메뉴 건너뛰기




Volumn 116, Issue 1, 2006, Pages 70-79

Uterine sensitization-associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; NEUTRALIZING ANTIBODY; OSTEOGENIC PROTEIN 1; PROTEIN INHIBITOR; SMAD PROTEIN;

EID: 31044453402     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI25445     Document Type: Article
Times cited : (125)

References (49)
  • 1
    • 0030419494 scopus 로고    scopus 로고
    • Molecular insights into renal interstitial fibrosis
    • Eddy, A.A. 1996. Molecular insights into renal interstitial fibrosis. J. Am. Soc. Nephrol. 7:2495-2508.
    • (1996) J. Am. Soc. Nephrol. , vol.7 , pp. 2495-2508
    • Eddy, A.A.1
  • 2
    • 0032753718 scopus 로고    scopus 로고
    • Tubular epithelial cells: A critical cell type in the regulation of renal inflammatory processes
    • van Kooten, C., Daha, M.R., and van Es, L.A. 1999. Tubular epithelial cells: a critical cell type in the regulation of renal inflammatory processes. Exp. Nephrol. 7:429-437.
    • (1999) Exp. Nephrol. , vol.7 , pp. 429-437
    • Kooten, C.1    Daha, M.R.2    Van Es, L.A.3
  • 3
    • 17644396635 scopus 로고    scopus 로고
    • Setting a trap for tissue fibrosis
    • Neilson, E.G. 2005. Setting a trap for tissue fibrosis. Nat. Med. 11:373-374.
    • (2005) Nat. Med. , vol.11 , pp. 373-374
    • Neilson, E.G.1
  • 4
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg, M., et al. 2003. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat. Med. 9:964-968.
    • (2003) Nat. Med. , vol.9 , pp. 964-968
    • Zeisberg, M.1
  • 5
    • 0032128140 scopus 로고    scopus 로고
    • Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat
    • Vukicevic, S., et al. 1998. Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat. J. Clin. Invest. 102:202-214.
    • (1998) J. Clin. Invest. , vol.102 , pp. 202-214
    • Vukicevic, S.1
  • 6
    • 17544379605 scopus 로고    scopus 로고
    • Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction
    • Hruska, K.A., et al. 2000. Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction. Am. J. Physiol. Renal. Physiol. 279:F130-F143.
    • (2000) Am. J. Physiol. Renal. Physiol. , vol.279
    • Hruska, K.A.1
  • 7
    • 0036238022 scopus 로고    scopus 로고
    • Treatment of chronic tubulointerstitial disease: A new concept
    • Hruska, K.A. 2002. Treatment of chronic tubulointerstitial disease: a new concept. Kidney Int. 61:1911-1922.
    • (2002) Kidney Int. , vol.61 , pp. 1911-1922
    • Hruska, K.A.1
  • 8
    • 0242582117 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
    • Zeisberg, M., et al. 2003. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am. J. Physiol. Renal. Physiol. 285:F1060-F1067.
    • (2003) Am. J. Physiol. Renal. Physiol. , vol.285
    • Zeisberg, M.1
  • 9
    • 0028832707 scopus 로고
    • A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
    • Dudley, A.T., Lyons, K.M., and Robertson, E.J. 1995. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 9:2795-2807.
    • (1995) Genes Dev. , vol.9 , pp. 2795-2807
    • Dudley, A.T.1    Lyons, K.M.2    Robertson, E.J.3
  • 10
    • 0028882261 scopus 로고
    • BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
    • Luo, G., et al. 1995. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev. 9:2808-2820.
    • (1995) Genes Dev. , vol.9 , pp. 2808-2820
    • Luo, G.1
  • 11
    • 0025362715 scopus 로고
    • OP-1 cDNA encodes an osteogenic protein in the TGF-beta family
    • Ozkaynak, E., et al. 1990. OP-1 cDNA encodes an osteogenic protein in the TGF-beta family. EMBO J. 9:2085-2093.
    • (1990) EMBO J. , vol.9 , pp. 2085-2093
    • Ozkaynak, E.1
  • 12
    • 0036149123 scopus 로고    scopus 로고
    • BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells
    • Gould, S.E., Day, M., Jones, S.S., and Dorai, H. 2002. BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells. Kidney Int. 61:51-60.
    • (2002) Kidney Int. , vol.61 , pp. 51-60
    • Gould, S.E.1    Day, M.2    Jones, S.S.3    Dorai, H.4
  • 13
    • 0032922119 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney
    • Simon, M., et al. 1999. Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney. Am. J. Physiol. 276:F382-F389.
    • (1999) Am. J. Physiol. , vol.276
    • Simon, M.1
  • 14
    • 0034758712 scopus 로고    scopus 로고
    • Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy
    • Wang, S.N., Lapage, J., and Hirschberg, R. 2001. Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy. J. Am. Soc. Nephrol. 12:2392-2399.
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 2392-2399
    • Wang, S.N.1    Lapage, J.2    Hirschberg, R.3
  • 15
    • 0036143995 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7: An anti-fibrotic morphogenetic protein with therapeutic importance in renal disease
    • Lund, R.J., Davies, M.R., and Hruska, K.A. 2002. Bone morphogenetic protein-7: an anti-fibrotic morphogenetic protein with therapeutic importance in renal disease. Curr. Opin. Nephrol. Hypertens. 11:31-36.
    • (2002) Curr. Opin. Nephrol. Hypertens , vol.11 , pp. 31-36
    • Lund, R.J.1    Davies, M.R.2    Hruska, K.A.3
  • 16
    • 0031903255 scopus 로고    scopus 로고
    • Osteogenic protein-1 mRNA expression is selectively modulated after acute ischemic renal injury
    • Almanzar, M.M., et al. 1998. Osteogenic protein-1 mRNA expression is selectively modulated after acute ischemic renal injury. J. Am. Soc. Nephrol. 9:1456-1463.
    • (1998) J. Am. Soc. Nephrol. , vol.9 , pp. 1456-1463
    • Almanzar, M.M.1
  • 17
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-beta signaling
    • Massague, J., and Chen, Y.G. 2000. Controlling TGF-beta signaling. Genes Dev. 14:627-644.
    • (2000) Genes Dev. , vol.14 , pp. 627-644
    • Massague, J.1    Chen, Y.G.2
  • 18
    • 0036838737 scopus 로고    scopus 로고
    • Uterine sensitization-associated gene-1: A novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction
    • Simmons, D.G., and Kennedy, T.G. 2002. Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction. Biol. Reprod. 67:1638-1645.
    • (2002) Biol. Reprod. , vol.67 , pp. 1638-1645
    • Simmons, D.G.1    Kennedy, T.G.2
  • 19
    • 0347916881 scopus 로고    scopus 로고
    • Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists
    • Avsian-Kretchmer, O., and Hsueh, A.J. 2004. Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists. Mol. Endocrinol. 18:1-12.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 1-12
    • Avsian-Kretchmer, O.1    Hsueh, A.J.2
  • 20
    • 0242521297 scopus 로고    scopus 로고
    • Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
    • Laurikkala, J., Kassai, Y., Pakkasjarvi, L., Thesleff, I., and Itoh, N. 2003. Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev. Biol. 264:91-105.
    • (2003) Dev. Biol. , vol.264 , pp. 91-105
    • Laurikkala, J.1    Kassai, Y.2    Pakkasjarvi, L.3    Thesleff, I.4    Itoh, N.5
  • 21
    • 12144290334 scopus 로고    scopus 로고
    • USAG1: A bone morphogenetic protein antagonist abundantly expressed in the kidney
    • Yanagita, M., et al. 2004. USAG1: a bone morphogenetic protein antagonist abundantly expressed in the kidney. Biochem. Biophys. Res. Commun. 316:490-500.
    • (2004) Biochem. Biophys. Res. Commun. , vol.316 , pp. 490-500
    • Yanagita, M.1
  • 22
    • 0036738495 scopus 로고    scopus 로고
    • Cancer therapy and renal injury
    • doi:10.1172/JCI200216568
    • Schrier, R.W. 2002. Cancer therapy and renal injury. J. Clin. Invest. 110:743-745. doi:10.1172/JCI200216568.
    • (2002) J. Clin. Invest. , vol.110 , pp. 743-745
    • Schrier, R.W.1
  • 23
    • 0032519006 scopus 로고    scopus 로고
    • Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure
    • Megyesi, J., Safirstein, R.L., and Price, P.M. 1998. Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure. J. Clin. Invest. 101:777-782.
    • (1998) J. Clin. Invest. , vol.101 , pp. 777-782
    • Megyesi, J.1    Safirstein, R.L.2    Price, P.M.3
  • 24
    • 0036738517 scopus 로고    scopus 로고
    • TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity
    • doi:10.1172/JCI200215606
    • Ramesh, G., and Reeves, W.B. 2002. TNF-á mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity. J. Clin. Invest. 110:835-842. doi:10.1172/JCI200215606.
    • (2002) J. Clin. Invest. , vol.110 , pp. 835-842
    • Ramesh, G.1    Reeves, W.B.2
  • 25
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang, J., and Liu, Y. 2001. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am. J. Pathol. 159:1465-1475.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 27
    • 0032808256 scopus 로고    scopus 로고
    • Molecular and cellular pathophysiology of obstructive nephropathy
    • Chevalier, R.L. 1999. Molecular and cellular pathophysiology of obstructive nephropathy. Pediatr. Nephrol. 13:612-619.
    • (1999) Pediatr. Nephrol. , vol.13 , pp. 612-619
    • Chevalier, R.L.1
  • 28
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • doi:10.1172/JCI200319270
    • Sato, M., Muragaki, Y., Saika, S., Roberts, A.B., and Ooshima, A. 2003. Targeted disruption of TGFbeta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J. Clin. Invest. 112:1486-1494. doi:10.1172/JCI200319270.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 29
    • 0346724511 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition and its implications for fibrosis
    • doi:10.1172/JCI200320530
    • Kalluri, R., and Neilson, E.G. 2003. Epithelialmesenchymal transition and its implications for fibrosis. J. Clin. Invest. 112:1776-1784. doi:10.1172/ JCI200320530.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 30
    • 0036786834 scopus 로고    scopus 로고
    • TGF-beta signaling in renal disease
    • Bottinger, E.P., and Bitzer, M. 2002. TGF-beta signaling in renal disease. J. Am. Soc. Nephrol. 13:2600-2610.
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 2600-2610
    • Bottinger, E.P.1    Bitzer, M.2
  • 31
    • 0036322007 scopus 로고    scopus 로고
    • Evidence that fibroblasts derive from epithelium during tissue fibrosis
    • doi:10.1172/JCI200215518
    • Iwano, M., et al. 2002. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J. Clin. Invest. 110:341-350. doi:10.1172/JCI200215518.
    • (2002) J. Clin. Invest. , vol.110 , pp. 341-350
    • Iwano, M.1
  • 32
    • 14844290237 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
    • Zeisberg, M., Shah, A.A., and Kalluri, R. 2005. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J. Biol. Chem. 280:8094-8100.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8094-8100
    • Zeisberg, M.1    Shah, A.A.2    Kalluri, R.3
  • 33
    • 0031892511 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 regulates chemokine and complement production by human proximal tubular epithelial cells
    • Gerritsma, J.S., van Kooten, C., Gerritsen, A.F., van Es, L.A., and Daha, M.R. 1998. Transforming growth factor-beta 1 regulates chemokine and complement production by human proximal tubular epithelial cells. Kidney Int. 53:609-616.
    • (1998) Kidney Int. , vol.53 , pp. 609-616
    • Gerritsma, J.S.1    Van Kooten, C.2    Gerritsen, A.F.3    Van Es, L.A.4    Daha, M.R.5
  • 35
    • 20844462829 scopus 로고    scopus 로고
    • Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome
    • Davies, M.R., Lund, R.J., Mathew, S., and Hruska, K.A. 2005. Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome. J. Am. Soc. Nephrol. 16:917-928.
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 917-928
    • Davies, M.R.1    Lund, R.J.2    Mathew, S.3    Hruska, K.A.4
  • 36
    • 0036223869 scopus 로고    scopus 로고
    • Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7
    • Gonzalez, E.A., et al. 2002. Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7. Kidney Int. 61:1322-1331.
    • (2002) Kidney Int. , vol.61 , pp. 1322-1331
    • Gonzalez, E.A.1
  • 37
    • 0942290527 scopus 로고    scopus 로고
    • Kidney-bone, bone-kidney, and cell-cell communications in renal osteodystrophy
    • Hruska, K.A., et al. 2004. Kidney-bone, bone-kidney, and cell-cell communications in renal osteodystrophy. Semin. Nephrol. 24:25-38.
    • (2004) Semin. Nephrol. , vol.24 , pp. 25-38
    • Hruska, K.A.1
  • 38
    • 0942287106 scopus 로고    scopus 로고
    • Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model
    • Lund, R.J., Davies, M.R., Brown, A.J., and Hruska, K.A. 2004. Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model. J. Am. Soc. Nephrol. 15:359-369.
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 359-369
    • Lund, R.J.1    Davies, M.R.2    Brown, A.J.3    Hruska, K.A.4
  • 39
    • 21344443319 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in development and homeostasis of kidney
    • Simic, P., and Vukicevic, S. 2005. Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev. 16:299-308.
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 299-308
    • Simic, P.1    Vukicevic, S.2
  • 40
    • 0037835949 scopus 로고    scopus 로고
    • BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure
    • Davies, M.R., Lund, R.J., and Hruska, K.A. 2003. BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. J. Am. Soc. Nephrol. 14:1559-1567.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1559-1567
    • Davies, M.R.1    Lund, R.J.2    Hruska, K.A.3
  • 41
    • 22744434737 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in vascular calcification
    • Hruska, K.A., Mathew, S., and Saab, G. 2005. Bone morphogenetic proteins in vascular calcification. Circ. Res. 97:105-114.
    • (2005) Circ. Res. , vol.97 , pp. 105-114
    • Hruska, K.A.1    Mathew, S.2    Saab, G.3
  • 42
    • 0031667009 scopus 로고    scopus 로고
    • Regulation of BMP7 expression during kidney development
    • Godin, R.E., Takaesu, N.T., Robertson, E.J., and Dudley, A.T. 1998. Regulation of BMP7 expression during kidney development. Development. 125:3473-3482.
    • (1998) Development , vol.125 , pp. 3473-3482
    • Godin, R.E.1    Takaesu, N.T.2    Robertson, E.J.3    Dudley, A.T.4
  • 43
    • 4243180526 scopus 로고    scopus 로고
    • Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
    • Michos, O., et al. 2004. Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development. 131:3401-3410.
    • (2004) Development , vol.131 , pp. 3401-3410
    • Michos, O.1
  • 44
    • 0141725483 scopus 로고    scopus 로고
    • Wise, a context-dependent activator and inhibitor of Wnt signalling
    • Itasaki, N., et al. 2003. Wise, a context-dependent activator and inhibitor of Wnt signalling. Development. 130:4295-4305.
    • (2003) Development , vol.130 , pp. 4295-4305
    • Itasaki, N.1
  • 45
    • 17644378679 scopus 로고    scopus 로고
    • Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
    • Lin, J., et al. 2005. Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat. Med. 11:387-393.
    • (2005) Nat. Med. , vol.11 , pp. 387-393
    • Lin, J.1
  • 46
    • 0036950667 scopus 로고    scopus 로고
    • Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis
    • doi:10.1172/JCI200215045
    • Nishida, M., et al. 2002. Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis. J. Clin. Invest. 110:1859-1868. doi:10.1172/JCI200215045.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1859-1868
    • Nishida, M.1
  • 47
    • 0035074233 scopus 로고    scopus 로고
    • Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis
    • Yanagita, M., et al. 2001. Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis. Am. J. Pathol. 158:1423-1432.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1423-1432
    • Yanagita, M.1
  • 48
    • 0347336379 scopus 로고    scopus 로고
    • Gas6 induces mesangial cell proliferation via latent transcription factor STAT3
    • Yanagita, M., et al. 2001. Gas6 induces mesangial cell proliferation via latent transcription factor STAT3. J. Biol. Chem. 276:42364-42369.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42364-42369
    • Yanagita, M.1
  • 49
    • 0036076461 scopus 로고    scopus 로고
    • Essential role of Gas6 for glomerular injury in nephrotoxic nephritis
    • doi:10.1172/JCI200214861
    • Yanagita, M., et al. 2002. Essential role of Gas6 for glomerular injury in nephrotoxic nephritis. J. Clin. Invest. 110:239-246. doi:10.1172/ JCI200214861.
    • (2002) J. Clin. Invest. , vol.110 , pp. 239-246
    • Yanagita, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.