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Volumn 1833, Issue 5, 2013, Pages 1052-1064

Oestradiol signalling through the Akt-mTORC1-S6K1

Author keywords

Estradiol cytoplasmic signalling; Estrogen; Rheb activation; S6 kinase activation

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RHEB PROTEIN; S6 KINASE;

EID: 84874547373     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2012.12.019     Document Type: Article
Times cited : (17)

References (73)
  • 1
    • 0346022988 scopus 로고    scopus 로고
    • Subcellular localization of estrogen receptor beta in mouse hippocampus
    • Nishio M., Kuroki Y., Watanabe Y. Subcellular localization of estrogen receptor beta in mouse hippocampus. Neurosci. Lett. 2004, 355:109-112.
    • (2004) Neurosci. Lett. , vol.355 , pp. 109-112
    • Nishio, M.1    Kuroki, Y.2    Watanabe, Y.3
  • 3
    • 0141535033 scopus 로고    scopus 로고
    • Neurite-localized estrogen receptor-alpha mediates rapid signaling by estrogen
    • Xu Y., Traystman R.J., Hurn P.D., Wang M.M. Neurite-localized estrogen receptor-alpha mediates rapid signaling by estrogen. J. Neurosci. Res. 2003, 74:1-11.
    • (2003) J. Neurosci. Res. , vol.74 , pp. 1-11
    • Xu, Y.1    Traystman, R.J.2    Hurn, P.D.3    Wang, M.M.4
  • 4
    • 0025411855 scopus 로고
    • Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
    • Gould E., Woolley C.S., Frankfurt M., McEwen B.S. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J. Neurosci. 1990, 10:1286-1291.
    • (1990) J. Neurosci. , vol.10 , pp. 1286-1291
    • Gould, E.1    Woolley, C.S.2    Frankfurt, M.3    McEwen, B.S.4
  • 5
    • 0026627947 scopus 로고
    • Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat
    • Woolley C.S., McEwen B.S. Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J. Neurosci. 1992, 12:2549-2554.
    • (1992) J. Neurosci. , vol.12 , pp. 2549-2554
    • Woolley, C.S.1    McEwen, B.S.2
  • 6
    • 67449123067 scopus 로고    scopus 로고
    • Control of CNS neuronal excitability by estrogens via membrane-initiated signaling
    • Kelly M.J., Ronnekleiv O.K. Control of CNS neuronal excitability by estrogens via membrane-initiated signaling. Mol. Cell. Endocrinol. 2009, 308:17-25.
    • (2009) Mol. Cell. Endocrinol. , vol.308 , pp. 17-25
    • Kelly, M.J.1    Ronnekleiv, O.K.2
  • 9
    • 0037202286 scopus 로고    scopus 로고
    • Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus
    • Cardona-Gomez G.P., Mendez P., Garcia-Segura L.M. Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus. Brain Res. Mol. Brain Res. 2002, 107:80-88.
    • (2002) Brain Res. Mol. Brain Res. , vol.107 , pp. 80-88
    • Cardona-Gomez, G.P.1    Mendez, P.2    Garcia-Segura, L.M.3
  • 10
    • 1642375658 scopus 로고    scopus 로고
    • Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus
    • Cardona-Gomez P., Perez M., Avila J., Garcia-Segura L.M., Wandosell F. Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus. Mol. Cell. Neurosci. 2004, 25:363-373.
    • (2004) Mol. Cell. Neurosci. , vol.25 , pp. 363-373
    • Cardona-Gomez, P.1    Perez, M.2    Avila, J.3    Garcia-Segura, L.M.4    Wandosell, F.5
  • 11
    • 11844260672 scopus 로고    scopus 로고
    • Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators
    • Jiang H., Guo W., Liang X., Rao Y. Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell 2005, 120:123-135.
    • (2005) Cell , vol.120 , pp. 123-135
    • Jiang, H.1    Guo, W.2    Liang, X.3    Rao, Y.4
  • 12
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K., Li Y., Zhu T., Wu J., Guan K.L. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 2002, 4:648-657.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 13
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
    • Manning B.D., Tee A.R., Logsdon M.N., Blenis J., Cantley L.C. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell 2002, 10:151-162.
    • (2002) Mol. Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 15
    • 34548864370 scopus 로고    scopus 로고
    • Culturing hippocampal neurons
    • Kaech S., Banker G. Culturing hippocampal neurons. Nat. Protoc. 2006, 1:2406-2415.
    • (2006) Nat. Protoc. , vol.1 , pp. 2406-2415
    • Kaech, S.1    Banker, G.2
  • 16
    • 38849099839 scopus 로고    scopus 로고
    • Pharmacological inhibition of GSK-3 is not strictly correlated with a decrease in tyrosine phosphorylation of residues 216/279
    • Simon D., Benitez M.J., Gimenez-Cassina A., Garrido J.J., Bhat R.V., Diaz-Nido J., Wandosell F. Pharmacological inhibition of GSK-3 is not strictly correlated with a decrease in tyrosine phosphorylation of residues 216/279. J. Neurosci. Res. 2008, 86:668-674.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 668-674
    • Simon, D.1    Benitez, M.J.2    Gimenez-Cassina, A.3    Garrido, J.J.4    Bhat, R.V.5    Diaz-Nido, J.6    Wandosell, F.7
  • 17
    • 42449094187 scopus 로고    scopus 로고
    • Messing up with traffic: different effects of antipsychotic agents on glutamate receptor complexes in vivo
    • Del'guidice T., Beaulieu J.M. Messing up with traffic: different effects of antipsychotic agents on glutamate receptor complexes in vivo. Mol. Pharmacol. 2008, 73:1339-1342.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 1339-1342
    • Del'guidice, T.1    Beaulieu, J.M.2
  • 18
    • 0037117409 scopus 로고    scopus 로고
    • Identification of a conserved motif required for mTOR signaling
    • Schalm S.S., Blenis J. Identification of a conserved motif required for mTOR signaling. Curr. Biol. 2002, 12:632-639.
    • (2002) Curr. Biol. , vol.12 , pp. 632-639
    • Schalm, S.S.1    Blenis, J.2
  • 19
    • 77953693730 scopus 로고    scopus 로고
    • Semi-automated Sholl analysis for quantifying changes in growth and differentiation of neurons and glia
    • Gensel J.C., Schonberg D.L., Alexander J.K., McTigue D.M., Popovich P.G. Semi-automated Sholl analysis for quantifying changes in growth and differentiation of neurons and glia. J. Neurosci. Methods 2010, 190:71-79.
    • (2010) J. Neurosci. Methods , vol.190 , pp. 71-79
    • Gensel, J.C.1    Schonberg, D.L.2    Alexander, J.K.3    McTigue, D.M.4    Popovich, P.G.5
  • 20
    • 0035498811 scopus 로고    scopus 로고
    • Nongenomic mechanism mediates estradiol stimulation of axon growth in male rat hypothalamic neurons in vitro
    • Cambiasso M.J., Carrer H.F. Nongenomic mechanism mediates estradiol stimulation of axon growth in male rat hypothalamic neurons in vitro. J. Neurosci. Res. 2001, 66:475-481.
    • (2001) J. Neurosci. Res. , vol.66 , pp. 475-481
    • Cambiasso, M.J.1    Carrer, H.F.2
  • 21
    • 0026047799 scopus 로고
    • Estrogen-enhanced neurite growth: evidence for a selective induction of Tau and stable microtubules
    • Ferreira A., Caceres A. Estrogen-enhanced neurite growth: evidence for a selective induction of Tau and stable microtubules. J. Neurosci. 1991, 11:392-400.
    • (1991) J. Neurosci. , vol.11 , pp. 392-400
    • Ferreira, A.1    Caceres, A.2
  • 22
    • 27644508001 scopus 로고    scopus 로고
    • Estrogen receptor alpha mediates neuronal differentiation and neuroprotection in PC12 cells: critical role of the A/B domain of the receptor
    • Merot Y., Ferriere F., Debroas E., Flouriot G., Duval D., Saligaut C. Estrogen receptor alpha mediates neuronal differentiation and neuroprotection in PC12 cells: critical role of the A/B domain of the receptor. J. Mol. Endocrinol. 2005, 35:257-267.
    • (2005) J. Mol. Endocrinol. , vol.35 , pp. 257-267
    • Merot, Y.1    Ferriere, F.2    Debroas, E.3    Flouriot, G.4    Duval, D.5    Saligaut, C.6
  • 23
    • 0036150795 scopus 로고    scopus 로고
    • Estradiol (E2) enhances neurite outgrowth by repressing glial fibrillary acidic protein expression and reorganizing laminin
    • Rozovsky I., Wei M., Stone D.J., Zanjani H., Anderson C.P., Morgan T.E., Finch C.E. Estradiol (E2) enhances neurite outgrowth by repressing glial fibrillary acidic protein expression and reorganizing laminin. Endocrinology 2002, 143:636-646.
    • (2002) Endocrinology , vol.143 , pp. 636-646
    • Rozovsky, I.1    Wei, M.2    Stone, D.J.3    Zanjani, H.4    Anderson, C.P.5    Morgan, T.E.6    Finch, C.E.7
  • 24
    • 0142216502 scopus 로고    scopus 로고
    • Beta-estradiol influences differentiation of hippocampal neurons in vitro through an estrogen receptor-mediated process
    • Audesirk T., Cabell L., Kern M., Audesirk G. Beta-estradiol influences differentiation of hippocampal neurons in vitro through an estrogen receptor-mediated process. Neuroscience 2003, 121:927-934.
    • (2003) Neuroscience , vol.121 , pp. 927-934
    • Audesirk, T.1    Cabell, L.2    Kern, M.3    Audesirk, G.4
  • 27
    • 3543077099 scopus 로고    scopus 로고
    • Estrogen reduces the neurite growth of serotonergic cells expressing estrogen receptors
    • Lu H., Nishi M., Matsuda K., Kawata M. Estrogen reduces the neurite growth of serotonergic cells expressing estrogen receptors. Neurosci. Res. 2004, 50:23-28.
    • (2004) Neurosci. Res. , vol.50 , pp. 23-28
    • Lu, H.1    Nishi, M.2    Matsuda, K.3    Kawata, M.4
  • 28
    • 0037430850 scopus 로고    scopus 로고
    • Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain
    • Mendez P., Azcoitia I., Garcia-Segura L.M. Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain. Brain Res. Mol. Brain Res. 2003, 112:170-176.
    • (2003) Brain Res. Mol. Brain Res. , vol.112 , pp. 170-176
    • Mendez, P.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 29
    • 69949167076 scopus 로고    scopus 로고
    • Involvement of Akt in neurite outgrowth
    • Read D.E., Gorman A.M. Involvement of Akt in neurite outgrowth. Cell. Mol. Life Sci. 2009, 66:2975-2984.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 2975-2984
    • Read, D.E.1    Gorman, A.M.2
  • 31
    • 1842614409 scopus 로고    scopus 로고
    • PIP3 is involved in neuronal polarization and axon formation
    • Menager C., Arimura N., Fukata Y., Kaibuchi K. PIP3 is involved in neuronal polarization and axon formation. J. Neurochem. 2004, 89:109-118.
    • (2004) J. Neurochem. , vol.89 , pp. 109-118
    • Menager, C.1    Arimura, N.2    Fukata, Y.3    Kaibuchi, K.4
  • 32
    • 0037162282 scopus 로고    scopus 로고
    • Casein kinase 1: a Wnt'er of disconnect
    • Polakis P. Casein kinase 1: a Wnt'er of disconnect. Curr. Biol. 2002, 12:R499-R501.
    • (2002) Curr. Biol. , vol.12
    • Polakis, P.1
  • 33
    • 5344281149 scopus 로고    scopus 로고
    • Multiple functions for the cadherin/catenin complex during neuronal development
    • Yu X., Malenka R.C. Multiple functions for the cadherin/catenin complex during neuronal development. Neuropharmacology 2004, 47:779-786.
    • (2004) Neuropharmacology , vol.47 , pp. 779-786
    • Yu, X.1    Malenka, R.C.2
  • 36
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho E.H., Zhang T., Domon C., Joo C.K., Freund J.N., Costantini F. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 2002, 22:1172-1183.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 37
    • 70350455151 scopus 로고    scopus 로고
    • Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway
    • Morita T., Sobue K. Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway. J. Biol. Chem. 2009, 284:27734-27745.
    • (2009) J. Biol. Chem. , vol.284 , pp. 27734-27745
    • Morita, T.1    Sobue, K.2
  • 40
    • 52949126962 scopus 로고    scopus 로고
    • Constitutively active Rheb induces oncogenic transformation
    • Jiang H., Vogt P.K. Constitutively active Rheb induces oncogenic transformation. Oncogene 2008, 27:5729-5740.
    • (2008) Oncogene , vol.27 , pp. 5729-5740
    • Jiang, H.1    Vogt, P.K.2
  • 42
    • 33744521542 scopus 로고    scopus 로고
    • Rheb activation of mTOR and S6K1 signaling
    • Hanrahan J., Blenis J. Rheb activation of mTOR and S6K1 signaling. Methods Enzymol. 2006, 407:542-555.
    • (2006) Methods Enzymol. , vol.407 , pp. 542-555
    • Hanrahan, J.1    Blenis, J.2
  • 43
    • 61449135038 scopus 로고    scopus 로고
    • Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons
    • Noel S.D., Keen K.L., Baumann D.I., Filardo E.J., Terasawa E. Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons. Mol. Endocrinol. 2009, 23:349-359.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 349-359
    • Noel, S.D.1    Keen, K.L.2    Baumann, D.I.3    Filardo, E.J.4    Terasawa, E.5
  • 44
    • 34250322219 scopus 로고    scopus 로고
    • Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system
    • Brailoiu E., Dun S.L., Brailoiu G.C., Mizuo K., Sklar L.A., Oprea T.I., Prossnitz E.R., Dun N.J. Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J. Endocrinol. 2007, 193:311-321.
    • (2007) J. Endocrinol. , vol.193 , pp. 311-321
    • Brailoiu, E.1    Dun, S.L.2    Brailoiu, G.C.3    Mizuo, K.4    Sklar, L.A.5    Oprea, T.I.6    Prossnitz, E.R.7    Dun, N.J.8
  • 45
    • 77955483340 scopus 로고    scopus 로고
    • ERbeta in CNS: new roles in development and function
    • Fan X., Xu H., Warner M., Gustafsson J.A. ERbeta in CNS: new roles in development and function. Prog. Brain Res. 2010, 181:233-250.
    • (2010) Prog. Brain Res. , vol.181 , pp. 233-250
    • Fan, X.1    Xu, H.2    Warner, M.3    Gustafsson, J.A.4
  • 46
    • 58149474519 scopus 로고    scopus 로고
    • Different outcomes of unliganded and liganded estrogen receptor-alpha on neurite outgrowth in PC12 cells
    • Merot Y., Ferriere F., Gailhouste L., Huet G., Percevault F., Saligaut C., Flouriot G. Different outcomes of unliganded and liganded estrogen receptor-alpha on neurite outgrowth in PC12 cells. Endocrinology 2009, 150:200-211.
    • (2009) Endocrinology , vol.150 , pp. 200-211
    • Merot, Y.1    Ferriere, F.2    Gailhouste, L.3    Huet, G.4    Percevault, F.5    Saligaut, C.6    Flouriot, G.7
  • 47
    • 17844399257 scopus 로고    scopus 로고
    • Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analysing neuroprotective mechanisms
    • Mendez P., Azcoitia I., Garcia-Segura L.M. Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analysing neuroprotective mechanisms. J. Endocrinol. 2005, 185:11-17.
    • (2005) J. Endocrinol. , vol.185 , pp. 11-17
    • Mendez, P.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 48
    • 34547095246 scopus 로고    scopus 로고
    • Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells
    • Song R.X., Zhang Z., Chen Y., Bao Y., Santen R.J. Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells. Endocrinology 2007, 148:4091-4101.
    • (2007) Endocrinology , vol.148 , pp. 4091-4101
    • Song, R.X.1    Zhang, Z.2    Chen, Y.3    Bao, Y.4    Santen, R.J.5
  • 49
    • 78650968836 scopus 로고    scopus 로고
    • Interactions between IGF-I, estrogen receptor-alpha (ERalpha), and ERbeta in regulating growth/apoptosis of MCF-7 human breast cancer cells
    • Mendoza R.A., Enriquez M.I., Mejia S.M., Moody E.E., Thordarson G. Interactions between IGF-I, estrogen receptor-alpha (ERalpha), and ERbeta in regulating growth/apoptosis of MCF-7 human breast cancer cells. J. Endocrinol. 2010, 208:1-9.
    • (2010) J. Endocrinol. , vol.208 , pp. 1-9
    • Mendoza, R.A.1    Enriquez, M.I.2    Mejia, S.M.3    Moody, E.E.4    Thordarson, G.5
  • 50
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    • Delcommenne M., Tan C., Gray V., Rue L., Woodgett J., Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:11211-11216.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 52
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through beta-catenin
    • Moon R.T., Bowerman B., Boutros M., Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science 2002, 296:1644-1646.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 53
    • 30544431846 scopus 로고    scopus 로고
    • Neurite outgrowth involves adenomatous polyposis coli protein and beta-catenin
    • Votin V., Nelson W.J., Barth A.I. Neurite outgrowth involves adenomatous polyposis coli protein and beta-catenin. J. Cell Sci. 2005, 118:5699-5708.
    • (2005) J. Cell Sci. , vol.118 , pp. 5699-5708
    • Votin, V.1    Nelson, W.J.2    Barth, A.I.3
  • 54
    • 58149263162 scopus 로고    scopus 로고
    • Coordinated changes in dendritic arborization and synaptic strength during neural circuit development
    • Peng Y.R., He S., Marie H., Zeng S.Y., Ma J., Tan Z.J., Lee S.Y., Malenka R.C., Yu X. Coordinated changes in dendritic arborization and synaptic strength during neural circuit development. Neuron 2009, 61:71-84.
    • (2009) Neuron , vol.61 , pp. 71-84
    • Peng, Y.R.1    He, S.2    Marie, H.3    Zeng, S.Y.4    Ma, J.5    Tan, Z.J.6    Lee, S.Y.7    Malenka, R.C.8    Yu, X.9
  • 55
    • 70449473508 scopus 로고    scopus 로고
    • Lipid raft-targeted Akt promotes axonal branching and growth cone expansion via mTOR and Rac1, respectively
    • Grider M.H., Park D., Spencer D.M., Shine H.D. Lipid raft-targeted Akt promotes axonal branching and growth cone expansion via mTOR and Rac1, respectively. J. Neurosci. Res. 2009, 87:3033-3042.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 3033-3042
    • Grider, M.H.1    Park, D.2    Spencer, D.M.3    Shine, H.D.4
  • 57
    • 33750302398 scopus 로고    scopus 로고
    • Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain
    • Yu J., Henske E.P. Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain. Cancer Res. 2006, 66:9461-9466.
    • (2006) Cancer Res. , vol.66 , pp. 9461-9466
    • Yu, J.1    Henske, E.P.2
  • 60
    • 33746190665 scopus 로고    scopus 로고
    • Binding of Cdc42 to phospholipase D1 is important in neurite outgrowth of neural stem cells
    • Yoon M.S., Cho C.H., Lee K.S., Han J.S. Binding of Cdc42 to phospholipase D1 is important in neurite outgrowth of neural stem cells. Biochem. Biophys. Res. Commun. 2006, 347:594-600.
    • (2006) Biochem. Biophys. Res. Commun. , vol.347 , pp. 594-600
    • Yoon, M.S.1    Cho, C.H.2    Lee, K.S.3    Han, J.S.4
  • 62
    • 45849110311 scopus 로고    scopus 로고
    • Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function
    • Meikle L., Pollizzi K., Egnor A., Kramvis I., Lane H., Sahin M., Kwiatkowski D.J. Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function. J. Neurosci. 2008, 28:5422-5432.
    • (2008) J. Neurosci. , vol.28 , pp. 5422-5432
    • Meikle, L.1    Pollizzi, K.2    Egnor, A.3    Kramvis, I.4    Lane, H.5    Sahin, M.6    Kwiatkowski, D.J.7
  • 63
    • 78650239404 scopus 로고    scopus 로고
    • Functions and regulation of the 70kDa ribosomal S6 kinases
    • Fenton T.R., Gout I.T. Functions and regulation of the 70kDa ribosomal S6 kinases. Int. J. Biochem. Cell Biol. 2010, 43:47-59.
    • (2010) Int. J. Biochem. Cell Biol. , vol.43 , pp. 47-59
    • Fenton, T.R.1    Gout, I.T.2
  • 64
    • 7744224557 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites
    • Takei N., Inamura N., Kawamura M., Namba H., Hara K., Yonezawa K., Nawa H. Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites. J. Neurosci. 2004, 24:9760-9769.
    • (2004) J. Neurosci. , vol.24 , pp. 9760-9769
    • Takei, N.1    Inamura, N.2    Kawamura, M.3    Namba, H.4    Hara, K.5    Yonezawa, K.6    Nawa, H.7
  • 66
    • 65249190250 scopus 로고    scopus 로고
    • S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation
    • Yamnik R.L., Digilova A., Davis D.C., Brodt Z.N., Murphy C.J., Holz M.K. S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation. J. Biol. Chem. 2009, 284:6361-6369.
    • (2009) J. Biol. Chem. , vol.284 , pp. 6361-6369
    • Yamnik, R.L.1    Digilova, A.2    Davis, D.C.3    Brodt, Z.N.4    Murphy, C.J.5    Holz, M.K.6
  • 69
    • 0033583284 scopus 로고    scopus 로고
    • The role of local actin instability in axon formation
    • Bradke F., Dotti C.G. The role of local actin instability in axon formation. Science 1999, 283:1931-1934.
    • (1999) Science , vol.283 , pp. 1931-1934
    • Bradke, F.1    Dotti, C.G.2
  • 70
    • 0141864656 scopus 로고    scopus 로고
    • RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability
    • Da Silva J.S., Medina M., Zuliani C., Di Nardo A., Witke W., Dotti C.G. RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability. J. Cell Biol. 2003, 162:1267-1279.
    • (2003) J. Cell Biol. , vol.162 , pp. 1267-1279
    • Da Silva, J.S.1    Medina, M.2    Zuliani, C.3    Di Nardo, A.4    Witke, W.5    Dotti, C.G.6
  • 71
    • 77954244905 scopus 로고    scopus 로고
    • Extra-nuclear signaling of ERalpha to the actin cytoskeleton in the central nervous system
    • Sanchez A.M., Simoncini T. Extra-nuclear signaling of ERalpha to the actin cytoskeleton in the central nervous system. Steroids 2010, 75:528-532.
    • (2010) Steroids , vol.75 , pp. 528-532
    • Sanchez, A.M.1    Simoncini, T.2
  • 72
    • 78049352549 scopus 로고    scopus 로고
    • Estrogen receptor-{alpha} promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP
    • Sanchez A.M., Flamini M.I., Baldacci C., Goglia L., Genazzani A.R., Simoncini T. Estrogen receptor-{alpha} promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP. Mol. Endocrinol. 2010, 24:2114-2125.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 2114-2125
    • Sanchez, A.M.1    Flamini, M.I.2    Baldacci, C.3    Goglia, L.4    Genazzani, A.R.5    Simoncini, T.6
  • 73
    • 77957134414 scopus 로고    scopus 로고
    • Estrogen-induced activation of extracellular signal-regulated kinase signaling triggers dendritic resident mRNA translation
    • Sarkar S.N., Smith L.T., Logan S.M., Simpkins J.W. Estrogen-induced activation of extracellular signal-regulated kinase signaling triggers dendritic resident mRNA translation. Neuroscience 2010, 170:1080-1085.
    • (2010) Neuroscience , vol.170 , pp. 1080-1085
    • Sarkar, S.N.1    Smith, L.T.2    Logan, S.M.3    Simpkins, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.