Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary Artery smooth muscle cells

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 24443-24450

  Yu, Paul B ^a   Beppu, Hideyuki ^a   Kawai, Noriko ^a   Li, En ^a,b   Blocht, Kenneth D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; BONE; CELLS; ENZYME KINETICS; MUSCLE; RESPIRATORY SYSTEM;

BMP RECEPTORS; BONE MORPHOGENIC PROTEINS (BMP); MITOGEN; PULMUNARY HYPERTENSION;

PROTEINS;

ACTIVIN RECEPTOR 1; ACTIVIN RECEPTOR 2; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOGENIC PROTEIN 1; RECEPTOR SUBTYPE; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE EXPRESSION; KNOCKOUT MOUSE; LIGAND BINDING; MALE; MOLECULAR RECOGNITION; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE II; ALLELES; ANIMALS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE DELETION; HETEROZYGOTE; LIGANDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MUTATION; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PULMONARY ARTERY; RNA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 21644447416     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502825200     Document Type: Article

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