BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

Journal of Cell Science

Volumn 120, Issue 6, 2007, Pages 964-972

  Scharpfenecker, Marion ^a   van Dinther, Maarten ^a   Liu, Zhen ^a   van Bezooijen, Rutger L ^a   Zhao, Qinghai ^b,c   Pukac, Laurie ^b,c   Löwik, Clemens W G M ^a   ten Dijke, Peter ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GLAXOSMITHKLINE   (United States)

^c Drug Development   (United States)

Author keywords

ALK1; Angiogenesis; bFGF; BMP; Endoglin; Signalling; Smad; VEGF

Indexed keywords

ACTIVIN RECEPTOR 1; ACTIVIN RECEPTOR 2; BASIC FIBROBLAST GROWTH FACTOR; BONE MORPHOGENETIC PROTEIN 9; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; ENDOGLIN; INHIBITOR OF DIFFERENTIATION 1; MESSENGER RNA; SMAD1 PROTEIN; SMAD5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FETUS; GENE EXPRESSION; GENETIC TRANSFECTION; GROWTH REGULATION; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; TUMOR CELL; VASCULAR ENDOTHELIUM;

ACTIVIN RECEPTORS, TYPE I; ACTIVIN RECEPTORS, TYPE II; ANIMALS; BONE MORPHOGENETIC PROTEINS; CATTLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

BOVINAE; MUS;

EID: 34247331476     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.002949     Document Type: Article

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