-
1
-
-
0030050973
-
Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2
-
Johnson DW, Berg JN, Baldwin MA, et al. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet. 1996;13:189-195.
-
(1996)
Nat Genet
, vol.13
, pp. 189-195
-
-
Johnson, D.W.1
Berg, J.N.2
Baldwin, M.A.3
-
4
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 2003;113:685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
5
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature. 2003;425:577-584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
6
-
-
0027525105
-
Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors
-
Attisano L, Carcamo J, Ventura F, Weis FM, Massague J, Wrana JL. Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors. Cell. 1993;75:671-680.
-
(1993)
Cell
, vol.75
, pp. 671-680
-
-
Attisano, L.1
Carcamo, J.2
Ventura, F.3
Weis, F.M.4
Massague, J.5
Wrana, J.L.6
-
7
-
-
0033524945
-
Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors
-
Chen YG, Massague J. Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors. J Biol Chem. 1999;274:3672-3677.
-
(1999)
J Biol Chem
, vol.274
, pp. 3672-3677
-
-
Chen, Y.G.1
Massague, J.2
-
8
-
-
0028295762
-
Characterization of type I receptors for transforming growth factor-beta and activin
-
ten Dijke P, Yamashita H, Ichijo H, et al. Characterization of type I receptors for transforming growth factor-beta and activin. Science. 1994;264:101-104.
-
(1994)
Science
, vol.264
, pp. 101-104
-
-
ten Dijke, P.1
Yamashita, H.2
Ichijo, H.3
-
9
-
-
0028359376
-
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin
-
Carcamo J, Weis FM, Ventura F, et al. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. Mol Cell Biol. 1994;14:3810-3821.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3810-3821
-
-
Carcamo, J.1
Weis, F.M.2
Ventura, F.3
-
10
-
-
0029872980
-
Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I receptors
-
De Winter JP, De Vries CJ, Van Achterberg TA, et al. Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I receptors. Exp Cell Res. 1996;224:323-334.
-
(1996)
Exp Cell Res
, vol.224
, pp. 323-334
-
-
De Winter, J.P.1
De Vries, C.J.2
Van Achterberg, T.A.3
-
11
-
-
12944273545
-
Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis
-
Oh SP, Seki T, Goss KA, et al. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A. 2000;97:2626-2631.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2626-2631
-
-
Oh, S.P.1
Seki, T.2
Goss, K.A.3
-
12
-
-
0034194584
-
Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2
-
Abdalla SA, Pece-Barbara N, Vera S, et al. Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2. Hum Mol Genet. 2000;9:1227-1237.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1227-1237
-
-
Abdalla, S.A.1
Pece-Barbara, N.2
Vera, S.3
-
13
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
-
Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J. 2002;21:1743-1753.
-
(2002)
EMBO J
, vol.21
, pp. 1743-1753
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
ten Dijke, P.6
-
14
-
-
0242330126
-
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
-
Goumans MJ, Valdimarsdottir G, Itoh S, et al. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol Cell. 2003;12:817-828.
-
(2003)
Mol Cell
, vol.12
, pp. 817-828
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
-
15
-
-
30944436695
-
Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development
-
Seki T, Hong KH, Oh SP. Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development. Lab Invest. 2006;86:116-129.
-
(2006)
Lab Invest
, vol.86
, pp. 116-129
-
-
Seki, T.1
Hong, K.H.2
Oh, S.P.3
-
16
-
-
0033537831
-
Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1
-
Lux A, Attisano L, Marchuk DA. Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1. J Biol Chem. 1999;274:9984-9992.
-
(1999)
J Biol Chem
, vol.274
, pp. 9984-9992
-
-
Lux, A.1
Attisano, L.2
Marchuk, D.A.3
-
17
-
-
21644461778
-
Crystal structure of BMP-9 and functional interactions with pro-region and receptors
-
Brown MA, Zhao Q, Baker KA, et al. Crystal structure of BMP-9 and functional interactions with pro-region and receptors. J Biol Chem. 2005;280:25111-25118.
-
(2005)
J Biol Chem
, vol.280
, pp. 25111-25118
-
-
Brown, M.A.1
Zhao, Q.2
Baker, K.A.3
-
18
-
-
0037085441
-
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
-
Korchynskyi O, ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem. 2002;277:4883-4891.
-
(2002)
J Biol Chem
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
ten Dijke, P.2
-
19
-
-
21644452716
-
Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex
-
Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CP, Bernabeu C. Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. J Cell Physiol. 2005;204:574-584.
-
(2005)
J Cell Physiol
, vol.204
, pp. 574-584
-
-
Blanco, F.J.1
Santibanez, J.F.2
Guerrero-Esteo, M.3
Langa, C.4
Vary, C.P.5
Bernabeu, C.6
-
20
-
-
8144230707
-
Endoglin promotes endothelial cell proliferation and TGFbeta/ALK1 signal transduction
-
Lebrin F, Goumans MJ, Jonker L, et al. Endoglin promotes endothelial cell proliferation and TGFbeta/ALK1 signal transduction. EMBO J. 2004;23:4018-4028.
-
(2004)
EMBO J
, vol.23
, pp. 4018-4028
-
-
Lebrin, F.1
Goumans, M.J.2
Jonker, L.3
-
21
-
-
0037114702
-
Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis
-
Lamouille S, Mallet C, Feige JJ, Bailly S. Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis. Blood. 2002;100:4495-4501.
-
(2002)
Blood
, vol.100
, pp. 4495-4501
-
-
Lamouille, S.1
Mallet, C.2
Feige, J.J.3
Bailly, S.4
-
22
-
-
25444529969
-
Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses
-
Mazerbourg S, Sangkuhl K, Luo CW, Sudo S, Klein C, Hsueh AJ. Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses. J Biol Chem. 2005;280:32122-32132.
-
(2005)
J Biol Chem
, vol.280
, pp. 32122-32132
-
-
Mazerbourg, S.1
Sangkuhl, K.2
Luo, C.W.3
Sudo, S.4
Klein, C.5
Hsueh, A.J.6
-
23
-
-
0036888627
-
Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells
-
Ota T, Fujii M, Sugizaki T, et al. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells. J Cell Physiol. 2002;193:299-318.
-
(2002)
J Cell Physiol
, vol.193
, pp. 299-318
-
-
Ota, T.1
Fujii, M.2
Sugizaki, T.3
-
24
-
-
31744451275
-
Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors
-
Wu X, Ma J, Han JD, Wang N, Chen YG. Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors. Microvasc Res. 2006;71:12-19.
-
(2006)
Microvasc Res
, vol.71
, pp. 12-19
-
-
Wu, X.1
Ma, J.2
Han, J.D.3
Wang, N.4
Chen, Y.G.5
-
25
-
-
33746998477
-
ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression
-
Lux A, Salway F, Dressman HK, et al. ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression. BMC Cardiovasc Disord. 2006;6:13.
-
(2006)
BMC Cardiovasc Disord
, vol.6
, pp. 13
-
-
Lux, A.1
Salway, F.2
Dressman, H.K.3
-
26
-
-
33745188200
-
Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells
-
Valdimarsdottir G, Goumans MJ, Itoh F, Itoh S, Heldin CH, ten Dijke P. Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells. BMC Cell Biol. 2006;7:16.
-
(2006)
BMC Cell Biol
, vol.7
, pp. 16
-
-
Valdimarsdottir, G.1
Goumans, M.J.2
Itoh, F.3
Itoh, S.4
Heldin, C.H.5
ten Dijke, P.6
-
27
-
-
0033534572
-
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily
-
Barbara NP, Wrana JL, Letarte M. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J Biol Chem. 1999;274:584-594.
-
(1999)
J Biol Chem
, vol.274
, pp. 584-594
-
-
Barbara, N.P.1
Wrana, J.L.2
Letarte, M.3
-
28
-
-
33748749625
-
Endoglin structure and function: Determinants of endoglin phosphorylation by TGFbeta receptors
-
Koleva RI, Conley BA, Romero D, et al. Endoglin structure and function: determinants of endoglin phosphorylation by TGFbeta receptors. J Biol Chem. 2006;281:25110-25123.
-
(2006)
J Biol Chem
, vol.281
, pp. 25110-25123
-
-
Koleva, R.I.1
Conley, B.A.2
Romero, D.3
-
29
-
-
0141656297
-
Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1
-
Foletta VC, Lim MA, Soosairajah J, et al. Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1. J Cell Biol. 2003;162:1089-1098.
-
(2003)
J Cell Biol
, vol.162
, pp. 1089-1098
-
-
Foletta, V.C.1
Lim, M.A.2
Soosairajah, J.3
-
30
-
-
0036340364
-
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels
-
Roman BL, Pham VN, Lawson ND, et al. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development. 2002;129:3009-3019.
-
(2002)
Development
, vol.129
, pp. 3009-3019
-
-
Roman, B.L.1
Pham, V.N.2
Lawson, N.D.3
-
31
-
-
0033757655
-
Arteriovenous malformations in mice lacking activin receptor-like kinase-1
-
Urness LD, Sorensen LK, Li DY. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000;26:328-331.
-
(2000)
Nat Genet
, vol.26
, pp. 328-331
-
-
Urness, L.D.1
Sorensen, L.K.2
Li, D.Y.3
-
32
-
-
0032973769
-
Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures
-
Ploemacher RE, Engels LJ, Mayer AE, Thies S, Neben S. Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures. Leukemia. 1999;13:428-437.
-
(1999)
Leukemia
, vol.13
, pp. 428-437
-
-
Ploemacher, R.E.1
Engels, L.J.2
Mayer, A.E.3
Thies, S.4
Neben, S.5
-
33
-
-
0029121286
-
Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation
-
Song JJ, Celeste AJ, Kong FM, Jirtle RL, Rosen V, Thies RS. Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation. Endocrinology. 1995;136:4293-4297.
-
(1995)
Endocrinology
, vol.136
, pp. 4293-4297
-
-
Song, J.J.1
Celeste, A.J.2
Kong, F.M.3
Jirtle, R.L.4
Rosen, V.5
Thies, R.S.6
-
34
-
-
0141516375
-
Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat
-
Li JZ, Li H, Sasaki T, et al. Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. Gene Ther. 2003;10:1735-1743.
-
(2003)
Gene Ther
, vol.10
, pp. 1735-1743
-
-
Li, J.Z.1
Li, H.2
Sasaki, T.3
-
35
-
-
0035159274
-
BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1
-
Majumdar MK, Wang E, Morris EA. BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1. J Cell Physiol. 2001;189:275-284.
-
(2001)
J Cell Physiol
, vol.189
, pp. 275-284
-
-
Majumdar, M.K.1
Wang, E.2
Morris, E.A.3
-
36
-
-
0039598632
-
Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9
-
Lopez-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK. Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9. Science. 2000;289:313-316.
-
(2000)
Science
, vol.289
, pp. 313-316
-
-
Lopez-Coviella, I.1
Berse, B.2
Krauss, R.3
Thies, R.S.4
Blusztajn, J.K.5
-
37
-
-
0037338037
-
An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis
-
Chen C, Grzegorzewski KJ, Barash S, et al. An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis. Nat Biotechnol. 2003;21:294-301.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 294-301
-
-
Chen, C.1
Grzegorzewski, K.J.2
Barash, S.3
-
38
-
-
0034674782
-
Bone morphogenetic protein-9: An autocrine/paracrine cytokine in the liver
-
Miller AF, Harvey SA, Thies RS, Olson MS. Bone morphogenetic protein-9: an autocrine/paracrine cytokine in the liver. J Biol Chem. 2000;275:17937-17945.
-
(2000)
J Biol Chem
, vol.275
, pp. 17937-17945
-
-
Miller, A.F.1
Harvey, S.A.2
Thies, R.S.3
Olson, M.S.4
-
39
-
-
33645786728
-
Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia
-
Letteboer TG, Mager JJ, Snijder RJ, et al. Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia. J Med Genet. 2006;43:371-377.
-
(2006)
J Med Genet
, vol.43
, pp. 371-377
-
-
Letteboer, T.G.1
Mager, J.J.2
Snijder, R.J.3
-
40
-
-
0032980052
-
Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily
-
Neuhaus H, Rosen V, Thies RS. Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily. Mech Dev. 1999;80:181-184.
-
(1999)
Mech Dev
, vol.80
, pp. 181-184
-
-
Neuhaus, H.1
Rosen, V.2
Thies, R.S.3
-
41
-
-
2042462926
-
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis
-
Chen H, Shi S, Acosta L, et al. BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development. 2004;131:2219-2231.
-
(2004)
Development
, vol.131
, pp. 2219-2231
-
-
Chen, H.1
Shi, S.2
Acosta, L.3
-
42
-
-
2542569364
-
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium
-
Stottmann RW, Choi M, Mishina Y, Meyers EN, Klingensmith J. BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development. 2004;131:2205-2218.
-
(2004)
Development
, vol.131
, pp. 2205-2218
-
-
Stottmann, R.W.1
Choi, M.2
Mishina, Y.3
Meyers, E.N.4
Klingensmith, J.5
-
43
-
-
33745318246
-
Distribution of ENG and ACVRL1 (ALK1) mutations in French HHT patients
-
Lesca G, Burnichon N, Raux G, et al. Distribution of ENG and ACVRL1 (ALK1) mutations in French HHT patients. Hum Mutat. 2006;27:598.
-
(2006)
Hum Mutat
, vol.27
, pp. 598
-
-
Lesca, G.1
Burnichon, N.2
Raux, G.3
|