Applications of small molecule BMP inhibitors in physiology and disease

Cytokine and Growth Factor Reviews

Volumn 20, Issue 5-6, 2009, Pages 409-418

  Hong, Charles C ^a   Yu, Paul B ^b  

^a Center for Inherited Heart Disease   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Anemia; Bone mineral density; Bone morphogenetic protein; Cardiomyocyte; Embryonic stem cell; Fibrodysplasia ossificans progressiva; Hepcidin; High throughput screen; TGF

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN RECEPTOR 1; ACTIVIN RECEPTOR 2; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN INHIBITOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; CHORDIN; DORSOMORPHIN; FOLLISTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IRON; LDN 193189; NOGGIN; PROTEIN INHIBITOR; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

BONE METABOLISM; BONE REGENERATION; BONE REMODELING; CELL DIFFERENTIATION; CELL FATE; CELL GROWTH; CELL MANIPULATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG STABILITY; DRUG STRUCTURE; EMBRYO PATTERN FORMATION; ENZYME INHIBITION; GASTRULATION; GENE TRANSFER; HETEROTOPIC OSSIFICATION; HIGH THROUGHPUT SCREENING; HISTOGENESIS; HOMEOSTASIS; HUMAN; IRON BALANCE; NONHUMAN; ORGANOGENESIS; OSSIFICATION; OSSIFYING MYOSITIS; PRIORITY JOURNAL; RECEPTOR BLOCKING; REVIEW; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL TRANSPLANTATION; ZEBRA FISH;

ANIMALS; BONE DISEASES; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEINS; CELL PHYSIOLOGICAL PHENOMENA; EMBRYO, NONMAMMALIAN; HUMANS; MODELS, BIOLOGICAL; OSTEOGENESIS; PYRAZOLES; PYRIMIDINES; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; ZEBRAFISH;

EID: 70849128432     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2009.10.021     Document Type: Review

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