메뉴 건너뛰기




Volumn 22, Issue 10, 2016, Pages 1334-1349

Stroke and neuroinflamation: Role of sexual hormones

Author keywords

Estradiol; Glia; Neuroinflammation; Neuroprotection; OGD; Progesterone; Stroke

Indexed keywords

CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; ESTRADIOL; PROGESTERONE; SEX HORMONE; ANTIINFLAMMATORY AGENT; NEUROPROTECTIVE AGENT;

EID: 84961696470     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161282210160304112834     Document Type: Article
Times cited : (29)

References (301)
  • 4
    • 84912050435 scopus 로고    scopus 로고
    • Alterations in immune cells and mediators in the brain: It's not always neuroinflammation!
    • Estes ML, MCAllister AK. Alterations in immune cells and mediators in the brain: It's not always neuroinflammation!. Brain Pathol 2014; 24: 623-30
    • (2014) Brain Pathol , vol.24 , pp. 623-630
    • Estes, M.L.1    McAllister, A.K.2
  • 5
    • 19544376505 scopus 로고    scopus 로고
    • Inflammation in areas of remote changes following focal brain lesion
    • Block F, Dihné M. Inflammation in areas of remote changes following focal brain lesion. Prog Neurobiol 2005; 75: 342-65
    • (2005) Prog Neurobiol , vol.75 , pp. 342-365
    • Block, F.1    Dihné, M.2
  • 6
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas S-M, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. Br J Pharmacol 2006; 147: S232-40
    • (2006) Br J Pharmacol , vol.147 , pp. SS40-S232
    • Lucas, S.-M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 7
    • 0029692418 scopus 로고    scopus 로고
    • Significance of the inflammatory response in brain ischemia
    • Baethmann A, Kempski O, Plesnila N, Staub F, Vienna: Springer
    • Hallenbeck J. Significance of the inflammatory response in brain ischemia. In: Baethmann A, Kempski O, Plesnila N, Staub F, Eds. Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma. Vienna: Springer 1996; pp. 27-31
    • (1996) Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma , pp. 27-31
    • Hallenbeck, J.1
  • 9
    • 84872091789 scopus 로고    scopus 로고
    • Heart disease and stroke statistics 2013. Update a report from the american heart association
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics 2013. Update a report from the american heart association. Circulation 2013; 127: e6-245
    • (2013) Circulation , vol.127 , pp. 6-245
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 10
    • 84899971257 scopus 로고    scopus 로고
    • Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice
    • Lenglet S, Montecucco F, Denes A, et al. Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. J Cereb Blood Flow Metab 2014; 34: 802-12
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 802-812
    • Lenglet, S.1    Montecucco, F.2    Denes, A.3
  • 11
    • 77952112006 scopus 로고    scopus 로고
    • Time to treatment with intravenous alteplase and outcome in stroke: An updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials
    • Lees KR, Bluhmki E, von Kummer R, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010; 375: 1695-703
    • (2010) Lancet , vol.375 , pp. 1695-1703
    • Lees, K.R.1    Bluhmki, E.2    Von Kummer, R.3
  • 13
    • 84857477089 scopus 로고    scopus 로고
    • The use of animal models for stroke research: A review
    • Casals JB, Pieri NCG, Feitosa MLT, et al. The use of animal models for stroke research: A review. Comp Med 2011; 61: 305-13
    • (2011) Comp Med , vol.61 , pp. 305-313
    • Casals, J.B.1    Pieri, N.2    Feitosa, M.3
  • 14
    • 34249852075 scopus 로고    scopus 로고
    • Acute ischemic stroke: Overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
    • Durukan A, Tatlisumak T. Acute ischemic stroke: Overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. Pharmacol Biochem Behav 2007; 87: 179-97
    • (2007) Pharmacol Biochem Behav , vol.87 , pp. 179-197
    • Durukan, A.1    Tatlisumak, T.2
  • 15
    • 0041659304 scopus 로고    scopus 로고
    • Animal models of stroke: Do they have value for discovering neuroprotective agents?
    • Green RA, Odergren T, Ashwood T. Animal models of stroke: do they have value for discovering neuroprotective agents? Trends Pharmacol Sci 2003; 24: 402-408
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 402-408
    • Green, R.A.1    Odergren, T.2    Ashwood, T.3
  • 16
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999; 22: 391-7
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 17
    • 84908615923 scopus 로고    scopus 로고
    • Inflammatory response and neuronal necrosis in rats with cerebral ischemia
    • Wu L, Zhang K, Hu G, Yan H, Xie C, Wu X. Inflammatory response and neuronal necrosis in rats with cerebral ischemia. Neural Regeneration Res 2014; 9: 1753-62
    • (2014) Neural Regeneration Res , vol.9 , pp. 1753-1762
    • Wu, L.1    Zhang, K.2    Hu, G.3    Yan, H.4    Xie, C.5    Wu, X.6
  • 18
    • 77953620336 scopus 로고    scopus 로고
    • Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation
    • Denes A, Thornton P, Rothwell NJ, Allan SM. Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation. Brain Behav Immun 2010; 24: 708-23
    • (2010) Brain Behav Immun , vol.24 , pp. 708-723
    • Denes, A.1    Thornton, P.2    Rothwell, N.J.3    Allan, S.M.4
  • 19
    • 33747781747 scopus 로고    scopus 로고
    • Inflammation in stroke and focal cerebral ischemia
    • Huang J, Upadhyay UM, Tamargo RJ. Inflammation in stroke and focal cerebral ischemia. Surg Neurol 2006; 66: 232-45
    • (2006) Surg Neurol , vol.66 , pp. 232-245
    • Huang, J.1    Upadhyay, U.M.2    Tamargo, R.J.3
  • 20
    • 84865052738 scopus 로고    scopus 로고
    • Cerebralcare Granule® attenuates blood-brain barrier disruption after middle cerebral artery occlusion in rats
    • Huang P, Zhou C-M, Qin H, et al. Cerebralcare Granule® attenuates blood-brain barrier disruption after middle cerebral artery occlusion in rats. Exp Neurol 2012; 237: 453-63
    • (2012) Exp Neurol , vol.237 , pp. 453-463
    • Huang, P.1    Zhou, C.-M.2    Qin, H.3
  • 21
    • 36649022397 scopus 로고    scopus 로고
    • Inflammation in ischemic brain injury: Timing is important
    • Kriz J. Inflammation in ischemic brain injury: timing is important. Crit Rev Neurobiol 2006; 18: 145-57
    • (2006) Crit Rev Neurobiol , vol.18 , pp. 145-157
    • Kriz, J.1
  • 22
    • 84896714739 scopus 로고    scopus 로고
    • Glial scar formation occurs in the human brain after ischemic stroke
    • Huang L WZ, ZhuGe Q, Zheng W, et al. Glial scar formation occurs in the human brain after ischemic stroke. Int J Med Sci 2014; 11(4): 344-8
    • (2014) Int J Med Sci , vol.11 , Issue.4 , pp. 344-348
    • Huang, L.1    Zhuge, Q.2    Zheng, W.3
  • 23
    • 0026708978 scopus 로고
    • Brain macrophages: Evaluation of microglia and their functions
    • Thomas WE. Brain macrophages: evaluation of microglia and their functions. Brain Res Rev 1992; 17: 61-74
    • (1992) Brain Res Rev , vol.17 , pp. 61-74
    • Thomas, W.E.1
  • 25
    • 84924976223 scopus 로고    scopus 로고
    • Microglial dynamics and role in the healthy and diseased brain: A paradigm of functional plasticity
    • Gomez-Nicola D, Perry VH. Microglial dynamics and role in the healthy and diseased brain: a paradigm of functional plasticity. Neuroscientist 2015; 21(2): 169-84
    • (2015) Neuroscientist , vol.21 , Issue.2 , pp. 169-184
    • Gomez-Nicola, D.1    Perry, V.H.2
  • 26
    • 77649184973 scopus 로고    scopus 로고
    • Microglia: Biology and pathology
    • Graeber M, Streit W. Microglia: biology and pathology. Acta Neuropathol 2010; 119: 89-105
    • (2010) Acta Neuropathol , vol.119 , pp. 89-105
    • Graeber, M.1    Streit, W.2
  • 27
    • 84874776157 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: Differential regulation by inflammatory mediators
    • Suh H-S, Zhao M-L, Derico L, Choi N, Lee S. Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators. J Neuroinflamm 2013; 10: 37-49
    • (2013) J Neuroinflamm , vol.10 , pp. 37-49
    • Suh, H.-S.1    Zhao, M.-L.2    Derico, L.3    Choi, N.4    Lee, S.5
  • 28
    • 84894574217 scopus 로고    scopus 로고
    • Microglia promote learningdependent synapse formation through BDNF
    • Parkhurst CN, Yang G, Ninan I, et al. Microglia promote learningdependent synapse formation through BDNF. Cell 2013; 155: 1596-609
    • (2013) Cell , vol.155 , pp. 1596-1609
    • Parkhurst, C.N.1    Yang, G.2    Ninan, I.3
  • 29
    • 0027386940 scopus 로고
    • Characterization of microglial reaction after middle cerebral artery occlusion in rat brain
    • Morioka T, Kalehua AN, Streit WJ. Characterization of microglial reaction after middle cerebral artery occlusion in rat brain. J Comp Neurol 1993; 327: 123-32
    • (1993) J Comp Neurol , vol.327 , pp. 123-132
    • Morioka, T.1    Kalehua, A.N.2    Streit, W.J.3
  • 30
    • 84864809822 scopus 로고    scopus 로고
    • Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia
    • Perez-Alvarez M, Maza Md, Anton M, Ordonez L, Wandosell F. Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia. J Neuroinflamm 2012; 9: 157-70
    • (2012) J Neuroinflamm , vol.9 , pp. 157-170
    • Perez-Alvarez, M.1    Md, M.2    Anton, M.3    Ordonez, L.4    Wandosell, F.5
  • 32
    • 0037477629 scopus 로고    scopus 로고
    • Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
    • Lehnardt S, Massillon L, Follett P, et al. Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proc Natl Acad Sci USA 2003; 100: 8514-9
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8514-8519
    • Lehnardt, S.1    Massillon, L.2    Follett, P.3
  • 33
    • 0034726019 scopus 로고    scopus 로고
    • Protective effect of microglial conditioning medium on neuronal damage induced by glutamate
    • Watanabe H, Abe H, Takeuchi S, Tanaka R. Protective effect of microglial conditioning medium on neuronal damage induced by glutamate. Neurosci Lett 2000; 289: 53-6
    • (2000) Neurosci Lett , vol.289 , pp. 53-56
    • Watanabe, H.1    Abe, H.2    Takeuchi, S.3    Tanaka, R.4
  • 34
    • 84897976299 scopus 로고    scopus 로고
    • Microglial priming in neurodegenerative disease
    • Perry VH, Holmes C. Microglial priming in neurodegenerative disease. Nat Rev Neurol 2014; 10: 217-24
    • (2014) Nat Rev Neurol , vol.10 , pp. 217-224
    • Perry, V.H.1    Holmes, C.2
  • 35
    • 70350558453 scopus 로고    scopus 로고
    • Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
    • Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, Popovich PG. Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord. J Neurosci 2009; 29(43): 13435-44
    • (2009) J Neurosci , vol.29 , Issue.43 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3    Alexander, J.K.4    Donnelly, D.J.5    Popovich, P.G.6
  • 36
    • 84963955604 scopus 로고    scopus 로고
    • FAM19A3, a novel secreted protein, modulates the microglia/macrophage polarization dynamics and ameliorates cerebral ischemia
    • Shao Y, Deng T, Zhang T, Li P, Wang Y. FAM19A3, a novel secreted protein, modulates the microglia/macrophage polarization dynamics and ameliorates cerebral ischemia. FEBS Lett 2015; 589: 467-75
    • (2015) FEBS Lett , vol.589 , pp. 467-475
    • Shao, Y.1    Deng, T.2    Zhang, T.3    Li, P.4    Wang, Y.5
  • 37
    • 84858072878 scopus 로고    scopus 로고
    • Comparison of polarization properties of human adult microglia and blood-derived macrophages
    • Durafourt BA, Moore CS, Zammit DA, et al. Comparison of polarization properties of human adult microglia and blood-derived macrophages. Glia 2012; 60: 717-27
    • (2012) Glia , vol.60 , pp. 717-727
    • Durafourt, B.A.1    Moore, C.S.2    Zammit, D.A.3
  • 38
    • 84868209611 scopus 로고    scopus 로고
    • Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
    • Hu X, Li P, Guo Y, et al. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 2012; 43: 3063-70
    • (2012) Stroke , vol.43 , pp. 3063-3070
    • Hu, X.1    Li, P.2    Guo, Y.3
  • 39
    • 84889084386 scopus 로고    scopus 로고
    • Microglia/macrophage polarization dynamics in white matter after traumatic brain injury
    • Wang G, Zhang J, Hu X, et al. Microglia/macrophage polarization dynamics in white matter after traumatic brain injury. J Cereb Blood Flow Metab 2013; 33: 1864-74
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 1864-1874
    • Wang, G.1    Zhang, J.2    Hu, X.3
  • 40
    • 20344398223 scopus 로고    scopus 로고
    • Astrocyte activation and reactive gliosis
    • Pekny M, Nilsson M. Astrocyte activation and reactive gliosis. Glia 2005; 50: 427-34
    • (2005) Glia , vol.50 , pp. 427-434
    • Pekny, M.1    Nilsson, M.2
  • 43
    • 0029058922 scopus 로고
    • A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury
    • Winter CG, Saotome Y, Levison SW, Hirsh D. A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury. Proc Natl Acad Sci USA 1995; 92: 5865-9
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5865-5869
    • Winter, C.G.1    Saotome, Y.2    Levison, S.W.3    Hirsh, D.4
  • 44
    • 0035153212 scopus 로고    scopus 로고
    • Immune function of astrocytes
    • Dong Y, Benveniste EN. Immune function of astrocytes. Glia 2001; 36: 180-90
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 45
    • 0029794601 scopus 로고    scopus 로고
    • Potentiation of oxygen-glucose deprivation-induced neuronal death after induction of iNOS
    • Hewett SJ, Muir JK, Lobner D, Symons A, Choi DW. Potentiation of oxygen-glucose deprivation-induced neuronal death after induction of iNOS. Stroke 1996; 27: 1586-91
    • (1996) Stroke , vol.27 , pp. 1586-1591
    • Hewett, S.J.1    Muir, J.K.2    Lobner, D.3    Symons, A.4    Choi, D.W.5
  • 46
    • 0033152442 scopus 로고    scopus 로고
    • Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice
    • Bush TG, Puvanachandra N, Horner CH, et al. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 1999; 23: 297-308
    • (1999) Neuron , vol.23 , pp. 297-308
    • Bush, T.G.1    Puvanachandra, N.2    Horner, C.H.3
  • 47
    • 0033578230 scopus 로고    scopus 로고
    • Genetically-targeted and conditionally-regulated ablation of astroglial cells in the central, enteric and peripheral nervous systems in adult transgenic mice1
    • Sofroniew MV, Bush TG, Blumauer N, Lawrence K, Mucke L, Johnson HM. Genetically-targeted and conditionally-regulated ablation of astroglial cells in the central, enteric and peripheral nervous systems in adult transgenic mice1. Brain Res 1999; 835: 91-5
    • (1999) Brain Res , vol.835 , pp. 91-95
    • Sofroniew, M.V.1    Bush, T.G.2    Blumauer, N.3    Lawrence, K.4    Mucke, L.5    Johnson, H.M.6
  • 48
    • 84921448756 scopus 로고    scopus 로고
    • Deletion of Atf6 impairs astroglial activation and enhances neuronal death following brain ischemia in mice
    • Yoshikawa A, Kamide T, Hashida K, et al. Deletion of Atf6 impairs astroglial activation and enhances neuronal death following brain ischemia in mice. J Neurochem 2015; 132: 342-53
    • (2015) J Neurochem , vol.132 , pp. 342-353
    • Yoshikawa, A.1    Kamide, T.2    Hashida, K.3
  • 49
    • 39749132193 scopus 로고    scopus 로고
    • Protective role of reactive astrocytes in brain ischemia
    • Li L, Lundkvist A, Andersson D, et al. Protective role of reactive astrocytes in brain ischemia. J Cereb Blood Flow Metab 2007; 28: 468-81
    • (2007) J Cereb Blood Flow Metab , vol.28 , pp. 468-481
    • Li, L.1    Lundkvist, A.2    Ersson, D.3
  • 50
    • 84879794365 scopus 로고    scopus 로고
    • Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion
    • de Pablo Y, Nilsson M, Pekna M, Pekny M. Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion. Histochem Cell Biol 2013; 140: 81-91
    • (2013) Histochem Cell Biol , vol.140 , pp. 81-91
    • De Pablo, Y.1    Nilsson, M.2    Pekna, M.3    Pekny, M.4
  • 51
    • 0027213868 scopus 로고
    • Histologic Assessment of the Age of Recent Brain Infarcts in Man
    • Chuaqui R, Tapia J. Histologic Assessment of the Age of Recent Brain Infarcts in Man. J Neuropathol Exp Neurol 1993; 52: 481-9
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 481-489
    • Chuaqui, R.1    Tapia, J.2
  • 52
    • 8844270954 scopus 로고    scopus 로고
    • Human cerebral infarct: A proposed histopathologic classification based on 137 cases
    • Mena H, Cadavid D, Rushing E. Human cerebral infarct: a proposed histopathologic classification based on 137 cases. Acta Neuropathol 2004; 108: 524-30
    • (2004) Acta Neuropathol , vol.108 , pp. 524-530
    • Mena, H.1    Cadavid, D.2    Rushing, E.3
  • 53
    • 0037532616 scopus 로고    scopus 로고
    • An early and sustained peripheral inflammatory response in acute ischaemic stroke: Relationships with infection and atherosclerosis
    • Emsley HCA, Smith CJ, Gavin CM, et al. An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis. J Neuroimmunol 2003; 139: 93-101
    • (2003) J Neuroimmunol , vol.139 , pp. 93-101
    • Emsley, H.1    Smith, C.J.2    Gavin, C.M.3
  • 54
    • 39349097270 scopus 로고    scopus 로고
    • Early neutrophilia is associated with volume of ischemic tissue in acute stroke
    • Buck BH, Liebeskind DS, Saver JL, et al. Early neutrophilia is associated with volume of ischemic tissue in acute stroke. Stroke 2008; 39: 355-60
    • (2008) Stroke , vol.39 , pp. 355-360
    • Buck, B.H.1    Liebeskind, D.S.2    Saver, J.L.3
  • 55
  • 56
    • 0030497535 scopus 로고    scopus 로고
    • Neuroprotective effect of recombinant neutrophil inhibitory factor in transient focal cerebral ischaemia in the rat
    • Mackay KB, Bailey SJ, King PD, Patel S, Hamilton TC, Campbell CA. Neuroprotective effect of recombinant neutrophil inhibitory factor in transient focal cerebral ischaemia in the rat. Neurodegeneration 1996; 5(4): 319-23
    • (1996) Neurodegeneration , vol.5 , Issue.4 , pp. 319-323
    • Mackay, K.B.1    Bailey, S.J.2    King, P.D.3    Patel, S.4    Hamilton, T.C.5    Campbell, C.A.6
  • 58
    • 0033163359 scopus 로고    scopus 로고
    • Soluble intercellular adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1 and von Willebrand factor in stroke
    • Blann A, Kumar P, Krupinski J, McCollum C, Beevers DG, Lip GYH. Soluble intercellular adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1 and von Willebrand factor in stroke. Blood Coagul Fibrinol 1999; 10: 277-84
    • (1999) Blood Coagul Fibrinol , vol.10 , pp. 277-284
    • Blann, A.1    Kumar, P.2    Krupinski, J.3    McCollum, C.4    Beevers, D.G.5    Lip, G.Y.H.6
  • 59
    • 0029808409 scopus 로고    scopus 로고
    • Carpe´n O, Paetau A, Karjalainen-Lindsberg M-L, Kaste M. Endothelial ICAM-1 Expression Associated With Inflammatory Cell Response in Human Ischemic Stroke
    • Lindsberg PJ, Carpe´n O, Paetau A, Karjalainen-Lindsberg M-L, Kaste M. Endothelial ICAM-1 Expression Associated With Inflammatory Cell Response in Human Ischemic Stroke. Circulation 1996; 94: 939-45
    • (1996) Circulation , vol.94 , pp. 939-945
    • Lindsberg, P.J.1
  • 60
    • 84896396086 scopus 로고    scopus 로고
    • Association of E-selectin gene polymorphism (S128R) with ischemic stroke and stroke subtypes
    • Roy S, Das S, Danaboina R, et al. Association of E-selectin gene polymorphism (S128R) with ischemic stroke and stroke subtypes. Inflammation 2014; 37: 599-603
    • (2014) Inflammation , vol.37 , pp. 599-603
    • Roy, S.1    Das, S.2    Danaboina, R.3
  • 61
    • 84874371257 scopus 로고    scopus 로고
    • Multiple Biomarkers for the Prediction of Ischemic Stroke: The PRIME Study. Arterioscler, Thromb
    • Prugger C, Luc G, Haas B, et al. Multiple Biomarkers for the Prediction of Ischemic Stroke: The PRIME Study. Arterioscler, Thromb, Vasc Biol 2013; 33: 659-66
    • (2013) Vasc Biol , vol.33 , pp. 659-666
    • Prugger, C.1    Luc, G.2    Haas, B.3
  • 62
    • 0027209421 scopus 로고
    • Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
    • Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell 1993; 74: 541-54
    • (1993) Cell , vol.74 , pp. 541-554
    • Mayadas, T.N.1    Johnson, R.C.2    Rayburn, H.3    Hynes, R.O.4    Wagner, D.D.5
  • 63
    • 0033662074 scopus 로고    scopus 로고
    • Postischemic cerebrovascular E-selectin expression mediates tissue injury in murine stroke
    • Huang J, Choudhri TF, Winfree CJ, et al. Postischemic cerebrovascular E-selectin expression mediates tissue injury in murine stroke. Stroke 2000; 31: 3047-53
    • (2000) Stroke , vol.31 , pp. 3047-3053
    • Huang, J.1    Choudhri, T.F.2    Winfree, C.J.3
  • 64
    • 84868194281 scopus 로고    scopus 로고
    • E-selectin deficiency attenuates brain ischemia in mice
    • Ma X-J, Cheng J-W, Zhang J, et al. E-selectin deficiency attenuates brain ischemia in mice. CNS Neurosci Ther 2012; 18: 903-8
    • (2012) CNS Neurosci Ther , vol.18 , pp. 903-908
    • Ma, X.-J.1    Cheng, J.-W.2    Zhang, J.3
  • 65
    • 0037112549 scopus 로고    scopus 로고
    • HuEP5C7 as a humanized monoclonal Anti-E/P-selectin neurovascular protective strategy in a blinded placebo-controlled trial of nonhuman primate stroke
    • Mocco J, Choudhri T, Huang J, et al. HuEP5C7 as a humanized monoclonal Anti-E/P-selectin neurovascular protective strategy in a blinded placebo-controlled trial of nonhuman primate stroke. Circulation Res 2002; 91: 907-14
    • (2002) Circulation Res , vol.91 , pp. 907-914
    • Mocco, J.1    Choudhri, T.2    Huang, J.3
  • 66
    • 0027200051 scopus 로고
    • Monoclonal antibody to the ICAM-1 adhesion site reduces neurological damage in a rabbit cerebral embolism stroke model
    • Bowes MP, Zivin JA, Rothlein R. Monoclonal antibody to the ICAM-1 adhesion site reduces neurological damage in a rabbit cerebral embolism stroke model. Exp Neurol 1993; 119: 215-9
    • (1993) Exp Neurol , vol.119 , pp. 215-219
    • Bowes, M.P.1    Zivin, J.A.2    Rothlein, R.3
  • 67
    • 0029096735 scopus 로고
    • Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the wistar rat
    • Zhang RL, Chopp M, Jiang N, et al. Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the wistar rat. Stroke 1995; 26: 1438-43
    • (1995) Stroke , vol.26 , pp. 1438-1443
    • Zhang, R.L.1    Chopp, M.2    Jiang, N.3
  • 68
    • 0242694372 scopus 로고    scopus 로고
    • Investigators ftAS. Acute stroke therapy by inhibition of neutrophils (ASTIN): An adaptive dose-response study of UK-279, 276 in acute ischemic stroke
    • Krams M, Lees KR, Hacke W, Grieve AP, Orgogozo J-M, Ford GA, Investigators ftAS. Acute stroke therapy by inhibition of neutrophils (ASTIN): an adaptive dose-response study of UK-279, 276 in acute ischemic stroke. Stroke 2003; 34: 2543-8
    • (2003) Stroke , vol.34 , pp. 2543-2548
    • Krams, M.1    Lees, K.R.2    Hacke, W.3    Grieve, A.P.4    Orgogozo, J.-M.5    Ford, G.A.6
  • 69
    • 0038796526 scopus 로고    scopus 로고
    • Overexpression of monocyte chemoattractant protein 1 in the brain exacerbates ischemic brain injury and is associated with recruitment of inflammatory cells
    • Chen Y, Hallenbeck JM, Ruetzler C, et al. Overexpression of monocyte chemoattractant protein 1 in the brain exacerbates ischemic brain injury and is associated with recruitment of inflammatory cells. J Cereb Blood Flow Metab 2003; 23: 748-55
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 748-755
    • Chen, Y.1    Hallenbeck, J.M.2    Ruetzler, C.3
  • 70
    • 17644363389 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability
    • Stamatovic SM, Shakui P, Keep RF, et al. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab 2005; 25: 593-606
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 593-606
    • Stamatovic, S.M.1    Shakui, P.2    Keep, R.F.3
  • 71
    • 0036228047 scopus 로고    scopus 로고
    • Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury
    • Soriano SG, Amaravadi LS, Wang YF, et al. Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury. J Neuroimmunol 2002; 125: 59-65
    • (2002) J Neuroimmunol , vol.125 , pp. 59-65
    • Soriano, S.G.1    Amaravadi, L.S.2    Wang, Y.F.3
  • 72
  • 74
    • 84882611675 scopus 로고    scopus 로고
    • The role of inflammation and interleukin-1 in acute cerebrovascular disease
    • Galea J, Brough D. The role of inflammation and interleukin-1 in acute cerebrovascular disease. J Inflamm Res 2013; 6: 121-8
    • (2013) J Inflamm Res , vol.6 , pp. 121-128
    • Galea, J.1    Brough, D.2
  • 75
    • 0036138936 scopus 로고    scopus 로고
    • Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor
    • Touzani O, Boutin H, LeFeuvre R, et al. Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor. J Neurosci 2002; 22: 38-43
    • (2002) J Neurosci , vol.22 , pp. 38-43
    • Touzani, O.1    Boutin, H.2    Lefeuvre, R.3
  • 76
    • 0032978333 scopus 로고    scopus 로고
    • The progression and topographic distribution of interleukin-1[beta] expression after permanent middle cerebral artery occlusion in the rat
    • Davies CA, Loddick SA, Toulmond S, Stroemer RP, Hunt J, Rothwell NJ. The progression and topographic distribution of interleukin-1[beta] expression after permanent middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1999; 19: 87-98
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 87-98
    • Davies, C.A.1    Loddick, S.A.2    Toulmond, S.3    Stroemer, R.P.4    Hunt, J.5    Rothwell, N.J.6
  • 77
    • 84907028877 scopus 로고    scopus 로고
    • Early reperfusion injury is associated to MMP2 and IL-1 elevation in cortical neurons of rats subjected to middle cerebral artery occlusion
    • Amantea D, Certo M, Russo R, Bagetta G, Corasaniti MT, Tassorelli C. Early reperfusion injury is associated to MMP2 and IL-1 elevation in cortical neurons of rats subjected to middle cerebral artery occlusion. Neuroscience 2014; 277: 755-63
    • (2014) Neuroscience , vol.277 , pp. 755-763
    • Amantea, D.1    Certo, M.2    Russo, R.3    Bagetta, G.4    Corasaniti, M.T.5    Tassorelli, C.6
  • 79
    • 25444517949 scopus 로고    scopus 로고
    • A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients
    • Emsley HCA, Smith CJ, Georgiou RF, et al. A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients. J Neurol Neurosurg Psychiatry 2005; 76: 1366-72
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1366-1372
    • Emsley, H.1    Smith, C.J.2    Georgiou, R.F.3
  • 80
    • 84899899588 scopus 로고    scopus 로고
    • Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: A phase II randomized control trial
    • Helmy A, Guilfoyle MR, Carpenter KLH, Pickard JD, Menon DK, Hutchinson PJ. Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial. J Cereb Blood Flow Metab 2014; 34: 845-51
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 845-851
    • Helmy, A.1    Guilfoyle, M.R.2    Carpenter, K.3    Pickard, J.D.4    Menon, D.K.5    Hutchinson, P.J.6
  • 81
    • 84892171189 scopus 로고    scopus 로고
    • The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: A phase II randomised controlled trial
    • Singh N, Hopkins S, Hulme S, et al. The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial. J Neuroinflamm 2014; 11: 1-8
    • (2014) J Neuroinflamm , vol.11 , pp. 1-8
    • Singh, N.1    Hopkins, S.2    Hulme, S.3
  • 82
    • 22244468321 scopus 로고    scopus 로고
    • Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: Possible involvement of Stat3 activation in the protection of neurons
    • Yamashita T, Sawamoto K, Suzuki S, et al. Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. J Neurochem 2005; 94: 459-68
    • (2005) J Neurochem , vol.94 , pp. 459-468
    • Yamashita, T.1    Sawamoto, K.2    Suzuki, S.3
  • 83
    • 84860129424 scopus 로고    scopus 로고
    • Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability
    • Yan J, Greer JM, McCombe PA. Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability. J Neuroimmunol 2012; 246: 78-84
    • (2012) J Neuroimmunol , vol.246 , pp. 78-84
    • Yan, J.1    Greer, J.M.2    McCombe, P.A.3
  • 84
    • 54849409185 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPAR) differently modulate the interleukin-6 expression in the peri-infarct cortical tissue in the acute and delayed phases of cerebral ischaemia
    • Patzer A, Zhao Y, Stöck I, Gohlke P, Herdegen T, Culman J. Peroxisome proliferator-activated receptors (PPAR) differently modulate the interleukin-6 expression in the peri-infarct cortical tissue in the acute and delayed phases of cerebral ischaemia. Eur J Neurosci 2008; 28: 1786-94
    • (2008) Eur J Neurosci , vol.28 , pp. 1786-1794
    • Patzer, A.1    Zhao, Y.2    Stöck, I.3    Gohlke, P.4    Herdegen, T.5    Culman, J.6
  • 85
    • 0031894808 scopus 로고    scopus 로고
    • Cerebral Interleukin-6 Is Neuroprotective During Permanent Focal Cerebral Ischemia in the Rat
    • Loddick SA, Turnbull AV, Rothwell NJ. Cerebral Interleukin-6 Is Neuroprotective During Permanent Focal Cerebral Ischemia in the Rat. J Cereb Blood Flow Metab 1998; 18: 176-9
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 176-179
    • Loddick, S.A.1    Turnbull, A.V.2    Rothwell, N.J.3
  • 86
    • 0028292231 scopus 로고
    • Tumor necrosis factoralpha expression in ischemic neurons
    • Liu T, Clark RK, McDonnell PC, et al. Tumor necrosis factoralpha expression in ischemic neurons. Stroke 1994; 25: 1481-8
    • (1994) Stroke , vol.25 , pp. 1481-1488
    • Liu, T.1    Clark, R.K.2    McDonnell, P.C.3
  • 87
    • 0034892418 scopus 로고    scopus 로고
    • Evolution of cerebral tumor necrosis factorproduction during human ischemic stroke
    • Sairanen T, Carpén O, Karjalainen-Lindsberg ML, et al. Evolution of cerebral tumor necrosis factorproduction during human ischemic stroke. Stroke 2001; 32: 1750-8
    • (2001) Stroke , vol.32 , pp. 1750-1758
    • Sairanen, T.1    Carpén, O.2    Karjalainen-Lindsberg, M.L.3
  • 88
    • 0032557738 scopus 로고    scopus 로고
    • Inhibition of TNF attenuates infarct volume and ICAM 1 expression in ischemic mouse brain
    • Yang G-Y, Gong C, Qin Z, Ye W, Mao Y, Bertz AL. Inhibition of TNF attenuates infarct volume and ICAM 1 expression in ischemic mouse brain. Neuro Rep 1998; 9: 2131-4
    • (1998) Neuro Rep , vol.9 , pp. 2131-2134
    • Yang, G.-Y.1    Gong, C.2    Qin, Z.3    Ye, W.4    Mao, Y.5    Bertz, A.L.6
  • 89
    • 0030976856 scopus 로고    scopus 로고
    • Tumor necrosis factor: A mediator of focal ischemic brain injury
    • Barone FC, Arvin B, White RF, et al. Tumor necrosis factor: A mediator of focal ischemic brain injury. Stroke 1997; 28: 1233-44
    • (1997) Stroke , vol.28 , pp. 1233-1244
    • Barone, F.C.1    Arvin, B.2    White, R.F.3
  • 92
    • 84889095882 scopus 로고    scopus 로고
    • IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion
    • Perez-de Puig I, Miro F, Salas-Perdomo A, et al. IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion. J Cereb Blood Flow Metab 2013; 33: 1955-66
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 1955-1966
    • Perez-De Puig, I.1    Miro, F.2    Salas-Perdomo, A.3
  • 93
    • 84864357300 scopus 로고    scopus 로고
    • The neuroprotective functions of transforming growth factor beta proteins
    • Dobolyi A, Vincze C, Pál G, Lovas G. The neuroprotective functions of transforming growth factor beta proteins. Int J Mol Sci 2012; 13: 8219-58
    • (2012) Int J Mol Sci , vol.13 , pp. 8219-8258
    • Dobolyi, A.1    Vincze, C.2    Pál, G.3    Lovas, G.4
  • 94
    • 77957689347 scopus 로고    scopus 로고
    • TGF signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke
    • Doyle KP, Cekanaviciute E, Mamer LE, Buckwalter MS. TGF signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke. J Neuroinflamm 2010; 7: 62-62
    • (2010) J Neuroinflamm , vol.7 , pp. 62-67
    • Doyle, K.P.1    Cekanaviciute, E.2    Mamer, L.E.3    Buckwalter, M.S.4
  • 95
    • 0035965657 scopus 로고    scopus 로고
    • J K. 2-Adrenoceptor stimulation enhances latent transforming growth factor-binding protein-1 and transforming growth factor1 expression in rat hippocampus after transient forebrain ischemia
    • Zhu Y, Culmsee C, Roth-Eichhorn S, J K. 2-Adrenoceptor stimulation enhances latent transforming growth factor-binding protein-1 and transforming growth factor1 expression in rat hippocampus after transient forebrain ischemia. Neuroscience 2001; 107(4): 593-602
    • (2001) Neuroscience , vol.107 , Issue.4 , pp. 593-602
    • Zhu, Y.1    Culmsee, C.2    Roth-Eichhorn, S.3
  • 96
    • 0032402337 scopus 로고    scopus 로고
    • Microglia and macrophages are major sources of locally produced transforming growth factor-1 after transient middle cerebral artery occlusion in rats
    • Lehrmann E, Kiefer R, Christensen T, et al. Microglia and macrophages are major sources of locally produced transforming growth factor-1 after transient middle cerebral artery occlusion in rats. Glia 1998; 24: 437-48
    • (1998) Glia , vol.24 , pp. 437-448
    • Lehrmann, E.1    Kiefer, R.2    Christensen, T.3
  • 97
    • 0035130526 scopus 로고    scopus 로고
    • Reduction of inflammatory response in the mouse brain with adenoviral-mediated transforming growth factor1 Expression
    • Pang L, Ye W, Che X-M, Roessler BJ, Betz AL, Yang G-Y. Reduction of inflammatory response in the mouse brain with adenoviral-mediated transforming growth factor1 Expression. Stroke 2001; 32: 544-552
    • (2001) Stroke , vol.32 , pp. 544-552
    • Pang, L.1    Ye, W.2    Che, X.-M.3    Roessler, B.J.4    Betz, A.L.5    Yang, G.-Y.6
  • 98
    • 84867316100 scopus 로고    scopus 로고
    • Time Course, distribution and cell types of induction of transforming growth factor betas following middle cerebral artery occlusion in the rat brain
    • Pál G, Vincze C, Renner É, et al. Time Course, distribution and cell types of induction of transforming growth factor betas following middle cerebral artery occlusion in the rat brain. PLoS One 2012; 7(10): e46731
    • (2012) Plos One , vol.7 , Issue.10
    • Pál, G.1    Vincze, C.2    Renner, É.3
  • 99
    • 0028329252 scopus 로고
    • Neuronal rescue with transforming growth factor-[beta]1 after hypoxic-ischaemic brain injury
    • McNeill H, Williams C, Guan J, et al. Neuronal rescue with transforming growth factor-[beta]1 after hypoxic-ischaemic brain injury. NeuroReport 1994; 5: 901-4
    • (1994) Neuroreport , vol.5 , pp. 901-904
    • McNeill, H.1    Williams, C.2    Guan, J.3
  • 100
    • 17544366612 scopus 로고    scopus 로고
    • A Transforming growth factor-[beta] antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury
    • Ruocco A, Nicole O, Docagne F, et al. A Transforming growth factor-[beta] antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury. J Cereb Blood Flow Metab 1999; 19: 1345-53
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1345-1353
    • Ruocco, A.1    Nicole, O.2    Docagne, F.3
  • 101
    • 33746191796 scopus 로고    scopus 로고
    • Neuroprotection by ovarian hormones in animal models of neurological disease
    • Hoffman G, Merchenthaler I, Zup S. Neuroprotection by ovarian hormones in animal models of neurological disease. Endocrine 2006; 29: 217-31
    • (2006) Endocrine , vol.29 , pp. 217-231
    • Hoffman, G.1    Merchenthaler, I.2    Zup, S.3
  • 102
    • 0026714746 scopus 로고
    • Time lapse study of neurite growth in hypothalamic dissociated neurons in culture: SEX differences and estrogen effects
    • Díaz H, Lorenzo A, Carrer HF, Cáceres A. Time lapse study of neurite growth in hypothalamic dissociated neurons in culture: SEX differences and estrogen effects. J Neurosci Res 1992; 33: 266-81
    • (1992) J Neurosci Res , vol.33 , pp. 266-281
    • Díaz, H.1    Lorenzo, A.2    Carrer, H.F.3    Cáceres, A.4
  • 103
    • 78650014999 scopus 로고    scopus 로고
    • Organized for sex steroid hormones and the developing hypothalamus
    • Lenz KM, McCarthy MM. Organized for sex steroid hormones and the developing hypothalamus. Eur J Neurosci 2010; 32: 2096-104
    • (2010) Eur J Neurosci , vol.32 , pp. 2096-2104
    • Lenz, K.M.1    McCarthy, M.M.2
  • 104
    • 0033977930 scopus 로고    scopus 로고
    • Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling
    • Beyer C, Karolczak M. Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling. J Neurosci Res 2000; 59: 107-116
    • (2000) J Neurosci Res , vol.59 , pp. 107-116
    • Beyer, C.1    Karolczak, M.2
  • 105
    • 33745837449 scopus 로고    scopus 로고
    • Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell
    • Tsutsui K. Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell. Cerebellum 2006; 5: 89-96
    • (2006) Cerebellum , vol.5 , pp. 89-96
    • Tsutsui, K.1
  • 106
    • 84864690494 scopus 로고    scopus 로고
    • Neurosteroid biosynthesis and action during cerebellar development
    • Tsutsui K. Neurosteroid biosynthesis and action during cerebellar development. Cerebellum 2012; 11: 414-5
    • (2012) Cerebellum , vol.11 , pp. 414-415
    • Tsutsui, K.1
  • 107
    • 78349298648 scopus 로고    scopus 로고
    • Roles of 17b-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus
    • Bender RA, Zhou L, Wilkars W, et al. Roles of 17b-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. Cerebral Cortex 2010; 20(12): 2985-95
    • (2010) Cerebral Cortex , vol.20 , Issue.12 , pp. 2985-2995
    • Bender, R.A.1    Zhou, L.2    Wilkars, W.3
  • 108
    • 33846265875 scopus 로고    scopus 로고
    • Astrocyte-derived estrogen enhances synapse formation and synaptic transmission between cultured neonatal rat cortical neurons
    • Hu R, Cai WQ, Wu XG, Yang Z. Astrocyte-derived estrogen enhances synapse formation and synaptic transmission between cultured neonatal rat cortical neurons. Neuroscience 2007; 144: 1229-40
    • (2007) Neuroscience , vol.144 , pp. 1229-1240
    • Hu, R.1    Cai, W.Q.2    Wu, X.G.3    Yang, Z.4
  • 109
    • 84861183295 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: Recent advances
    • Arevalo MA, Ruiz-Palmero I, Scerbo MJ, et al. Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: Recent advances. J Steroid Biochem Mol Biol 2012; 131: 52-6
    • (2012) J Steroid Biochem Mol Biol , vol.131 , pp. 52-56
    • Arevalo, M.A.1    Ruiz-Palmero, I.2    Scerbo, M.J.3
  • 110
    • 67349113118 scopus 로고    scopus 로고
    • Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus
    • Fester L, Zhou L, Bütow A, et al. Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus. Hippocampus 2009; 19: 692-705
    • (2009) Hippocampus , vol.19 , pp. 692-705
    • Fester, L.1    Zhou, L.2    Bütow, A.3
  • 111
    • 3042717140 scopus 로고    scopus 로고
    • Hippocampal synapses depend on hippocampal estrogen synthesis
    • Kretz O, Fester L, Wehrenberg U, Zhou L, et al. Hippocampal synapses depend on hippocampal estrogen synthesis. J Neurosci 2004; 24(26): 5913-21
    • (2004) J Neurosci , vol.24 , Issue.26 , pp. 5913-5921
    • Kretz, O.1    Fester, L.2    Wehrenberg, U.3    Zhou, L.4
  • 112
    • 33749412430 scopus 로고    scopus 로고
    • Oestrogen synthesis in the hippocampus: Role in axon outgrowth
    • Von Schassen C, Fester L, Prange-Kiel J, et al. Oestrogen synthesis in the hippocampus: Role in axon outgrowth. J Neuroendocrinol 2006; 18: 847-56
    • (2006) J Neuroendocrinol , vol.18 , pp. 847-856
    • Von Schassen, C.1    Fester, L.2    Prange-Kiel, J.3
  • 113
    • 34548446343 scopus 로고    scopus 로고
    • Brain aromatase: Roles in reproduction and neuroprotection
    • Roselli CF. Brain aromatase: Roles in reproduction and neuroprotection. J Steroid Biochem Mol Biol 2007; 106: 143-50
    • (2007) J Steroid Biochem Mol Biol , vol.106 , pp. 143-150
    • Roselli, C.F.1
  • 114
    • 77449090238 scopus 로고    scopus 로고
    • Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor alpha to estrogen-responsive elements
    • Hewitt SC, Li Y, Li L, Korach KS. Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor alpha to estrogen-responsive elements. J Biol Chem 2010; 285: 2676-85
    • (2010) J Biol Chem , vol.285 , pp. 2676-2685
    • Hewitt, S.C.1    Li, Y.2    Li, L.3    Korach, K.S.4
  • 115
    • 12144272164 scopus 로고    scopus 로고
    • Mechanisms of membrane estrogen receptor-alpha-mediated rapid stimulation of Ca2+ levels and prolactin release in a pituitary cell line
    • Bulayeva NN, Wozniak AL, Lash LL, Watson CS. Mechanisms of membrane estrogen receptor-alpha-mediated rapid stimulation of Ca2+ levels and prolactin release in a pituitary cell line. Am J Physiol Endocrinol Metab 2005; 288: E388-97
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. EE97-E388
    • Bulayeva, N.N.1    Wozniak, A.L.2    Lash, L.L.3    Watson, C.S.4
  • 116
  • 117
    • 0023664141 scopus 로고
    • Molecular cloning and charcterization of rat estrogen receptor cDNA
    • Koike S, Sakai M, Muramatsu M. Molecular cloning and charcterization of rat estrogen receptor cDNA. Nucleic Acids Res 1987; 15(6): 2499-513
    • (1987) Nucleic Acids Res , vol.15 , Issue.6 , pp. 2499-2513
    • Koike, S.1    Sakai, M.2    Muramatsu, M.3
  • 119
    • 39749152787 scopus 로고    scopus 로고
    • Activation of estrogen receptor-[beta]regulates hippocampal synaptic plasticity and improves memory
    • Liu F, Day M, Muniz LC, Bitran D, et al. Activation of estrogen receptor-[beta]regulates hippocampal synaptic plasticity and improves memory. Nat Neurosci 2008; 11: 334-43
    • (2008) Nat Neurosci , vol.11 , pp. 334-343
    • Liu, F.1    Day, M.2    Muniz, L.C.3    Bitran, D.4
  • 120
    • 0030726653 scopus 로고    scopus 로고
    • The distribution of estrogen receptormrna in forebrain regions of the estrogen receptor-a knockout mouse
    • Shughrue P, Scrimo P, Lane M, Askew R, Merchenthaler I. The distribution of estrogen receptormrna in forebrain regions of the estrogen receptor-a knockout mouse. Endocrinology 1997; 138(12): 5649-52
    • (1997) Endocrinology , vol.138 , Issue.12 , pp. 5649-5652
    • Shughrue, P.1    Scrimo, P.2    Lane, M.3    Askew, R.4    Merchenthaler, I.5
  • 121
    • 40749104202 scopus 로고    scopus 로고
    • Estrogen receptor beta in the brain: From form to function
    • Weiser MJ, Foradori CD, Handa RJ. Estrogen receptor beta in the brain: From form to function. Brain Res Rev 2008; 57: 309-20
    • (2008) Brain Res Rev , vol.57 , pp. 309-320
    • Weiser, M.J.1    Foradori, C.D.2    Handa, R.J.3
  • 123
    • 0032487057 scopus 로고    scopus 로고
    • Expression and neuropeptidergic characterization of estrogen receptors (ER and ER) throughout the rat brain: Anatomical evidence of distinct roles of each subtype
    • Laflamme N, Nappi RE, Drolet G, Labrie C, Rivest S. Expression and neuropeptidergic characterization of estrogen receptors (ER and ER) throughout the rat brain: Anatomical evidence of distinct roles of each subtype. J Neurobiol 1998; 36: 357-78
    • (1998) J Neurobiol , vol.36 , pp. 357-378
    • Laflamme, N.1    Nappi, R.E.2    Drolet, G.3    Labrie, C.4    Rivest, S.5
  • 124
    • 0035898854 scopus 로고    scopus 로고
    • Distribution of estrogen receptor immunoreactivity in the rat central nervous system
    • Shughrue PJ, Merchenthaler I. Distribution of estrogen receptor immunoreactivity in the rat central nervous system. J Comp Neurol 2001; 436: 64-81
    • (2001) J Comp Neurol , vol.436 , pp. 64-81
    • Shughrue, P.J.1    Merchenthaler, I.2
  • 125
    • 0037052637 scopus 로고    scopus 로고
    • Distribution and differences of estrogen receptor beta immunoreactivity in the brain of adult male and female rats
    • Zhang J-Q, Cai W-Q, Zhou D-S, Su B-Y. Distribution and differences of estrogen receptor beta immunoreactivity in the brain of adult male and female rats. Brain Res 2002; 935: 73-80
    • (2002) Brain Res , vol.935 , pp. 73-80
    • Zhang, J.-Q.1    Cai, W.-Q.2    Zhou, D.-S.3    Su, B.-Y.4
  • 126
    • 1642374926 scopus 로고    scopus 로고
    • Distribution of estrogen receptor alpha and beta immunoreactive profiles in the postnatal rat brain
    • Perez SE, Chen EY, Mufson EJ. Distribution of estrogen receptor alpha and beta immunoreactive profiles in the postnatal rat brain. Develop Brain Res 2003; 145: 117-39
    • (2003) Develop Brain Res , vol.145 , pp. 117-139
    • Perez, S.E.1    Chen, E.Y.2    Mufson, E.J.3
  • 127
    • 57749178899 scopus 로고    scopus 로고
    • Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
    • Safe S, Kim K. Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. J Mol Endocrinol 2008; 41: 263-75
    • (2008) J Mol Endocrinol , vol.41 , pp. 263-275
    • Safe, S.1    Kim, K.2
  • 128
    • 0031736649 scopus 로고    scopus 로고
    • Oestrogen receptor beta (ER beta)
    • Saunders PT. Oestrogen receptor beta (ER beta). Rev Reproduct 1998; 3(3): 164-71
    • (1998) Rev Reproduct , vol.3 , Issue.3 , pp. 164-171
    • Saunders, P.T.1
  • 130
    • 13044292640 scopus 로고    scopus 로고
    • Generation and reproductive phenotypes of mice lacking estrogen receptor b
    • Krege JH, Hodgin JB, Couse JF, et al. Generation and reproductive phenotypes of mice lacking estrogen receptor b. Proc Natl Acad Sci USA 1998; 95(26): 15677-82
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.26 , pp. 15677-15682
    • Krege, J.H.1    Hodgin, J.B.2    Couse, J.F.3
  • 131
    • 0035834004 scopus 로고    scopus 로고
    • Increased anxiety and synaptic plasticity in estrogen receptor b-deficient mice
    • Krezel W, Dupont S, Krust A, Chambon P, Chapman PF. Increased anxiety and synaptic plasticity in estrogen receptor b-deficient mice. Proc Natl Acad Sci USA 2001; 98(21): 12278-82
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.21 , pp. 12278-12282
    • Krezel, W.1    Dupont, S.2    Krust, A.3    Chambon, P.4    Chapman, P.F.5
  • 132
    • 12144263826 scopus 로고    scopus 로고
    • Lack of functional estrogen receptor b influences anxiety behavior and serotonin content in female mice
    • Imwalle DB, Gustafsson J-Ãk, Rissman EF. Lack of functional estrogen receptor b influences anxiety behavior and serotonin content in female mice. Physiol Behav 2005; 84: 157-63
    • (2005) Physiol Behav , vol.84 , pp. 157-163
    • Imwalle, D.B.1    J-Ãk, G.2    Rissman, E.F.3
  • 133
    • 0036346098 scopus 로고    scopus 로고
    • Estrogen receptor ß is involved in the anorectic action of estrogen
    • Liang Y-Q, Akishita M, Kim S, et al. Estrogen receptor ß is involved in the anorectic action of estrogen. Int J Obesity 2002; 26 (8): 1103-9
    • (2002) Int J Obesity , vol.26 , Issue.8 , pp. 1103-1109
    • Liang, Y.-Q.1    Akishita, M.2    Kim, S.3
  • 134
    • 77954243780 scopus 로고    scopus 로고
    • Interaction of estrogen receptors with insulin-like growth factor-I and Wnt signaling in the nervous system
    • Varea O, Arevalo M-A, Garrido JJ, Garcia-Segura LM, Wandosell F, Mendez P. Interaction of estrogen receptors with insulin-like growth factor-I and Wnt signaling in the nervous system. Steroids 2010; 75: 565-9
    • (2010) Steroids , vol.75 , pp. 565-569
    • Varea, O.1    Arevalo, M.-A.2    Garrido, J.J.3    Garcia-Segura, L.M.4    Wandosell, F.5    Mendez, P.6
  • 135
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • Filardo EJ, Quinn JA, Frackelton AR, Jr., Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol 2002; 16: 70-84
    • (2002) Mol Endocrinol , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton, A.R.3    Bland, K.I.4
  • 136
    • 25144483917 scopus 로고    scopus 로고
    • GPR30: A seven-transmembrane-spanning estrogen receptor that triggers EGF release
    • Filardo EJ, Thomas P. GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release. Trends Endocrinol Metab 2005; 16(8): 362-7
    • (2005) Trends Endocrinol Metab , vol.16 , Issue.8 , pp. 362-367
    • Filardo, E.J.1    Thomas, P.2
  • 139
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005; 146: 624-32
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 140
    • 0142151032 scopus 로고    scopus 로고
    • Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C
    • Qiu J, Bosch MA, Tobias SC, et al. Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C. J Neurosci 2003; 23: 9529-40
    • (2003) J Neurosci , vol.23 , pp. 9529-9540
    • Qiu, J.1    Bosch, M.A.2    Tobias, S.C.3
  • 141
    • 77649153329 scopus 로고    scopus 로고
    • Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats
    • Lebesgue D, Traub M, De Butte-Smith M, et al. Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats. PLoS One 2010; 5(1): e8642
    • (2010) Plos One , vol.5 , Issue.1
    • Lebesgue, D.1    Traub, M.2    De Butte-Smith, M.3
  • 142
    • 0034802322 scopus 로고    scopus 로고
    • Cell localization, physiology, and nongenomic actions of estrogen receptors
    • Levin ER. Cell localization, physiology, and nongenomic actions of estrogen receptors. J Appl Physiol 2001; 91(4): 1860-7
    • (2001) J Appl Physiol , vol.91 , Issue.4 , pp. 1860-1867
    • Levin, E.R.1
  • 143
    • 33846813959 scopus 로고    scopus 로고
    • The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro
    • Mann V, Huber C, Kogianni G, Collins F, Noble B. The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro. Bone 2007; 40: 674-84
    • (2007) Bone , vol.40 , pp. 674-684
    • Mann, V.1    Huber, C.2    Kogianni, G.3    Collins, F.4    Noble, B.5
  • 144
    • 73549090352 scopus 로고    scopus 로고
    • Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolism
    • He J, Cheng Q, Xie W. Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolism. Mol Endocrinol 2010; 24: 11-21
    • (2010) Mol Endocrinol , vol.24 , pp. 11-21
    • He, J.1    Cheng, Q.2    Xie, W.3
  • 145
    • 77951901129 scopus 로고    scopus 로고
    • Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics
    • Huang P, Chandra V, Rastinejad F. Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annu Rev Physiol 2010; 72: 247-72
    • (2010) Annu Rev Physiol , vol.72 , pp. 247-272
    • Huang, P.1    Chandra, V.2    Rastinejad, F.3
  • 147
    • 0036813660 scopus 로고    scopus 로고
    • ER-X: A novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury
    • Toran-Allerand CD, Guan X, MacLusky NJ, et al. ER-X: A novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J Neurosci 2002; 22(19): 8391-401
    • (2002) J Neurosci , vol.22 , Issue.19 , pp. 8391-8401
    • Toran-Allerand, C.D.1    Guan, X.2    Maclusky, N.J.3
  • 148
    • 0344097487 scopus 로고    scopus 로고
    • Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: Convergence of estrogen and neurotrophin signaling pathways
    • Singh M, Setalo G, Jr., Guan X, Warren M, Toran-Allerand CD. Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways. J Neurosci 1999; 19: 1179-88
    • (1999) J Neurosci , vol.19 , pp. 1179-1188
    • Singh, M.1    Setalo, G.2    Guan, X.3    Warren, M.4    Toran-Allerand, C.D.5
  • 149
    • 0034193219 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons
    • Honda K, Sawada H, Kihara T, et al. Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons. J Neurosci Res 2000; 60: 321-7
    • (2000) J Neurosci Res , vol.60 , pp. 321-327
    • Honda, K.1    Sawada, H.2    Kihara, T.3
  • 150
    • 0037345781 scopus 로고    scopus 로고
    • Estrogen activates protein kinase C in neurons: Role in neuroprotection
    • Cordey M, Gundimeda U, Gopalakrishna R, Pike CJ. Estrogen activates protein kinase C in neurons: role in neuroprotection. J Neurochem 2003; 84: 1340-8
    • (2003) J Neurochem , vol.84 , pp. 1340-1348
    • Cordey, M.1    Gundimeda, U.2    Gopalakrishna, R.3    Pike, C.J.4
  • 151
    • 0037430850 scopus 로고    scopus 로고
    • Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulinlike growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain
    • Mendez P, Azcoitia I, Garcia-Segura LM. Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulinlike growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain. Brain Res Mol Brain Res 2003; 112(1-2): 170-6
    • (2003) Brain Res Mol Brain Res , vol.112 , Issue.1-2 , pp. 170-176
    • Mendez, P.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 152
    • 1642375658 scopus 로고    scopus 로고
    • Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus
    • Cardona-Gomez P, Perez M, Avila J, Garcia-Segura LM, Wandosell F. Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus. Mol Cell Neurosci 2004; 25: 363-73
    • (2004) Mol Cell Neurosci , vol.25 , pp. 363-373
    • Cardona-Gomez, P.1    Perez, M.2    Avila, J.3    Garcia-Segura, L.M.4    Wandosell, F.5
  • 154
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3Kinase/Akt cell survival pathway
    • Pap M, Cooper GM. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3Kinase/Akt cell survival pathway. J Biol Chem 1998; 273: 19929-32
    • (1998) J Biol Chem , vol.273 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 155
    • 0033178294 scopus 로고    scopus 로고
    • Estradiol modulates bcl-2 in cerebral ischemia: A potential role for estrogen receptors
    • Dubal DB, Shughrue PJ, Wilson ME, Merchenthaler I, Wise PM. Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. J Neurosci 1999; 19: 6385-93
    • (1999) J Neurosci , vol.19 , pp. 6385-6393
    • Dubal, D.B.1    Shughrue, P.J.2    Wilson, M.E.3    Merchenthaler, I.4    Wise, P.M.5
  • 156
    • 0033497678 scopus 로고    scopus 로고
    • Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: Evidence for a receptor-independent antioxidative mechanism
    • Culmsee C, Vedder H, Ravati A, et al. Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: evidence for a receptor-independent antioxidative mechanism. J Cereb Blood Flow Metab 1999; 19: 1263-9
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1263-1269
    • Culmsee, C.1    Vedder, H.2    Ravati, A.3
  • 157
    • 0035895957 scopus 로고    scopus 로고
    • The neuroprotective effects of phytoestrogens on amyloid beta proteininduced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons
    • Wang CN, Chi CW, Lin YL, Chen CF, Shiao YJ. The neuroprotective effects of phytoestrogens on amyloid beta proteininduced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. J Biol Chem 2001; 276: 5287-95
    • (2001) J Biol Chem , vol.276 , pp. 5287-5295
    • Wang, C.N.1    Chi, C.W.2    Lin, Y.L.3    Chen, C.F.4    Shiao, Y.J.5
  • 158
    • 0038281536 scopus 로고    scopus 로고
    • Estradiol exerts neuroprotective actions against ischemic brain injury: Insights derived from animal models
    • Wise P. Estradiol exerts neuroprotective actions against ischemic brain injury: insights derived from animal models. Endocrine 2003; 21: 11-5
    • (2003) Endocrine , vol.21 , pp. 11-15
    • Wise, P.1
  • 159
    • 11144354902 scopus 로고    scopus 로고
    • Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 betaestradiol-mediated neuroprotection
    • Yu X, Rajala RV, McGinnis JF, et al. Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 betaestradiol-mediated neuroprotection. J Biol Chem 2004; 279: 13086-94
    • (2004) J Biol Chem , vol.279 , pp. 13086-13094
    • Yu, X.1    Rajala, R.V.2    McGinnis, J.F.3
  • 160
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas JJ, Hernandez F, Gomez-Ramos P, Moran MA, Hen R, Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 2001; 20: 27-39
    • (2001) EMBO J , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 161
    • 0031946864 scopus 로고    scopus 로고
    • Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides
    • Xu H, Gouras GK, Greenfield JP, et al. Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nat Med 1998; 4: 447-51
    • (1998) Nat Med , vol.4 , pp. 447-451
    • Xu, H.1    Gouras, G.K.2    Greenfield, J.P.3
  • 163
    • 47549090307 scopus 로고    scopus 로고
    • Regulation of estrogen rapid signaling through arginine methylation by PRMT1
    • Le Romancer M, Treilleux I, Leconte N, et al. Regulation of estrogen rapid signaling through arginine methylation by PRMT1. Mol Cell 2008; 31: 212-21
    • (2008) Mol Cell , vol.31 , pp. 212-221
    • Le Romancer, M.1    Treilleux, I.2    Leconte, N.3
  • 165
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000; 103: 311-20
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 166
    • 0037456847 scopus 로고    scopus 로고
    • Links between signal transduction, transcription and adhesion in epithelial bud development
    • Jamora C, DasGupta R, Kocieniewski P, Fuchs E. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 2003; 422: 317-22
    • (2003) Nature , vol.422 , pp. 317-322
    • Jamora, C.1    Dasgupta, R.2    Kocieniewski, P.3    Fuchs, E.4
  • 167
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398: 422-6
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 168
    • 23344433876 scopus 로고    scopus 로고
    • Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine
    • Sansom OJ, Reed KR, van de Wetering M, et al. Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine. J Biol Chem 2005; 280: 28463-7
    • (2005) J Biol Chem , vol.280 , pp. 28463-28467
    • Sansom, O.J.1    Reed, K.R.2    Van De Wetering, M.3
  • 169
    • 0033545845 scopus 로고    scopus 로고
    • The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
    • Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 1999; 96: 5522-7
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5522-5527
    • Shtutman, M.1    Zhurinsky, J.2    Simcha, I.3
  • 170
    • 0027736963 scopus 로고
    • Responses to Wnt signals in vertebrate embryos may involve changes in cell adhesion and cell movement
    • Moon RT, DeMarais A, Olson DJ. Responses to Wnt signals in vertebrate embryos may involve changes in cell adhesion and cell movement. J Cell Sci Suppl 1993; 17: 183-8
    • (1993) J Cell Sci Suppl , vol.17 , pp. 183-188
    • Moon, R.T.1    Demarais, A.2    Olson, D.J.3
  • 171
    • 12544252343 scopus 로고    scopus 로고
    • Beta-Catenin: A pivot between cell adhesion and Wnt signalling
    • Bienz M. beta-Catenin: a pivot between cell adhesion and Wnt signalling. Curr Biol 2005; 15: R64-7
    • (2005) Curr Biol , vol.15 , pp. RR4-R67
    • Bienz, M.1
  • 172
    • 28844439793 scopus 로고    scopus 로고
    • Interaction of Nuclear Receptors with Wnt/{beta}-catenin/Tcf Signalling: Wnt you like to know?
    • Mulholland DJ, Dedhar S, Coetzee GA, Nelson CC. Interaction of Nuclear Receptors with Wnt/{beta}-catenin/Tcf Signalling: Wnt you like to know? Endocr Rev 2005; 26(7): 898-915
    • (2005) Endocr Rev , vol.26 , Issue.7 , pp. 898-915
    • Mulholland, D.J.1    Dedhar, S.2    Coetzee, G.A.3    Nelson, C.C.4
  • 173
    • 33845355511 scopus 로고    scopus 로고
    • Diversity of LEF/TCF action in development and disease
    • Arce L, Yokoyama NN, Waterman ML. Diversity of LEF/TCF action in development and disease. Oncogene 2006; 25: 7492-504
    • (2006) Oncogene , vol.25 , pp. 7492-7504
    • Arce, L.1    Yokoyama, N.N.2    Waterman, M.L.3
  • 174
    • 33845351102 scopus 로고    scopus 로고
    • Transgenic Wnt/TCF pathway reporters: All you need is Lef?
    • Barolo S. Transgenic Wnt/TCF pathway reporters: all you need is Lef? Oncogene 2006; 25: 7505-11
    • (2006) Oncogene , vol.25 , pp. 7505-7511
    • Barolo, S.1
  • 175
    • 4644326231 scopus 로고    scopus 로고
    • Wnt/beta-catenin and estrogen signaling converge in vivo
    • Kouzmenko AP, Takeyama K, Ito S, et al. Wnt/beta-catenin and estrogen signaling converge in vivo. J Biol Chem 2004; 279: 40255-8
    • (2004) J Biol Chem , vol.279 , pp. 40255-40258
    • Kouzmenko, A.P.1    Takeyama, K.2    Ito, S.3
  • 176
    • 43049100383 scopus 로고    scopus 로고
    • Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen
    • Ray S, Xu F, Wang H, Das SK. Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. Mol Endocrinol 2008; 22: 1125-40
    • (2008) Mol Endocrinol , vol.22 , pp. 1125-1140
    • Ray, S.1    Xu, F.2    Wang, H.3    Das, S.K.4
  • 178
    • 77954243780 scopus 로고    scopus 로고
    • Interaction of estrogen receptors with insulin-like growth factor-I and Wnt signaling in the nervous system
    • Varea O, Arevalo MA, Garrido JJ, Garcia-Segura LM, Wandosell F, Mendez P. Interaction of estrogen receptors with insulin-like growth factor-I and Wnt signaling in the nervous system. Steroids 2010; 75: 565-9
    • (2010) Steroids , vol.75 , pp. 565-569
    • Varea, O.1    Arevalo, M.A.2    Garrido, J.J.3    Garcia-Segura, L.M.4    Wandosell, F.5    Mendez, P.6
  • 179
    • 51649110188 scopus 로고    scopus 로고
    • Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation
    • Zhang QG, Wang R, Khan M, Mahesh V, Brann DW. Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation. J Neurosci 2008; 28: 8430-41
    • (2008) J Neurosci , vol.28 , pp. 8430-8441
    • Zhang, Q.G.1    Wang, R.2    Khan, M.3    Mahesh, V.4    Brann, D.W.5
  • 180
    • 34347238583 scopus 로고    scopus 로고
    • Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane
    • Filardo E, Quinn J, Pang Y, Graeber C, Shaw S, Dong J, Thomas P. Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane. Endocrinology 2007; 148: 3236-45
    • (2007) Endocrinology , vol.148 , pp. 3236-3245
    • Filardo, E.1    Quinn, J.2    Pang, Y.3    Graeber, C.4    Shaw, S.5    Dong, J.6    Thomas, P.7
  • 181
    • 84924059680 scopus 로고    scopus 로고
    • The neuroprotective actions of oestradiol and oestrogen receptors
    • Arevalo MA, Azcoitia I, Garcia-Segura LM. The neuroprotective actions of oestradiol and oestrogen receptors. Nat Rev Neurosci 2015; 16: 17-29
    • (2015) Nat Rev Neurosci , vol.16 , pp. 17-29
    • Arevalo, M.A.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 182
    • 0036133869 scopus 로고    scopus 로고
    • Neurosteroids: Biochemistry and clinical significance
    • Mellon SH, Griffin LD. Neurosteroids: biochemistry and clinical significance. Trends Endocrinol Metab 2002; 13: 35-43
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 35-43
    • Mellon, S.H.1    Griffin, L.D.2
  • 183
    • 44249092777 scopus 로고    scopus 로고
    • Progesterone biosynthesis and action in the developing neuron
    • Tsutsui K. Progesterone biosynthesis and action in the developing neuron. Endocrinology 2008; 149: 2757-61
    • (2008) Endocrinology , vol.149 , pp. 2757-2761
    • Tsutsui, K.1
  • 184
    • 65449116901 scopus 로고    scopus 로고
    • Steroid biosynthesis within the frog brain: A model of neuroendocrine regulation
    • Do Rego JL, Seong JY, Burel D, et al. Steroid biosynthesis within the frog brain: a model of neuroendocrine regulation. Ann N Y Acad Sci 2009; 1163: 83-92
    • (2009) Ann N Y Acad Sci , vol.1163 , pp. 83-92
    • Do Rego, J.L.1    Seong, J.Y.2    Burel, D.3
  • 185
    • 84892874222 scopus 로고    scopus 로고
    • Revisiting the roles of progesterone and allopregnanolone in the nervous system: Resurgence of the progesterone receptors
    • Schumacher M, Mattern C, Ghoumari A, et al. Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors. Prog Neurobiol 2014; 113: 639
    • (2014) Prog Neurobiol , vol.113
    • Schumacher, M.1    Mattern, C.2    Ghoumari, A.3
  • 186
    • 0025239785 scopus 로고
    • Two distinct estrogenregulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner P, Krust A, Turcotte B, et al. Two distinct estrogenregulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. Embo J 1990; 9: 1603-14
    • (1990) Embo J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3
  • 187
    • 0023545241 scopus 로고
    • The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA
    • Conneely OM, Maxwell BL, Toft DO, Schrader WT, O'Malley BW. The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA. Biochem Biophys Res Commun 1987; 149: 493-501
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 493-501
    • Conneely, O.M.1    Maxwell, B.L.2    Toft, D.O.3    Schrader, W.T.4    O'malley, B.W.5
  • 189
    • 0037981375 scopus 로고    scopus 로고
    • Novel isoforms of the mRNA for human female sex steroid hormone receptors
    • Hirata S, Shoda T, Kato J, Hoshi K. Novel isoforms of the mRNA for human female sex steroid hormone receptors. J Steroid Biochem Mol Biol 2002; 83: 25-30
    • (2002) J Steroid Biochem Mol Biol , vol.83 , pp. 25-30
    • Hirata, S.1    Shoda, T.2    Kato, J.3    Hoshi, K.4
  • 190
    • 0037732485 scopus 로고    scopus 로고
    • Isoform/variant mRNAs for sex steroid hormone receptors in humans
    • Hirata S, Shoda T, Kato J, Hoshi K. Isoform/variant mRNAs for sex steroid hormone receptors in humans. Trends Endocrinol Metab 2003; 14: 124-9
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 124-129
    • Hirata, S.1    Shoda, T.2    Kato, J.3    Hoshi, K.4
  • 191
    • 0037224484 scopus 로고    scopus 로고
    • Nongenomic actions of steroid hormones
    • Losel R, Wehling M. Nongenomic actions of steroid hormones. Nat Rev Mol Cell Biol 2003; 4: 46-56
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 46-56
    • Losel, R.1    Wehling, M.2
  • 192
    • 0037570621 scopus 로고    scopus 로고
    • Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification
    • Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol 2003; 23: 3763-73
    • (2003) Mol Cell Biol , vol.23 , pp. 3763-3773
    • Li, X.1    Wong, J.2    Tsai, S.Y.3    Tsai, M.J.4    O'malley, B.W.5
  • 193
    • 44249128152 scopus 로고    scopus 로고
    • Progestin receptor subtypes in the brain: The known and the unknown
    • Mani S. Progestin receptor subtypes in the brain: the known and the unknown. Endocrinology 2008; 149: 2750-6
    • (2008) Endocrinology , vol.149 , pp. 2750-2756
    • Mani, S.1
  • 194
    • 84916879629 scopus 로고    scopus 로고
    • Mechanism of Progesterone Receptor Action in the Brain
    • Pfaff DW, Arnold P, Etgen AM, Amsterdam: Academic Press
    • Mani K, O’Malley BW. Mechanism of Progesterone Receptor Action in the Brain. In: Pfaff DW, Arnold P, Etgen AM, Eds. Molecular Mechanisms of Hormone Actions on Behavior. Amsterdam: Academic Press 2009; pp. 375-411
    • (2009) Molecular Mechanisms of Hormone Actions on Behavior , pp. 375-411
    • Mani, K.1    O’Malley, B.W.2
  • 195
    • 84916884425 scopus 로고    scopus 로고
    • Progesterone synthesis, Metabolism, Mechanisms of action, and effects in the nervous system
    • Pfaff DW, Arnold AP, Etgen AM, Amsterdam: Academic Press
    • Schumacher M, Guennoun R. Progesterone synthesis, Metabolism, Mechanisms of action, and effects in the nervous system. In: Pfaff DW, Arnold AP, Etgen AM. Eds. Molecular mechanisms of hormone actions on behavior. Amsterdam: Academic Press 2009; pp. 413-452
    • (2009) Molecular Mechanisms of Hormone Actions on Behavior , pp. 413-452
    • Schumacher, M.1    Guennoun, R.2
  • 196
    • 79960099287 scopus 로고    scopus 로고
    • Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
    • Xu J, Zeng C, Chu W, et al. Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site. Nat Commun 2011; 2: 380
    • (2011) Nat Commun , vol.2
    • Xu, J.1    Zeng, C.2    Chu, W.3
  • 197
    • 0344885580 scopus 로고    scopus 로고
    • Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
    • Zhu Y, Bond J, Thomas P. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc Natl Acad Sci USA 2003; 100: 2237-42
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2237-2242
    • Zhu, Y.1    Bond, J.2    Thomas, P.3
  • 198
    • 84871689323 scopus 로고    scopus 로고
    • Characterization, neurosteroid binding and brain distribution of human membrane progesterone receptors delta and {epsilon} (MPRdelta and mPR{epsilon}) and mPRdelta involvement in neurosteroid inhibition of apoptosis
    • Pang Y, Dong J, Thomas P. Characterization, neurosteroid binding and brain distribution of human membrane progesterone receptors delta and {epsilon} (mPRdelta and mPR{epsilon}) and mPRdelta involvement in neurosteroid inhibition of apoptosis. Endocrinology 2013; 154: 283-95
    • (2013) Endocrinology , vol.154 , pp. 283-295
    • Pang, Y.1    Dong, J.2    Thomas, P.3
  • 199
    • 84871854025 scopus 로고    scopus 로고
    • Distribution of membrane progesterone receptor alpha in the male mouse and rat brain and its regulation after traumatic brain injury
    • Meffre D, Labombarda F, Delespierre B, et al. Distribution of membrane progesterone receptor alpha in the male mouse and rat brain and its regulation after traumatic brain injury. Neuroscience 2013; 231: 111-24
    • (2013) Neuroscience , vol.231 , pp. 111-124
    • Meffre, D.1    Labombarda, F.2    Delespierre, B.3
  • 200
    • 84865408327 scopus 로고    scopus 로고
    • Distribution and estrogen regulation of membrane progesterone receptor-beta in the female rat brain
    • Zuloaga DG, Yahn SL, Pang Y, et al. Distribution and estrogen regulation of membrane progesterone receptor-beta in the female rat brain. Endocrinology 2012; 153: 4432-43
    • (2012) Endocrinology , vol.153 , pp. 4432-4443
    • Zuloaga, D.G.1    Yahn, S.L.2    Pang, Y.3
  • 201
    • 74449084771 scopus 로고    scopus 로고
    • Membrane progesterone receptors localization in the mouse spinal cord
    • Labombarda F, Meffre D, Delespierre B, et al. Membrane progesterone receptors localization in the mouse spinal cord. Neuroscience 2010; 166: 94-106
    • (2010) Neuroscience , vol.166 , pp. 94-106
    • Labombarda, F.1    Meffre, D.2    Delespierre, B.3
  • 203
    • 84896854272 scopus 로고    scopus 로고
    • Enhancement of cell surface expression and receptor functions of membrane progestin receptor alpha (MPRalpha) by progesterone receptor membrane component 1 (PGRMC1): Evidence for a role of PGRMC1 as an adaptor protein for steroid receptors
    • Thomas P, Pang Y, Dong J. Enhancement of cell surface expression and receptor functions of membrane progestin receptor alpha (mPRalpha) by progesterone receptor membrane component 1 (PGRMC1): evidence for a role of PGRMC1 as an adaptor protein for steroid receptors. Endocrinology 2014; 155: 1107-19
    • (2014) Endocrinology , vol.155 , pp. 1107-1119
    • Thomas, P.1    Pang, Y.2    Dong, J.3
  • 204
    • 0032562712 scopus 로고    scopus 로고
    • Progesterone regulates transcription of the p21(WAF1) cyclindependent kinase inhibitor gene through Sp1 and CBP/p300
    • Owen GI, Richer JK, Tung L, Takimoto G, Horwitz KB. Progesterone regulates transcription of the p21(WAF1) cyclindependent kinase inhibitor gene through Sp1 and CBP/p300. J Biol Chem 1998; 273: 10696-701
    • (1998) J Biol Chem , vol.273 , pp. 10696-10701
    • Owen, G.I.1    Richer, J.K.2    Tung, L.3    Takimoto, G.4    Horwitz, K.B.5
  • 205
    • 0033047771 scopus 로고    scopus 로고
    • Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family
    • Stoecklin E, Wissler M, Schaetzle D, Pfitzner E, Groner B. Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family. J Steroid Biochem Mol Biol 1999; 69: 195-204
    • (1999) J Steroid Biochem Mol Biol , vol.69 , pp. 195-204
    • Stoecklin, E.1    Wissler, M.2    Schaetzle, D.3    Pfitzner, E.4    Groner, B.5
  • 206
    • 3543002856 scopus 로고    scopus 로고
    • Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (Progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter
    • Cicatiello L, Addeo R, Sasso A, et al. Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter. Mol Cell Biol 2004; 24: 7260-74
    • (2004) Mol Cell Biol , vol.24 , pp. 7260-7274
    • Cicatiello, L.1    Addeo, R.2    Sasso, A.3
  • 207
    • 34249800111 scopus 로고    scopus 로고
    • Differential hormonal regulation and function of progesterone receptor isoforms in normal adult mouse mammary gland
    • Aupperlee MD, Haslam SZ. Differential hormonal regulation and function of progesterone receptor isoforms in normal adult mouse mammary gland. Endocrinology 2007; 148: 2290-300
    • (2007) Endocrinology , vol.148 , pp. 2290-2300
    • Aupperlee, M.D.1    Haslam, S.Z.2
  • 209
    • 33846581488 scopus 로고    scopus 로고
    • The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle
    • Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP. The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol 2007; 21: 359-75
    • (2007) Mol Endocrinol , vol.21 , pp. 359-375
    • Boonyaratanakornkit, V.1    McGowan, E.2    Sherman, L.3    Mancini, M.A.4    Cheskis, B.J.5    Edwards, D.P.6
  • 210
    • 34247557419 scopus 로고    scopus 로고
    • Receptor mechanisms mediating non-genomic actions of sex steroids
    • Boonyaratanakornkit V, Edwards DP. Receptor mechanisms mediating non-genomic actions of sex steroids. Semin Reprod Med 2007; 25: 139-53
    • (2007) Semin Reprod Med , vol.25 , pp. 139-153
    • Boonyaratanakornkit, V.1    Edwards, D.P.2
  • 212
    • 0034852802 scopus 로고    scopus 로고
    • Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases
    • Boonyaratanakornkit V, Scott MP, Ribon V, et al. Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. Mol Cell 2001; 8: 269-80
    • (2001) Mol Cell , vol.8 , pp. 269-280
    • Boonyaratanakornkit, V.1    Scott, M.P.2    Ribon, V.3
  • 213
    • 0032036584 scopus 로고    scopus 로고
    • Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor
    • Migliaccio A, Piccolo D, Castoria G, et al. Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor. EMBO J 1998; 17: 2008-18
    • (1998) EMBO J , vol.17 , pp. 2008-2018
    • Migliaccio, A.1    Piccolo, D.2    Castoria, G.3
  • 214
    • 0344885581 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
    • Zhu Y, Rice CD, Pang Y, Pace M, Thomas P. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proc Natl Acad Sci USA 2003; 100: 2231-6
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2231-2236
    • Zhu, Y.1    Rice, C.D.2    Pang, Y.3    Pace, M.4    Thomas, P.5
  • 215
    • 41549091710 scopus 로고    scopus 로고
    • Characteristics of membrane progestin receptor alpha (MPRalpha) and progesterone membrane receptor component 1 (PGMRC1) and their roles in mediating rapid progestin actions
    • Thomas P. Characteristics of membrane progestin receptor alpha (mPRalpha) and progesterone membrane receptor component 1 (PGMRC1) and their roles in mediating rapid progestin actions. Front Neuroendocrinol 2008; 29: 292-312
    • (2008) Front Neuroendocrinol , vol.29 , pp. 292-312
    • Thomas, P.1
  • 216
    • 0037035590 scopus 로고    scopus 로고
    • Impact of progestins on estradiol potentiation of the glutamate calcium response
    • Nilsen J, Brinton RD. Impact of progestins on estradiol potentiation of the glutamate calcium response. Neuroreport 2002; 13: 825-30
    • (2002) Neuroreport , vol.13 , pp. 825-830
    • Nilsen, J.1    Brinton, R.D.2
  • 217
    • 0042337371 scopus 로고    scopus 로고
    • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
    • Nilsen J, Brinton RD. Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling. Proc Natl Acad Sci USA 2003; 100: 10506-11
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10506-10511
    • Nilsen, J.1    Brinton, R.D.2
  • 218
    • 33845483366 scopus 로고    scopus 로고
    • Progesterone regulation of human granulosa/luteal cell viability by an RU486independent mechanism
    • Engmann L, Losel R, Wehling M, Peluso JJ. Progesterone regulation of human granulosa/luteal cell viability by an RU486independent mechanism. J Clin Endocrinol Metab 2006; 91: 49628
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 49628
    • Engmann, L.1    Losel, R.2    Wehling, M.3    Peluso, J.J.4
  • 219
    • 1942501006 scopus 로고    scopus 로고
    • Tonically active GABA A receptors: Modulating gain and maintaining the tone
    • Semyanov A, Walker MC, Kullmann DM, Silver RA. Tonically active GABA A receptors: modulating gain and maintaining the tone. Trends Neurosci 2004; 27: 262-9
    • (2004) Trends Neurosci , vol.27 , pp. 262-269
    • Semyanov, A.1    Walker, M.C.2    Kullmann, D.M.3    Silver, R.A.4
  • 220
    • 12744273084 scopus 로고    scopus 로고
    • Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin
    • Alldred MJ, Mulder-Rosi J, Lingenfelter SE, Chen G, Luscher B. Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin. J Neurosci 2005; 25: 594-603
    • (2005) J Neurosci , vol.25 , pp. 594-603
    • Alldred, M.J.1    Mulder-Rosi, J.2    Lingenfelter, S.E.3    Chen, G.4    Luscher, B.5
  • 221
    • 14844323722 scopus 로고    scopus 로고
    • Variations on an inhibitory theme: Phasic and tonic activation of GABA(A) receptors
    • Farrant M, Nusser Z. Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat Rev Neurosci 2005; 6: 215-29
    • (2005) Nat Rev Neurosci , vol.6 , pp. 215-229
    • Farrant, M.1    Nusser, Z.2
  • 222
    • 33644509236 scopus 로고    scopus 로고
    • Neuroactive steroids and inhibitory neurotransmission: Mechanisms of action and physiological relevance
    • Belelli D, Herd MB, Mitchell EA, et al. Neuroactive steroids and inhibitory neurotransmission: mechanisms of action and physiological relevance. Neuroscience 2006; 138: 821-9
    • (2006) Neuroscience , vol.138 , pp. 821-829
    • Belelli, D.1    Herd, M.B.2    Mitchell, E.A.3
  • 223
    • 33751314737 scopus 로고    scopus 로고
    • Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites
    • Hosie AM, Wilkins ME, da Silva HM, Smart TG. Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. Nature 2006; 444: 486-9
    • (2006) Nature , vol.444 , pp. 486-489
    • Hosie, A.M.1    Wilkins, M.E.2    Da Silva, H.M.3    Smart, T.G.4
  • 224
    • 67349125852 scopus 로고    scopus 로고
    • Neuroprotective actions of sex steroids in Parkinson's disease
    • Bourque M, Dluzen DE, Di Paolo T. Neuroprotective actions of sex steroids in Parkinson's disease. Front Neuroendocrinol 2009; 30: 142-57
    • (2009) Front Neuroendocrinol , vol.30 , pp. 142-157
    • Bourque, M.1    Dluzen, D.E.2    Di Paolo, T.3
  • 225
    • 84878498475 scopus 로고    scopus 로고
    • Estrogen receptors and ischemic neuroprotection: Who, what, where and when?
    • Schreihofer DA, Ma Y. Estrogen receptors and ischemic neuroprotection: Who, what, where and when? Brain Res 2013; 1514: 107-22
    • (2013) Brain Res , vol.1514 , pp. 107-122
    • Schreihofer, D.A.1    Ma, Y.2
  • 226
    • 25144462015 scopus 로고    scopus 로고
    • Role of nonfeminizing estrogens in brain protection from cerebral ischemia: An animal model of Alzheimer's disease neuropathology
    • Simpkins JW, Wen Y, Perez E, Yang S, Wang X. Role of nonfeminizing estrogens in brain protection from cerebral ischemia: an animal model of Alzheimer's disease neuropathology. Ann N Y Acad Sci 2005; 1052: 233-42
    • (2005) Ann N Y Acad Sci , vol.1052 , pp. 233-242
    • Simpkins, J.W.1    Wen, Y.2    Perez, E.3    Yang, S.4    Wang, X.5
  • 227
    • 1342330571 scopus 로고    scopus 로고
    • Neuroprotection by Estrogen in Animal Models of Global and Focal Ischemia
    • Merchenthaler I, Dellovade TL, Shughrue PJ. Neuroprotection by Estrogen in Animal Models of Global and Focal Ischemia. Ann New York Acad Sci 2003; 1007: 89-100
    • (2003) Ann New York Acad Sci , vol.1007 , pp. 89-100
    • Merchenthaler, I.1    Dellovade, T.L.2    Shughrue, P.J.3
  • 228
    • 84864809822 scopus 로고    scopus 로고
    • Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia
    • Perez-Alvarez MJ, Maza Mdel C, Anton M, Ordonez L, Wandosell F. Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia. J Neuroinflamm 2012; 9: 157
    • (2012) J Neuroinflamm , vol.9
    • Perez-Alvarez, M.J.1    Maza Mdel, C.2    Anton, M.3    Ordonez, L.4    Wandosell, F.5
  • 229
  • 230
    • 77956178214 scopus 로고    scopus 로고
    • Menopause and mitochondria: Windows into estrogen effects on Alzheimer's disease risk and therapy
    • Henderson VW, Brinton RD. Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy. Prog Brain Res 2010; 182: 77-96
    • (2010) Prog Brain Res , vol.182 , pp. 77-96
    • Henderson, V.W.1    Brinton, R.D.2
  • 232
    • 33750371447 scopus 로고    scopus 로고
    • Chemokines, mononuclear cells and the nervous system: Heaven (or hell) is in the details
    • Rebenko-Moll NM, Liu L, Cardona A, Ransohoff RM. Chemokines, mononuclear cells and the nervous system: heaven (or hell) is in the details. Curr Opin Immunol 2006; 18: 683-9
    • (2006) Curr Opin Immunol , vol.18 , pp. 683-689
    • Rebenko-Moll, N.M.1    Liu, L.2    Cardona, A.3    Ransohoff, R.M.4
  • 233
    • 33645868993 scopus 로고    scopus 로고
    • The endogenous estrogen status regulates microglia reactivity in animal models of neuroinflammation
    • Vegeto E, Belcredito S, Ghisletti S, Meda C, Etteri S, Maggi A. The endogenous estrogen status regulates microglia reactivity in animal models of neuroinflammation. Endocrinology 2006; 147(5): 2263-72
    • (2006) Endocrinology , vol.147 , Issue.5 , pp. 2263-2272
    • Vegeto, E.1    Belcredito, S.2    Ghisletti, S.3    Meda, C.4    Etteri, S.5    Maggi, A.6
  • 234
    • 51749112880 scopus 로고    scopus 로고
    • Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases
    • Vegeto E, Benedusi V, Maggi A. Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases. Front Neuroendocrinol 2008; 29: 507-19
    • (2008) Front Neuroendocrinol , vol.29 , pp. 507-519
    • Vegeto, E.1    Benedusi, V.2    Maggi, A.3
  • 235
    • 9244239174 scopus 로고    scopus 로고
    • Estrogen modulates microglial inflammatory mediator production via interactions with estrogen receptor b
    • Baker AE, Brautigam VM, Watters JJ. Estrogen modulates microglial inflammatory mediator production via interactions with estrogen receptor b. Endocrinology 2004; 145(11): 5021-32
    • (2004) Endocrinology , vol.145 , Issue.11 , pp. 5021-5032
    • Baker, A.E.1    Brautigam, V.M.2    Watters, J.J.3
  • 237
    • 0035869340 scopus 로고    scopus 로고
    • Estrogen prevents the lipopolysaccharide-induced inflammatory response in microglia
    • Vegeto E, Bonincontro C, Pollio G, et al. Estrogen prevents the lipopolysaccharide-induced inflammatory response in microglia. J Neurosci 2001; 21(6): 1809-18
    • (2001) J Neurosci , vol.21 , Issue.6 , pp. 1809-1818
    • Vegeto, E.1    Bonincontro, C.2    Pollio, G.3
  • 238
    • 20444477493 scopus 로고    scopus 로고
    • Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury
    • Pettus EH, Wright DW, Stein DG, Hoffman SW. Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury. Brain Res 2005; 1049 (1): 112-9
    • (2005) Brain Res , vol.1049 , Issue.1 , pp. 112-119
    • Pettus, E.H.1    Wright, D.W.2    Stein, D.G.3    Hoffman, S.W.4
  • 239
    • 0025905651 scopus 로고
    • Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells
    • Smith SS. Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells. Neuroscience 1991; 42: 309-20
    • (1991) Neuroscience , vol.42 , pp. 309-320
    • Smith, S.S.1
  • 240
    • 0030855406 scopus 로고    scopus 로고
    • Progesterone protects against lipid peroxidation following traumatic brain injury in rats
    • Roof RL, Hoffman SW, Stein DG. Progesterone protects against lipid peroxidation following traumatic brain injury in rats. Mol Chem Neuropathol 1997; 31: 1-11
    • (1997) Mol Chem Neuropathol , vol.31 , pp. 1-11
    • Roof, R.L.1    Hoffman, S.W.2    Stein, D.G.3
  • 243
    • 67849097743 scopus 로고    scopus 로고
    • Progesterone as a neuroprotective factor in traumatic and ischemic brain injury
    • Sayeed I, Stein DG. Progesterone as a neuroprotective factor in traumatic and ischemic brain injury. Prog Brain Res 2009; 175: 219-37
    • (2009) Prog Brain Res , vol.175 , pp. 219-237
    • Sayeed, I.1    Stein, D.G.2
  • 246
    • 84920026091 scopus 로고    scopus 로고
    • A Clinical Trial of Progesterone for Severe Traumatic Brain Injury
    • Skolnick BE, Maas AI, Narayan RK, et al. A Clinical Trial of Progesterone for Severe Traumatic Brain Injury. New Engl J Med 2014; 371: 2467-76
    • (2014) New Engl J Med , vol.371 , pp. 2467-2476
    • Skolnick, B.E.1    Maas, A.I.2    Narayan, R.K.3
  • 247
    • 84920059259 scopus 로고    scopus 로고
    • Very early administration of progesterone for acute traumatic brain injury
    • Wright DW, Yeatts SD, Silbergleit R, et al. Very early administration of progesterone for acute traumatic brain injury. New Engl J Med 2014; 371: 2457-66
    • (2014) New Engl J Med , vol.371 , pp. 2457-2466
    • Wright, D.W.1    Yeatts, S.D.2    Silbergleit, R.3
  • 248
    • 33846287960 scopus 로고    scopus 로고
    • Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: A multimodal analysis
    • Leonelli E, Bianchi R, Cavaletti G, et al. Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis. Neuroscience 2007; 144: 1293-304
    • (2007) Neuroscience , vol.144 , pp. 1293-1304
    • Leonelli, E.1    Bianchi, R.2    Cavaletti, G.3
  • 249
    • 80053482654 scopus 로고    scopus 로고
    • Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: Results of a randomized controlled trial
    • Wharton W, Baker LD, Gleason CE, et al. Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: results of a randomized controlled trial. J Alzheimers Dis 2011; 26: 495-505
    • (2011) J Alzheimers Dis , vol.26 , pp. 495-505
    • Wharton, W.1    Baker, L.D.2    Gleason, C.E.3
  • 250
    • 84871328175 scopus 로고    scopus 로고
    • Hormone therapy and Alzheimer disease dementia: New findings from the Cache County Study
    • Shao H, Breitner JC, Whitmer RA, Wang J, et al. Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology 2012; 79: 1846-52
    • (2012) Neurology , vol.79 , pp. 1846-1852
    • Shao, H.1    Breitner, J.C.2    Whitmer, R.A.3    Wang, J.4
  • 251
    • 84864381132 scopus 로고    scopus 로고
    • Minireview: Effects of different HT formulations on cognition
    • Maki PM. Minireview: effects of different HT formulations on cognition. Endocrinology 2012; 153: 3564-70
    • (2012) Endocrinology , vol.153 , pp. 3564-3570
    • Maki, P.M.1
  • 252
    • 84942819050 scopus 로고    scopus 로고
    • Estradiol and progesterone administration after pMCAO stimulates the neurological recovery and reduces the detrimental effect of ischemia mainly in hippocampus
    • Perez-Alvarez MJ, Mateos L, Alonso A, Wandosell F. estradiol and progesterone administration after pMCAO stimulates the neurological recovery and reduces the detrimental effect of ischemia mainly in hippocampus. Mol Neurobiol 2015; 52(3): 1690-703
    • (2015) Mol Neurobiol , vol.52 , Issue.3 , pp. 1690-1703
    • Perez-Alvarez, M.J.1    Mateos, L.2    Alonso, A.3    Wandosell, F.4
  • 253
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics2012 update a report from the american heart association
    • Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics2012 update a report from the american heart association. Circulation 2012; pp. e3-e218
    • (2012) Circulation , pp. ee3-e218
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 256
    • 0032587611 scopus 로고    scopus 로고
    • 17beta-estradiol reduces stroke injury in estrogen-deficient female animals
    • Rusa R, Alkayed NJ, Crain BJ, et al. 17beta-estradiol reduces stroke injury in estrogen-deficient female animals. Stroke 1999; 30: 1665-70
    • (1999) Stroke , vol.30 , pp. 1665-1670
    • Rusa, R.1    Alkayed, N.J.2    Crain, B.J.3
  • 257
    • 84876671834 scopus 로고    scopus 로고
    • Neuroprotective action of acute estrogens: Animal models of brain ischemia and clinical implications
    • Inagaki T, Etgen AM. Neuroprotective action of acute estrogens: Animal models of brain ischemia and clinical implications. Steroids 2013; 78: 597-606
    • (2013) Steroids , vol.78 , pp. 597-606
    • Inagaki, T.1    Etgen, A.M.2
  • 258
    • 0033981785 scopus 로고    scopus 로고
    • Estrogen receptor antagonist ICI182, 780 exacerbates ischemic injury in female mouse
    • Sawada M, Alkayed NJ, Goto S, et al. Estrogen receptor antagonist ICI182, 780 exacerbates ischemic injury in female mouse. J Cereb Blood Flow Metab 2000; 20: 112-8
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 112-118
    • Sawada, M.1    Alkayed, N.J.2    Goto, S.3
  • 259
    • 0035910642 scopus 로고    scopus 로고
    • Association of serum estrogen level and ischemic neuroprotection in female rats
    • Liao S, Chen W, Kuo J, Chen C. Association of serum estrogen level and ischemic neuroprotection in female rats. Neurosci Lett 2001; 297: 159-62
    • (2001) Neurosci Lett , vol.297 , pp. 159-162
    • Liao, S.1    Chen, W.2    Kuo, J.3    Chen, C.4
  • 261
    • 0031904678 scopus 로고    scopus 로고
    • Estrogen-Mediated Neuroprotection After Experimental Stroke in Male Rats
    • Toung TJK, Traystman RJ, Hurn PD. Estrogen-Mediated Neuroprotection After Experimental Stroke in Male Rats. Stroke 1998; 26: 1666-70
    • (1998) Stroke , vol.26 , pp. 1666-1670
    • Toung, T.1    Traystman, R.J.2    Hurn, P.D.3
  • 263
    • 0141535178 scopus 로고    scopus 로고
    • Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection
    • McCullough LD, Blizzard K, Simpson ER, Oz OK, Hurn PD. Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection. J Neurosci 2003; 23: 8701-5
    • (2003) J Neurosci , vol.23 , pp. 8701-8705
    • McCullough, L.D.1    Blizzard, K.2    Simpson, E.R.3    Oz, O.K.4    Hurn, P.D.5
  • 264
    • 0031552508 scopus 로고    scopus 로고
    • 17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors
    • Weaver CE, Park-Chung M, Gibbs TT, Farb DH. 17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors. Brain Res 1997; 761: 338-41
    • (1997) Brain Res , vol.761 , pp. 338-341
    • Weaver, C.E.1    Park-Chung, M.2    Gibbs, T.T.3    Farb, D.H.4
  • 265
  • 266
    • 34247533312 scopus 로고    scopus 로고
    • Estrogen-mediated neuroprotection in the cortex may require NMDA receptor activation
    • Connell BJ, Crosby KM, Richard MJ, Mayne MB, Saleh TM. Estrogen-mediated neuroprotection in the cortex may require NMDA receptor activation. Neuroscience 2007; 146: 160-9
    • (2007) Neuroscience , vol.146 , pp. 160-169
    • Connell, B.J.1    Crosby, K.M.2    Richard, M.J.3    Mayne, M.B.4    Saleh, T.M.5
  • 267
    • 79959274465 scopus 로고    scopus 로고
    • Differential neuroprotection of selective estrogen receptor agonists against autonomic dysfunction and ischemic cell death in permanent versus reperfusion injury
    • Connell BJ, Saleh TM. Differential neuroprotection of selective estrogen receptor agonists against autonomic dysfunction and ischemic cell death in permanent versus reperfusion injury. Adv Pharmacol Sci 2011; 2011: 976951-9
    • (2011) Adv Pharmacol Sci , vol.2011 , pp. 976951-976959
    • Connell, B.J.1    Saleh, T.M.2
  • 268
    • 79952850719 scopus 로고    scopus 로고
    • Oxidative stress in ischemic brain damage: Mechanisms of cell death and potential molecular targets for neuroprotection
    • Chen H, Yoshioka H, Kim GS, et al. Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection. Antioxid Redox Signal 2011; 14: 150-517
    • (2011) Antioxid Redox Signal , vol.14 , pp. 150-517
    • Chen, H.1    Yoshioka, H.2    Kim, G.S.3
  • 269
    • 58149268010 scopus 로고    scopus 로고
    • Glucose and NADPH oxidase drive neuronal superoxide formation in stroke
    • Suh SW, Shin BS, Ma H, et al. Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. Ann Neurol 2008; 64: 654-63
    • (2008) Ann Neurol , vol.64 , pp. 654-663
    • Suh, S.W.1    Shin, B.S.2    Ma, H.3
  • 270
    • 0033178294 scopus 로고    scopus 로고
    • Estradiol modulates bcl-2 in cerebral ischemia: A potential role for estrogen receptors
    • Dubal DB, Shughrue PJ, Wilson ME, Merchenthaler I, Wise PM. Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. J Neurosci 1999; 19(15): 6385-93
    • (1999) J Neurosci , vol.19 , Issue.15 , pp. 6385-6393
    • Dubal, D.B.1    Shughrue, P.J.2    Wilson, M.E.3    Merchenthaler, I.4    Wise, P.M.5
  • 271
    • 0348109349 scopus 로고    scopus 로고
    • Estradiol attenuates programmed cell death after stroke-like injury
    • Rau SW, Dubal DB, Böttner M, Gerhold LM, Wise PM. Estradiol attenuates programmed cell death after stroke-like injury. J Neurosci 2003; 23: 11420-26
    • (2003) J Neurosci , vol.23 , pp. 11420-11426
    • Rau, S.W.1    Dubal, D.B.2    Böttner, M.3    Gerhold, L.M.4    Wise, P.M.5
  • 272
    • 57449090234 scopus 로고    scopus 로고
    • Estrogen inhibits Fas-mediated apoptosis in experimental stroke
    • Jia J, Guan D, Zhu W, et al. Estrogen inhibits Fas-mediated apoptosis in experimental stroke. Exp Neurol 2009; 215: 5
    • (2009) Exp Neurol , vol.215
    • Jia, J.1    Guan, D.2    Zhu, W.3
  • 273
  • 274
    • 33847062554 scopus 로고    scopus 로고
    • MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia
    • Jover-Mengual T, Zukin RS, Etgen AM. MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia. Endocrinology 2007; 148: 1131-43
    • (2007) Endocrinology , vol.148 , pp. 1131-1143
    • Jover-Mengual, T.1    Zukin, R.S.2    Etgen, A.M.3
  • 275
    • 33845960245 scopus 로고    scopus 로고
    • Estradiol prevents the injury-induced decrease of 90 ribosomal S6 kinase (P90RSK) and Bad phosphorylation
    • Koh PO. Estradiol prevents the injury-induced decrease of 90 ribosomal S6 kinase (p90RSK) and Bad phosphorylation. Neurosci Lett 2007; 412: 68-72
    • (2007) Neurosci Lett , vol.412 , pp. 68-72
    • Koh, P.O.1
  • 276
    • 84864652658 scopus 로고    scopus 로고
    • Effects of global ischemia and estradiol pretreatment on phosphorylation of Akt, CREB and STAT3 in hippocampal CA1 of young and middle-aged female rats
    • De Butte-Smith M, Zukin RS, Etgen AM. Effects of global ischemia and estradiol pretreatment on phosphorylation of Akt, CREB and STAT3 in hippocampal CA1 of young and middle-aged female rats. Brain Res 2012; 1471: 118-28
    • (2012) Brain Res , vol.1471 , pp. 118-128
    • De Butte-Smith, M.1    Zukin, R.S.2    Etgen, A.M.3
  • 277
    • 45549105772 scopus 로고    scopus 로고
    • Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke
    • Sawe N, Steinberg G, Zhao H. Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke. J Neurosci Res 2008; 86: 165-969
    • (2008) J Neurosci Res , vol.86 , pp. 165-969
    • Sawe, N.1    Steinberg, G.2    Zhao, H.3
  • 278
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
    • Pap M, Cooper GM. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J Biol Chem 1998; 273: 19929-32
    • (1998) J Biol Chem , vol.273 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 280
    • 36448946877 scopus 로고    scopus 로고
    • Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia
    • Farr TD, Carswell HV, Gsell W, Macrae IM. Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia. Brain Res 2007; 1185: 275-82
    • (2007) Brain Res , vol.1185 , pp. 275-282
    • Farr, T.D.1    Carswell, H.V.2    Gsell, W.3    Macrae, I.M.4
  • 281
    • 79959274465 scopus 로고    scopus 로고
    • Differential neuroprotection of selective estrogen receptor agonists against autonomic dysfunction and ischemic cell death in permanent versus reperfusion injury
    • Connell BJ, Saleh TM. Differential neuroprotection of selective estrogen receptor agonists against autonomic dysfunction and ischemic cell death in permanent versus reperfusion injury. Adv Pharmacol Sci 2011; 2011: 976-951
    • (2011) Adv Pharmacol Sci , vol.2011 , pp. 951-976
    • Connell, B.J.1    Saleh, T.M.2
  • 282
    • 0035852657 scopus 로고    scopus 로고
    • Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury
    • Dubal DB, Zhu H, Yu J, et al. Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury. Proc Natl Acad Sci USA 2001; 98: 1952-7
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1952-1957
    • Dubal, D.B.1    Zhu, H.2    Yu, J.3
  • 283
    • 33646779843 scopus 로고    scopus 로고
    • Differential modulation of estrogen receptors (ERs) in ischemic brain injury: A role for ERalpha in estradiol-mediated protection against delayed cell death
    • Dubal DB, Rau SW, Shughrue PJ, et al. Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death. Endocrinology 2006; 147: 3076-84
    • (2006) Endocrinology , vol.147 , pp. 3076-3084
    • Dubal, D.B.1    Rau, S.W.2    Shughrue, P.J.3
  • 284
    • 34548681666 scopus 로고    scopus 로고
    • Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons
    • Zhao L, Brinton RD. Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons. Brain Res 2007; 1172: 48-59
    • (2007) Brain Res , vol.1172 , pp. 48-59
    • Zhao, L.1    Brinton, R.D.2
  • 285
    • 77952760799 scopus 로고    scopus 로고
    • Estradiol and G1 reduce infarct size and improve immunosuppression after experimental stroke
    • Zhang B, Subramanian S, Dziennis S, et al. Estradiol and G1 reduce infarct size and improve immunosuppression after experimental stroke. J Immunol 2010; 184: 4087-94
    • (2010) J Immunol , vol.184 , pp. 4087-4094
    • Zhang, B.1    Subramanian, S.2    Dziennis, S.3
  • 286
    • 18844376360 scopus 로고    scopus 로고
    • Astrocytederived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: Involvement of nonclassical genomic signaling pathways
    • Dhandapani KM, Wade FM, Mahesh VB, Brann DW. Astrocytederived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: involvement of nonclassical genomic signaling pathways. Endocrinology 2005; 146: 2749-59
    • (2005) Endocrinology , vol.146 , pp. 2749-2759
    • Dhandapani, K.M.1    Wade, F.M.2    Mahesh, V.B.3    Brann, D.W.4
  • 288
    • 34547291144 scopus 로고    scopus 로고
    • Evidence to implicate early modulation of interleukin 1 expression in the neuroprotection afforded by 17 Estradiol in male rats undergone transient middle cerebral artery occlusion
    • Giacinto Bagetta MTC, Stuart AL, USA: Academic Press
    • Chiappetta O, Gliozzi M, Siviglia E, et al. Evidence to implicate early modulation of interleukin 1 expression in the neuroprotection afforded by 17 Estradiol in male rats undergone transient middle cerebral artery occlusion. In: Giacinto Bagetta MTC, Stuart AL, Eds. International Review of Neurobiology. USA: Academic Press 2007; pp. 357-372
    • (2007) International Review of Neurobiology , pp. 357-372
    • Chiappetta, O.1    Gliozzi, M.2    Siviglia, E.3
  • 289
    • 34347244941 scopus 로고    scopus 로고
    • Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions
    • Suzuki S, Brown CM, Dela Cruz CD, Yang E, Bridwell DA, Wise PM. Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions. Proc Natl Acad Sci USA 2007; 104: 6013-8
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6013-6018
    • Suzuki, S.1    Brown, C.M.2    Dela Cruz, C.D.3    Yang, E.4    Bridwell, D.A.5    Wise, P.M.6
  • 290
    • 0034332969 scopus 로고    scopus 로고
    • Female sex steroids: Effects upon microglial cell activation
    • Drew PD, Chavis JA. Female sex steroids: effects upon microglial cell activation. J Neuroimmunol 2000; 111: 77-85
    • (2000) J Neuroimmunol , vol.111 , pp. 77-85
    • Drew, P.D.1    Chavis, J.A.2
  • 291
    • 0026690043 scopus 로고
    • Progesterone treatment attenuates brain edema following contusion injury in male and female rats
    • Roof RL, Stein DG. Progesterone treatment attenuates brain edema following contusion injury in male and female rats. Restor Neurol Neurosci 1992; 4: 425-7
    • (1992) Restor Neurol Neurosci , vol.4 , pp. 425-427
    • Roof, R.L.1    Stein, D.G.2
  • 292
    • 0034850817 scopus 로고    scopus 로고
    • Serum progesterone levels correlatewith decreased cerebral edema aftertraumatic brain injury in male rats
    • Wright DW, Bauer ME, Hoffman SW, Stein DG. Serum progesterone levels correlatewith decreased cerebral edema aftertraumatic brain injury in male rats. J Neurotrauma 2001; 18: 901-9
    • (2001) J Neurotrauma , vol.18 , pp. 901-909
    • Wright, D.W.1    Bauer, M.E.2    Hoffman, S.W.3    Stein, D.G.4
  • 293
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • He J, Evans CO, Hoffman SW, Oyesiku NM, Stein DG. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. Exp Neurol 2004; 189: 404-12
    • (2004) Exp Neurol , vol.189 , pp. 404-412
    • He, J.1    Evans, C.O.2    Hoffman, S.W.3    Oyesiku, N.M.4    Stein, D.G.5
  • 295
    • 18144409121 scopus 로고    scopus 로고
    • Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia
    • Gibson CL, Constantin D, Prior MJW, Bath PMW, Murphy SP. Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia. Exp Neurol 2005; 193: 522-30
    • (2005) Exp Neurol , vol.193 , pp. 522-530
    • Gibson, C.L.1    Constantin, D.2    Prior, M.3    Bath, P.4    Murphy, S.P.5
  • 297
    • 23944441957 scopus 로고    scopus 로고
    • Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: Pharmacological and behavioral effects
    • Shen H, Gong QH, Yuan M, Smith SS. Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects. Neuropharmacology 2005; 49: 573-86
    • (2005) Neuropharmacology , vol.49 , pp. 573-586
    • Shen, H.1    Gong, Q.H.2    Yuan, M.3    Smith, S.S.4
  • 298
    • 0029671013 scopus 로고    scopus 로고
    • GABAA-receptormediated effects of progesterone, its ring-A-reduced metabolites and synthetic neuroactive steroids on neurogenic oedema in the rat meninges
    • Limmroth V, Lee WS, Moskowitz MA. GABAA-receptormediated effects of progesterone, its ring-A-reduced metabolites and synthetic neuroactive steroids on neurogenic oedema in the rat meninges. Br J Pharmacol 1996; 117: 99-104
    • (1996) Br J Pharmacol , vol.117 , pp. 99-104
    • Limmroth, V.1    Lee, W.S.2    Moskowitz, M.A.3
  • 299
    • 0034128362 scopus 로고    scopus 로고
    • Gender differences in acute CNS trauma and stroke: Neuroprotective effects of estrogen and progesterone
    • Roof RL, Hall ED. Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone. J Neurotrauma 2000; 17: 367-88
    • (2000) J Neurotrauma , vol.17 , pp. 367-388
    • Roof, R.L.1    Hall, E.D.2
  • 300
    • 79954735874 scopus 로고    scopus 로고
    • Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female rats
    • Dang J, Mitkari B, Kipp M, Beyer C. Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female rats. Brain Behav Immun 2011; 25: 715-26
    • (2011) Brain Behav Immun , vol.25 , pp. 715-726
    • Dang, J.1    Mitkari, B.2    Kipp, M.3    Beyer, C.4
  • 301
    • 84861186845 scopus 로고    scopus 로고
    • Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway
    • Ishrat T, Sayeed I, Atif F, Hua F, Stein DG. Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway. Neuroscience 2012; 210: 442-50
    • (2012) Neuroscience , vol.210 , pp. 442-450
    • Ishrat, T.1    Sayeed, I.2    Atif, F.3    Hua, F.4    Stein, D.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.