Cleavage of chordin by xolloid metalloprotease suggests a role for proteolytic processing in the regulation of spemann organizer activity

Cell

Volumn 91, Issue 3, 1997, Pages 407-416

  Piccolo, Stefano ^a   Agius, Eric ^a   Lu, Bin ^a   Goodman, Shelley ^b   Dale, Leslie ^b   De Robertis, Eddy M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; MESSENGER RNA; METALLOPROTEINASE;

ANIMAL CELL; ARTICLE; DROSOPHILA; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GASTRULATION; MESODERM; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; XENOPUS;

ANIMALIA;

EID: 0030665807     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80424-9     Document Type: Article

References (45)

1. Biehs, B., François, V., and Bier, E. (1996). The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm. Genes Dev. 10, 2922-2934.
2. Childs, S.R., and O'Connor, M.B. (1994). Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic. Dev. Biol. 162, 209-220.
3. Dale, L, Howes, G., Price, B.M.J., and Smith, J.C. (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopusdevelopment. Development 115, 573-585.
4. De Robertis, E.M., and Sasai, Y. (1996). A common plan for dorsoventral patterning in Bilateria. Nature 380, 37-40.
5. Dosch, R., Gawantka, V., Delius, H., Blumestock, C., and Niehrs, C. (1997). Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus. Development 124, 2325-2334.
6. Fainsod, A., Steinbeisser, H., and De Robertis, E.M. (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13, 5015-5025.
7. Fainsod, A., Deissler, K., Yelin, R., Marom, K., Epstein, M., Pillemer, G., Steinbeisser, H., and Blum, M. (1997). The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4. Mech. Dev. 63, 39-50.
8. Ferguson, E.L., and Anderson, K.V. (1992a). Localized enhancement and repression of the activity of the TGF-β family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo. Development 114, 583-597.
9. Ferguson, E.L., and Anderson, K.V. (1992b). decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461.
10. Finelli, A.L., Bossie, C.A., Xie, T., and Padgett, R.W. (1994). Mutational analysis of the Drosophila tolloid gene, a human BMP-1 homolog. Development 120, 861-870.
11. François, V., and Bier, E. (1995). Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation. Cell 80, 19-20.
12. Goodman, S., Albano, R., Wardle, F., Matthews, G., Tannahill, D., and Dale, L. (1997). BMP1-related proteins promote the development of ventral mesoderm in early Xenopus embryos. Dev. Biol., in press.
13. Graft, J.M. (1997). Embryonic patterning: to BMP or not to BMP, that is the question. Cell 89, 171-174.
14. Graft, J.M., Scott Thies, R., Song, J.J., Celeste, A.J., and Melton, D.A. (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.
15. Hammerschmidt, M., Pelegri, F., Mullins, M.C., Kane, D.A., van Eeden, F.J.M., Granato, M., Brand, M., Furutani-Seiki, M., Haffter, P., Heisenberg, C.-P., et al. (1996a). dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. Development 123, 95-102.
16. Hammerschmidt, M., Serbedzija, G.N., and McMahon, A.P. (1996b). Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes Dev. 10, 2452-2461.
17. Harland, R.M. (1991). In situ hybridization: an improved whole-mount method for Xenopus embryos. Meth. Cell Biol. 36, 685-695.
18. Hazama, M., Aono, A., Ueno, N., and Fujisawa, Y. (1995). Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system. Biochem. Biophys. Res. Commun. 209, 859-866.
19. Hemmati-Brivanlou, A., and Melton, D. (1997). Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell 88, 13-17.
20. Hemmati-Brivanlou, A., and Thomsen, G.H. (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet. 17, 78-89.
21. Holley, S.A., Jackson, P.D., Sasai, Y., Lu, B., De Robertis, E.M., Hoffman, F.M., and Ferguson, E.L. (1995). A conserved system for dorsal-ventral patterning in insects and vertebrates involving short gastrulation and chordin. Nature 376, 249-253.
22. Holley, S.A., Neul, J.L., Attisano, L., Wrana, J.L., Sasai, Y., O'Connor, M.B., De Robertis, E.M., and Ferguson, E.L. (1996). The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor. Cell 86, 607-617.
23. Jones, C.M., Lyons, K.M., Lapan, P.M., Wright, C.V.E., and Hogan, B.L.M. (1992). DVR-4(Bone Morphogenetic Protein-4) as a posteriorventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.
24. Jürgens, G., Wieschaus, E., Nüsslein-Volhard, C., and Kluding, H. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. Roux's Arch. Dev. Biol. 193, 283-293.
25. Kessler, E., Takahara, K., Biniaminov, L., Brusel, M., and Greenspan, D.S. (1996). Bone morphogenetic protein-1: the type I procollagen C-proteinase. Science 271, 360-362.
26. Lin, J.J., Maeda, R., Ong, R.C., Kim, J., Lee, L.M., Kung, H.F., and Maéno, M. (1997). XBMP-1B (Xtld), a Xenopus homolog of the dorsoventral polarity gene in Drosophila, modifies tissue phenotypes of ventral explants. Dev. Growth Diff. 39, 43-51.
27. Maéno, M., Xue, Y., Wood, T.I., Ong, R.C., and Kung, H.F. (1993). Cloning and expression of cDNA encoding Xenopus laevis bone morphogenetic protein-1 during early embryonic development. Gene 134, 257-261.
28. Marqués, G., Musacchio, M., Shimell, M.J., Wünnenburg-Stapleton, K., Cho, K.W.Y., and O'Connor, M.B. (1997). Production of a Dpp activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins. Cell, this issue, 91, 417-426.
29. Moon, R.T., Brown, J.D., Yang-Snyder, J.A., and Miller, J.R. (1997). Structurally related receptors and antagonists compete for secreted Wnt ligands. Cell 88, 725-728.
30. Nishimatsu, S., Suzuki, A., Shoda, A., Murakami, K., and Ueno, N. (1992). Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos. Biochem. Biophys. Res. Commun. 184, 1487-1495.
31. Padgett, R.W., Wozney, J.M., and Gelbart, W.M. (1993). Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo. Proc. Natl. Acad. Sci. USA 90, 2905-2909.
32. Piccolo, S., Sasai, Y., Lu, B., and De Robertis, E.M. (1996). Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of Chordin to BMP-4. Cell 86, 589-598.
33. Sasai, Y., Lu, B., Steinbeisser, H., and De Robertis, E.M. (1995). Regulation of neural induction by the chd and BMP-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
34. Schulte-Merker, S., Lee, K.J., McMahon, A.P., and Hammerschmidt, M. (1997). The zebrafish organizer requires chordino. Nature 387, 862-863.
35. Shimell, M.J., Ferguson, E.L., Childs, S.R., and O'Connor, M.B. (1991). The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1. Cell 67, 469-481.
36. Stocker, W., Grams, F., Baumann, U., Reinemer, P., Gomis-Ruth, F.X., McKay, D.B., and Bode, W. (1995). The metzincins-topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zincpeptidases. Prot. Sci. 4, 823-840.
37. Suzuki, A., Scott Thies, R., Yamaji, N., Song, J.J., Wozney, J.M., Murakami, K., and Ueno, N. (1994). Atruncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl. Acad. Sci. USA 91, 10255-10259.
38. Suzuki, A., Kaneko, E., Maeda, J., and Ueno, N. (1997). Mesoderm induction by BMP-4 and -7 heterodimers. Biochem. Biophys. Res. Commun. 232, 153-156.
39. Suzuki, N., Labosky, P.A., Furuta, Y., Hargett, L., Dunn, R., Fogo, A.B., Takahara, K., Peters, D.M., Greenspan, D.S., and Hogan, B.L. (1996). Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid. Development 122, 3587-3595.
40. Takahara, K., Brevard, R., Hoffman, G.G., Suzuki, N., and Greenspan, D.S. (1996). Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1. Genomics 34, 157-165.
41. Wharton, K.A., Ray, R.P., and Gelbart, W.M. (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.
42. Wilson, P.A., and Hemmati-Brivanlou, A. (1995). Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333.
43. Wozney, J.M., Rosen, V., Celeste, A.J., Mitsock, L.M., Whitters, M.J., Kriz, R.W., Hewick, R.M., and Wang, E.A. (1988). Novel regulators of bone formation: molecular clones and activities. Science 242, 1528-1534.
44. Zimmerman, L.B., De Jesus-Escobar, J.M., and Harland, R.M. (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606.
45. Zusman, S.B., Sweeton, D., and Wieschaus, E.F. (1988). short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster. Dev. Biol. 129, 417-427.