Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis

Nature Medicine

Volumn 18, Issue 3, 2012, Pages 396-404

  Sugimoto, Hikaru ^a   LeBleu, Valerie S ^a   Bosukonda, Dattatreyamurty ^b   Keck, Peter ^b   Taduri, Gangadhar ^a   Bechtel, Wibke ^a   Okada, Hirokazu ^a   Carlson Jr , William ^b,c   Bey, Philippe ^c   Rusckowski, Mary ^d   Tampe, Björn ^e   Tampe, Desiree ^e   Kanasaki, Keizo ^a   Zeisberg, Michael ^a,e   Kalluri, Raghu ^a,e,f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN LIKE KINASE 3; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CAPTOPRIL; LIGAND; PEPTIDE DERIVATIVE; PHOSPHOTRANSFERASE; SMAD3 PROTEIN; THR 123; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; EPITHELIAL MESENCHYMAL TRANSITION; INFLAMMATION; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY REGENERATION; KIDNEY TUBULE EPITHELIUM; MOUSE; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; TISSUE REGENERATION; TREATMENT RESPONSE;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; APOPTOSIS; BONE MORPHOGENETIC PROTEIN RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CAPTOPRIL; DIABETIC NEPHROPATHIES; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; INFLAMMATION; KIDNEY; KIDNEY TUBULES; MICE; PEPTIDE LIBRARY; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; REGENERATION; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 84858008133     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2629     Document Type: Article

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