Specific activin receptor-like kinase 3 inhibitors enhance liver regeneration

Journal of Pharmacology and Experimental Therapeutics

Volumn 351, Issue 3, 2014, Pages 549-558

  Tsugawa, Daisuke ^a   Oya, Yuki ^a   Masuzaki, Ryota ^a   Ray, Kevin ^a   Engers, Darren W ^b   Dib, Martin ^c   Do, Nhue ^c   Kuramitsu, Kaori ^d   Ho, Karen ^e   Frist, Audrey ^h   Yu, Paul B ^e   Bloch, Kenneth D ^f   Lindsley, Craig W ^b,g   Hopkins, Corey R ^c   Hong, Charles C ^h   Karp, Seth J ^a  

^a Vanderbilt University Transplant Center   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d KOBE UNIVERSITY   (Japan)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g VANDERBILT UNIVERSITY   (United States)

^h DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 [4 [3 (QUINOLIN 4 YL)PYRAZOLO[1,5 A]PYRIMIDIN 6 YL]PHENOXY]ETHYL]MORPHOLINE; 5 [6 (4 METHOXYPHENYL)PYRAZOLO[1,5 A]PYRIMIDIN 3 YL]QUINOLONE; 6 [4 (1 PIPERAZINYL)PHENYL] 3 (4 QUINOLINYL)PYRAZOLO[1,5 A]PYRIMIDINE; 7 (4 ISOPROPOXYPHENYL) 3 (1H PYRAZOL 4 YL)IMIDAZO[1,2 A]PYRIDINE; BILIRUBIN; BONE MORPHOGENETIC PROTEIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; DORSOMORPHIN; INTERLEUKIN 6; MESSENGER RNA; PROTEIN C JUN; PROTEIN P27; PROTEIN P53; PROTEIN SERINE THREONINE KINASE INHIBITOR; RETINOL BINDING PROTEIN 4; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; VASCULOTROPIN C; VU 0364849; VU 5350; BMPR1A PROTEIN, MOUSE; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; DRUG POTENTIATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INFANT; LIVER CELL; LIVER FUNCTION; LIVER MASS; LIVER METABOLISM; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; HUMANS; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; PROTEIN KINASE INHIBITORS;

EID: 84908290446     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.216903     Document Type: Article

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