Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis

Genes to Cells

Volumn 7, Issue 9, 2002, Pages 949-960

  Katagiri, Takenobu ^a,d   Imada, Mana ^a   Yanai, Takeshi ^a,d   Suda, Tatsuo ^b   Takahashi, Naoyuki ^c   Kamijo, Ryutaro ^a  

^a SHOWA UNIVERSITY   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c MATSUMOTO DENTAL UNIVERSITY   (Japan)

^d TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR; CYSTEINE; DEOXYRIBONUCLEOPROTEIN; GLYCINE; MESSENGER RNA; SMAD PROTEIN; SMAD1 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENETIC IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; MUSCLE DEVELOPMENT; MYOBLAST; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEINS; CELL LINE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; GENES, REPORTER; HELIX-LOOP-HELIX MOTIFS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, GROWTH FACTOR; REPRESSOR PROTEINS; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; SMAD PROTEINS; SMAD1 PROTEIN; SMAD4 PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 0036732838     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.2002.00573.x     Document Type: Article

References (70)

1. Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts
2. Muscle differentiation: More complexity to the network of myogenic regulators
3. Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria
4. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
5. Skeletal muscle formation in vertebrates
6. Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone
7. Bone morphogenetic protein 2 (BMP-2) induces sequential changes of Id gene expression in the breast cancer cell line MCF-7
8. Direct binding of Smad3 and Smad4 to critical TGF β-inducible elements in the promoter of human plasminogen inhibitor-type 1 gene
9. Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation
10. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation
11. Poles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation
12. OAZ. uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways
13. The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
14. Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
15. Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells
16. Smad6 inhibits signaling by the TGF-β superfamily
17. Smad6 is a Smad1/5-induced Smad inhibitor: Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter
18. Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2
19. TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
20. Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-b, activin, and bone morphogenetic protein-inducible enhancer
21. Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogepin
22. The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2
23. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
24. Signal transduction by bone morphogenetic proteins
25. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
26. The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
27. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF β superfamily
28. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific responses elements in the Id1 promoter
29. Direct binding of Smad1 and Smad4 to two distinct motifs mediated bone morphogenetic protein-specific transcriptional activation of Id1 gene
30. Transcription factor families: Muscling in on the myogenic program
31. Purification and partial amino, acid sequence of osteogenin, a protein initiating bone differentiation
32. A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: Roles of animal pole tissue in the development of ventral mesoderm
33. How cells read TGF-β signals
34. Controlling TGF-β signaling
35. Signal transduction by bone morphogenetic protein receptors: Functional roles of Smad proteins
36. Combinational control of muscle development by basic helix-loop-helix and MADS-box transcription factors
37. Identification of Smad7, a TGF β-inducible antagonist of TGF-β signaling
38. A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts
39. Role of p300, a transcriptional coactivator, in signaling of TGF-β
40. Smad5 and DPC4 are key Molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12
41. Molecular mechanisms regulating myogenic determination and differentiation
42. Physical and functional interaction of SMADs and p300/CBP
43. TGF-β family signal transduction in Drosophila development
44. Bone morphogenetic proteins: From basic to clinical applications
45. Bone morphogenctic proteins; from basic studies to clinical approaches
46. Bovine osteogenic protein is composed of dimmers of OP-1 and BMP-2A, two members of the transforming growth factor-β superfamily
47. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro
48. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
49. DPC4 gene in various tumor types
50. Structural insights on Smad function in TGF-β signaling
51. Crystal structure of a Smad1 MH1 domain bound to DNA: Insights on DNA-binding in TGF-β signaling
52. Limb alterations in brachypodism mice due to mutations in a new member of the TGF β-superfamily
53. A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo
54. MyoD and the regulation of myogenesis by helix-loop-helix proteins
55. Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1
56. A human chondrodysplasia due to a mutation in a TGF-β superfamily member
57. CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells
58. Transcription ofthe dominant-negative helix-loop-helix protein Id1 is regulated by a protein complex containing the immediate-early response gene Egr-1
59. Bone: Formation by autoinduction
60. Inhibition of P13K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2
61. GS domain mutations that constitutively active TβR-1, the downstream signaling component in theTGF-β receptor complex
62. Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair
63. Novel regulators of bone formation: Molecular clones and activities
64. Regulation of Smad activity
65. Mechanism of activation of the TGF-β receptor
66. Smad proteins act in combination with synergistic and antagonistic regulators to target DPP responses to the Drosophila mesoderm
67. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
68. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
69. Smad1 and Smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts
70. Expression of mouse osteocalcin transcripts, OG1 and OG2, is differently regulated in bone tissue and osteoblast cultures