Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo- 3-phenylpropan-2-yl)carbamoyl)benzoic acid analogues as BMP-2 stimulators

Journal of Medicinal Chemistry

Volumn 55, Issue 19, 2012, Pages 8248-8259

  Balaramnavar, Vishal M ^a   Khan, Imran A ^a   Siddiqui, Jawed Akhtar ^a   Khan, Mohd Parvez ^a   Chakravarti, Bandana ^a   Sharan, Kunal ^a   Swarnkar, Gaurav ^a   Rastogi, Namrata ^a   Siddiqui, H H ^b   Mishra, Durga Prasad ^a   Chattopadhyay, Naibedya ^a   Saxena, Anil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INTEGRAL UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2((1((2 (BENZOYLOXY) 2 PHENYLETHYL) (BENZYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL) BENZOIC ACID; 2((1((2 (BENZYLOXY) 2 PHENYLETHYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL) BENZOIC ACID; 2((1((2 ACETOXY 2 PHENYLETHYL) (BENZYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL) BENZOIC ACID; 2[(1 (BENZYL (2 (BENZYLOXY) 2 PHENYLETHYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL] BENZOIC ACID; 2[(1 (BENZYL (2 CYANO 2 PHENYLETHYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL] BENZOIC ACID; 2[(1 (BENZYL (2 HYDROXY 2 PHENYLETHYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL] BENZOIC ACID; 2[(1 (BENZYL (2 PHENYL 2 (TOSYLOXY) ETHYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL] BENZOIC ACID; 2[(1 OXO 1 (PHENETHYLAMINO) 3 PHENYLPROPAN 2 YL) CARBAMOYL] BENZOIC ACID; 2[(1 OXO 3 PHENYL 1 ((2 PHENYL 2 (TOSYLOXY) ETHYL) AMINO) PROPAN 2 YL) CARBAMOYL] BENZOIC ACID; 2[(1((2 ACETOXY 2 PHENYLETHYL) AMINO) 1 OXO 3 PHENYLPROPAN 2 YL) CARBAMOYL] BENZOIC ACID; BORTEZOMIB; NOGGIN; PROTEASOME; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; FRACTURE; FRACTURE HEALING; MALE; NONHUMAN; OSSIFICATION; OSTEOBLAST; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; FRACTURE HEALING; FRACTURES, BONE; OSTEOBLASTS; OSTEOGENESIS; PHENYLALANINE; PHTHALIC ACIDS; PROTEASOME INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84867350005     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300985d     Document Type: Article

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