    Rountree, R.B.2    Sinha, A.3    Thacker, A.4    Higgins, K.5    Kingsley, D.M.6
  • 163
    • 70449366408 scopus 로고    scopus 로고
    • The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
    • Shen Q, Little SC, Xu M, Haupt J, Ast C, Katagiri T, Mundlos S, Seemann P, Kaplan FS, Mullins MC, et al. 2009. The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J Clin Invest 119: 3462-3472.
    • (2009) J Clin Invest , vol.119 , pp. 3462-3472
    • Shen, Q.1    Little, S.C.2    Xu, M.3    Haupt, J.4    Ast, C.5    Katagiri, T.6    Mundlos, S.7    Seemann, P.8    Kaplan, F.S.9    Mullins, M.C.10
  • 164
    • 84876296343 scopus 로고    scopus 로고
    • Identification of a novel bone morphogenetic protein (BMP)-inducible transcript, BMP-inducible transcript-1, by utilizing the conserved BMP-responsive elements in the Id genes
    • Shin M, Ohte S, Fukuda T, Sasanuma H, Yoneyama K, Kokabu S, Miyamoto A, Tsukamoto S, Hohjoh H, Jimi E, et al. 2013. Identification of a novel bone morphogenetic protein (BMP)-inducible transcript, BMP-inducible transcript-1, by utilizing the conserved BMP-responsive elements in the Id genes. J Bone Miner Metab 31: 34-43.
    • (2013) J Bone Miner Metab , vol.31 , pp. 34-43
    • Shin, M.1    Ohte, S.2    Fukuda, T.3    Sasanuma, H.4    Yoneyama, K.5    Kokabu, S.6    Miyamoto, A.7    Tsukamoto, S.8    Hohjoh, H.9    Jimi, E.10
  • 165
    • 81255124262 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 and-4 play tumor suppressive roles in human diffuse-type gastric carcinoma
    • Shirai YT, Ehata S, Yashiro M, Yanagihara K, Hirakawa K, Miyazono K. 2011. Bone morphogenetic protein-2 and-4 play tumor suppressive roles in human diffuse-type gastric carcinoma. Am J Pathol 179: 2920-2930.
    • (2011) Am J Pathol , vol.179 , pp. 2920-2930
    • Shirai, Y.T.1    Ehata, S.2    Yashiro, M.3    Yanagihara, K.4    Hirakawa, K.5    Miyazono, K.6
  • 168
    • 0028232724 scopus 로고
    • Limb alterations in brachypodism mice due to mutations in a new member of the TGFb-superfamily
    • Storm EE, Huynh TV, Copeland NG, Jenkins NA, Kingsley DM, Lee SJ. 1994. Limb alterations in brachypodism mice due to mutations in a new member of the TGFb-superfamily. Nature 368: 639-643.
    • (1994) Nature , vol.368 , pp. 639-643
    • Storm, E.E.1    Huynh, T.V.2    Copeland, N.G.3    Jenkins, N.A.4    Kingsley, D.M.5    Lee, S.J.6
  • 171
    • 39049131134 scopus 로고    scopus 로고
    • BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling
    • Suzuki Y, Montagne K, Nishihara A, Watabe T, Miyazono K. 2008. BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling. J Biochem 143: 199-206.
    • (2008) J Biochem , vol.143 , pp. 199-206
    • Suzuki, Y.1    Montagne, K.2    Nishihara, A.3    Watabe, T.4    Miyazono, K.5
  • 172
    • 77952343641 scopus 로고    scopus 로고
    • BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo
    • Suzuki Y, Ohga N, Morishita Y, Hida K, Miyazono K, Watabe T. 2010. BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo. J Cell Sci 123: 1684-1692.
    • (2010) J Cell Sci , vol.123 , pp. 1684-1692
    • Suzuki, Y.1    Ohga, N.2    Morishita, Y.3    Hida, K.4    Miyazono, K.5    Watabe, T.6
  • 174
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 175
  • 179
    • 33745898241 scopus 로고    scopus 로고
    • Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6
    • Truksa J, Peng H, Lee P, Beutler E. 2006. Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6. Proc Natl Acad Sci 103: 10289-10293.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 10289-10293
    • Truksa, J.1    Peng, H.2    Lee, P.3    Beutler, E.4
  • 184
    • 7344251776 scopus 로고    scopus 로고
    • Interactions between Bmp-4 and Msx-1 act to restrict gene expression to odontogenic mesenchyme
    • Tucker AS, Al Khamis A, Sharpe PT. 1998a. Interactions between Bmp-4 and Msx-1 act to restrict gene expression to odontogenic mesenchyme. Dev Dyn 212: 533-539.
    • (1998) Dev Dyn , vol.212 , pp. 533-539
    • Tucker, A.S.1    Al Khamis, A.2    Sharpe, P.T.3
  • 185
    • 0032491409 scopus 로고    scopus 로고
    • Transformation of tooth type induced by inhibition of BMP signaling
    • Tucker AS, Matthews KL, Sharpe PT. 1998b. Transformation of tooth type induced by inhibition of BMP signaling. Science 282: 1136-1138.
    • (1998) Science , vol.282 , pp. 1136-1138
    • Tucker, A.S.1    Matthews, K.L.2    Sharpe, P.T.3
  • 187
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • Urist MR. 1965. Bone: Formation by autoinduction. Science 150: 893-899.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 188
    • 0015155737 scopus 로고
    • Bone morphogenetic protein
    • Urist MR, Strates BS. 1971. Bone morphogenetic protein. J Dent Res 50: 1392-1406.
    • (1971) J Dent Res , vol.50 , pp. 1392-1406
    • Urist, M.R.1    Strates, B.S.2
  • 189
    • 0027363024 scopus 로고
    • Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development
    • Vainio S, Karavanova I, Jowett A, Thesleff I. 1993. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75: 45-58.
    • (1993) Cell , vol.75 , pp. 45-58
    • Vainio, S.1    Karavanova, I.2    Jowett, A.3    Thesleff, I.4
  • 190
    • 0037159280 scopus 로고    scopus 로고
    • Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells
    • Valdimarsdottir G, Goumans MJ, Rosendahl A, Brugman M, Itoh S, Lebrin F, Sideras P, ten Dijke P. 2002. Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells. Circulation 106: 2263-2270.
    • (2002) Circulation , vol.106 , pp. 2263-2270
    • Valdimarsdottir, G.1    Goumans, M.J.2    Rosendahl, A.3    Brugman, M.4    Itoh, S.5    Lebrin, F.6    Sideras, P.7    Ten Dijke, P.8
  • 193
    • 0032128140 scopus 로고    scopus 로고
    • Osteogenic protein-1 (Bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat
    • Vukicevic S, Basic V, Rogic D, Basic N, Shih MS, Shepard A, JinD, Dattatreymamurty B, JonesW, Dorai H, et al. 1998. Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat. J Clin Invest 102: 202-214.
    • (1998) J Clin Invest , vol.102 , pp. 202-214
    • Vukicevic, S.1    Basic, V.2    Rogic, D.3    Basic, N.4    Shih, M.S.5    Shepard, A.6
  • 196
    • 0027185702 scopus 로고
    • Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 cells and 3T3 cells
    • Wang EA, Israel DI, Kelly S, Luxenberg DP. 1993. Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 cells and 3T3 cells. Growth Factors 9: 57-71.
    • (1993) Growth Factors , vol.9 , pp. 57-71
    • Wang, E.A.1    Israel, D.I.2    Kelly, S.3    Luxenberg, D.P.4
  • 197
    • 7744246082 scopus 로고    scopus 로고
    • Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation
    • Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I. 2004. Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell 7: 719-730.
    • (2004) Dev Cell , vol.7 , pp. 719-730
    • Wang, X.P.1    Suomalainen, M.2    Jorgez, C.J.3    Matzuk, M.M.4    Werner, S.5    Thesleff, I.6
  • 199
    • 84864130274 scopus 로고    scopus 로고
    • BMPactivity is required for tooth development from the lamina to bud stage
    • Wang Y, Li L, Zheng Y, Yuan G, Yang G, He F, Chen Y. 2012. BMPactivity is required for tooth development from the lamina to bud stage. J Dent Res 91: 690-695.
    • (2012) J Dent Res , vol.91 , pp. 690-695
    • Wang, Y.1    Li, L.2    Zheng, Y.3    Yuan, G.4    Yang, G.5    He, F.6    Chen, Y.7
  • 200
    • 84938917325 scopus 로고    scopus 로고
    • Activation of the BMP-BMPR pathway conferred resistance to EGFR-TKIs in lung squamous cell carcinoma patients with EGFR mutations
    • Wang Z, Shen Z, Li Z, Duan J, Fu S, Liu Z, Bai H, Zhang Z, Zhao J, Wang X, et al. 2015. Activation of the BMP-BMPR pathway conferred resistance to EGFR-TKIs in lung squamous cell carcinoma patients with EGFR mutations. Proc Natl Acad Sci 112: 9990-9995.
    • (2015) Proc Natl Acad Sci , vol.112 , pp. 9990-9995
    • Wang, Z.1    Shen, Z.2    Li, Z.3    Duan, J.4    Fu, S.5    Liu, Z.6    Bai, H.7    Zhang, Z.8    Zhao, J.9    Wang, X.10
  • 202
    • 82755192867 scopus 로고    scopus 로고
    • Bone morphogenetic protein functions as a context-dependent angiogenic cue in vertebrates
    • Wiley DM, Jin SW. 2011. Bone morphogenetic protein functions as a context-dependent angiogenic cue in vertebrates. Semin Cell Dev Biol 22: 1012-1018
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 1012-1018
    • Wiley, D.M.1    Jin, S.W.2
  • 205
    • 84859912590 scopus 로고    scopus 로고
    • Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification
    • Wosczyna MN, Biswas AA, Cogswell CA, Goldhamer DJ. 2012. Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification. J Bone Miner Res 27: 1004-1017.
    • (2012) J Bone Miner Res , vol.27 , pp. 1004-1017
    • Wosczyna, M.N.1    Biswas, A.A.2    Cogswell, C.A.3    Goldhamer, D.J.4
  • 208
    • 0034914422 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 (BMP-2) signaling to the Col2a1 gene in chondroblasts requires the homeobox gene Dlx-2
    • Xu SC, Harris MA, Rubenstein JL, Mundy GR, Harris SE. 2001. Bone morphogenetic protein-2 (BMP-2) signaling to the Col2a1 gene in chondroblasts requires the homeobox gene Dlx-2. DNA Cell Biol 20: 359-365.
    • (2001) DNA Cell Biol , vol.20 , pp. 359-365
    • Xu, S.C.1    Harris, M.A.2    Rubenstein, J.L.3    Mundy, G.R.4    Harris, S.E.5
  • 211
    • 21344467705 scopus 로고    scopus 로고
    • Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
    • Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P. 2005. Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res 65: 5769-5777.
    • (2005) Cancer Res , vol.65 , pp. 5769-5777
    • Yang, S.1    Zhong, C.2    Frenkel, B.3    Reddi, A.H.4    Roy-Burman, P.5
  • 212
    • 84891712260 scopus 로고    scopus 로고
    • Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a b-catenin-dependent manner
    • Yang Z, Hai B, Qin L, Ti X, Shangguan L, Zhao Y, Wiggins L, Liu Y, Feng JQ, Chang JY, et al. 2013. Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a b-catenin-dependent manner. Mol Cell Biol 33: 4732-4744.
    • (2013) Mol Cell Biol , vol.33 , pp. 4732-4744
    • Yang, Z.1    Hai, B.2    Qin, L.3    Ti, X.4    Shangguan, L.5    Zhao, Y.6    Wiggins, L.7    Liu, Y.8    Feng, J.Q.9    Chang, J.Y.10
  • 213
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying QL, Nichols J, Chambers I, Smith A. 2003. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115: 281-292.
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 216
    • 21644447416 scopus 로고    scopus 로고
    • BMP type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells
    • Yu PB, Beppu H, Kawai N, Li E, Bloch KD. 2005. BMP type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells. J Biol Chem 280: 24443-24450.
    • (2005) J Biol Chem , vol.280 , pp. 24443-24450
    • Yu, P.B.1    Beppu, H.2    Kawai, N.3    Li, E.4    Bloch, K.D.5
  • 219
    • 80053197517 scopus 로고    scopus 로고
    • Recombinant BMP 4/7 fusion protein induces differentiation of bone marrow stem cells
    • Yuan S, Pan Q, Liu W, Wu B, Han X, Bi Z. 2011. Recombinant BMP 4/7 fusion protein induces differentiation of bone marrow stem cells. J Cell Biochem 112: 3054-3060.
    • (2011) J Cell Biochem , vol.112 , pp. 3054-3060
    • Yuan, S.1    Pan, Q.2    Liu, W.3    Wu, B.4    Han, X.5    Bi, Z.6
  • 220
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Muller GA, Kalluri R. 2003. BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-967.
    • (2003) Nat Med , vol.9 , pp. 964-967
    • Zeisberg, M.1    Bottiglio, C.2    Kumar, N.3    Maeshima, Y.4    Strutz, F.5    Muller, G.A.6    Kalluri, R.7
  • 221
    • 0036714198 scopus 로고    scopus 로고
    • Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis
    • Zhang Z, Song Y, Zhao X, Zhang X, Fermin C, Chen Y. 2002. Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis. Development 129: 4135-4146.
    • (2002) Development , vol.129 , pp. 4135-4146
    • Zhang, Z.1    Song, Y.2    Zhao, X.3    Zhang, X.4    Fermin, C.5    Chen, Y.6
  • 222
    • 0042978771 scopus 로고    scopus 로고
    • ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development
    • Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O’Keefe RJ. 2003. ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. J Bone Miner Res 18: 1593-1604.
    • (2003) J Bone Miner Res , vol.18 , pp. 1593-1604
    • Zhang, D.1    Schwarz, E.M.2    Rosier, R.N.3    Zuscik, M.J.4    Puzas, J.E.5    O’Keefe, R.J.6
  • 223
    • 84865133667 scopus 로고    scopus 로고
    • BMP4 administration induces differentiation of CD133þ hepatic cancer stem cells, blocking their contributions to hepatocellular carcinoma
    • Zhang L, Sun H, Zhao F, Lu P, Ge C, Li H, Hou H, Yan M, Chen T, Jiang G, et al. 2012. BMP4 administration induces differentiation of CD133þ hepatic cancer stem cells, blocking their contributions to hepatocellular carcinoma. Cancer Res 72: 4276-4285.
    • (2012) Cancer Res , vol.72 , pp. 4276-4285
    • Zhang, L.1    Sun, H.2    Zhao, F.3    Lu, P.4    Ge, C.5    Li, H.6    Hou, H.7    Yan, M.8    Chen, T.9    Jiang, G.10


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