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Volumn 17, Issue 2, 2010, Pages

Bone morphogenetic proteins in breast cancer: Dual role in tumourigenesis?

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 15; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 8; BONE MORPHOGENETIC PROTEIN RECEPTOR; GROWTH DIFFERENTIATION FACTOR 9; GROWTH DIFFERENTIATION FACTOR 9A; OSTEOGENIC PROTEIN 1; OSTEOGENIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 77953590859     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1677/ERC-09-0273     Document Type: Review
Times cited : (99)

References (171)
  • 2
    • 34249036783 scopus 로고    scopus 로고
    • A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7
    • Alarmo EL, Kuukasjarvi T, Karhu R & Kallioniemi A 2007 A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7. Breast Cancer Research and Treatment 103 239-246.
    • (2007) Breast Cancer Research and Treatment , vol.103 , pp. 239-246
    • Alarmo, E.L.1    Kuukasjarvi, T.2    Karhu, R.3    Kallioniemi, A.4
  • 5
    • 33746255899 scopus 로고    scopus 로고
    • Gene amplification in cancer
    • Albertson DG 2006 Gene amplification in cancer. Trends in Genetics 22 447-455.
    • (2006) Trends in Genetics , vol.22 , pp. 447-455
    • Albertson, D.G.1
  • 7
    • 0035995602 scopus 로고    scopus 로고
    • The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis
    • Anderson E 2002 The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis. Breast Cancer Research 4 197-201.
    • (2002) Breast Cancer Research , vol.4 , pp. 197-201
    • Anderson, E.1
  • 8
    • 0035012642 scopus 로고    scopus 로고
    • Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction
    • Aoki H, Fujii M, Imamura T, Yagi K, Takehara K, Kato M & Miyazono K 2001 Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction. Journal of Cell Science 114 1483-1489. (Pubitemid 32427835)
    • (2001) Journal of Cell Science , vol.114 , Issue.8 , pp. 1483-1489
    • Aoki, H.1    Fujii, M.2    Imamura, T.3    Yagi, K.4    Takehara, K.5    Kato, M.6    Miyazono, K.7
  • 10
    • 0033372736 scopus 로고    scopus 로고
    • Identification of bone morphogenetic proteins and their receptors in human breast cancer cell lines: Importance of BMP2
    • Arnold SF, Tims E & Mcgrath BE 1999 Identification of bone morphogenetic proteins and their receptors in human breast cancer cell lines: importance of BMP2. Cytokine 11 1031-1037.
    • (1999) Cytokine , vol.11 , pp. 1031-1037
    • Arnold, S.F.1    Tims, E.2    Mcgrath, B.E.3
  • 13
  • 14
    • 0036399170 scopus 로고    scopus 로고
    • Extracellular regulation of BMP signaling in vertebrates: A cocktail of modulators
    • Balemans W & Van Hul W 2002 Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Developmental Biology 250 231-250.
    • (2002) Developmental Biology , vol.250 , pp. 231-250
    • Balemans, W.1    Van Hul, W.2
  • 16
    • 0033534572 scopus 로고    scopus 로고
    • Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-β superfamily
    • Barbara NP, Wrana JL & Letarte M 1999 Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-β superfamily. Journal of Biological Chemistry 274 584-594. (Pubitemid 129535212)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.2 , pp. 584-594
    • Barbara, N.P.1    Wrana, J.L.2    Letarte, M.3
  • 19
    • 0037241807 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their antagonists in skin and hair follicle biology
    • Botchkarev VA 2003 Bone morphogenetic proteins and their antagonists in skin and hair follicle biology. Journal of Investigative Dermatology 120 36-47.
    • (2003) Journal of Investigative Dermatology , vol.120 , pp. 36-47
    • Botchkarev, V.A.1
  • 20
    • 0035504887 scopus 로고    scopus 로고
    • Intracellular BMP signaling regulation in vertebrates: Pathway or network?
    • von Bubnoff A & Cho KW 2001 Intracellular BMP signaling regulation in vertebrates: pathway or network? Developmental Biology 239 1-14.
    • (2001) Developmental Biology , vol.239 , pp. 1-14
    • Von Bubnoff, A.1    Cho, K.W.2
  • 23
    • 0034332551 scopus 로고    scopus 로고
    • Bone morphogenetic proteins secreted by breast cancer cells upregulate bone sialoprotein expression in preosteoblast cells
    • Bunyaratavej P, Hullinger TG & Somerman MJ 2000 Bone morphogenetic proteins secreted by breast cancer cells upregulate bone sialoprotein expression in preosteoblast cells. Experimental Cell Research 260 324-333.
    • (2000) Experimental Cell Research , vol.260 , pp. 324-333
    • Bunyaratavej, P.1    Hullinger, T.G.2    Somerman, M.J.3
  • 24
    • 1642473157 scopus 로고    scopus 로고
    • The transforming growth factor-β superfamily of receptors
    • de Caestecker M 2004 The transforming growth factor-β superfamily of receptors. Cytokine and Growth Factor Reviews 15 1-11.
    • (2004) Cytokine and Growth Factor Reviews , vol.15 , pp. 1-11
    • De Caestecker, M.1
  • 25
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonists, and the skeleton
    • Canalis E, Economides AN & Gazzerro E 2003 Bone morphogenetic proteins, their antagonists, and the skeleton. Endocrine Reviews 24 218-235.
    • (2003) Endocrine Reviews , vol.24 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 26
    • 0036904895 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian transforming growth factor-β superfamily
    • Chang H, Brown CW & Matzuk MM 2002 Genetic analysis of the mammalian transforming growth factor-β superfamily. Endocrine Reviews 23 787-823.
    • (2002) Endocrine Reviews , vol.23 , pp. 787-823
    • Chang, H.1    Brown, C.W.2    Matzuk, M.M.3
  • 27
    • 1642302199 scopus 로고    scopus 로고
    • Elucidation of epigenetic inactivation of SMAD8 in cancer using targeted expressed gene display
    • Cheng KH, Ponte JF & Thiagalingam S 2004 Elucidation of epigenetic inactivation of SMAD8 in cancer using targeted expressed gene display. Cancer Research 64 1639-1646.
    • (2004) Cancer Research , vol.64 , pp. 1639-1646
    • Cheng, K.H.1    Ponte, J.F.2    Thiagalingam, S.3
  • 28
    • 33750964878 scopus 로고    scopus 로고
    • Molecular interactions between Tbx3 and Bmp4 and amodel for dorsoventral positioning of mammary gland development
    • Cho KW, Kim JY, Song SJ, Farrell E, Eblaghie MC, Kim HJ, Tickle C & Jung HS 2006 Molecular interactions between Tbx3 and Bmp4 and amodel for dorsoventral positioning of mammary gland development. PNAS 103 16788-16793.
    • (2006) PNAS , vol.103 , pp. 16788-16793
    • Cho, K.W.1    Kim, J.Y.2    Song, S.J.3    Farrell, E.4    Eblaghie, M.C.5    Kim, H.J.6    Tickle, C.7    Jung, H.S.8
  • 29
    • 0033579799 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein 6 in normal mammary tissue and breast cancer cell lines and its regulation by epidermal growth factor
    • Clement JH, Sanger J & Hoffken K 1999 Expression of bone morphogenetic protein 6 in normal mammary tissue and breast cancer cell lines and its regulation by epidermal growth factor. International Journal of Cancer 80 250-256.
    • (1999) International Journal of Cancer , vol.80 , pp. 250-256
    • Clement, J.H.1    Sanger, J.2    Hoffken, K.3
  • 32
    • 0033545215 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases
    • Constam DB & Robertson EJ 1999 Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. Journal of Cell Biology 144 139-149.
    • (1999) Journal of Cell Biology , vol.144 , pp. 139-149
    • Constam, D.B.1    Robertson, E.J.2
  • 33
    • 33847017335 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells
    • Deng H, Makizumi R, Ravikumar TS, Dong H, Yang W & Yang WL 2007 Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells. Experimental Cell Research 313 1033-1044.
    • (2007) Experimental Cell Research , vol.313 , pp. 1033-1044
    • Deng, H.1    Makizumi, R.2    Ravikumar, T.S.3    Dong, H.4    Yang, W.5    Yang, W.L.6
  • 34
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-β family signalling
    • Derynck R & Zhang YE 2003 Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425 577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 35
    • 0034785348 scopus 로고    scopus 로고
    • TGF-β signaling in tumor suppression and cancer progression
    • Derynck R, Akhurst RJ & Balmain A 2001 TGF-β signaling in tumor suppression and cancer progression. Nature Genetics 29 117-129.
    • (2001) Nature Genetics , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 39
    • 41749097417 scopus 로고    scopus 로고
    • Bone morphogenetic protein 6 inhibit stress-induced breast cancer cells apoptosis via both smad and P38 pathways
    • Du J, Yang S, Wang Z, Zhai C, Yuan W, Lei R, Zhang J & Zhu T 2007 Bone morphogenetic protein 6 inhibit stress-induced breast cancer cells apoptosis via both smad and P38 pathways. Journal of Cellular Biochemistry 103 1584-1597.
    • (2007) Journal of Cellular Biochemistry , vol.103 , pp. 1584-1597
    • Du, J.1    Yang, S.2    Wang, Z.3    Zhai, C.4    Yuan, W.5    Lei, R.6    Zhang, J.7    Zhu, T.8
  • 40
    • 64149085515 scopus 로고    scopus 로고
    • BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1
    • Du J, Yang S, An D, Hu F, Yuan W, Zhai C & Zhu T 2009 BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1. Cell Research 19 487-496.
    • (2009) Cell Research , vol.19 , pp. 487-496
    • Du, J.1    Yang, S.2    An, D.3    Hu, F.4    Yuan, W.5    Zhai, C.6    Zhu, T.7
  • 41
    • 0034128748 scopus 로고    scopus 로고
    • The family of bone morphogenetic proteins
    • Ducy P & Karsenty G 2000 The family of bone morphogenetic proteins. Kidney International 57 2207-2214.
    • (2000) Kidney International , vol.57 , pp. 2207-2214
    • Ducy, P.1    Karsenty, G.2
  • 42
    • 0037102474 scopus 로고    scopus 로고
    • Mechanism for the action of bone morphogenetic proteins and regulation of their activity
    • Ebara S & Nakayama K 2002 Mechanism for the action of bone morphogenetic proteins and regulation of their activity. Spine 27 S10-S15.
    • (2002) Spine , vol.27
    • Ebara, S.1    Nakayama, K.2
  • 45
    • 34248371651 scopus 로고    scopus 로고
    • Potential drug targets within bone morphogenetic protein signaling pathways
    • Gazzerro E & Minetti C 2007 Potential drug targets within bone morphogenetic protein signaling pathways. Current Opinion in Pharmacology 7 325-333.
    • (2007) Current Opinion in Pharmacology , vol.7 , pp. 325-333
    • Gazzerro, E.1    Minetti, C.2
  • 46
    • 0034698099 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 induces cyclin kinase inhibitor p21 and hypophosphorylation of retinoblastoma protein in estradiol-treated MCF-7 human breast cancer cells
    • Ghosh-Choudhury N, Ghosh-Choudhury G, Celeste A, Ghosh PM, Moyer M, Abboud SL & Kreisberg J 2000a Bone morphogenetic protein-2 induces cyclin kinase inhibitor p21 and hypophosphorylation of retinoblastoma protein in estradiol-treated MCF-7 human breast cancer cells. Biochimica et Biophysica Acta 1497 186-196.
    • (2000) Biochimica et Biophysica Acta , vol.1497 , pp. 186-196
    • Ghosh-Choudhury, N.1    Ghosh-Choudhury, G.2    Celeste, A.3    Ghosh, P.M.4    Moyer, M.5    Abboud, S.L.6    Kreisberg, J.7
  • 47
    • 0034674353 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 blocks MDA MB 231 human breast cancer cell proliferation by inhibiting cyclin-dependent kinase-mediated retinoblastoma protein phosphorylation
    • Ghosh-Choudhury N, Woodruff K, QiW, Celeste A, Abboud SL & Ghosh Choudhury G 2000b Bone morphogenetic protein-2 blocks MDA MB 231 human breast cancer cell proliferation by inhibiting cyclin-dependent kinase-mediated retinoblastoma protein phosphorylation. Biochemical and Biophysical Research Communications 272 705-711.
    • (2000) Biochemical and Biophysical Research Communications , vol.272 , pp. 705-711
    • Ghosh-Choudhury, N.1    Woodruff, K.2    Qiw Celeste, A.3    Abboud, S.L.4    Ghosh Choudhury, G.5
  • 48
    • 0037031854 scopus 로고    scopus 로고
    • Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription
    • Ghosh-Choudhury N, Abboud SL, Nishimura R, Celeste A, Mahimainathan L & Choudhury GG 2002 Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription. Journal of Biological Chemistry 277 33361-33368.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 33361-33368
    • Ghosh-Choudhury, N.1    Abboud, S.L.2    Nishimura, R.3    Celeste, A.4    Mahimainathan, L.5    Choudhury, G.G.6
  • 49
    • 0034021776 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
    • Gilboa L, Nohe A, Geissendorfer T, Sebald W, Henis YI & Knaus P 2000 Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Molecular Biology of the Cell 11 1023-1035. (Pubitemid 30159319)
    • (2000) Molecular Biology of the Cell , vol.11 , Issue.3 , pp. 1023-1035
    • Gilboa, L.1    Nohe, A.2    Geissendorfer, T.3    Sebald, W.4    Henis, Y.I.5    Knaus, P.6
  • 51
    • 0030042590 scopus 로고    scopus 로고
    • Three-dimensional structure of recombinant human osteogenic protein 1: Structural paradigm for the transforming growth factor β superfamily
    • Griffith DL, Keck PC, Sampath TK, Rueger DC & Carlson WD 1996 Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor β superfamily. PNAS 93 878-883.
    • (1996) PNAS , vol.93 , pp. 878-883
    • Griffith, D.L.1    Keck, P.C.2    Sampath, T.K.3    Rueger, D.C.4    Carlson, W.D.5
  • 53
    • 1042301228 scopus 로고    scopus 로고
    • Identification of potential modifiers of Runx2/Cbfa1 activity in C2C12 cells in response to bone morphogenetic protein-7
    • Gu K, Zhang L, Jin T & Rutherford RB 2004 Identification of potential modifiers of Runx2/Cbfa1 activity in C2C12 cells in response to bone morphogenetic protein-7. Cells, Tissues, Organs 176 28-40.
    • (2004) Cells, Tissues, Organs , vol.176 , pp. 28-40
    • Gu, K.1    Zhang, L.2    Jin, T.3    Rutherford, R.B.4
  • 54
    • 34250847035 scopus 로고    scopus 로고
    • The role of growth differentiation factor-9 (GDF-9) and its analog, GDF-9b/BMP-15, in human breast cancer
    • Hanavadi S, Martin TA, Watkins G, Mansel RE & Jiang WG 2007 The role of growth differentiation factor-9 (GDF-9) and its analog, GDF-9b/BMP-15, in human breast cancer. Annals of Surgical Oncology 14 2159-2166.
    • (2007) Annals of Surgical Oncology , vol.14 , pp. 2159-2166
    • Hanavadi, S.1    Martin, T.A.2    Watkins, G.3    Mansel, R.E.4    Jiang, W.G.5
  • 55
    • 33749246730 scopus 로고    scopus 로고
    • Mutations of TGFb signaling molecules in human disease
    • Harradine KA & Akhurst RJ 2006 Mutations of TGFb signaling molecules in human disease. Annals of Medicine 38 403-414.
    • (2006) Annals of Medicine , vol.38 , pp. 403-414
    • Harradine, K.A.1    Akhurst, R.J.2
  • 56
    • 0034695506 scopus 로고    scopus 로고
    • OAZ uses distinct DNA- And protein-binding zinc fingers in separate BMP- Smad and Olf signaling pathways
    • Hata A, Seoane J, Lagna G, Montalvo E, Hemmati-Brivanlou A & Massague J 2000 OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100 229-240. (Pubitemid 30064911)
    • (2000) Cell , vol.100 , Issue.2 , pp. 229-240
    • Hata, A.1    Seoane, J.2    Lagna, G.3    Montalvo, E.4    Hemmati-Brivanlou, A.5    Massague, J.6
  • 57
    • 0035800764 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway
    • Hay E, Lemonnier J, Fromigue O & Marie PJ 2001 Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway. Journal of Biological Chemistry 276 29028-29036.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 29028-29036
    • Hay, E.1    Lemonnier, J.2    Fromigue, O.3    Marie, P.J.4
  • 58
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K & ten Dijke P 1997 TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390 465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 59
    • 21344473027 scopus 로고    scopus 로고
    • First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer
    • Helms MW, Packeisen J, August C, Schittek B, Boecker W, Brandt BH & Buerger H 2005 First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer. Journal of Pathology 206 366-376.
    • (2005) Journal of Pathology , vol.206 , pp. 366-376
    • Helms, M.W.1    Packeisen, J.2    August, C.3    Schittek, B.4    Boecker, W.5    Brandt, B.H.6    Buerger, H.7
  • 60
    • 34249775225 scopus 로고    scopus 로고
    • Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes
    • Herpin A & Cunningham C 2007 Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes. FEBS Journal 274 2977-2985.
    • (2007) FEBS Journal , vol.274 , pp. 2977-2985
    • Herpin, A.1    Cunningham, C.2
  • 62
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • Hogan BL 1996a Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes and Development 10 1580-1594. (Pubitemid 26268864)
    • (1996) Genes and Development , vol.10 , Issue.13 , pp. 1580-1594
    • Hogan, B.L.M.1
  • 65
    • 1842425809 scopus 로고    scopus 로고
    • P38MAPK acts in the BMP7-dependent stimulatory pathway during epithelial cell morphogenesis and is regulated by Smad1
    • Hu MC, Wasserman D, Hartwig S & Rosenblum ND 2004 p38MAPK acts in the BMP7-dependent stimulatory pathway during epithelial cell morphogenesis and is regulated by Smad1. Journal of Biological Chemistry 279 12051-12059.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 12051-12059
    • Hu, M.C.1    Wasserman, D.2    Hartwig, S.3    Rosenblum, N.D.4
  • 67
    • 0034533657 scopus 로고    scopus 로고
    • Signaling of transforming growth factor-β family members through Smad proteins
    • Itoh S, Itoh F, Goumans MJ & ten Dijke P 2000 Signaling of transforming growth factor-β family members through Smad proteins. European Journal of Biochemistry 267 6954-6967.
    • (2000) European Journal of Biochemistry , vol.267 , pp. 6954-6967
    • Itoh, S.1    Itoh, F.2    Goumans, M.J.3    Ten Dijke, P.4
  • 69
    • 24644476507 scopus 로고    scopus 로고
    • Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: Implications for carcinogenesis
    • Javelaud D & Mauviel A 2005 Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: implications for carcinogenesis. Oncogene 24 5742-5750.
    • (2005) Oncogene , vol.24 , pp. 5742-5750
    • Javelaud, D.1    Mauviel, A.2
  • 70
    • 33846069310 scopus 로고    scopus 로고
    • BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway
    • Jin EJ, Lee SY, Choi YA, Jung JC, Bang OS & Kang SS 2006 BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway. Molecules and Cells 22 353-359.
    • (2006) Molecules and Cells , vol.22 , pp. 353-359
    • Jin, E.J.1    Lee, S.Y.2    Choi, Y.A.3    Jung, J.C.4    Bang, O.S.5    Kang, S.S.6
  • 74
    • 0032029606 scopus 로고    scopus 로고
    • Signal transduction by bone morphogenetic proteins
    • DOI 10.1016/S1359-6101(97)00036-1, PII S1359610197000361
    • Kawabata M, Imamura T & Miyazono K 1998 Signal transduction by bone morphogenetic proteins. Cytokine and Growth Factor Reviews 9 49-61. (Pubitemid 28280536)
    • (1998) Cytokine and Growth Factor Reviews , vol.9 , Issue.1 , pp. 49-61
    • Kawabata, M.1    Imamura, T.2    Miyazono, K.3
  • 75
    • 33745065756 scopus 로고    scopus 로고
    • Common critical pathways in embryogenesis and cancer
    • Kelleher FC, Fennelly D & RaffertyM2006 Common critical pathways in embryogenesis and cancer. Acta Oncologica 45 375-388.
    • (2006) Acta Oncologica , vol.45 , pp. 375-388
    • Kelleher, F.C.1    Fennelly, D.2    Rafferty, M.3
  • 78
    • 78649334675 scopus 로고    scopus 로고
    • Parallel inhibition of cell growth and induction of cell migration and invasion in breast cancer cells by bone morphogenetic protein 4
    • in press
    • Ketolainen JM, Alarmo EL, Tuominen VJ & Kallioniemi A 2010 Parallel inhibition of cell growth and induction of cell migration and invasion in breast cancer cells by bone morphogenetic protein 4. Breast Cancer Research and Treatment [in press].
    • (2010) Breast Cancer Research and Treatment
    • Ketolainen, J.M.1    Alarmo, E.L.2    Tuominen, V.J.3    Kallioniemi, A.4
  • 79
    • 39049188065 scopus 로고    scopus 로고
    • Role of bone morphogenetic proteins in transitional cell carcinoma cells
    • Kim IY & Kim SJ 2006 Role of bone morphogenetic proteins in transitional cell carcinoma cells. Cancer Letters 241 118-123.
    • (2006) Cancer Letters , vol.241 , pp. 118-123
    • Kim, I.Y.1    Kim, S.J.2
  • 80
    • 0342657717 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues
    • Kim IY, Lee DH, Ahn HJ, Tokunaga H, Song W, Devereaux LM, Jin D, Sampath TK & Morton RA 2000 Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues. Cancer Research 60 2840-2844.
    • (2000) Cancer Research , vol.60 , pp. 2840-2844
    • Kim, I.Y.1    Lee, D.H.2    Ahn, H.J.3    Tokunaga, H.4    Song, W.5    Devereaux, L.M.6    Jin, D.7    Sampath, T.K.8    Morton, R.A.9
  • 81
    • 7044221776 scopus 로고    scopus 로고
    • Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells
    • Kim IY, Lee DH, Lee DK, Ahn HJ, Kim MM, Kim SJ & Morton RA 2004 Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells. Oncogene 23 7651-7659.
    • (2004) Oncogene , vol.23 , pp. 7651-7659
    • Kim, I.Y.1    Lee, D.H.2    Lee, D.K.3    Ahn, H.J.4    Kim, M.M.5    Kim, S.J.6    Morton, R.A.7
  • 82
    • 0034625342 scopus 로고    scopus 로고
    • BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6
    • Kimura N, Matsuo R, Shibuya H, Nakashima K & Taga T 2000 BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6. Journal of Biological Chemistry 275 17647-17652.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 17647-17652
    • Kimura, N.1    Matsuo, R.2    Shibuya, H.3    Nakashima, K.4    Taga, T.5
  • 83
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley DM 1994 The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes and Development 8 133-146. (Pubitemid 2044355)
    • (1994) Genes and Development , vol.8 , Issue.2 , pp. 133-146
    • Kingsley, D.M.1
  • 85
    • 0032908128 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo
    • Kleeff J, Maruyama H, Ishiwata T, Sawhney H, Friess H, Buchler MW & Korc M 1999 Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo. Gastroenterology 116 1202-1216.
    • (1999) Gastroenterology , vol.116 , pp. 1202-1216
    • Kleeff, J.1    Maruyama, H.2    Ishiwata, T.3    Sawhney, H.4    Friess, H.5    Buchler, M.W.6    Korc, M.7
  • 87
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor b and bone morphogenetic protein
    • Kowanetz M, Valcourt U, Bergstrom R, Heldin CH & Moustakas A 2004 Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor b and bone morphogenetic protein. Molecular and Cellular Biology 24 4241-4254.
    • (2004) Molecular and Cellular Biology , vol.24 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergstrom, R.3    Heldin, C.H.4    Moustakas, A.5
  • 88
    • 0030773834 scopus 로고    scopus 로고
    • Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
    • Kretzschmar M, Doody J & Massague J 1997 Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1. Nature 389 618-622.
    • (1997) Nature , vol.389 , pp. 618-622
    • Kretzschmar, M.1    Doody, J.2    Massague, J.3
  • 91
    • 32244447227 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 stimulation of tumor growth involves the activation of Smad-1/5
    • Langenfeld EM, Kong Y & Langenfeld J 2006 Bone morphogenetic protein 2 stimulation of tumor growth involves the activation of Smad-1/5. Oncogene 25 685-692.
    • (2006) Oncogene , vol.25 , pp. 685-692
    • Langenfeld, E.M.1    Kong, Y.2    Langenfeld, J.3
  • 99
    • 0347991862 scopus 로고    scopus 로고
    • Integration of Smad and MAPK pathways: A link and a linker revisited
    • Massague J 2003 Integration of Smad and MAPK pathways: a link and a linker revisited. Genes and Development 17 2993-2997.
    • (2003) Genes and Development , vol.17 , pp. 2993-2997
    • Massague, J.1
  • 100
    • 33646562542 scopus 로고    scopus 로고
    • The logic of TGFβ signaling
    • Massague J & Gomis RR 2006 The logic of TGFβ signaling. FEBS Letters 580 2811-2820.
    • (2006) FEBS Letters , vol.580 , pp. 2811-2820
    • Massague, J.1    Gomis, R.R.2
  • 101
    • 0034644472 scopus 로고    scopus 로고
    • TGFb signaling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW & Lo RS 2000 TGFb signaling in growth control, cancer, and heritable disorders. Cell 103 295-309.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 103
    • 1642402864 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein-7 (BMP-7) in human prostate
    • Masuda H, Fukabori Y, Nakano K, Shimizu N & Yamanaka H 2004 Expression of bone morphogenetic protein-7 (BMP-7) in human prostate. Prostate 59 101-106.
    • (2004) Prostate , vol.59 , pp. 101-106
    • Masuda, H.1    Fukabori, Y.2    Nakano, K.3    Shimizu, N.4    Yamanaka, H.5
  • 104
    • 0034016101 scopus 로고    scopus 로고
    • Positive and negative regulation of TGF-β signaling
    • Miyazono K 2000 Positive and negative regulation of TGF-β signaling. Journal of Cell Science 113 1101-1109. (Pubitemid 30229527)
    • (2000) Journal of Cell Science , vol.113 , Issue.7 , pp. 1101-1109
    • Miyazono, K.1
  • 105
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk
    • Miyazono K, Maeda S & Imamura T 2005 BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine and Growth Factor Reviews 16 251-263.
    • (2005) Cytokine and Growth Factor Reviews , vol.16 , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 106
    • 33845997387 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 abrogates lumen formation by mammary epithelial cells and promotes invasive growth
    • Montesano R 2007 Bone morphogenetic protein-4 abrogates lumen formation by mammary epithelial cells and promotes invasive growth. Biochemical and Biophysical Research Communications 353 817-822.
    • (2007) Biochemical and Biophysical Research Communications , vol.353 , pp. 817-822
    • Montesano, R.1
  • 107
    • 47749155179 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 strongly potentiates growth factor-induced proliferation of mammary epithelial cells
    • Montesano R, Sarkozi R & Schramek H 2008 Bone morphogenetic protein-4 strongly potentiates growth factor-induced proliferation of mammary epithelial cells. Biochemical and Biophysical Research Communications 374 164-168.
    • (2008) Biochemical and Biophysical Research Communications , vol.374 , pp. 164-168
    • Montesano, R.1    Sarkozi, R.2    Schramek, H.3
  • 108
    • 0038107486 scopus 로고    scopus 로고
    • Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads
    • Murakami G, Watabe T, Takaoka K, Miyazono K & Imamura T 2003 Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads. Molecular Biology of the Cell 14 2809-2817.
    • (2003) Molecular Biology of the Cell , vol.14 , pp. 2809-2817
    • Murakami, G.1    Watabe, T.2    Takaoka, K.3    Miyazono, K.4    Imamura, T.5
  • 109
    • 0032979875 scopus 로고    scopus 로고
    • Molecular evolution of a developmental pathway: Phylogenetic analyses of transforming growth factor-β family ligands, receptors and Smad signal transducers
    • Newfeld SJ, Wisotzkey RG & Kumar S 1999 Molecular evolution of a developmental pathway: phylogenetic analyses of transforming growth factor-β family ligands, receptors and Smad signal transducers. Genetics 152 783-795. (Pubitemid 29272728)
    • (1999) Genetics , vol.152 , Issue.2 , pp. 783-795
    • Newfeld, S.J.1    Wisotzkey, R.G.2    Kumar, S.3
  • 110
  • 111
  • 118
    • 0034997337 scopus 로고    scopus 로고
    • BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways
    • Piscione TD, Phan T & Rosenblum ND 2001 BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways. American Journal of Physiology. Renal Physiology 280 F19-F33. (Pubitemid 32473293)
    • (2001) American Journal of Physiology - Renal Physiology , vol.280 , Issue.1
    • Piscione, T.D.1    Phan, T.2    Rosenblum, N.D.3
  • 119
    • 0036148661 scopus 로고    scopus 로고
    • Role of Smad1 and Smad4 proteins in the induction of p21WAF1, Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells
    • Pouliot F & Labrie C 2002 Role of Smad1 and Smad4 proteins in the induction of p21WAF1, Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells. Journal of Endocrinology 172 187-198.
    • (2002) Journal of Endocrinology , vol.172 , pp. 187-198
    • Pouliot, F.1    Labrie, C.2
  • 120
    • 0037439923 scopus 로고    scopus 로고
    • Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells
    • Pouliot F, Blais A & Labrie C 2003 Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells. Cancer Research 63 277-281. (Pubitemid 36152479)
    • (2003) Cancer Research , vol.63 , Issue.2 , pp. 277-281
    • Pouliot, F.1    Blais, A.2    Labrie, C.3
  • 123
    • 0031105160 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: An unconventional approach to isolation of first mammalian morphogens
    • Reddi AH 1997 Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens. Cytokine and Growth Factor Reviews 8 11-20.
    • (1997) Cytokine and Growth Factor Reviews , vol.8 , pp. 11-20
    • Reddi, A.H.1
  • 124
    • 0031909665 scopus 로고    scopus 로고
    • Role of morphogenetic proteins in skeletal tissue engineering and regeneration
    • Reddi AH 1998 Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nature Biotechnology 16 247-252.
    • (1998) Nature Biotechnology , vol.16 , pp. 247-252
    • Reddi, A.H.1
  • 125
    • 0035100974 scopus 로고    scopus 로고
    • Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: Noggin, chordin and DAN
    • Reddi AH 2001 Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: noggin, chordin and DAN. Arthritis Research 3 1-5.
    • (2001) Arthritis Research , vol.3 , pp. 1-5
    • Reddi, A.H.1
  • 126
    • 0035990985 scopus 로고    scopus 로고
    • Differential gene expression of TGF-β family members and osteopontin in breast tumor tissue: Analysis by real-time quantitative PCR
    • Reinholz MM, Iturria SJ, Ingle JN & Roche PC 2002 Differential gene expression of TGF-β family members and osteopontin in breast tumor tissue: analysis by real-time quantitative PCR. Breast Cancer Research and Treatment 74 255-269.
    • (2002) Breast Cancer Research and Treatment , vol.74 , pp. 255-269
    • Reinholz, M.M.1    Iturria, S.J.2    Ingle, J.N.3    Roche, P.C.4
  • 130
    • 14944345010 scopus 로고    scopus 로고
    • Tenascin-W is found in malignant mammary tumors, promotes a8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-α induced expression in vitro
    • Scherberich A, Tucker RP, Degen M, Brown-Luedi M, Andres AC & Chiquet-Ehrismann R 2005 Tenascin-W is found in malignant mammary tumors, promotes a8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-α induced expression in vitro. Oncogene 24 1525-1532.
    • (2005) Oncogene , vol.24 , pp. 1525-1532
    • Scherberich, A.1    Tucker, R.P.2    Degen, M.3    Brown-Luedi, M.4    Andres, A.C.5    Chiquet-Ehrismann, R.6
  • 132
    • 36448936383 scopus 로고    scopus 로고
    • TGFβ-SMAD signal transduction: Molecular specificity and functional flexibility. Nature Reviews
    • Schmierer B & Hill CS 2007 TGFβ-SMAD signal transduction: molecular specificity and functional flexibility. Nature Reviews. Molecular Cell Biology 8 970-982.
    • (2007) Molecular Cell Biology , vol.8 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 135
    • 4544286802 scopus 로고    scopus 로고
    • Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction
    • Sebald W, Nickel J, Zhang JL & Mueller TD 2004 Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction. Biological Chemistry 385 697-710.
    • (2004) Biological Chemistry , vol.385 , pp. 697-710
    • Sebald, W.1    Nickel, J.2    Zhang, J.L.3    Mueller, T.D.4
  • 136
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling from cell membrane to the nucleus
    • Shi Y & Massague J 2003 Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 139
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
    • Siegel PM & Massague J 2003 Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer. Nature Reviews. Cancer 3 807-821. (Pubitemid 37376979)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.11 , pp. 807-820
    • Siegel, P.M.1    Massague, J.2
  • 140
  • 141
    • 33845944389 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain
    • Sopory S, Nelsen SM, Degnin C, Wong C & Christian JL 2006 Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain. Journal of Biological Chemistry 281 34021-34031.
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 34021-34031
    • Sopory, S.1    Nelsen, S.M.2    Degnin, C.3    Wong, C.4    Christian, J.L.5
  • 143
    • 57449112721 scopus 로고    scopus 로고
    • Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation
    • Takahashi M, Otsuka F, Miyoshi T, Otani H, Goto J, Yamashita M, Ogura T, Makino H & Doihara H 2008 Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation. Journal of Endocrinology 199 445-455.
    • (2008) Journal of Endocrinology , vol.199 , pp. 445-455
    • Takahashi, M.1    Otsuka, F.2    Miyoshi, T.3    Otani, H.4    Goto, J.5    Yamashita, M.6    Ogura, T.7    Makino, H.8    Doihara, H.9
  • 146
    • 16344378397 scopus 로고    scopus 로고
    • TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
    • Valcourt U, Kowanetz M, Niimi H, Heldin CH & Moustakas A 2005 TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Molecular Biology of the Cell 16 1987-2002.
    • (2005) Molecular Biology of the Cell , vol.16 , pp. 1987-2002
    • Valcourt, U.1    Kowanetz, M.2    Niimi, H.3    Heldin, C.H.4    Moustakas, A.5
  • 147
    • 33750689159 scopus 로고    scopus 로고
    • Targeting factors involved in bone remodeling as treatment strategies in prostate cancer bone metastasis
    • Vessella RL & Corey E 2006 Targeting factors involved in bone remodeling as treatment strategies in prostate cancer bone metastasis. Clinical Cancer Research 12 6285s-6290s.
    • (2006) Clinical Cancer Research , vol.12
    • Vessella, R.L.1    Corey, E.2
  • 148
    • 0141594935 scopus 로고    scopus 로고
    • From developmental disorder to heritable cancer: It's all in the BMP/TGF-β family. Nature Reviews
    • Waite KA & Eng C 2003a From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family. Nature Reviews. Genetics 4 763-773.
    • (2003) Genetics , vol.4 , pp. 763-773
    • Waite, K.A.1    Eng, C.2
  • 149
    • 0037444213 scopus 로고    scopus 로고
    • BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels
    • Waite KA & Eng C 2003b BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels. Human Molecular Genetics 12 679-684.
    • (2003) Human Molecular Genetics , vol.12 , pp. 679-684
    • Waite, K.A.1    Eng, C.2
  • 151
    • 34848892451 scopus 로고    scopus 로고
    • The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells
    • Wang N, Lin KK, Lu Z, Lam KS, Newton R, Xu X, Yu Z, Gill GN & Andersen B 2007 The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells. Oncogene 26 6431-6441.
    • (2007) Oncogene , vol.26 , pp. 6431-6441
    • Wang, N.1    Lin, K.K.2    Lu, Z.3    Lam, K.S.4    Newton, R.5    Xu, X.6    Yu, Z.7    Gill, G.N.8    Andersen, B.9
  • 152
    • 34548410387 scopus 로고    scopus 로고
    • Vitamin D and prevention of breast cancer
    • Welsh J 2007 Vitamin D and prevention of breast cancer. Acta Pharmacologica Sinica 28 1373-1382.
    • (2007) Acta Pharmacologica Sinica , vol.28 , pp. 1373-1382
    • Welsh, J.1
  • 153
    • 0141668933 scopus 로고    scopus 로고
    • CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface
    • Wilkinson L, Kolle G, Wen D, Piper M, Scott J & Little M 2003 CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface. Journal of Biological Chemistry 278 34181-34188.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 34181-34188
    • Wilkinson, L.1    Kolle, G.2    Wen, D.3    Piper, M.4    Scott, J.5    Little, M.6
  • 154
    • 0037102589 scopus 로고    scopus 로고
    • Overview of bone morphogenetic proteins
    • Wozney JM 2002 Overview of bone morphogenetic proteins. Spine 27 S2-S8.
    • (2002) Spine , vol.27
    • Wozney, J.M.1
  • 155
    • 0031974284 scopus 로고    scopus 로고
    • Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair
    • Wozney JM & Rosen V 1998 Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clinical Orthopaedics and Related Research 346 26-37.
    • (1998) Clinical Orthopaedics and Related Research , vol.346 , pp. 26-37
    • Wozney, J.M.1    Rosen, V.2
  • 158
    • 0036283061 scopus 로고    scopus 로고
    • Cross-talk between bone morphogenic proteins and estrogen receptor signaling
    • Yamamoto T, Saatcioglu F & Matsuda T 2002 Cross-talk between bone morphogenic proteins and estrogen receptor signaling. Endocrinology 143 2635-2642.
    • (2002) Endocrinology , vol.143 , pp. 2635-2642
    • Yamamoto, T.1    Saatcioglu, F.2    Matsuda, T.3
  • 159
    • 35148861674 scopus 로고    scopus 로고
    • Targeted repression of bone morphogenetic protein 7, a novel target of the p53 family, triggers proliferative defect in p53-deficient breast cancer cells
    • Yan W & Chen X 2007 Targeted repression of bone morphogenetic protein 7, a novel target of the p53 family, triggers proliferative defect in p53-deficient breast cancer cells. Cancer Research 67 9117-9124.
    • (2007) Cancer Research , vol.67 , pp. 9117-9124
    • Yan, W.1    Chen, X.2
  • 160
    • 21344467705 scopus 로고    scopus 로고
    • Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
    • Yang S, Zhong C, Frenkel B, Reddi AH & Roy-Burman P 2005 Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Research 65 5769-5777.
    • (2005) Cancer Research , vol.65 , pp. 5769-5777
    • Yang, S.1    Zhong, C.2    Frenkel, B.3    Reddi, A.H.4    Roy-Burman, P.5
  • 164
    • 34547580553 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their receptor signaling in prostate cancer
    • Ye L, Lewis-Russell JM, Kyanaston HG & Jiang WG 2007 Bone morphogenetic proteins and their receptor signaling in prostate cancer. Histology and Histopathology 22 1129-1147. (Pubitemid 47470307)
    • (2007) Histology and Histopathology , vol.22 , Issue.10-12 , pp. 1129-1147
    • Ye, L.1    Lewis-Russell, J.M.2    Kyanaston, H.G.3    Jiang, W.G.4
  • 166
  • 167
    • 27144499210 scopus 로고    scopus 로고
    • Activation of bone morphogenetic protein-6 gene transcription in MCF-7 cells by estrogen
    • Zhang M, Yan JD, Zhang L, Wang Q, Lu SJ, Zhang J & Zhu TH 2005 Activation of bone morphogenetic protein-6 gene transcription in MCF-7 cells by estrogen. Chinese Medical Journal 118 1629-1636. (Pubitemid 41489039)
    • (2005) Chinese Medical Journal , vol.118 , Issue.19 , pp. 1629-1636
    • Zhang, M.1    Yan, J.-D.2    Zhang, L.3    Wang, Q.4    Lu, S.-J.5    Zhang, J.6    Zhu, T.-H.7
  • 169
    • 0037250476 scopus 로고    scopus 로고
    • Consequences of knocking out BMP signaling in the mouse
    • Zhao GQ 2003 Consequences of knocking out BMP signaling in the mouse. Genesis 35 43-56.
    • (2003) Genesis , vol.35 , pp. 43-56
    • Zhao, G.Q.1
  • 170
  • 171
    • 0037862003 scopus 로고    scopus 로고
    • New intracellular components of bone morphogenetic protein/Smad signaling cascades
    • Zwijsen A, Verschueren K & Huylebroeck D 2003 New intracellular components of bone morphogenetic protein/Smad signaling cascades. FEBS Letters 546 133-139.
    • (2003) FEBS Letters , vol.546 , pp. 133-139
    • Zwijsen, A.1    Verschueren, K.2    Huylebroeck, D.3


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