Three-dimensional structure of recombinant human osteogenic protein 1: Structural paradigm for the transforming growth factor β superfamily

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 2, 1996, Pages 878-883

  Griffith, Diana L ^a,d   Keck, Peter C ^b   Sampath, T Kuber ^b   Rueger, David C ^b   Carlson, William D ^c  

^a BRANDEIS UNIVERSITY   (United States)

^b CURIS INC   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

bone morphogenetic protein; cystine knot; protein structure; receptor binding model; x ray crystallography

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; EMBRYO DEVELOPMENT; HUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

BASE SEQUENCE; BONE MORPHOGENETIC PROTEINS; CRYSTALLOGRAPHY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030042590     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.2.878     Document Type: Article

References (40)

1. Sampath, T. K., Coughlin, J. E., Whetstone, R. M., Banach, D., Corbett, C., Ridge, R. J., Özkaynak, E., Oppermann, H. & Rueger, D. C. (1990) J. Biol. Chem. 265, 13198-13205.
2. Cook, S. D., Wolfe, M. W., Salkeld, S. L. & Rueger, D. C. (1995) J. Bone Joint Surg. 77A, 734-750.
3. Özkaynak, E., Schnegelsberg, P. N. J. & Oppermann, H. (1991) Biochem. Biophys. Res. Commun. 179, 116-123.
4. Helder, M. N., Özkaynak, E., Sampath, K. T., Luyten, F. P., Latin, V., Oppermann, H. & Vukicevic, S. (1995) J. Histochem. Cytochem. 43, 1035-1044.
5. Perides, G., Jensen, F. E., Edgecomb, P., Rueger, D. C. & Charness, M. E. (1995) Neurosci. Lett. 187, 21-24.
6. Lefer, A. M., Psau, P. S., Ma, X.-L. & Sampath, T. K. (1992) J. Mol. Cell. Cordiol. 24, 585-593.
7. Kingsley, D. (1994) Genes Dev. 8, 133-146.
8. Daopin, S., Piez, K. A., Ogawa, Y. & Davies, D. R. (1992) Science 257, 369-373.
9. Schlunegger, M. & Grütier, M. (1992) Nature (London) 358, 430-434.
10. Özkaynak, E., Rueger, D. C., Drier, E. A., Corbett, C., Ridge, R. J., Sampath, K. T. & Oppermann, H. (1990) EMBO J. 9, 2085-2093.
11. Sampath, K. T., Maliakal, J. C., Hsuschka, T., Jones, W. K., Sask, H., Tucker, R. F., White, K. H., Coughlin, J. E., Tucker, M. M., Pang, R. H. L., Corbett, C., Özkaynak, E., Oppermann, H. & Rueger, D. C. (1992) J. Biol. Chem. 267, 20352-20362.
12. Griffith, D. L., Oppermann, H., Rueger, D. C., Sampath, T. K., Tucker, R. F. & Carlson, W. D. (1994) J. Mol. Biol. 244, 657-658.
13. Higashi, T. (1990) R-AXIS-IIC, A Program for Indexing and Processing R-AXIS IIC Imaging Plate Data (Rigaku, Danvers, MA).
14. Collaborative Computation Project (1994) Acta Crystallogr. D 50, 760-763.
15. Ten Eyck, L. F. & Arnone, A. (1976) J. Mol. Biol. 100, 3-11.
16. Wang, B. C. (1985) Methods Enzymol. 115, 90-112.
17. Reed, R. J. (1986) Acta Crystallogr. A 42, 140-149.
18. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, N. (1991) Acta Crystallogr. A 47, 110-119.
19. Brunger, A. T., Kuriyan, J. & Karplus, M. (1987) Science 235, 458-460.
20. Lee, B. & Richards, F. M. (1971) J. Mol. Biol. 55, 379-400.
21. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, E. F., Brice, M. D., Rodgers, J. R., Kennard, O., Shimanouchi, T. & Tasumi, M. (1977) J. Mol. Biol. 112, 535-542.
22. Gilson, M. K. & Honig, B. H. (1987) Nature (London) 330, 84-86.
23. Nicholls, A. & Honig, B. (1991) J. Comput. Chem. 12, 435-445.
24. McDonald, N. Q. & Hendrickson, W. A. (1993) Cell 73, 421-424.
25. Oefner, C., D'Arcy, A., Winkler, F. K., Eggimann, B. & Hosang, M. (1992) EMBO J. 11, 3921-3926.
26. Lapthorn, A. J., Harris, D. C., Litlejohn, A., Lustbader, J. W., Canfield, R. E., Machin, K. J., Morgan, F. J. & Isaacs, N. W. (1994) Nature (London) 369, 455-461.
27. Wu, H., Lustbader, J. W., Liu, Y., Canfield, R. E. & Hendrickson, W. A. (1994) Structure Curr. Biol. 2, 545-558.
28. Leszczynski, J. F. & Rose, G. D. (1986) Science 234, 849-855.
29. Sibanda, B. L. & Thornton, J. M. (1991) Methods Enzymol. 202, 59-82.
30. McDonald, N. Q., Lapatto, R., Murray-Rust, J., Gunning, J., Wlodawer, A. & Blundell, T. L. (1991) Nature (London) 354, 411-414.
31. Stenzel, P., Angerer, L. M., Smith, B. J., Angerer, R. C. & Vale, W. W. (1994) Dev. Biol. 166, 149-158.
32. Arora, K., Levine, M. S. & O'Connor, M. B. (1994) Genes Dev. 8, 2588-2601.
33. Wozney, J. M. & Celeste, A. (1993) Eur. Patent Appl. WO 93/00432, seq. id. no. 9.
34. Celeste, A. & Wozney, J. M. (1994) Eur. Patent Appl. WO 94/26893, seq. id. no. 1.
35. Storm, E. E., Huynh, T. V., Copeland, N. G., Jenkins, N. A., Kingsley, D. M. & Lee, S. J. (1994) Nature (London) 368, 639-643.
36. Chang, S. C., Hoang, B., Thomas, J. T., Vukicevic, S., Luyten, F. P., Ryba, N. J. P., Kozak, C. A., Reddi, A. R. & Moos, M. (1994) J. Biol. Chem. 269, 28227-28234.
37. Özkaynak, E. & Oppermann, H. (1994) Eur. Patent Appl. WO 94/10203, seq. id. no. 1.
38. Hötten, G., Neifhardt, H., Schneider, C. & Pohl, J. (1995) Biochem. Biophys. Res. Commun. 206, 608-613.
39. Cunningham, N. S., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Reddi, A. H. & Lee, S.-J. (1995) Growth Factors 12, 99-109.
40. Massague, J., Attisano, L. & Wrana, J. L. (1994) Trends Cell Biol. 4, 172-178.