The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization

Journal of Clinical Investigation

Volumn 119, Issue 11, 2009, Pages 3462-3471

  Shen, Qi ^a,b   Little, Shawn C ^b   Xu, Meiqi ^a,b   Haupt, Julia ^c,d   Ast, Cindy ^d   Katagiri, Takenobu ^e   Mundlos, Stefan ^c,d   Seemann, Petra ^c,d   Kaplan, Frederick S ^a,b   Mullins, Mary C ^b   Shore, Eileen M ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^e SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; MUTANT PROTEIN; PROCOLLAGEN C PROTEINASE; SERINE;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL CULTURE; CELL LINE; CHICK; CHONDROGENESIS; CONTROLLED STUDY; EMBRYO; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; MAMMAL CELL; NONHUMAN; OSSIFYING MYOSITIS; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; ZEBRA FISH;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; CHICK EMBRYO; CHONDROGENESIS; COS CELLS; MUTATION; MYOSITIS OSSIFICANS; PROTEIN BINDING; SIGNAL TRANSDUCTION; SMAD PROTEINS, RECEPTOR-REGULATED; ZEBRAFISH;

EID: 70449366408     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI37412     Document Type: Article

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